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Genome engineering: CRISPR/Cas in cells and mice – Course and Conference Office

EMBL Course

Genome engineering: CRISPR/Cas in cells and mice

Overview

Course overview

This course will provide training in genome editing and cell engineering in mammalian cells and mouse embryos using the highly efficient CRISPR/Cas9 system. Participants will learn design of CRISPR targets using bioinformatics tools, generation of gene knock-outs/knock-ins, and target validation using the most current technologies. The course will be split into two groups (mammalian cells OR mice) based on participants’ expertise.

Please note that all participants are expected to engage in all sessions. Participants should plan for approximately 1 hour extra per day for self paced learning modules.

Audience

This course is aimed at researchers who are familiar with basic molecular and cell biology techniques and who want to learn how to create an engineered mammalian cell line or mouse model using the most recent and advanced CRISPR/Cas9 system. No previous experience in genome editing is required.

Modules/resources

  • How to create a CRISPR/Cas9 experiment using various design tools
  • Transfection optimisation for efficient gene editing
  • Generation of knock-out and knock-in cell lines and mouse embryos
  • Validation of genome-edited cell lines and embryos

Learning outcomes

After this course you should be able to:

  • Design a CRISPR based project using editing tools for your target gene of interest
  • Choose the right format of gene editing tool and delivery strategy for your cell type or embryos
  • Edit, screen and validate the engineered models, embryo manipulation

What past participants say about the course

“The EMBL course about CRISPR applications for genome engineering was an incredible experience. From the quality of the lectures, the availability of the invited speakers to respond to all questions and doubts, the openness and diversity of participants to the great organization and the impressive facilities and core facility teams working there. It all created a perfect atmosphere for learning about this groundbreaking technique and the inspiring work being done with it as well as great networking. I highly recommend this course.” – Sofia Morazzo, International Clinical Research Center, Czech Republic

The course covers all you need to organise your CRISPR experiments in great detail. The speakers are fantastic and eager to help with your specific questions. The organisation is also fantastic, where you only have to think on CRISPR and nothing else.” – Sergio G. San Miguel, Max Planck Institute for Infection Biology, Germany

Please see EMBL’s COVID-19 safety policy for testing and other requirements to attend this on-site course.

Speakers

Speakers

Adrianna Castillo

EMBL Rome

Italy

Silke Deckert

Thermo Fisher Scientific

Germany

IDT Technologies

Germany

Birgit Koch

Max Planck Institute for Medical Research

Germany

Karl Petri

Universitätsklinikum Würzburg

Germany

Ian Pringle

Thermo Fisher Scientific

United Kingdom

Sandra Stobrawa

Biozol, Calibre Scientific

Germany

Scientific Organisers

Birgit Koch

Max Planck Institute for Medical Research

Germany

Course Organisers

Charlotte Courtney

Course and Conference Officer

EMBL Heidelberg

Germany

Swetlana Krez

Training Laboratory Officer

EMBL Heidelberg

Germany

Programme

Are you on social media? Post using #EMBLCRISPRcas and don’t forget to tag @EMBLEvents.

  • Some pre-course work (such as watching pre-recordings, protocol reading and computational exercises) with estimated time 0-10 hours will be required and will be shared in advance of the course.
  • Some speakers may need to join virtually to give their lecture or Q&A, and the programme is subject to change.
Day 1 – Sunday 1 September 2024
Time (Europe/Berlin)SessionLocation
16:00-16:30Welcome
EMBL housenotes and course overview
ISG Hotel
16:30- 18:00Icebreaker: Flash talks (2 slides, 2 minutes each participant)ISG Hotel
18:00- 19:00(Virtual speaker) Live Keynote Lecture:
Introduction to CRISPR/Cas 9
Dana Carroll – University of Utah, School of Medicine, USA
ISG Hotel
19:00Dinner and Networking at ISG HotelISG Hotel
Day 2 – Monday 2 September 2024
Time (Europe/Berlin)SessionLocation
08:30 – 08:45Bus from ISG Hotel to EMBL
08:45- 09:00Arrival and coffeeCourtyard Room
9:00- 9:15Lab Safety: Swetlana KrezCourtyard Room
09:15-10:15Lecture: Purification of Cas9 protein
Kim Remans- EMBL Heidelberg, Germany
Courtyard Room
10:15-11:15Lecture: CRISPR-Cas genome editing to generate transgenic mice
Neil Humphreys – EMBL Rome, Italy
Courtyard Room
11:15-11:45Coffee breakCourtyard Room
11:45-12:45Everyone:
Practical 1: gRNA design (manual approach)

Kristof Kersse – Thermo Fisher Scientific, Germany
Courtyard Room
12:45-13:45LunchEMBL Canteen
13:45-16:00Everyone:
Practical 1: gRNA design (Basics, Benchling)

Birgit Koch – Max Planck Institute for Medical Research, Germany
Courtyard Room
16:00-16:30Coffee breakCourtyard Room
16:30-17:15Mammalian Cell Group:
Practical 1-1: TrueTag Donor Template Synthesis – PCR

Emmanouela Soura, Thermo Fisher Scientific, UK
Ian Pringle, Thermo Fisher Scientific, UK
Training Lab A
16:30-17:15Short seminar on embryo transfer and demonstration
Neil Humphreys – EMBL Rome, Italy
Michela Ascolani – EMBL Rome, Italy
Maj Simonsen Jackson – EMBL Rome, Italy
Isabel Rollan – EMBL Heidelberg, Germany
Frank Diego Montoya Castillo- EMBL Heidelberg, Germany
Training Lab B
17:15-18:30CRISPR/Cas in different organisms
Tips, pitfalls and trouble shooting

Alexandre Paix – Max Planck Institute for Biology Tübingen, Germany
Courtyard Room
18:30- 19:30Dinner EMBL Canteen
19:30 – 20:30Practical 1.2:
Mammalian Cell Group: TrueTag Donor Template Synthesis – Gel analysis and Clean-up

Emmanouela Soura, Thermo Fisher Scientific, UK
Ian Pringle, Thermo Fisher Scientific, UK
Training Lab A
19:30-20:30Glass transfer pipet prep, harvest embryos, Intro to TLR2 system & describe injection mix prep
Neil Humphreys – EMBL Rome, Italy
Michela Ascolani – EMBL Rome, Italy
Maj Simonsen Jackson – EMBL Rome, Italy
Isabel Rollan – EMBL Heidelberg, Germany
Frank Diego Montoya Castillo- EMBL Heidelberg, Germany
Training Lab B
20:30Bus from EMBL to ISG Hotel
Day 3 – Tuesday 3 September 2024
Time (Europe/Berlin)SessionLocation
08:30 – 08:45Bus from ISG Hotel to EMBL
08:45- 08:55Arrival and coffeeCourtyard Room
08:55- 09:00Overview of the dayCourtyard Room
9:00- 10:00Lecture: A rationale for efficient genome editing using linear repair donors
Alexandre Paix – Max Planck Institute for Biology Tübingen, Germany
Courtyard Room
10:00-11:00Practical lecture: Generation and validation of endogenously tagged cell line
Birgit Koch – Max Planck Institute for Medical Research, Germany
Courtyard Room
10:00-11:00Practical: AAV infection
Maj Simonsen Jackson – EMBL Rome, Italy
Michela Ascolani – EMBL Rome, Italy
Neil Humphreys – EMBL Rome, Italy
Training Lab B
11:00-12:45Practical:
Group A: Transfection of endogenously tagged cell line: duplex formation, formation of RNP and transfection with CRISPR

Birgit Koch – Max Planck Institute for Medical Research, Germany

Group B: True Design Tool and example exercises
Kristof Kersse Thermo Fisher Scientific, Germany
Cell culture
11:00-12:45Practical 1.2: 1st Microinjection, electroporation

Electroporation:
Maj Simonsen Jackson – EMBL Rome, Italy
Michela Ascolani – EMBL Rome, Italy

Microinjection:
Neil Humphreys – EMBL Rome, Italy
Isabel Rollan – EMBL Heidelberg, Germany
Frank Diego Montoya Castillo- EMBL Heidelberg, Germany
Sandra Stobrawa – Biozol/Calibre Scientific
Training Lab B
LAR
12:45-13:45LunchEMBL Canteen
13:45-15:30Practical:
Group A: True Design Tool and example exercises

Kristof Kersse – Thermo Fisher Scientific, Germany

Group B: Transfection of endogenously tagged cell line: duplex formation, formation of RNP and transfection with CRISPR
Birgit Koch – Max Planck Institute for Medical Research, Germany
Courtyard Room+
Cell culture
13:45-15:30Mouse Embryo Group:
2nd Microinjection, electroporation and AAV


Electroporation:
Maj Simonsen Jackson – EMBL Rome, Italy
Michela Ascolani – EMBL Rome, Italy

Microinjection:
Neil Humphreys – EMBL Rome, Italy
Isabel Rollan – EMBL Heidelberg, Germany
Frank Diego Montoya Castillo- EMBL Heidelberg, Germany
Sandra Stobrawa – Biozol/Calibre Scientific
Training Lab B
LAR
15:30- 16:00Coffee breakCourtyard Room
16:00 – 18:00Practical 2 +3:
Mammalian Cell Group
Group A: gRNA efficiency: Lipid transfection of 293FT cells with gRNA and Cas9 protein,
Lipid transfection of 293FT-eBFP cells with gRNA, Cas9 protein and ssODN

Emmanouela Soura- Thermo Fisher Scientific, UK
Ian Pringle – Thermo Fisher Scientific, UK

Group B: gRNA task
Birgit Koch – Max Planck Institute for Medical Research, Germany
Kristof Kersse – Thermo Fisher Scientific, Germany
Courtyard Room+
Cell culture
16:00 – 18:00Mouse Embryo Group:
3rd Microinjection, electroporation and AAV


Electroporation:
Maj Simonsen Jackson – EMBL Rome, Italy
Michela Ascolani – EMBL Rome, Italy

Microinjection:
Neil Humphreys – EMBL Rome, Italy
Isabel Rollan – EMBL Heidelberg, Germany
Frank Diego Montoya Castillo- EMBL Heidelberg, Germany
Sandra Stobrawa – Biozol/Calibre Scientific
Training Lab B
LAR
18:00- 19:00Dinner EMBL Canteen
19:00- 20:30Practical:
Group A: gRNA task

Birgit Koch – Max Planck Institute for Medical Research, Germany
Kristof Kersse – Thermo Fisher Scientific, Germany

Group B: gRNA efficiency: Lipid transfection of 293FT cells with gRNA and Cas9 protein,
Lipid transfection of 293FT-eBFP cells with gRNA, Cas9 protein and ssODN
Emmanouela Soura – Thermo Fisher Scientific, UK
Ian Pringle – Thermo Fisher Scientific, UK
Cell culture
19:00- 20:30Practical 2+3
Mouse Embryo Group
Extra time with Embryos microinjection and embryos transfer KSOM media
O/N culture Student lead requests for extra training.

All trainers
Training Lab B
20:30Bus from EMBL to ISG Hotel
Day 4 – Wednesday 4 September 2024
Time (Europe/Berlin)SessionLocation
08:30 – 08:45Bus from ISG Hotel to EMBL
08:45- 08:55Arrival and coffeeCourtyard Room
08:55- 09:00Overview of the dayCourtyard Room
09:00 – 10:00Lecture: Gene editing in different experimental models
Antony Adamson – The University of Manchester, UK
Courtyard Room
10:00-11:00Practical: Harvest cells and prepare for FACS analysis
Birgit Koch – Max Planck Institute for Medical Research, Germany
Cell culture
10:00 – 11:00Practical 4: Assess and clean-up 2 cell microinjected embryos
Maj Simonsen Jackson – EMBL Rome, Italy
Isabel Rollan – EMBL Heidelberg, Germany
Frank Diego Montoya Castillo- EMBL Heidelberg, Germany
Training Lab B
11:00-11:30Coffee breakCourtyard Room
11:30 – 12:30Lecture: Safety-validating and improving CRISPR 2.0 to enhance immune cell therapies
Karl Petri – Universitätsklinikum Würzburg, Germany
Courtyard Room
12:30 – 13:30LunchEMBL Canteen
13:45 – 15:45Practical 1-3 + 4: Mammalian Cell Group:
Group A: Tag Knock-in: Electroporation of 293FT with gRNA, Cas9 protein and TrueTag donor template

Emmanouela Soura- Thermo Fisher Scientific, UK
Ian Pringle – Thermo Fisher Scientific, UK

Group B: Project discussion
Birgit Koch – Max Planck Institute for Medical Research, Germany
Kristoff Kersse – Thermo Fisher Scientific, Germany
Courtyard Room+
Cell culture
13:45 – 15:45Practical 4: Mouse Embryo Group:
Thaw pre-prepared blastocysts, assess viability, extract DNA. Design and set-up cut test PCR. Prepare agarose gel

Neil Humphreys – EMBL Rome, Italy
Michela Ascolani – EMBL Rome, Italy
Maj Simonsen Jackson – EMBL Rome, Italy
Isabel Rollan – EMBL Heidelberg
Training Lab B
15:45- 16: 15Coffee break
16:15- 18:15Practical 1-3 + 4: Mammalian Cell Group:
Group A: Project discussion

Birgit Koch – Max Planck Institute for Medical Research, Germany
Kristof Kersse – Thermo Fisher Scientific, Germany

Group B: Tag Knock-in: Electroporation of 293FT with gRNA, Cas9 protein and TrueTag donor template
Emmanouela Soura- Thermo Fisher Scientific, UK
Ian Pringle – Thermo Fisher Scientific, UK
Courtyard Room+
Cell culture
16:15- 18:15Practical 5: Mouse Embryo Group: Set up T7 assay and mutant-specific PCRs.
Run O/N (project discussion)

Neil Humphreys – EMBL Rome, Italy
Michela Ascolani – EMBL Rome, Italy
Maj Simonsen Jackson – EMBL Rome, Italy
Training Lab B
18:15- 20:30Pizza Dinner and
Discussion round and drinks: Ethical issues of CRISPR technology and genome engineering

Lead: Antony Adamson – The University of Manchester, UK
ATC Rooftop lounge
20:30Bus to ISG Hotel
Day 5 – Thursday 5 September 2024
Time (Europe/Berlin)SessionLocation
08:30 – 08:45Bus from ISG Hotel to EMBL
08:45- 08:55Arrival and coffeeCourtyard Room
08:55- 09:00Overview of the dayCourtyard Room
09:00 – 10:00Lecture: Imaged-based high-throughput screening RNAi vs CRISPR
Beate Neumann – EMBL Heidelberg, Germany
Courtyard Room
10:00- 11:45Practical in Groups:
Practicals 5-1 & 5-2:Mammalian Cell Group:
GCD Cell Harvest and lysis, set up GCD PCR

Emmanouela Soura- Thermo Fisher Scientific, UK
Ian Pringle – Thermo Fisher Scientific, UK
Cell culture+
Training Lab A
10:00-11:45Mouse Embryo Group: Practicals 5-1 & 5-2
Assess and clean-up 4 to 8 cell embryos.
Run Gels for PCRs. Analyze results. Cut out gel and submit for Sanger sequencing

Neil Humphreys – EMBL Rome, Italy
Michela Ascolani – EMBL Rome, Italy
Maj Simonsen Jackson – EMBL Rome, Italy
Isabel Rollan – EMBL Heidelberg, Germany
Training Lab B
11:45-12:15Group PhotoTBC
12:15-13:15LunchEMBL Canteen
13:15- 14:15Lecture: The 3Cs technology for CRISPR gRNA library generation
Manuel Kaulich – Goethe University, Germany
Courtyard Room
14:15 – 16:30Practical in Groups:
Practical 5.3: Mammalian Cell Group:
PCR analysis, set up GCD re-annealing reaction
Practical 5.4 & 5.5
Set up digestion for GCD, gel purification & sample submission for sanger sequencing
Gel analysis of GCD

Emmanouela Soura – Thermo Fisher Scientific, UK
Ian Pringle – Thermo Fisher Scientific, UK
Training Lab A
14:15 – 16:30Mouse Embryo Group:
Project discussion, focus on the analysis of sequencing data and design options

Neil Humphreys – EMBL Rome, Italy
Michela Ascolani – EMBL Rome, Italy
Isabel Rollan – EMBL Heidelberg, Germany
Antony Adamson – The University of Manchester, UK
Training Lab B
16:30- 17:00Coffee breakCourtyard Room
17:00- 18:00Lecture: Pooled genome-wide CRISPR screens in single cells
Daniel Schraivogel – EMBL Heidelberg, Germany
Courtyard Room
18:15Bus departure to ISG Hotel
19:00Bus from ISG Hotel to Dinner downtown
19:30Downtown dinnerZum Roten Ochsen
Day 6 – Friday 6 September 2024
Time (Europe/Berlin)SessionLocation
08:30 – 08:45Bus from ISG Hotel to EMBLCourtyard Room
08:45- 08:55Arrival and coffeeCourtyard Room
08:55- 09:00Overview of the dayCourtyard Room
9:00 – 10:30Technology Lounge: Genome modification technologies
Presentation by different companies
Thermo Fisher Scientific
New England Biolabs (Karl von Laer)
Integrated DNA Technologies (Marc Bleischwitz and K.Julia Duda)
Courtyard Room
10:30-12:30
Practical in Groups:
Mammalian Cell Group:
Group A: Examine BFP cells and TrueTag Knock-in via microscopy and FACS

Emmanouela Soura – Thermo Fisher Scientific, UK
Ian Pringle – Thermo Fisher Scientific, UK

Group B: Knock-In cell validation – DNA Preparation and set up of PCR at the end of session
Birgit Koch – Max Planck Institute for Medical Research, Germany

Change Groups after 60 min

with concurrent coffee break
Training Lab A
10:30-11:30Mouse Embryo Group: Thaw TLR2 embryos and examine KO and KI morular/ blastocysts for florescence, Knock-In validation.
Neil Humphreys – EMBL Rome, Italy
Michela Ascolani – EMBL Rome, Italy
Maj Simonsen Jackson – EMBL Rome, Italy
Isabel Rollan – EMBL Heidelberg, Germany
Training Lab B
11:30-12:305 participants: Image embryos (ALMF)
5 participants: Project discussion

Neil Humphreys – EMBL Rome, Italy
Michela Ascolani – EMBL Rome, Italy
Maj Simonsen Jackson – EMBL Rome, Italy
Isabel Rollan – EMBL Heidelberg, Germany
Beate Neumann – EMBL Heidelberg, Germany
ALMF
Courtyard Room
12:30-13:30LunchEMBL Canteen
13:30-15:45
Mammalian Cell Group:
Knock-In cell validation – Gel, gel analysis
Birgit Koch – Max Planck Institute for Medical Research, Germany

with IC tour (or other tour)
Training Lab A
13:30-14:305 participants: Image embryos (ALMF)
5 participants: Project discussion

Neil Humphreys – EMBL Rome, Italy
Michela Ascolani – EMBL Rome, Italy
Maj Simonsen Jackson – EMBL Rome, Italy
Isabel Rollan – EMBL Heidelberg, Germany
Beate Neumann – EMBL Heidelberg, Germany
ALMF
Courtyard Room
14:30-15:45Mouse embryo group:
Tour of LAR Facility

Ernesto de la Cueva Bueno – EMBL Heidelberg
LAR
15:45-16:15Solutions room and final wordsCourtyard Room
16:30Bus shuttle downtown and central station

Practical information

Registration fees and motivation letter

The course is limited to 20 participants. For selection purposes, please note that your application will not be considered without a letter of motivation.

Registration

Registration fees include admission, course materials, meals and coffee breaks. Participants are expected to book and pay their own accommodation and travel expenses. 

Academia€815
PhD Student€815
Industry€1325

A letter to support your visa application will be issued, on request, once payment of the registration fee is confirmed. We recommend that you book your visa appointment as soon as possible, to avoid any delay with your visa application.

Confirmation and payment

The registration fee should be paid only after acceptance to the course. The results will be announced approximately 2-3 weeks after the application deadline.

Motivation letter submission

After you have logged in and successfully registered, you will receive an email asking you to submit your motivation letter. Click on the link provided and enter your motivation letter in the text box provided. Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering.

Instructions

  1. Include your relevant skills, experience and qualifications showing why you would be suitable for the course.
  2. Explain why you would like to attend, including what you can contribute and how you think you will benefit from the course.

Please note:

  • The limit of 2000 characters refers to manually typed text and excludes spaces. If an error occurs try using a different web browser (preferably Google Chrome or Mozilla Firefox).
  • If you copy-paste the text into the form, hidden formatting might still be included which may cause the text to exceed the 2,000 character limit resulting in an error message. We recommend you clear all formatting before pasting in the text.
  • If you have special symbols in your text, make sure you are using Unicode characters, otherwise these will not be recognised.

For detailed instructions, please watch our video on how to submit a course motivation letter.

Further details

For further information about registration and motivation letter submission please refer to the FAQ page.

Financial assistance

Financial assistance

Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers, travel grants and childcare grants

Your place in the meeting is only confirmed by paying the registration fee, which is mandatory even when receiving a fee waiver.

Registration fee waiver

The fee waiver will cover the registration sum that you have paid to attend the course.

Travel grant

The travel grant will cover the cost of travel (airfare, train, bus, taxi, accommodation, visa, and/or registration fees*) and is provided up to specified caps which are normally as follows:

– up to €400 for participants travelling to an EMBL Course within Europe.

– up to €1000 for participants travelling to an EMBL Course from outside Europe.

– up to €500 for any participant travelling to an EMBO Practical Course.

– up to €1000 for any participant working in Chile, India, Singapore or Taiwan travelling to an EMBO Practical Course.

– up to €700 for any participant working in Croatia, Czech Republic, Estonia, Greece, Hungary, Italy, Lithuania, Luxembourg, Poland, Slovenia, and Turkey travelling to an EMBO Practical Course.

*Registration fees are only covered for EMBO Practical Courses

The organisers may reduce the grant cap to accommodate more participants. Recipients will be notified of their travel cap amount when they are informed of the outcome of their application. Original receipts must be provided with your signature for all costs incurred within two months of completion of travel. Scanned copies cannot be accepted.

Childcare grant

There is the possibility to apply for a childcare grant to offset child care costs incurred by participants, speakers, trainers and organisers when attending a course. Eligible costs include (but are not limited to) fees for a babysitter or child-care facility and travel costs for a caregiver. Please note that priority will be given to early-stage researchers. There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants.

Boehringer Ingelheim Fonds travel grant

Applies to selected courses only. Availability will be indicated during the motivation letter submission process.

This grant covers costs related to your attendance at the course (registration, travel and accommodation costs). The grant is restricted to PhD students and postdocs who conduct basic biomedical research.

Whether you are eligible to apply for a travel grant, depends on when you received your university entrance qualification (e.g. Abitur, A-Levels, High School Diploma, Final State Examination):

– for PhD and MD students, as well as graduates, the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course

– for postdocs, the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course

Application

You may apply for financial assistance when submitting your motivation letter for courses. In your application, you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career. Application for financial support will not affect the outcome of your registration application.

For the Boehringer Ingelheim Fonds Travel Grant, there is a pre-application question during the motivation letter submission process, and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation.

Selection

The scientific organisers will select the recipients of registration fee waivers and travel grants during the motivation letter or abstract selection process. Results will be announced approximately 6 – 8 weeks before the event start date, however for some events this may be delayed. Selection results do not impact your admission to the meeting. Selection for registration fee waivers and travel grants is based on scientific merit, your current work or study location, the reasons for needing financial support, and the impact this event will have on your career.

Childcare grants will be allocated in the same timeframe (6-8 weeks before the event start date). Please note that priority will be given to early-stage researchers.

Reimbursement

Costs will be reimbursed after the meeting only once a reimbursement form and original receipts (from travel costs) have been received.

Further details

See our list of external funding opportunities and for further information about financial assistance please refer to the FAQ page.

Accommodation and travel

Hotel

Accommodation is not included in the registration fee. Participants are expected to book and pay for their own accommodation. A mix of single and twin rooms have been reserved for 6 nights from Saturday 31 August 2024 – Friday 6 September 2024 at the ISG Hotel.  Single rooms are limited and will be available on a first come, first served basis. After the selection process, selected participants should contact the hotel directly to make a booking with a booking code (code of your course e.g. GEE24-01) by the deadline of Monday 5 August 2024. We recommend that all course participants stay in the dedicated hotel for the course.

Travel information

For travel information, please see here.

If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn ‘Event Ticket’ (called the ‘Veranstaltungsticket’ in German). This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km. You need to provide proof of your event attendance when purchasing the ticket.

For more information in English see here or in German see here.

You can book your ticket here.

Local transport

Shuttle buses will go from the ISG Hotel to EMBL and back, mornings and evenings. A bus schedule and location of the bus stops will be made available prior to the meeting.

Further details

Address: EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany

For more information about accommodation and travel, please refer to the FAQ page.

On-site information

Catering

All meals and coffee breaks are included in the registration fee. Our catering staff will prepare a wide variety of vegetarian meals, meat and fish dishes, soups, pasta, fresh fruit and vegetables, as well as a variety of desserts.

Please wear your badge at all times when serving yourself.

No food or drinks are allowed in the laboratories.

Electricity and charging station

In most places the electricity is 220 volts AC (50 cycles). An adaptor and a plug that fits the German socket may be needed for your appliances/laptop (i.e. American, Japanese, etc.). A USB charging station for electronic devices is available at the registration desk.

EMBL Merchandise

If you are interested in purchasing EMBL merchandise (products presented in the glass display in the registration area), please email the EMBL shop to place an order or get in contact with your Course Organiser.

Kindly note the EMBL shop is only open upon request and all purchases must be made in cash (Euros only).

Health and safety notes

Please read EMBL’s COVID-19 safety policy for on-site events.
Do not smoke in any EMBL building.
Eating and drinking is prohibited in all laboratories.
Do not enter any restricted areas or the laboratories unless instructed to do so.

If first aid is required …

  • The first aid room is located next to the ATC Registration Desk (room 10- 205).
  • Dial the Emergency number 222 from any EMBL internal phone only.
  • Where is the accident? What happened? How many injured?
  • Emergency number 06221-387 7821 from mobile phones.
  • Please report all accidents to the conference officer at the registration desk.

In case of fire …

  • Press the nearest fire alarm button or the Emergency number 222 from any internal phone.
  • A loud fire alarm will go off if an evacuation is required. On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points
  • Do not use the lifts.

Beyond first aid…

Please remember to bring your own medication, if needed, to the conference. Note that the next pharmacy is a 4-minute drive from the EMBL, but for many medications you will be required to see a doctor to get a prescription.

Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg. In any case, the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary.

Internet

Wi-Fi is available on campus. Log in using the EMBL-Events network and the event specific password, which will be provided on site. The eduroam network (secure, worldwide roaming access service developed for the international research and education community) is also available.

Lost and found

‘’Lost and Found’’ items are kept at the registration desk until the end of the conference.

Luggage

There are lockers available on-site to store your luggage, which require a 2 EURO coin to operate. There is another luggage room on level E0, which is free to use but remains unlocked during the conference.

Nursing room

There is a nursing room available in the ATC Rooftop Lounge on level A29.

Photography

During the conference, an EMBL Photographer may be taking photos. If you would not like to appear in these, please inform the photographer or a member of the Course and Conference Office.

Printing

We can help to print your boarding pass/train ticket. Please send it to events@embl.de and collect your print-outs at the registration desk.

Room for prayer, yoga, and meditation

There is a room for prayer, meditation, and yoga located on level E0 behind the Auditorium. Please be respectful of others using the room.

Sightseeing

A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing.

Travel to and from the venue

During the event, we provide conference shuttle buses to and from EMBL. In addition, there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time. Information on the shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page.

Additional information

Address: EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany

Please find additional information including FAQs, terms and conditions, COVID-19 safety policy and travelling to EMBL on our Information for Participants page.

Event software

Event software

The EMBL eCampus learning platform will be used to collaborate, communicate and network with all of the course participants. All participants will receive information on how to join shortly before the course. We recommend using Chrome, Safari or Mozilla Firefox browsers for eCampus. 

Additional information

Please find additional information including FAQs, terms and conditions, COVID-19 safety policy and travelling to EMBL on our Information for Participants page.

COVID-19 related questions

COVID-19 information for on-site events at EMBL Heidelberg can be found in our COVID-19 FAQs.

Sponsors

Event Partner

Event Sponsor

Event supporter

Sponsorship opportunities

We offer a variety of event sponsoring possibilities, with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget. Discounts are available for companies sponsoring multiple events at EMBL Heidelberg. View other events, or contact sponsorship@embl.de for further information.

If you are interested in becoming a media partner of this event, please visit our media partnerships webpage.

Warning

EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials. One current scam campaign of which we are aware is conducted using the name ‘Judy Eastman’ (judy@gopcontact.a2hosted.com) and entails approaches to sponsors offering sponsorship opportunities on EMBL’s behalf. Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences, symposia and courses is handled by EMBL directly and is sent from an official EMBL account. EMBL does not work with any external providers on sponsorship acquisition.

Please also note that:

  • EMBL never provides attendee lists for purchase. Any offers of such are fraudulent.
  • EMBL will never call or email you to ask for your credit card details or to request a payment.
  • All payments are on invoice.

Suspicious communications purportedly from, for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship@embl.de.

Media kit

Want to let others know you’re attending this event? Take a look at our shareable media and feel free to use them in your social media channels or presentations.

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Date: 1 - 6 Sep 2024

Location: EMBL Heidelberg

Venue: EMBL Advanced Training Centre


Deadline(s):

Application: Closed


Organisers:

  • Neil Humphreys
    EMBL Rome, Italy
    • Kristof Kersse
      Thermo Fisher Scientific, Germany

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