Principles of Chromosome Structure and Function

Overview

Symposium Overview

This interdisciplinary symposium will highlight exciting new insights into the molecular principles that govern the functional framework of genomes in space and time. The meeting program will cover all levels of organisational complexity, from DNA to chromosomes, and in model systems ranging from bacteria to humans. This symposium will bring together scientists from different disciplines working at the forefront of chromosome biology to discuss the most recent advances in the field. A particular highlight will be the integration of discoveries made in different disciplines, including cell and molecular biology, biophysics, modelling, structural biology and biochemistry. By combining efforts from biology, physics and chemistry, the programme will open new horizons for future research in this exciting area of the life sciences.

Session Topics

• Chromosome dynamics
• Nuclear architecture
• DNA transcription, replication and segregation
• Hi-C and polymer modelling
• Molecular mechanisms
• Structural and functional imaging approaches
• Genome integrity
• Chromatin

Speakers

Keynote Speakers

Job Dekker

University of Massachusetts Medical School

USA

Edith Heard

Institut Curie

France

Speakers

Geneviève Almouzni

Institut Curie

France

Andrew Belmont

University of Illinois

USA

Wendy Bickmore

University of Edinburgh

UK

Camilla BjörkegrenSjögren

Karolinska Institutet

Sweden

Cees Dekker

Delft University of Technology

The Netherlands

William C. Earnshaw

University of Edinburgh

UK

Jan Ellenberg

EMBL Heidelberg

Germany

Susan M. Gasser

Friedrich Miescher Institute for Biomedical Research

Switzerland

Daniel Gerlich

Institute of Molecular Biotechnology,

Austria

Nick Gilbert

University of Edinburgh

UK

Stephan Gruber

University of Lausanne

Switzerland

John Marko

Northwestern University

USA

Leonid A. Mirny

Massachusetts Institute of Technology,

USA

Geeta Narlikar

University of California, San Francisco,

USA

Mario Nicodemi

University of Naples Federico II,

Italy

Clodagh O’Shea

The Salk Institute for Biological Studies,

USA

Frank Uhlmann

The Francis Crick Institute,

UK

Bas van Steensel

The Netherlands Cancer Institute,

The Netherlands

Scientific Organisers

Christian Häring

EMBL Heidelberg

Germany

Tatsuya Hirano

RIKEN

Japan

Ana Pombo

Max Delbrück Center for Molecular Medicine

Germany

Aaron F. Straight

Stanford Medical School

USA

Conference Organisers

Lea Hohmann

EMBL Heidelberg

Germany