Cryo-EM in Industry and Academia

Overview

Conference Overview

Recent technical developments in cryo-electron microscopy (cryo-EM) and cryo-tomography now allow structures of challenging targets relevant for the pharmaceutical industry (membrane proteins, multi-subunit complexes, chromatin complexes etc.) to be determined at unprecedented resolution. This workshop is aimed at members of the pharmaceutical and allied industrial sectors that use (or are considering using) cryo-EM in drug discovery and agricultural research, academic researchers interested in the impact of state-of-the-art cryo-EM in drug discovery, and cryo-EM support staff that want to learn more about the specific needs of industry.

Structural biologists from leading pharmaceutical companies and academia have joined forces to co-organise a science-driven meeting to exchange trends, ideas, use-cases, opportunities and challenges related to the use of cryo-EM in industry and academia.

Session Topics

• Cryo-EM overview
• Cryo-EM in industry workflows
• Cryo-EM “success stories” in industry and academia
• Sample optimisation for Cryo-EM
• Model of operation
• Future developments in Cryo-EM

Speakers

Priyanka Abeyrathne

GlaxoSmithKline Vaccines

USA

John Briggs

MRC Laboratory of Molecular Biology

UK

José Maria Carazo

CNB-CSIC

Spain

Claudio Ciferri

Genentech

USA

Timothy Dafforn

University of Birmingham

UK

Radostin Danev

University of Tokyo

Japan

Katharina Dürr

University of Oxford

UK

Yves Fomekong Nanfack

EMD Serono

USA

Wim Hagen

EMBL Heidelberg

Germany

Werner Kühlbrandt

Max Planck Institute of Biophysics

Germany

Mike Lawrence

Walter and Eliza Hall Institute of Medical Research

Australia

Christian Löw

EMBL Hamburg

Germany

Julia Mahamid

EMBL Heidelberg

Germany

Taiana Maia de Oliveira

AstraZeneca

UK

Stephen Muench

University of Leeds

UK

Kasim Sader

Thermo Fisher Scientific

UK

Patrick M. Sexton

Monash University

Australia

Chris Tate

MRC Laboratory of Molecular Biology

UK

Paul Thaw

TTP Labtech Limited

UK

Christian Wiesmann

Novartis

Switzerland

Peijun Zhang

Diamond Light Source Ltd

UK

Scientific Organisers

Chun-wa Chung

GlaxoSmithKline

UK

Christian Engel

Sanofi

Germany

Christoph Müller

EMBL Heidelberg

Germany

Friedrich Rippmann

Merck

Germany

Conference Organisers

Geoff Barnett

EMBL Heidelberg

Germany

Antonio Costantino

EMBL Heidelberg

Germany

Anna Schmidt

EMBL Heidelberg

Germany

Programme