Protein Synthesis and Translational Control

Overview

Conference Overview

Translational control is a major focus of attention that extends to many fields, including developmental biology, neurobiology, cell physiology, disease, synthetic and systems biology, among others. In addition to messenger RNA translation, the conference will feature advances in the fields of epitranscriptomics and non-coding RNAs that influence the translation process. Data-rich high-throughput technologies and structural advances will also be central, as they are pushing the field forward in manners that were unthinkable only few years ago, and are helping to create a “systems” view of translation.

With the increasing appreciation of the integration between different steps of gene expression, the conference will explore the connections between translation, mRNA turnover, nonsense-mediated decay, RNA localisation, splicing, etc. Finally, many alternatives to the classical “one message makes one protein” concept are being unraveled which increase the potential for regulation. These alternatives will be featured, as well as the role of translational regulation in diseases as diverse as cancer, neurological disorders or infectious diseases.

Session Topics

• Translation initiation
• Ribosome, elongation, termination
• Metabolism and disease
• RNP complexes
• Interconnections and turnover
• Methods and systems approaches

This conference is partnered with Cold Spring Harbor Laboratory (CSHL).

Speakers

Keynote Speakers

Susan L. Ackerman

University of California, San Diego

USA

Harry F. Noller

University of California, Santa Cruz

USA

Erin M. Schuman

Max Planck Institute for Brain Research

Germany

Speakers / Session Chairs

Alfredo Castello

University of Oxford

United Kingdom

Jeffrey A. Chao

Friedrich Miescher Institute for Biomedical Research

Switzerland

Rivka Dikstein

Weizmann Institute of Science

Israel

Anne-Claude Gingras

Lunenfeld-Tanenbaum Research Institute

Canada

Myriam Gorospe

National Institute on Aging

USA

Daniel N. Wilson

University of Hamburg

Germany

Scientific Organisers

Fátima Gebauer

Centre for Genomic Regulation (CRG)

Spain

Wendy Gilbert

Yale University

USA

Matthias W. Hentze

EMBL Heidelberg

Germany

Christian Spahn

Charité Berlin

Germany

Conference Organisers

Tim Nürnberger

EMBL Heidelberg

Germany

Programme