Liquid Biopsies

Overview

Course Overview

Liquid biopsies have the advantage of being largely non-invasive and providing a vast amount of information for the detection and monitoring of diseases such as cancer. This course will provide hands-on experience in the most common techniques to detect and analyse circulating tumor cells (CTCs), cell free tumor DNA (ctDNA) and/or extracellular vesicles (exosomes) while also bringing in clinical aspects. Participants will have the opportunity to learn all aspects ranging from proper sampling through error free sequencing to data analysis.

Audience

This course targets young scientists entering the field of liquid biopsies and wanting to learn about the benefits and limitations of the approach.

Modules/Resources

• Hands-on experience on ultra-sensitive mutation detection using sequencing
• Application of digital PCR to the liquid biopsy workflow
• Protein analysis in liquid biopsis
• Data analysis

Learning Outcomes

Participants will learn about the complete workflow in liquid biopsies, from sample preparation to data analysis and gain an overview of the current methods. Best practices, pitfalls as well as do’s and don’ts will be discussed. After the course, participants should be able to assess the best methods for their application as well as design their experiments.

Speakers

Speakers and Trainers

Jörg Bantin

BioRad

Germany

Bianka Baying

EMBL Heidelberg

Germany

Francisco Bizouarn

BioRad

USA

Lei Chen

Uppsala University

Sweden

Ander Edsjö

Skåne University Hospital

Sweden

Stefan Filges

Sahlgrenska Academy at University of Gothenburg

Sweden

Tony E. Godfrey

Boston University School of Medicine

USA

An Hendrix

Ghent University

Belgium

Simon A. Joosse

University Medical Center Hamburg-Eppendorf

Germany

Mikael Kubista

Institute of Biotechnology and TATAA Biocenter

Czech Republic

Ulf Landegren

Uppsala University

Sweden

Rui Neves

Hospital Centre of the Heinrich-Heine University Düsseldorf,

Germany

Malte Paulsen

EMBL Heidelberg

Germany

Dinko Pavlinic

EMBL Heidelberg

Germany

Michael Pfaffl

Technical University of Munich

Germany

Matthias Riebel

Thermo Fisher Scientific

Germany

Alexander Rotmann

Thermo Fisher Scientific

Germany

Anders Ståhlberg

Sahlgrenska Academy at University of Gothenburg

Sweden

Valerie Taly

Paris Descartes University

France

Thorsten Voss

QIAGEN

Germany

Scientific Organisers

Vladimir Benes

EMBL Heidelberg

Germany

Anders Ståhlberg

Sahlgrenska Academy at University of Gothenburg

Sweden

Course Organisers

Christina Dollt

EMBL Heidelberg

Germany

Programme