Reuven Agami
Netherlands Cancer Institute
The Netherlands
Overview
Why attend?
The regulation of the transcriptome is key to cellular processes that underpin cell biology, development and tissue function. All classes of cellular RNA are subject to posttranscriptional modification, be it by direct chemical modification, editing or non-templated nucleotide additions. Furthermore, regulatory RNA binding proteins and enzymes that can specifically recognise posttranscriptional RNA modifications have been identified. It is now emerging that the modification status of the transcriptome is dynamic and responsive to environmental/developmental cues. Together, this has elicited the realisation of an ‘epitranscriptome’ where posttranscriptional RNA modification coupled with recruitment of effector RNA binding proteins dynamically regulates genomic output and RNA function. Importantly, mutations in core-regulators of the epitranscriptome are causative in many human diseases or congenital disorders.
Aims
This meeting aims to explore all aspects of this emerging topic, from methods development to molecular mechanism as well as the mammalian physiological function of RNA modification and RNA binding proteins.
For an impression of the meeting you can check the 2016 conference agenda.
Speakers
Markus Bohnsack
University Medical Center Göttingen
Germany
Janusz Bujnicki
International Institute of Molecular and Cell Biology
Poland
Pierre Close
University of Liegé
Belgium
Ann Ehrenhofer-Murray
Humboldt University of Berlin
Germany
Michaela Frye
University of Cambridge, Wellcome Trust Medical Research Council Stem Cell Institute,
UK
Jacob Hanna
Weizmann Institute of Science
Israel
Chuan He
The University of Chicago
USA
Ya-Ming Hou
Thomas Jefferson University
USA
Narry Kim
Seoul National University
Korea
Ayelet Lamm
TECHNION Israel Institute of Technology
Israel
Sebastian Leidel
MPI for Molecular Biomedicine
Germany
Alexandra Lusser
Medical University of Innsbruck
Austria
Frank Lyko
German Cancer Research Center
Germany
Eric Miska
Gurdon Institute
UK
Shalini Oberdoerffer
NIH National Cancer Institute
USA
Mary O’Connell
CEITEC
Czech Republic
Tao Pan
The University of Chicago
USA
Shu-Bing Qian
Cornell University
USA
Gideon Rechavi
Tel Aviv University
Israel
Yanhong Shi
City of Hope
USA
Petr Svoboda
Institute of Molecular Genetics of the ASCR, v. v. i.
Czech Republic
Štěpánka Vaňáčová
CEITEC
Czech Republic
Yungui Yang
Beijing Institute of Genomics
China
Chengqi Yi
Peking University
China
Scientific Organisers
Michaela Frye
University of Cambridge, Wellcome Trust Medical Research Council Stem Cell Institute
UK
Chuan He
The University of Chicago
USA
Donal O’Carroll
University of Edinburgh
UK
Conference Organisers
Gwen Sanderson
EMBL Heidelberg
Germany
Programme
Date: 25 - 27 Apr 2018
Location: EMBL Heidelberg