Svante Pääbo
Max Planck Institute for Evolutionary Anthropology
Germany
EMBO | EMBL Symposium
This conference will take place at EMBL Heidelberg, with the option to attend virtually.
Combining genome-wide data from ancient and modern populations opens new windows into the past and, importantly, their integration with archaeological evidence and historical records elucidates aspects of human history and cultural evolution of past societies. Population-scale sequencing projects investigating past and present human diversity have already provided us with extraordinary insights into patterns of human variation and mobility through time and space. Moreover, genome-wide data from archaic human remains, such as Neandertals and Denisovans, allows to investigate human evolution in action and to provide direct insights into genetic changes that define our own lineage.
The available dataset of genome-wide data from present-day and archaic humans has risen exponentially since the first EMBO ‘Reconstructing the human past’ meeting in 2019. This has drastically enhanced our ability to carry out further large-scale studies on both global and local scales across deeply sampled time transects, making it now possible to ask and answer questions that were simply impossible to address before, in addition to motivating the development of new analytical methods. Critically, with new frontiers in data generation and analyses, questions on ethical practices in paleogenomics need to be considered.
Furthermore, the reconstruction of ancient pathogen genomes and metagenomic analysis of the oral and gut microbiomes provides us with molecular fossils to study microbial evolution through time. The potential of ancient DNA data to reconstruct genomic variation of human-associated animals and plants to understand the process of domestication and their evolutionary trajectory is equally promising to such studies in humans.
This meeting will involve scientists from population genetics, bioinformatics, microbiology, anthropology, archaeology and history and will strengthen future interactions in this young research field that is already changing the way we think about our past and will shape how we study genetic variation in the future.
“It was a wonderful opportunity to exchange science and get to know fellow researchers.” – Choongwon Jeong, Seoul National University, Seoul
“I can’t imagine a more dense and intense conference in the field of genomics of archaic humans. I extremely enjoyed the conference, and would like to give many thanks to the organisers who made it happen!” – Danat Yermakovich, cGEM, Institute of Genomics, University of Tartu, Estonia
Chinese Academy of Sciences
China
The Francis Crick Institute /
Max Planck for Evolutionary Anthropology
UK
University of Washington
USA
Brown University
USA
Yale School of Medicine
USA
Cinvestav UGA-Langebio
Mexico
University of Kansas
USA
University of Copenhagen
Denmark
Harvard University
USA
University of Lausanne
Switzerland
University of Tartu
Estonia
Middle East Technical University
Türkiye
Hungarian Academy of Sciences
Hungary
Australian National University
Australia
Harvard University
USA
Max Planck Institute for Evolutionary Anthropology
Germany
University of Copenhagen
Denmark
University of Chicago
USA
EMBL Heidelberg
Germany
Are you on social media? Post using #EESHuman and don’t forget to tag @EMBLEvents.
Time (Europe/Berlin) | Speaker |
---|---|
12:00 – 13:30 | Registration and Light Refreshments |
13:30 – 13:45 | Opening Remarks |
13:45 – 14:45 | Keynote Lecture: Archaic genomics Svante Pääbo – Max Planck Institute for Evolutionary Anthropology, Germany |
14:45 – 16:15 | Session 1 – Our closest living and extinct relatives Chairs: Johannes Krause – Max Planck Institute for Evolutionary Anthropology, Germany Pontus Skoglund – The Francis Crick Institute, UK |
14:45 – 15:15 | News from the Palaeolithic: ancient genomes and neandertal-human interactions Mateja Hajdinjak – The Francis Crick Institute, UK / Max Planck for Evolutionary Anthropology, Germany |
15:15 – 15:30 | The Neandertal growth hormone receptor Hugo Zeberg – Karolinska Institute, Sweden |
15:30 – 15:45 | Simultaneous bidirectional crispr-editing in cortical brain organoids uncovers hierarchical interactions among nearly fixed mutations specific to the sapiens lineage Cedric Boeckx – Catalan Institute for Advanced Studies and Research, Spain |
15:45 – 16:00 | Uncovering the noncoding variants that shaped human evolution David Gokhman – Weizmann Institute of Science, Israel |
16:00 – 16:15 | A structured coalescent model reveals deep ancestral structure shared by all modern humans Trevor Cousins – University of Cambridge, UK |
16:15 – 16:45 | Coffee Break and Meet the Speakers |
16:45 – 18:45 | Session 2 – Detecting patterns of selection Chairs: Pontus Skoglund – The Francis Crick Institute, UK Johannes Krause – Max Planck Institute for Evolutionary Anthropology, Germany |
16:45 – 17:15 | The MUC19 gene in denisovans, neanderthals, and modern humans: An evolutionary history of introgression and natural selection Emilia Huerta-Sanchez – Brown University, USA |
17:15 – 17:45 | Reconstructing the chronology of selection in maize domestication Jazmin Ramos-Madrigal – University of Copenhagen, Denmark Not available on demand |
17:45 – 18:00 | Three ancient DNA time transects from the Americas provide evidence for pre-contact selection in Coastal Brazil, the Central Andes, and Mesoamerica Alison Barton – Harvard University, USA |
18:00 – 18:15 | Recent expansion and evolutionary selection of human-specific NOTCH2NLB allele enhancing cortical neurogenesis Ikuo Suzuki – The University of Tokyo, Japan |
18:15 – 18:45 | Hundreds of findings of natural selection realize the promise of ancient DNA to elucidate human adaptation David Reich – Harvard University, USA |
18:45 – 19:30 | Flash Talk Session 1 #45 Marcos Araujo Castro e Silva #55 Nicolas Brucato #57 Zehui Chen #59 Daniel R. Cuesta-Aguirre #65 Michal Feldman #73 Lei Huang #77 Xiaowen Jia #79 Dilek Koptekin #85 Zhi Li |
19:30 – 21:15 | Dinner in EMBL Canteen |
21:15 – 22:45 | After dinner drinks with live jazz music in ATC Foyer |
Time (Europe/Berlin) | Speaker |
---|---|
09:00 – 14:30 | Session 3 – Reconstructing the genetic history of human populations Chairs: Ida Moltke – University of Copenhagen, Denmark Pontus Skoglund – The Francis Crick Institute, UK |
09:00 – 09:30 | The genetic history of Southern East Asia Qiaomei Fu – Chinese Academy of Sciences, China Not available on demand |
09:30 – 10:00 | Kinship and gender roles in early Neolithic societies: an Anatolian perspective Mehmet Somel – Middle East Technical University, Turkey |
10:00 – 10:15 | Exploring genetic relationships of ceramic age Caribbean individuals from the Dominican Republic Judith Ballesteros Villascán – Max Planck Institute for Evolutionary Anthropology, Germany |
10:15 – 10:30 | Steppe ancestry in Western Eurasia and the spread of the germanic languages Hugh McColl – Health Faculty, Globe Institute, Denmark |
10:30 – 11:00 | Coffee Break and Meet the Speakers |
11:00 – 11:30 | Reconstructing the evolution of the mutation rate and spectrum Kelley Harris – University of Washington, USA |
11:30 – 11:45 | Long-term continuity and genetic insights of the Punan Batu: Understanding hunter-gatherer resilience in Borneo Pradiptajati Kusuma – Laboratory of Genome Diversity and Diseases, Indonesia |
11:45 – 12:00 | First genetic insights into ancient population history in the Highlands of Papua New Guinea Konstantina Cheshmedzhieva – University of Vienna, Austria |
12:00 – 13:30 | Lunch and Meet the Editors |
13:30 – 14:00 | The future of our microbial past Christina Warinner – Harvard University, USA |
14:00 – 14:15 | Farming practices reduced generation intervals in post-glacial Western Eurasia Moisès Coll Macià – Aarhus University, Denmark |
14:15 – 14:30 | Paleogenomic analyses of archaeological remains reveal sex roles and mobility of ancient families in central Mexico Daniela Orozco – National Laboratory of Genomics for Biodiversity (UGA-LANGEBIO), CINVESTAV, Mexico |
14:30 – 15:00 | Coffee Break and Meet the Speakers |
15:00 – 15:30 | Flash Talk Session 2 #48 Rodrigo Barquera #49 William Barrie #50 Owyn Beneker #93 Santiago Gerardo Medina-Muñoz #101 Sandra Penske #107 Adam Ben Rohrlach #109 Susanna Sawyer #119 Laura Vilà Valls #123 Matthew Williams #125 Wipada Woravatin |
15:30 – 17:00 | Poster Session 1 (odd numbers) |
17:00 | Free Evening |
Time (Europe/Berlin) | Speaker |
---|---|
09:00 – 10:00 | Session 3 – Reconstructing the genetic history of human populations Chairs: Maanasa Raghavan – University of Chicago, USA Johannes Krause – Max Planck Institute for Evolutionary Anthropology, Germany |
09:00 – 09:30 | Reconstructing human migrations from genomic data across Latin America and the Pacific Andrés Moreno-Estrada – Cinvestav UGA-Langebio, Mexico |
09:30 – 09:45 | Using 858,635 individuals’ haplotype-sharing between British and Danish populations to infer the North Sea migration history Xiaolei Zhang – EMBL-EBI, UK |
09:45 – 10:00 | The origin and composition of the “forgotten people”: genetic analysis of the sarmatian-period population of the carpathian basin Oszkar Schutz – University of Szeged, Hungary |
10:00 – 10:30 | Coffee Break and Meet the Speakers |
10:30 – 11:30 | Session 4 – Ethical considerations and research practices in paleogenomics Chair: Maanasa Raghavan – University of Chicago, USA |
10:30 – 11:00 | Engaged research with indigenous communities in North America: an example from the Central and Southern Plains Jennifer Raff – University of Kansas, USA |
11:00 – 11:30 | The genetic origins and impacts of historical Papuan migrations into Wallacea Ray Tobler – Australian National University, Australia |
11:30 – 11:45 | Discussion: “Ethics” |
11:45 – 15:00 | Session 5 – Integrating genetic and historical evidence Chairs: Ida Moltke – University of Copenhagen, Denmark Johannes Krause – Max Planck Institute for Evolutionary Anthropology, Germany |
11:45 – 12:15 | Genomic investigations of the Early Medieval Southern Urals: synthesis and future perspectives Anna Szécsényi-Nagy – Hungarian Academy of Sciences, Hungary |
12:15 – 12:30 | A 4,000-years-old genome from Nuwayrat, Egypt Adeline Morez – The Francis Crick Institute; Liverpool John Moores University, UK |
12:30 – 12:45 | Unraveling the genomic history of European Jews Shamam Waldman – Harvard University, USA |
12:45 – 14:15 | Lunch |
14:15 – 14:45 | A genomic history of Rapa Nui and some methodological insights into ancient DNA analysis Anna Sapfo-Malaspinas – University of Lausanne, Switzerland |
14:45 – 15:00 | Archaeogenetic insights into the biological and cultural connectedness of bronze age Crete Alissa Mittnik – Max Planck Institute for Evolutionary Anthropology, Germany |
15:00 – 17:00 | Session 6 – Evolution of human pathogens, microbiome, and health Chairs: Johannes Krause – Max Planck Institute for Evolutionary Anthropology, Germany Pontus Skoglund – The Francis Crick Institute, UK |
15:00 – 15:30 | Ancient genomes and other evidence in the study of the evolution of human pathogens and immune response Christiana Scheib – University of Tartu, Estonia (Virtual) Not available on demand |
15:30 – 15:45 | Repeated plague infections across six generations of neolithic farmers Frederik Seersholm – University of Copenhagen, Denmark |
15:45 – 16:15 | Coffee Break and Meet the Speakers |
16:15 – 16:30 | Deep-sequencing and de novo assembly of microbial sequences through non-invasive sampling of 500-year-old Inca mummies Michelle Hämmerle – University of Vienna, Austria |
16:30 – 16:45 | Analysis of a 5,500-year-old Treponema pallidum-like genome from Sabana de Bogotá, Colombia Davide Bozzi – University of Lausanne, Switzerland |
16:45 – 17:00 | Paleogenomic reconstruction of pathogens from the 19th-century epidemic in Tlatelolco, Mexico Miriam Bravo – International Laboratory for Human Genome Research, Mexico |
17:00 – 17:45 | Flash Talk Session 3 #56 Théo Cavinato #58 Jérémy Choin #60 Roslyn Curry #68 Lucia Franchini #70 Keith Daniel Harris #76 Iseult Jackson #90 Javier Maravall López #99 Cecilia Padilla Iglesias #104 Niraj Rai #106 Iker Rivas-González #120 Maria Teresa Vizzari |
17:45 – 19:15 | Poster Session 2 (even numbers) |
19:15 – 21:00 | Conference Dinner |
21:00 – 23:30 | Conference Party |
Time (Europe/Berlin) | Speaker |
---|---|
09:30 – 12:00 | Session 7 – New methods and avenues for ancient genomic data analysis Chairs: Pontus Skoglund – The Francis Crick Institute, UK Ida Moltke – University of Copenhagen, Denmark |
09:30 – 10:00 | Ancient human DNA from archaeological sediment Diyendo Massilani – Yale School of Medicine, USA |
10:00 – 10:15 | A flexible new admixture dating approach to jointly analyse modern and ancient individuals sampled at different times Nancy Bird – University College London, UK |
10:15 – 10:30 | An efficient way to infer demographic history from the distribution of distances between heterozygous sites in diploid species Tommaso Stentella – Max Planck Institute for Molecular Genetics, Germany |
10:30 – 11:00 | Coffee Break and Meet the Speakers |
11:00 – 11:15 | Reconstructing phenotypic differences between ancient individuals Gili Greenbaum – The Hebrew University of Jerusalem, Israel |
11:15 – 11:30 | Accurate and robust inference of the relationship between two individuals using aDNA Alexandra Strang – Natural History Museum and UCL, UK |
11:30 – 11:45 | Population genetic analysis of Holocene Europeans using sediment nuclear DNA from open-air living spaces Niall Cooke – Max Planck Institute for Evolutionary Anthropology, Germany |
11:45 – 12:00 | High-resolution ancestry reconstruction of early Medieval Europe Leo Speidel – University College London; Francis Crick Institute, UK |
12:00 – 12:15 | Closing Remarks and Poster Prize Announcements |
12:15 | Packed Lunch and Departure |
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Hello | Hallo |
Goodbye | Auf Wiedersehen (formal) Tschüss (informal) |
Good morning | Guten Morgen |
Good afternoon | Guten Tag |
Good evening | Guten Abend |
Good night | Gute Nacht |
I’m sorry | Es tut mir leid |
Excuse me… | Entschuldigen Sie |
How are you? | Wie gehts? |
I’m fine thanks. And you? | Mir geht es gut , danke. Und Dir/Ihnen? |
What is your name | Wie heißen Sie? (formal) Wie heißt Du? (informal) |
My name is | Ich heiße… |
Do you speak English | Sprechen Sie englisch? |
I don’t understand | Ich verstehe nicht |
Please speak more slowly | Können Sie bitte langsamer sprechen |
Thank you | Dankeschön |
Where is the toilet? | Wo ist die Toilette? |
Please call me a taxi | Bitte rufen Sie mir ein Taxi |
How do I get to….? | Wie komme ich zum/zur…..? |
A beer/two beers please | Ein Bier/zwei Bier bitte |
A glass of red/white wine please | Ein Glas Rot/Weisswein bitte |
The menu, please | Die Speisekarte, bitte |
Is there a local speciality? | Gibt es eine Spezialität aus dieser Gegend? |
I’m vegetarian | Ich bin Vegetarier |
It was delicious | Es war hervorragend |
The bill, please | Die Rechnung, bitte |
I have a headache | Ich habe Kopfschmerzen |
I have a sore throat | Ich habe Halsschmerzen |
My stomach hurts | Ich habe Magenschmerzen |
I’m allergic to | Ich bin allergisch gegen |
I need a doctor who speaks English | Ich brauche einen Arzt, der englisch spricht |
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Media partners
International Union of Biochemistry and Molecular Biology
Medinformatics, a Bon View Publishing journal
Molecular Systems Biology, an EMBO Press Journal
Open Biology, a Royal Society journal
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EMBO | EMBL Symposia promote scientific communication and collaboration in the European research area. They provide scientists with a platform to discuss and exchange ideas on forward-looking topics and new developments in the life sciences.
Topics emphasise upcoming developments and the interdisciplinary nature of related fields. Jointly funded and organised by EMBO and EMBL – and complementary to their respective courses, workshops, and conference programmes – the symposia promote scientific communication and collaboration.
All symposia are held in the EMBL Advanced Training Centre (ATC) in Heidelberg, Germany, or virtually.
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Date: 17 - 20 Sep 2024
Location: EMBL Heidelberg and Virtual
Venue: EMBL Advanced Training Centre
Deadline(s):
Abstract submission: Closed
Registration (On-site): Closed
Registration (Virtual): Closed
Organisers:
Contact: Luana Ribeiro