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ARISE

Career Accelerator for Research Infrastructure Scientists

The Instituto Gulbenkian Ciência (IGC)

https://gulbenkian.pt/ciencia/

As part of the Calouste Gulbenkian Foundation, the Instituto Gulbenkian Ciência (IGC) is an excellent institute dedicated to biological and biomedical research and innovative postgraduate training, placing science at the heart of society. The IGC comprises 400 Researchers, 33 Research Groups, 10 Facilities, and 13 Support Services and is focused on solving tomorrow’s challenges. Research is developed in an environment of intellectual and
financial autonomy, with full access to state-of-the-art facilities and services.

The IGC research programs cover a wide range of domains and are at the interface of different disciplines, studying organisms, from bacteria to humans. These include cell, developmental, evolutionary, computational biology, physiology and host microbeinteractions, sociobiology, and biophysics. The IGC has been exceptionally
productive in publishing high-quality papers and in competing for national and international grants. The quality of the work published is underscored by the journal in which the works appear and the number of citations. The number of invitations to conferences, editorial boards, and grant panels all testifies the IGC recognition.
Integrated into national and international research structures and networks, the IGC strategy also incorporates investments in public dissemination and outreach activities.

As a partner in this project, the IGC intends to cooperate with the EMBL towards training of the Fellows. The IGC can host up to two Fellows per year in the period 2021-2024 through secondments and introduce them to the ways of working, instrumentation and procedures at the IGC. Duration of secondments will be between 2 and 6 months and will be arranged in communication with the Fellow. Fellows who will do secondments at the IGC will
come from the field related or complementary to the field of work of the IGC. At the IGC, Fellows will have a possibility to be integrated into the advanced imaging facility (light microscopy), bioinformatics, flow cytometry and antibody, electron microscopy, and / or histopathology facilities. In these facilities the Fellows will have a
chance to get acquainted with the following:

  • Advanced Imaging Facility: operation of widefield, confocal, two-photon, light-sheet and OPT microscopes,
    and with image analysis techniques using various software tools (eg, FIJI, Imaris, Amira, Huygens)
  • Bioinformatics: population genetics, mammalian genome assembly, immunity genetics and host-pathogen
    co-evolution, and single cell RNA sequencing.
  • Electron microscopy: plastic-based electron microscopy, correlative light and electron microscopy (CLEM)
    and cryo-immobilization methodologies.
  • Flow cytometry and antibodies: Cell sorting & analysis, full spectrum flow cytometry, data analysis, and
    monoclonal antibody production
  • Histopathology: cryotomy, vibrotomy, microtomy, paraffin and resin embedding and sectioning;
    immunostaining and stereology data analysis.

Across all the facilities, there will be the chance for the Fellow to get acquainted with facility operation logistics and financial management in a small international research institute. There will be the opportunity to see the established workflows for facility operation, team management and user management, to explore instrument preventive & corrective maintenance strategies and for the fellow to explore intra-institute collaborations within the greater Lisbon area and broadly in Portugal. The IGC will dedicate supervision capacity for each fellow on secondments.

During secondments, Fellows can stay employed by EMBL.
The IGC intends also to host mini-secondments in a duration of up to two weeks, during which Fellows will have the opportunity to shadow operations at various technical facilities at the IGC, similar, although shorter, to those detailed above.

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