Liquid Biopsies

Overview

Course Overview

Liquid biopsies have the advantage of being largely non-invasive and providing a vast amount of information for the detection and monitoring of diseases such as cancer. This course will provide hands-on experience in the several techniques to detect and analyse circulating tumor cells (CTCs), cell free tumor DNA (ctDNA) and proteins. Participants will have the opportunity to learn all aspects ranging from proper sampling through error free sequencing to data analysis. Lectures will also cover extracellular vesicles and clinical aspects using liquid biopsies, especially in the field of cancer diagnostics.

Audience

This course targets young scientists entering the field of liquid biopsy analysis and wanting to learn about the benefits and limitations of different approaches.

Modules/Resources

• Hands-on experience on ultra-sensitive mutation detection using sequencing
• Applications of digital PCR to the liquid biopsy workflow
• Protein analysis in liquid biopsis
• Data analysis and interpretations

Learning Outcomes

Participants will learn about the complete workflow in liquid biopsies, from sample preparation to data analysis and gain an overview of the current methods. Best practices, pitfalls as well as dos and don’ts will be discussed. After the course, participants should be able to assess the best methods for their application as well as design their experiments.

For an impression of the course check the 2018 course programme.

Speakers

Jörg Bantin

BioRad

Germany

Bianka Baying

EMBL Heidelberg

Germany

Francisco Bizouarn

BioRad

USA

Dan Brudzewsky

SeraCare Life Sciences

USA

Lei Chen

Uppsala University

Sweden

Anders Edsjö

Skåne University Hospital

Sweden

Tony E. Godfrey

Boston University School of Medicine

USA

An Hendrix

Ghent University

Belgium

Gustav Johansson

Sahlgrenska Academy at University of Gothenburg

Sweden

Mikael Kubista

Institute of Biotechnology and TATAA Biocenter

Czech Republic

Ulf Landegren

Uppsala University

Sweden

Klaus Pantel

University Medical Center Hamburg-Eppendorf

Germany

Michael Pfaffl

Technical University of Munich

Germany

Beata Ramasz

EMBL Heidelberg

Germany

Matthias Riebel

Thermo Fisher Scientific

Germany

Alexander Rotmann

Thermo Fisher Scientific

Germany

Anders Ståhlberg

Sahlgrenska Academy at University of Gothenburg

Sweden

Valerie Taly

Paris Descartes University

France

Laura Villacorta

EMBL Heidelberg

Germany

Thorsten Voss

QIAGEN

Germany

Scientific Organisers

Vladimir Benes

EMBL Heidelberg

Germany

Anders Ståhlberg

Sahlgrenska Academy at University of Gothenburg

Sweden

Course/Conference Organisers

Christina Dollt

EMBL Heidelberg

Germany

Programme