The neurovascular interface

Time (Europe/Berlin)	Speaker
12:00-13:30	Registration and light refreshments
13:30-13:40	Opening remarks
13:40-15:25	Session 1 – Neurovascular signaling Chair: Amparo Acker-Palmer – Goethe University Frankfurt am Main, Germany
13:40-14:10	Molecular regulation of blood brain barrier function Anne Eichmann – Yale School of Medicine, USA Not available on demand
14:10-14:25	Short talk: Foxf2 maintains brain endothelial cell function via Tie2 signaling Martin Dichgans – Ludwig Maximilians University of Munich, Germany Not available on demand
14:25-14:40	Short talk: Vascular guidance configures barrier mesenchymal compartments in the regenerating nerve Ganesh Parameshwar Bhat – San Raffaele Scientific Institute, Italy
14:40-14:55	Short talk: Understanding brain vascular responses to insulin Nicole Sumargo – University of Tasmania, Australia
14:55-15:25	Function of neuro-vascular interactions in organ development Yoh-suke Mukouyama – National Heart, Lung, and Blood Institute, USA Not available on demand
15:25-16:00	Coffee break
16:00-17:45	Session 1 – Neurovascular signaling (continued) Chair: Anne Eichmann – Yale School of Medicine, USA
16:00-16:30	Cellular and molecular mechanisms controlling artery formation in the CNS Ralf H. Adams – Max Planck Institute for Molecular Biomedicine, Germany
16:30-16:45	Short talk: Involvement of JAM-C in the interaction between glioblastoma stem-like cells and brain endothelial cells Sara Rosinska – University of Nantes, France
16:45-17:00	Short talk: Premature vascularization of motor neuron columns results in aberrant motor neuron development Ricardo Vieira – Heidelberg University, Germany
17:00-17:15	Short talk: Tanycytic VEGF receptor signaling in the blood-hypothalamus barrier: a new player in the communication between the brain and the periphery Ines Martinez-Corral – National Institute for Health and Medical Research (Inserm), France Not available on demand
17:15-17:45	Brain and retina vascularisation in health and disease Christiana Ruhrberg – University College London, United Kingdom Not available on demand
17:45-19:30	Poster session 1 (odd numbers) Poster numbers
19:30-21:00	Dinner
21:00-22:00	After dinner drinks with live music

Time (Europe/Berlin)	Speaker
09:15-10:45	Session 2 – Brain lymphatics Chair: Gou Young Koh – Institute for Basic Science, Republic of Korea
09:15-09:45	Virtual talk: Neuro-immune events at the brain barriers Elga de Vries – Amsterdam UMC, The Netherlands Not available on demand
09:45-10:00	Short talk: Anatomical diversity of lyve-1 perivascular macrophages distribution in the mouse brain Guy Malkinson – Collège de France, France
10:00-10:15	Short talk: Postnatal development of the neurovascular unit is impaired in Megalencephalic leukoencephalopathy with subcortical cysts Martine Cohen-Salmon – Collège de France, France
10:15-10:45	Towards manipulation of brain lymphatic drainage pathways in CNS disease Kari Alitalo – University of Helsinki, Finland Not available on demand
10:45-11:15	Coffee break
11:15-12:30	Session 2 – Brain lymphatics (continued) Chair: Kari Alitalo – University of Helsinki, Finland
11:15-11:45	Defining vascular heterogeneity at CNS borders Gou Young Koh – Center for Vascular Research, South Korea
11:45-12:00	Short talk: Blood-brain barrier endothelial A20 protects from autoimmune neuroinflammation: a novel role for A20-regulated endothelial Icosl in immune cell trafficking Lisa Johann – Johannes Gutenberg University Mainz, Germany
12:00-12:30	Choroid plexus regulation of adult neural stem cells Fiona Doetsch – University of Basel, Switzerland Not available on demand
12:30-14:00	Lunch and Meet the speakers with: Anne Eichmann, Yoh-suke Mukouyama, Ralf H. Adams, Christiana Ruhrberg, Kari Alitalo, Gou Young Koh, Fiona Doetsch, David Attwell, Serge Charpak, and Andy Shih
14:00-15:30	Session 3 – Neurovascular coupling Chair: David Kleinfeld – University of California, San Diego, USA
14:00-14:30	Immune cell influences on the cerebral microvasculature in Alzheimer’s disease David Attwell – University College London, UK
14:30-14:45	Short talk: Bidirectional control of neurovascular coupling by pyramidal neurons Bruno Cauli – Institute of Biology Paris-Seine, France
14:45-15:00	Short talk: Engineering approaches to investigate the biophysical role of extracellular matrix in the neurovascular interface Nicholas Kurniawan – Eindhoven University of Technology, The Netherlands
15:00-15:30	The dynamic of brain oxygenation during neurovascular coupling Serge Charpak – The Vision Institute, France Not available on demand
15:30-16:00	Coffee break
16:00-17:45	Session 3 – Neurovascular coupling (continued) Chair: David Attwell – University College London, UK
16:00-16:30	Optical dissection of brain capillary function Andy Shih – Seattle Children’s Hospital, USA
16:30-16:45	Short talk: Cerebrovascular reactivity to hypercapnia and neurovascular coupling explore different vascular beds Marine Tournissac – The Vision Institute, France Not available on demand
16:45-17:00	Short talk: Regulation of blood flow patterns by oxytocin neurons through specialized neurovascular coupling dynamics Preethi Rajamannar – Weizmann Institute of Science, Israel
17:00-17:15	Short talk: An atlas of the post-natal cerebral vasculature Nicolas Renier – Paris Brain Institute, France
17:15-17:45	Competing forces shape the spatial pattern of pial vasomotor oscillations across cortex David Kleinfeld – University of California, San Diego, USA Not available on demand
18:00	Free evening
18:30-20:00	Optional: Heidelberg Old Town tour with an English speaking tour guide (registration required)

Time (Europe/Berlin)	Speaker
09:15-10:45	Session 4 – Blood-brain barrier Chair: Chenghua Gu – Harvard Medical School, USA
09:15-09:45	Vascular instructions on neuronal development Amparo Acker-Palmer – Goethe University Frankfurt am Main, Germany Not available on demand
09:45-10:00	Short talk: Development of the intra-neural vascularization and physio-pathological role of the blood-nerve barrier Isabelle Brunet – Collège de France, France Not available on demand
10:00-10:15	Short talk: Generating new in vitro 3D blood-brain barrier models to better understand cerebral malaria Maria Bernabeu – EMBL Barcelona, Spain
10:15-10:45	How does the blood-brain barrier regulate brain function and behavior? Richard Daneman – University of California, San Diego, USA Not available on demand
10:45-11:15	Coffee break
11:15-12:30	Session 4 – Blood-brain barrier (continued) Chair: Richard Daneman – University of California, San Diego, USA
11:15-11:45	Molecular mechanisms governing the blood brain barrier function Chenghua Gu – Harvard Medical School, USA
11:45-12:00	Short talk: Optimizing next-generation brain delivery platforms with in vitro blood-brain barrier models Roberto Villasenor Solorio – Roche Innovation Center, Switzerland
12:00-12:30	Mechanisms of neurovascular Wnt signaling Benoit Vanhollebeke – University of Brussels, Belgium Not available on demand
12:30-14:00	Lunch and Meet the speakers with: David Kleinfeld, Amparo Acker-Palmer, Richard Daneman, Chenghua Gu, Benoit Vanhollebeke, Katerina Akassoglou, Anju Vasudevan, Carmen Ruiz de Almodovar, and Ferdinand le Noble
14:00-15:30	Session 5 – Neurovascular pathology Chair: Benoit Vanhollebeke – University of Brussels, Belgium
14:00-14:30	The immunology of blood: unlocking the drivers for neurodegeneration Katerina Akassoglou – University of California, San Francisco, USA Not available on demand
14:30-14:45	Short talk: Exploring the role of FOXF2 in Small vessel disease (SVD) in a novel human iPSC-derived model of the neurovascular unit (NVU) Dominik Paquet – Ludwig Maximilians University of Munich, Germany Not available on demand
14:45-15:00	Short talk: Modeling ischemic stroke in a triculture neurovascular unit on-a-chip Arya Lekshmi Nair – Mimetas / Amsterdam UMC, The Netherlands
15:00-15:30	Virtual talk: Parenchymal Border macrophages regulate CSF flow Jonathan Kipnis – Washington University School of Medicine in St. Louis, USA
15:30-16:00	Coffee break
16:00-17:15	Session 5 – Neurovascular pathology (continued) Chair: Katerina Akassoglou – University of California, San Francisco, USA
16:00-16:30	The vascular origins of mental illness and new treatment strategies Anju Vasudevan – Huntington Medical Research Institutes (HMRI), USA
16:30-16:45	Short talk: Machine learning analysis of whole mouse brain vasculature to study neurovascular diseases Mihail Todorov – Ludwig Maximilians University of Munich, Germany
16:45-17:15	Virtual talk: Glioblastoma invasion: injury and neurodevelopmental programmes converge at the perivascular niche Simona Parrinello – University College London, UK Not available on demand
17:15-19:00	Poster session 2 (even numbers) Poster numbers
19:00-21:00	Conference dinner
21:00-22:30	Social event: science pub quiz

Time (Europe/Berlin)	Speaker
09:15-10:15	Session 6 – Vessel-neuronal structure Chair: Ralf H. Adams – Max Planck Institute for Molecular Biomedicine, Germany
09:15-09:45	Blood vessels and neural cells in the CNS: interactions and molecular crosstalk Carmen Ruiz de Almodovar – University of Bonn, Germany Not available on demand
09:45-10:00	Short talk: Push-pull signals from motor axons direct endothelial remodeling to ensure assembly of neuromuscular connectivity Dario Bonanomi – San Raffaele Scientific Institute, Italy
10:00-10:15	Short talk: Perivascular neurons direct three-dimensional vascular scaffold formation via piezo2-mediated contact Xin Duan – University of California, San Francisco, USA Not available on demand
10:15-10:45	Coffee break
10:45-12:00	Session 6 – Vessel-neuronal structure (continued) Chair: Ralf H. Adams – Max Planck Institute for Molecular Biomedicine, Germany
10:45-11:00	Short talk: Vascular Wnt5A orchestrates cerebellar neuronal architecture and circuitry Marta Parrilla Monge – Goethe University Frankfurt am Main, Germany Not available on demand
11:00-11:15	Short talk: Obesity as new platform to study neurovascular topology Marc Schneeberger Pane – Yale University, USA
11:15-11:45	Organotypical features of spinal cord vascularisation and repair Ferdinand le Noble – Karlsruher Institut für Technologie, Germany Not available on demand
11:45-12:00	Closing remarks and poster prize
12:15	Packed lunch and departure
12:30	Bus to ISG Hotel and hotels downtown
12:45	Optional: Shuttle bus to Frankfurt Airport (Terminal 1) Tickets can be purchased during the conference for 25 EUR with credit card only

Accommodation is not included in the conference registration fee.

As further changes in our events are possible due to COVID-19, you should book flights, trains and hotels with flexible options and favourable cancellation conditions.

The hotels below have rooms on hold for participants until 6 October 2022, in some cases at special rates. Please quote the booking code EES22-11 and confirm the exact price of the room with the hotel directly.

Hotel Anlage	Hotel ibis Heidelberg	Premier Inn Heidelberg City
Hotel Bayrischer Hof	ISG Hotel	Staycity Aparthotel Heidelberg
B&B Hotel	Leonardo Hotel Heidelberg City Centre	Steffi’s Hostel Heidelberg
Exzellenz Hotel & Boarding House	Meininger Heidelberg	Hotel Vier Jahreszeiten Heidelberg
Hotel Holländer Hof	Hotel Monpti

Conference shuttle buses

Conference shuttle buses are free of charge for participants, and depart from designated bus stops near the hotels to EMBL and back, mornings and evenings.

Download the conference bus schedule here.

The bus stops for this conference are:

• Star Inn Hotel (close to B&B Hotel and Main Train Station)
• Kurfürsten-Anlage (close to Main Train Station)
• Leonardo Hotel City Centre (Bergheimer Strasse)
• Neckarmünzplatz
• Peterskirche
• ISG Hotel

View Conference shuttle bus stops and hotels in a larger map. Please note that not every bus stop will be used for every event.

Further details

Address: EMBL, Meyerhofstraße 1, 69117 Heidelberg, Germany. For further information on getting to EMBL Heidelberg visit Public Transportation to the Venue. For information about accommodation and local transportation please refer to the FAQ page.

Catering

All meals and coffee breaks are included in the registration fee. Our catering staff will prepare a wide variety of vegetarian meals, meat and fish dishes, soups, pasta, fresh fruit and vegetables, as well as a variety of desserts.

Please wear your badge at all times when serving yourself.

No food or drinks are allowed in the auditorium.

Charging lockers

There are lockers available next to the stairs leading down into the Auditorium. You will find some of those equipped with sockets to charge your smartphone/tablet etc.

Electricity and charging station

In most places the electricity is 220 volts AC (50 cycles). An adaptor and a plug that fits the German socket may be needed for your appliances/laptop (i.e. American, Japanese, etc.). A USB charging station for electronic devices is available at the registration desk.

EMBL merchandise

EMBL Merchandise is available on Mon – Thu (9 am – 12 pm). If you are interested in purchasing an EMBL souvenir (products presented in the glass display in the registration area), please ask at the registration desk for more information.

Health and safety notes

Please read EMBL’s COVID-19 safety policy for on-site events.
Do not smoke in any EMBL building.
Eating and drinking is prohibited in the Auditorium and all laboratories.
Do not enter any restricted areas or the laboratories unless instructed to do so.

If first aid is required …

• The first aid room is located next to the ATC Registration Desk (room 10- 205).
• Dial the Emergency number 222 from any EMBL internal phone only.
• Where is the accident? What happened? How many injured?
• Emergency number 06221-387 7821 from mobile phones.
• Please report all accidents to the conference officer at the registration desk.

In case of fire …

• Press the nearest fire alarm button or the Emergency number 222 from any internal phone.
• A loud fire alarm will go off if an evacuation is required. On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points
• Do not use the lifts.

Beyond first aid…

Please remember to bring your own medication, if needed, to the conference. Note that the next pharmacy is a 4-minute drive from the EMBL, but for many medications you will be required to see a doctor to get a prescription.

Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg. In any case, the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary.

Internet

Wi-Fi is available everywhere on the premises (no password required), just log on to ATC-Guest. The eduroam network (secure, world-wide roaming access service developed for the international research and education community) is also available.

Lost and found

‘’Lost and Found’’ are kept at the registration desk until the end of the conference.

Luggage

There are lockers available on-site to store your luggage, which require a 2 EURO coin to operate. There is another luggage room on level E0, which is free to use but remains unlocked during the conference.

Nursing room

There is a nursing room available in the ATC Rooftop Lounge on level A29.

Photography

During the conference an EMBL Photographer may be taking photographs. If you would not like to appear in these, please inform the photographer or a member of the Course and Conference Office.

Printing

We can help printing your boarding passes/train ticket. Please send it to events@embl.de and collect your print-outs at the registration desk.

Room for prayer, yoga and meditation

There is a room for prayer, mediation and yoga located on level E0 behind the Auditorium. Please be respectful of other participants using the room.

Sightseeing

A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing.

Travel to and from the venue

During the event we provide conference shuttle buses to and from EMBL. In addition, there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time. Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page.

Useful German expressions

English	German
Hello	Hallo
Goodbye	Auf Wiedersehen
Good morning	Guten Morgen
Good afternoon	Guten Tag
Good evening	Guten Abend
Good night	Gute Nacht
I’m sorry	Tut mir leid
Excuse me…	Entschuldigen Sie
How are you?	Wie geht’s?
I’m fine thanks. And you?	Mir geht es gut , danke, und dir/Ihnen?
What is your name	Wie heisst du? Wie heissen Sie?
My name is	Ich heisse
Do you speak English	Sprechen Sie Englisch?
I don’t understand	Ich verstehe nicht
Please speak more slowly	Können Sie bitte langsamer sprechen
Thank you	Danke schön
Where is the toilet?	Wo ist die Toilette?
Please call me a taxi	Bitte rufen Sie mir ein Taxi
How do I get to….?	Wie komme ich zum/zur…..?
A beer/two beers, please	Ein Bier/zwei Bier bitte
A glass of red/white wine please	Ein Glas Rot/Weisswein bitte
The menu, please	Die Speisekarte, bitte
Is there a local speciality?	Gibt es eine Spezialität aus dieser Gegend?
I’m Vegetarian	Ich bin Vegetarier
It was delicious	Es war hervorragend
The bill, please	Die Rechnung, bitte
I have a headache	Ich habe Kopfschmerzen
I have a sore throat	Ich habe Halsschmerzen
My stomach hurts	Ich habe Magenschmerzen
I’m allergic to	Ich bin allergisch gegen
I need a doctor who speaks English	Gibt es einen Arzt, der Englisch spricht?

What’s included?

• Access to all the livestreamed talks
• Video library of the recorded talks during and after the event
• Facility to submit questions

Please note that only on-site participants are able to submit abstracts and participate in the poster sessions.

Event platform

We are using an event platform for this conference. More information about the platform will be shared ahead of the conference.

Guidelines

• Do not broadcast the conference to unregistered participants.
• You are encouraged to tweet and post about the event. Tweet unless the speaker specifically says otherwise, but be mindful of unpublished data. 
• Please do not capture, transmit or redistribute data presented at the meeting.

Additional information can be found in our Code of Conduct.

Health and well-being

It is important to stay healthy and move around, especially when you are attending an event virtually. We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event.

How to ask questions

Please use the Q&A function in the event platform.

If you have any other questions, you can go to the Help Desk in the event platform. Click on ‘more’ on the top menu and click Help Desk. 

Time zone

The programme is planned based on the Europe/Berlin time zone, unless otherwise stated. Please take your time zone into consideration when planning your attendance.

Please find additional information including FAQs, terms and conditions, COVID-19 safety policy and travelling to EMBL on our Information for Participants page.

COVID-19 information for on-site events at EMBL Heidelberg can be found in our COVID-19 FAQs.