Christine Mummery
Leiden University Medical Center
The Netherlands
EMBO Workshop
This conference will take place at EMBL Heidelberg, with the option to attend virtually.
The cardiovascular system is a multicellular and disseminated organ consisting of the heart, a network of vessels and circulating blood, thereby forming an intricately interdependent system, whose dysfunction is the leading cause of human mortality. Despite translational progress with impactful new interventional and pharmacological therapies, cardiovascular dysfunction continues to plague mankind.
The current therapeutic approaches are either organ-centric or tackle the consequences of end-stage cardiovascular disease (CVD). New basic research approaches are focused on a deeper understanding of the causes and early development of CVD to identify mechanisms close to the root of the disease, providing the promise to prevent, halt, and reverse the disease process. In parallel, new tissue engineering and mechanobiology approaches are revolutionizing cardiovascular discovery research and disease modeling by more closely mimicking the human situation. However, these are largely separated research communities, with yet little crosstalk or exchange between the two. This new EMBO Workshop aims to transform the established organ-centric view on single cardiovascular organs into a systems biomedicine approach by tearing down the walls between disciplines and moving on to discussion of the cardiovascular system with an inter-, trans-, and cross-disciplinary approach.
Leiden University Medical Center
The Netherlands
Southwestern Medical Center at Dallas
USA
Brown University
USA
Tufts University School of Medicine
USA
Heidelberg University & DKFZ Heidelberg
Germany
University of Turin
Italy
University of Washington Seattle
USA
Heidelberg University
Germany
Heidelberg University
Germany
Max Delbrück Center
Germany
EMBL Barcelona
Spain
Amsterdam UMC
The Netherlands
University of Sao Paulo Medical School
Brazil
University of Colorado Anschutz Medical Campus
USA
Institute of Molecular Biotechnology Vienna
Austria
Toronto General Hospital Research Institute
Canada
Murdoch Children’s Research Institute Melbourne
Australia
Åbo Akademi University and Eindhoven University of Technology
Finland
EMBL Heidelberg
Germany
Hubrecht Institute
The Netherlands
Tufts University School of Medicine
USA
Heidelberg University
Germany
EMBL Barcelona
Spain
Are you on social media? Post using #EMBOCardioBiology and don’t forget to tag @EMBLEvents
Time (Europe/Berlin) | Session |
---|---|
11:15 – 13:15 | Registration and light refreshments |
11:45 – 12:45 | Industry workshop “Suction-assisted Imaging Window for Stabilized Intravital Imaging of Lung and Heart in a Live Animal” by IVIM Technology (registration required) |
13:15 – 13:30 | Opening remarks |
13:30 – 14:30 | Keynote: Cardiovascular diseases and drugs: where are we with hiPSC models? Christine Mummery – Leiden University Medical Center, The Netherlands |
14:30 – 17:00 | Session 1: Where developmental biology meets cardiovascular engineering (Chair Johannes Backs) |
14:30 – 15:00 | Genome editing to understand and engineer heart development Alessandro Bertero – University of Turin, Italy |
15:00 – 15:15 | A modified mRNA encoding Myc and Cyclin T1 improves cardiac function after myocardial injury in the mouse Catherine Wilson – University of Cambridge, United Kingdom |
15:15 – 15:45 | Coffee break and meet the speakers |
15:45 – 16:00 | Scaffold moulding for a heterotypic mini-heart Juan Antonio Guadix Dominguez – University of Málaga, Spain |
16:00 – 16:30 | Genetic and epigenetic regulation of cardiovascular development and disease Gergana Dobreva – Heidelberg University, Germany Not available on demand |
16:30 – 16:45 | Modeling diastolic dysfunction in a human heart-on-a-chip platform Omar Mourad – University of Toronto, Canada |
16:45 – 17:00 | Epicardioids as a novel tool to study human heart development and disease Tatjana Dorn – Klinikum Rechts der Isar, Technical University of Munich, Germany |
17:00 – 17:30 | Cardioids unravel human heart development and disease Sasha Mendjan – Institute of Molecular Biotechnology Vienna, Austria |
17:30 – 18:30 | Speed networking |
18:30 – 20:00 | Dinner in Canteen |
20:00 – 21:30 | After dinner drinks – ATC Foyer |
Time (Europe/Berlin) | Session |
---|---|
09:00 – 12:00 | Session 2: Where engineering meets cardiovascular regeneration (Chair Jennifer Davis) |
09:00 – 09:30 | Vascularization strategies for cardiac regeneration Sara Nunes Vasconcelos – Toronto General Hospital Research Institute, Canada |
09:30 – 10:00 | Targeting arrhythmia in hiPSC-CMs and fibrosis in cardiac tissue culture José E. Krieger – University of Sao Paulo Medical School, Brazil |
10:00 – 10:15 | Species-matched cell therapy augments primary remuscularization to regenerate the chronically infarcted heart Lay Ping Ong – University of Cambridge, United Kingdom Not available on demand |
10:15 – 10:30 | NAD+ controls circadian rhythmicity during cardiac aging Pieterjan Dierickx – Max Planck Institute for Heart and Lung Research, Germany |
10:30 – 11:00 | Coffee break and meet the speakers |
11:00 – 11:30 | Bioprinting cardiac tissue in vitro and in vivo: Where are we at? Daniela Duarte Campos – Heidelberg University, Germany |
11:30 – 12:00 | Maturing the heart: implications for disease modelling, drug discovery & regenerative medicine Enzo Porrello – Murdoch Children’s Research Institute Melbourne, Australia Not available on demand |
12:00 – 13:30 | Lunch |
12:40 – 13:30 | Meet the editors Moderator: Pilar Alcaide Editors: Yevgeniya Nusinovich (Science) & Lise Roth (EMBO Molecular Medicine) |
13:30 – 16:00 | Session 3: Where cardiomyocyte biology meets immunology (Chair Kristina Haase) |
13:30 – 14:00 | Genetic engineering for cardiac fibrosis Jennifer Davis – University of Washington Seattle, US |
14:00 – 14:15 | Characterization of aging-associated immune alterations in post myocardial infarction mouse models Diyaa Ashour – Universitätsklinikum Würzburg, Germany |
14:15 – 14:30 | The PD-1/PD-L1 pathway maintains an immunosuppressive environment essential for neonatal heart regeneration Ning Liu – UT Southwestern Medical Center, USA |
14:30 – 15:00 | Adaptive immunity in heart disease Pilar Alcaide – Tufts University School of Medicine, Boston, USA |
15:00 – 15:30 | Coffee break and meet the speakers |
15:30 – 15:45 | Mitochondrial GRK2 dependent regulation of myocardial cellular and transcriptional composition after ischemic injury Samuel Slone – Duke University, USA |
15:45 – 16:00 | Border-zone cardiomyocytes and macrophages contribute to ECM remodeling to promote cardiomyocyte invasion during cardiac regeneration Arica Beisaw – Heidelberg University Hospital, German Center for Cardiovascular Research (DZHK) Heidelberg/Mannheim, Germany |
16:00 – 16:30 | Epigenetic therapies for diastolic dysfunction Timothy McKinsey – University of Colorado Anschutz Medical Campus, USA Not available on demand |
16:30 – 17:00 | Flash talks |
17:00 – 18:30 | Poster Session 1 (odd numbers) with beer and snacks |
18:30 – 20:00 | Dinner in Canteen |
20:00 – 22:00 | Pub Quiz |
Time (Europe/Berlin) | Session |
---|---|
09:00 – 11:30 | Session 4: Where cardiomyocyte biology meets vascular biology (Chair Pilar Alcaide) |
09:00 – 09:30 | Mechanisms and cellular heterogeneity in coronary vessel formation Holger Gerhardt – Max Delbrück Center, Germany |
09:30 – 09:45 | Uncoupling hypertension from cardiac remodeling Anna Kaganovsky – Technion, Israel |
09:45 – 10:00 | NNT is required for heart failure with preserved ejection fraction Mark Emile Pepin – Brigham and Women’s Hospital, Harvard Medical School, USA |
10:00 – 10:30 | Advancing tissue-specific vascularized in vitro models – a snapshot on human cardiac microvasculature Kristina Haase – EMBL Barcelona, Spain Not available on demand |
10:30 – 11:00 | Coffee break and meet the speakers |
11:00 – 11:15 | Endothelial inactivation of Sox9 protects from aging-induced cardiac fibrosis and heart failure Felix Trogisch – European Center for Angioscience & Heidelberg University, Germany Not available on demand |
11:15 – 11:30 | Egr1 is a master regulator of regenerative senescence and cardiac repair Lingling Zhang – Weizmann Institute of Science, Israel |
11:30 – 12:00 | Vascular control of short and long distance communication Hellmut Augustin – Heidelberg University & DKFZ Heidelberg, Germany Not available on demand |
12:00 – 13:30 | Vegetarian lunch |
12:40 – 13:30 | Closing the gap between academia and industry Moderator: Timothy McKinsey Panel members: Ann-Kristin Müller, Bert Klebl, Giulia Borghetti, Eric N. Olson, Eva van Rooij, Pablo Hofbauer |
13:30 – 16:30 | Session 5: Where cardiovascular biology meets mechanobiology (Chair Enzo Porrello) |
13:30 – 14:00 | Jagged1 as an endothelial cell mechanoreceptor Cecilia Sahlgren – Åbo Akademi University and Eindhoven University of Technology, Finland |
14:00 – 14:15 | Cardiac fibroblasts play an important role in the development of Marfan related cardiomyopathy Jeffrey Aalders – Ghent University, Belgium |
14:15 – 14:30 | The Melusin cardioprotective chaperone tunes lipid metabolism to promote cardiac resilience to stress Giulia Savorè – University of Torino, Italy |
14:30 – 15:00 | Endothelial mechanotransduction in vascular development and disease Stephan Huveneers- Amsterdam UMC, The Netherlands |
15:00 – 15:15 | Regulation of ventricular contractility driven atrial ballooning by the alpha actinin family member ACTN4 Dylan Burnette – Vanderbilt University, USA |
15:15 – 15:30 | Hydroxytyrosol: Shielding vascular grafts against intimal hyperplasia Nadiah Sulaiman – Universiti Kebangsaan Malaysia, Malaysia |
15:30 – 16:00 | Coffee break and meet the speakers |
16:00 – 16:30 | Perfusable on-chip vascular network for mechanobiology and developmental biology Ryuji Yokokowa – Kyoto University, Japan |
16:30 – 17:00 | Flash talks |
17:00 – 18:30 | Poster Session 2 (even numbers) with beer and snacks |
18:30 – 19:00 | Networking pre-dinner drinks |
19:00 – 21:00 | Conference dinner |
21:00 – 00:30 | Party – ATC Foyer |
Time (Europe/Berlin) | Session |
---|---|
09:00 – 13:00 | Session 6: Molecular circuits of heart disease (Chair Norbert Frey) |
09:00 – 09:30 | New concepts to treat arrhythmogenic cardiomyopathy Eva van Rooij – Hubrecht Institute, The Netherlands Not available on demand |
09:30 – 10:00 | Epitrancriptomic targets in heart disease Federica Accornero – Brown University, USA Not available on demand |
10:00 – 10:15 | Cardiac sympathetic neuropathology supports the multicellularity of Arrhythmogenic Cardiomyopathy Induja Perumal Vanaja – University of Padua, Italy Not available on demand |
10:15 – 10:30 | Elucidating the molecular mechanisms and cellular specificity of HDAC inhibitor efficacy in diastolic dysfunction Joshua Travers – University of Colorado Anschutz Medical Campus, USA |
10:30 – 10:45 | Re-evaluating the fetal gene program at single-cell resolution in dilated cardiomyopathy (DCM) Neda Rahmani Mehdiabadi – Murdoch Children’s Research Institute, Australia |
10:45 – 11:15 | Coffee break and meet the speakers |
11:15 – 11:45 | Regulation of splicing in cardiomyopathies Lars Steinmetz – EMBL Heidelberg, Germany |
11:45 – 12:45 | Keynote: Toward the genetic correction of heart and muscle disease Eric N. Olson – UT Southwestern Medical Center at Dallas, USA Not available on demand |
12:45 – 13:00 | Closing Remarks and Poster Prize Announcements |
13:00 – 13:15 | Packed Lunch and departure |
On-site registration fees include admission, conference materials, meals and coffee breaks. Participants are expected to book and pay their own accommodation and travel expenses.
Virtual registration fees include access to all of the talks (livestreamed and on demand) and facility to submit questions.
On-site Academia | €350 |
On-site PhD Student | €250 |
On-site Industry | €750 |
On-site Journal Editors* | €200 |
Virtual Academia | €150 |
Virtual PhD Student | €100 |
Virtual Industry | €250 |
* Editors from scientific journals are allowed to attend at a reduced rate, but asked to contribute to the conference in return by taking part in ‘meet the editors’ sessions or other planned activities within the programme.
A letter to support your visa application will be issued, on request, once payment of the registration fee is confirmed. We recommend that you book your visa appointment as soon as possible, to avoid any delay with your visa application.
Accredited journalists may be eligible to register for complimentary press registration. Registrants may be required to provide accreditation or equivalent proof of press membership after registration. Please contact Catherine Casas-Saavedra for more information. Please note that we do not offer complimentary registrations for editors of scientific journals.
Registration will be on a first come, first served basis. Your place can only be confirmed after payment of the registration fee. If you are added to our waiting list, please consider taking advantage of our offerings to participate virtually.
On-site participants: Types of payments accepted are international bank transfers and credit card payments.
Virtual participants: We are only able to accept card payments. In exceptional cases we can accept bank transfers. Please contact Catherine Casas-Saavedra for details.
Only participants registering to attend the on-site event are eligible to submit an abstract. Abstracts will not be accepted from virtual participants.
After registration you can submit your abstract via a separate link that will be provided in the email confirmation. Alternatively, you can access the link on the confirmation page directly after registering. The same login credentials are used for both processes.
Please note:
Abstract body: The limit of 2000 characters refers to manually typed text and excludes spaces. If an error occurs try using a different web browser (preferably Google Chrome or Mozilla Firefox).
If you copy-paste the text into the form, hidden formatting might still be included which may cause the text to exceed the 2,000 character limit resulting in an error message. We recommend you clear all formatting before pasting in the text.
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Kindly mark only one author in the role of First Author and please don’t forget to indicate who will be the Presenter.
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For detailed instructions on how to submit a conference abstract, follow the instructions provided in this video.
Please check our FAQs pages for further information on how to submit an abstract.
Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers, travel grants, and childcare grants.
Your place in the meeting is only confirmed by paying the registration fee, which is mandatory even when receiving a fee waiver.
The fee waiver will cover the registration sum that you have paid to attend the course or conference.
The travel grant will cover the cost of travel to an on-site event (airfare, train, bus, taxi, accommodation, visa, and/or registration fees*) and is provided up to specified caps which are normally as follows:
–up to €400 for participants travelling to an EMBL Conference or EMBO|EMBL Symposium from within Europe.
–up to €1000 for participants travelling to an EMBL Conference or EMBO|EMBL Symposium from outside Europe.
–up to €500 for any participant travelling to an EMBO Workshop.
–up to €1000 for any participant working in Chile, India, Singapore or Taiwan travelling to an EMBO Workshop.
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*Registration fees are only covered for EMBO Workshops
For DFG Grants, participants must travel in economy class, no business’ travel will be covered, and the hotel accommodation should not exceed 95 EUR per night.
The organisers may reduce the grant cap to accommodate more participants. Recipients will be notified of their travel cap amount when they are informed of the outcome of their application. Original receipts must be provided with your signature for all costs incurred within two months of completion of travel.
There is the possibility to apply for a childcare grant to offset child care costs incurred by participants, speakers, and organisers when attending a conference.
Eligible costs include (but are not limited to) fees for a baby-sitter or child-care facility, and travel costs for a caregiver. Please note that priority will be given to early stage researchers. In order to apply for this grant, you must be registered by the abstract submission deadline. There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants.
On-site participants
You may apply for financial assistance when submitting your abstract. In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career. Application for financial support will not affect the outcome of your registration application.
Virtual participants
If you are attending virtually, you can apply for financial assistance in the submission portal by the abstract deadline. Read the instructions on how to apply for financial assistance. Only submissions for financial assistance will be accepted. Presentation abstracts cannot be submitted here and will be declined.
In your application you will be asked to summarise your current work, answer questions regarding why your lab cannot fund your attendance, and how your attendance will make a difference to your career. Application for financial support will not affect the outcome of your registration application.
The scientific organisers will select the recipients of all financial assistance during the abstract selection process. Results will be announced approximately 6 – 8 weeks before the event start date, however for some events this may be delayed. Selection results do not impact your admission to the meeting. Selection is based on scientific merit, your current work or study location, the reasons for needing financial support, and the impact this event will have on your career.
Costs will be reimbursed after the meeting only once a reimbursement form and original receipts (from travel costs) have been received.
View our list of external funding opportunities and information on attending a conference as an event reporter.
For further information about financial assistance please refer to the FAQ page.
Accommodation is not included in the conference registration fee.
The hotels below have rooms on hold for participants until Tuesday, 23 January, in some cases at special rates. Please email the hotel directly, quoting the booking code NCB24-01 to confirm the exact price of the room.
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The bus stops for this conference are:
View Conference shuttle bus stops and hotels in a larger map. Please note that not every bus stop will be used for every event.
Address: EMBL, Meyerhofstraße 1, 69117 Heidelberg, Germany. For further information on getting to EMBL Heidelberg visit Public Transportation to the Venue. For information about accommodation and local transportation please refer to the FAQ page.
All meals and coffee breaks are included in the registration fee. Our catering staff will prepare a wide variety of vegetarian meals, meat and fish dishes, soups, pasta, fresh fruit and vegetables, as well as a variety of desserts.
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No food or drinks are allowed in the auditorium.
There are lockers available next to the stairs leading down into the Auditorium. You will find some of those equipped with sockets to charge your smartphone/tablet etc.
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If first aid is required …
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Beyond first aid…
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A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing.
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Hello | Hallo |
Goodbye | Auf Wiedersehen (formal) Tschüss (informal) |
Good morning | Guten Morgen |
Good afternoon | Guten Tag |
Good evening | Guten Abend |
Good night | Gute Nacht |
I’m sorry | Es tut mir leid |
Excuse me… | Entschuldigen Sie |
How are you? | Wie gehts? |
I’m fine thanks. And you? | Mir geht es gut , danke. Und Dir/Ihnen? |
What is your name | Wie heißen Sie? (formal) Wie heißt du? (informal) |
My name is.. | Ich heiße.. |
Do you speak English | Sprechen Sie englisch? |
I don’t understand | Ich verstehe nicht |
Please speak more slowly | Können Sie bitte langsamer sprechen |
Thank you | Dankeschön |
Where is the toilet? | Wo ist die Toilette? |
Please call me a taxi | Bitte rufen Sie mir ein Taxi |
How do I get to….? | Wie komme ich zum/zur…..? |
A beer/two beers please | Ein Bier/zwei Bier bitte |
A glass of red/white wine please | Ein Glas Rot/Weisswein bitte |
The menu, please | Die Speisekarte, bitte |
Is there a local speciality? | Gibt es eine Spezialität aus dieser Gegend? |
I’m vegetarian | Ich bin Vegetarier |
It was delicious | Es war hervorragend |
The bill, please | Die Rechnung, bitte |
I have a headache | Ich habe Kopfschmerzen |
I have a sore throat | Ich habe Halsschmerzen |
My stomach hurts | Ich habe Magenschmerzen |
I’m allergic to | Ich bin allergisch gegen |
I need a doctor who speaks English | Ich brauche einen Arzt, der englisch spricht. |
* Talks will only be recorded upon speaker’s consent
Please note that only on-site participants are able to submit abstracts and participate in the poster sessions.
We are using an event platform for this conference. More information about the platform will be shared ahead of the conference.
Additional information can be found in our Code of Conduct.
It is important to stay healthy and move around, especially when you are attending an event virtually. We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event.
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The programme is planned based on the Europe/Berlin time zone, unless otherwise stated. Please take your time zone into consideration when planning your attendance.
Please find additional information including FAQs, terms and conditions, COVID-19 safety policy and travelling to EMBL on our Information for participants page.
COVID-19 information for on-site events at EMBL Heidelberg can be found in our COVID-19 FAQs.
Gold sponsor
Silver sponsor
Event sponsor
Event supporter
Disease Models & Mechanisms (The Company of Biologists)
Media partners
EMBO Molecular Medicine, an EMBO Press journal
Development, The Company of Biologists journal
International Union of Biochemistry and Molecular Biology
Medinformatics, a Bon View Publishing journal
Open Biology, a Royal Society journal
Sponsorship opportunities
We offer a variety of event sponsoring possibilities, with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget. Discounts are available for companies sponsoring multiple events at EMBL Heidelberg. View other conferences, or contact sponsorship@embl.org for further information on sponsoring possibilities.
If you are interested in becoming a media partner of this event, please visit our media partnerships webpage.
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For on-site participants only.
This industry workshop will be hosted by our sponsor IVIM Technology prior to the EMBO Workshop: The new cardiobiology
on Tuesday, 20 February 2024, 11:45 – 12:45
Participation in this workshop is free of charge for registered on-site conference attendees. The number of available places is limited (first come, first served).
All registered conference attendees will receive an email with a registration link shortly.
ABSTRACT
Suction-assisted Imaging Window for Stabilized Intravital Imaging of Lung and Heart in a Live Animal
Pilhan Kim, Ph.D.
Professor Korea Advanced Institute of Science and Technology (KAIST),
Graduate School of Medical Science and Engineering, Republic of Korea
Download full abstract with images here.
Date: 20 - 23 Feb 2024
Location: EMBL Heidelberg and Virtual
Venue: EMBL Advanced Training Centre
Deadline(s):
Abstract submission: Closed
Registration (On-site): Closed
Registration (Virtual): Closed
Organisers:
Contact: Catherine Casas-Saavedra