Carsten Sachse
Forschungszentrum Jülich GmbH
Germany
EMBL Industry Workshop
This conference will take place at EMBL Heidelberg, with the option to attend virtually.
For late registrations please contact Lea Hohmann.
Due to the announced railway strike in Germany, there will be additional buses on Sunday evening, 28 January and Monday morning, 29 January from Frankfurt Airport to Heidelberg.
More information will be shared with all participants shortly.
The second edition of this workshop aims to bring the academic and industrial cryo-EM communities together to evaluate how the use of cryo-EM has developed 10 years on from the “cryo-EM resolution revolution” and build upon the successful first edition held at EMBL in 2019.
Showcasing high-quality research in academia and industry relevant and exemplary for both cryo-EM communities, the meeting will provide updates on recent and ongoing methodological developments. A particular focus will be on the integration of cryo-ET and cryo-EM with complementary imaging techniques, e.g. imaging across scales as well as other ‘omics’ technologies such as proteomics, genomics, and metabolomics. The integration of cryo-EM in the drug-discovery workflow will also be examined.
This event is part of the iNEXT-Discovery activities, and is co-organised with the Netherlands Cancer Institute (NKI). iNext Discovery is structural biology project funded from the European Commission Horizon 2020 scheme. Its main aim is to provide enable access to structural biology research infrastructures for all European researchers.
The feedback from our first workshop has been very positive. 100% of our participants stated that they would attend a repeat of this event.
“This was my first experience of an EMBL advanced training centre conference, and I hope it won’t be my last. The quality of the scientific discussion, training and opportunities for networking were exceptional.”
– Mohammad Bahar, University of Oxford, UK
“This workshop gave me an excellent overview of current opinions in the field.”
– Hans Raaijmakers, Thermo Fisher Scientific
University of Geneva
Switzerland
Imperial College London
UK
Genentech
USA
University of Cambridge
UK
The Francis Crick Institute
UK
EMBL Grenoble
France
Netherlands Cancer Institute / iNEXT Discovery
The Netherlands
Nanoimaging Services
USA
BASF
Germany
Scripps Research
USA
NovAliX
France
eBIC (Electron Biology Imaging Centre)
UK
Are you on social media? Post using #EMBLCryoEM and don’t forget to tag @EMBLEvents
Time (Europe/ Berlin) | Speaker |
---|---|
12:00 – 13:45 | Registration and light refreshments |
12:30 – 13:30 | Industry workshop “Facilitating cryo-EM by further automation: Smart EPU and Tomo Live Software” by Thermo Fishher Scientific (registration required) |
13:45 – 14:00 | Opening remarks by Simone Mattei |
14:00 – 17:15 | Session 1: Cryo-EM in Industry Workflows Session chair: Chiara Rapisarda |
14:00 – 14:45 | Keynote Lecture: Towards next generation cryo-EM imaging and visualization of heterogeneous membrane remodeling systems Carsten Sachse – Forschungszentrum Jülich GmbH, Germany Not available on demand |
14:45 – 15:15 | Rigid Fabs enable high-resolution structure determination of small proteins by cryoEM Claudio Ciferri – Genentech, USA |
15:15 – 15:45 | From implementing cryo-EM to effectively supporting structure-based drug design: an 8-year journey at NovAliX Denis Zeyer – NovAliX, France |
15:45 – 16:15 | Coffee Break |
16:15 – 16:45 | Novel Insight Drive Innovation for Successful Agriculture Jeremy Sloan – BASF, Germany Not available on demand |
16:45 – 17:00 | The industrialisation of cryo-EM at Astex Pharmaceuticals: a facility geared towards structure-based drug design Joanna Brown – Astex Pharmaceuticals, UK |
17:00 – 17:15 | CryoEM, a powerful tool for structure-based high-throughput epitope mapping of Next Generation Biologics Madhumati Sevvana – Sanofi, USA |
17:15 – 17:45 | Coffee Break |
17:45 – 19:15 | Poster Session |
19:15 – 20:45 | Dinner in Canteen |
20:45 – 22:15 | After dinner drinks in ATC Rooftop Lounge |
Time (Europe/ Berlin) | Speaker |
---|---|
09:00-12:00 | Session 2: Cryo-EM Applications in Research Session chair: Christoph Müller |
09:00 – 09:30 | Controlling complement Doryen Bubeck – Imperial College London, UK |
09:30 – 10:00 | Visualising proteolytic complexes in action: the small molecule switch Francesca Ester Morreale – Research Institute of Molecular Pathology, Austria |
10:00 – 10:30 | Molecular Architecture of FADD:Caspase-8 Signalling Complexes – from assembly to co-ordinated control of Life/Death Decisions Marion MacFarlane – University of Cambridge, UK |
10:30 – 11:00 | Coffee Break |
11:00 – 11:15 | Cryo-EM imaging of replicative helicase loading with yeast and human proteins Julia Greiwe – The Francis Crick Institute, UK Not available on demand |
11:15 – 11:30 | Large-scale conformational changes in a spliceosomal RNA helicase induced by allosteric inhibitors Gopika S – Freie Universität Berlin, Germany |
11:30 – 11:45 | Structural journey of an insecticidal protein against western corn rootworm Guendalina Marini – CSSB, Germany Not available on demand |
11:45 – 12:00 | Cryo-EM to study CRISPR-Cas interference and adaptation for type I multiprotein effectors Inga Songailiene – Vilnius University, Lithuania Not available on demand |
12:00 – 13:30 | Meet the speakers and Lunch |
12:30 – 13:15 | Industry workshop “Recent Advances in Grid Technology” by Quantifoil (registration required) |
13:30 – 17:00 | Session 3: Cryo-EM for Integrative Structural Biology Session chair: Chun-wa Chung |
13:30 – 14:00 | Enabling discovery by in-cell structural biology Julia Mahamid – EMBL Heidelberg, Germany Not available on demand |
14:00 – 14:30 | Universal strategies in cryoEM to visualize (small) drug targets Andreas Boland -University of Geneva, Switzerland |
14:30 – 15:00 | Accelerating vaccine discovery by multidisciplinary structural and digital innovative approaches combination Ilaria Ferlenghi – GSK, Italy |
15:00 – 15:30 | Coffee Break |
15:30 – 16:00 | From structure to sequence: Antibody discovery using cryoEM Andrew Ward – Scripps Research, USA |
16:00 – 16:15 | Finding antibodies in cryo-EM densities with CrAI Chiara Rapisarda – Sanofi, France |
16:15 – 16:30 | Structural Analysis of COPI Pathway in Chlamydomonas reinhardtii Grigory Tagiltsev – Max Planck Institute of Biochemistry, Germany |
16:30 – 17:00 | Coffee Break |
17:00 – 19:30 | Session 4: Recent Developments in cryo-EM Session chair: Anastassis Perrakis |
17:00 – 17:30 | CryoDRGN: Advances in deep learning for reconstructing structure and dynamics in vitro and in situ Ellen Zhong – Princeton University, USA remote talk |
17:30 – 18:00 | Physics-based interactive modelling with ISOLDE Tristan Croll – Altos Labs, USA |
18:00 – 18:30 | EasyGrid: automated sample preparation and control for cryo-imaging experiments Gergely Papp – EMBL Grenoble, France Not available on demand |
18:30 – 18:45 | Short break |
18:45 – 19:00 | Towards a better understanding of sample preparation within single particle cryo-EM Stephen Muench – University of Leeds, UK |
19:00 – 19:15 | CCP-EM Pipeliner/Doppio: Software tools for efficient, accurate, and reproducible management and automation of cryoEM processing workflows Matthew Iadanza – UKRI, UK |
19:15 – 19:30 | Troubleshooting cryo-EM sample preparation through cryo-EM grid hardware: past, present and future Wouter Van Putte – Puxano, Belgium |
19:30 – 21:00 | Dinner in Canteen |
21:00 – 23:00 | After Dinner Drink + Live Jazz |
Time (Europe/ Berlin) | Speaker |
---|---|
09:00 – 12:15 | Session 5: Access to cryo-EM for Industry and Academia Session chair: Simone Mattei |
09:00 – 09:30 | Cryo-EM in industry: still challenging, but many opportunities Giovanna Scapin – Nanoimaging Services, USA |
09:30 – 10:00 | Visualizing macromolecular structures in situ by cryo-electron tomography Peijung Zhang – eBIC (Electron Biology Imaging Centre), UK Not available on demand |
10:00 – 10:30 | Opportunities for using the iNEXT-Discovery access program and a future outlook to services for structural biology Anastassis Perrakis – NKI/iNEXT Discovery, The Netherlands |
10:30 – 11:00 | Coffee Break |
11:00 – 11:30 | Structures of human tRNAs by single particle cryo-EM Sebastian Glatt – Jagiellonian University Krakow / Malopolska Centre of Biotechnology, Poland Not available on demand |
11:30 – 11:45 | Cryo EM User facility at the Ernst Ruska-Centre, Forschungszentrum Jülich (Germany) Thomas Heidler – Forschungszentrum Juelich, Germany |
11:45 – 12:45 | Round Table Discussion on ‘Future perspectives (and sustainability) for cryo-EM in industry Panel members: Anastassis Perrakis and more to be confirmed |
12:45 – 13:00 | Closing Remarks and poster prizes |
13:00 – 14:30 | Lunch followed by departure |
13:15 – 14:15 | Imaging Centre Tours Separate Registration required – please await further information before event |
14:30 | Airport shuttle to Frankfurt airport, terminal 1 (30 EUR), tickets may be purchased on-site |
On-site registration fees include admission, conference materials, meals and coffee breaks. Participants are expected to book and pay their own accommodation and travel expenses.
Virtual registration fees include access to all of the talks (livestreamed and on demand) and facility to submit questions.
On-site Academia | €750 |
On-site PhD Student | €550 |
On-site Industry | €1050 |
Virtual Academia | €225 |
Virtual PhD Student | €175 |
Virtual Industry | €275 |
A letter to support your visa application will be issued, on request, once payment of the registration fee is confirmed. We recommend that you book your visa appointment as soon as possible, to avoid any delay with your visa application.
Accredited journalists may be eligible to register for complimentary press registration. Registrants may be required to provide accreditation or equivalent proof of press membership after registration. Please contact Lea Hohmann for more information.
Registration will be on a first come, first served basis. Your place can only be confirmed after payment of the registration fee. If you are added to our waiting list, please consider taking advantage of our offerings to participate virtually.
On-site participants: Types of payments accepted are international bank transfers and credit card payments.
Virtual participants: We are only able to accept card payments. In exceptional cases we can accept bank transfers. Please contact events@embl.de for details.
Only participants registering to attend the on-site event are eligible to submit an abstract. Abstracts will not be accepted from virtual participants.
After registration you can submit your abstract via a separate link that will be provided in the email confirmation. Alternatively, you can access the link on the confirmation page directly after registering. The same login credentials are used for both processes.
Please note:
Abstract body: The limit of 2000 characters refers to manually typed text and excludes spaces. If an error occurs try using a different web browser (preferably Google Chrome or Mozilla Firefox).
If you copy-paste the text into the form, hidden formatting might still be included which may cause the text to exceed the 2,000 character limit resulting in an error message. We recommend you clear all formatting before pasting in the text.
If you have special symbols in your text, make sure you are using Unicode characters, otherwise these will not be recognised.
Title: The title should not exceed 20 words. Only the first word of the title should start with a capital letter and the rest should be lowercase.
Authors and affiliations: Please fill in the author’s details as requested in the online form. The compulsory fields are: First Name, Last Name, Organisation Name (Affiliation or Company), Country and Email.
Kindly mark only one author in the role of First Author and please don’t forget to indicate who will be the Presenter.
Please enter your co-authors correctly via the system by adding accounts together with their organisation/institute. Do not copy-paste them into the body of the abstract text, as they will not be indexed in the abstract book.
Presentation types: When submitting your abstract, you can apply for an oral or poster presentation. A selection process will take place with the results announced 2-3 weeks after the abstract submission deadline.
For detailed instructions on how to submit a conference abstract, follow the instructions provided in this video.
Please check our FAQs pages for further information on how to submit an abstract.
Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers, travel grants, and childcare grants.
Your place in the meeting is only confirmed by paying the registration fee, which is mandatory even when receiving a fee waiver.
The fee waiver will cover the registration sum that you have paid to attend the course or conference.
The travel grant will cover the cost of travel to an on-site event (airfare, train, bus, taxi, accommodation, visa, and/or registration fees*) and is provided up to specified caps which are normally as follows:
–up to €400 for participants travelling to an EMBL Conference or EMBO|EMBL Symposium from within Europe.
–up to €1000 for participants travelling to an EMBL Conference or EMBO|EMBL Symposium from outside Europe.
–up to €500 for any participant travelling to an EMBO Workshop.
–up to €1000 for any participant working in Chile, India, Singapore or Taiwan travelling to an EMBO Workshop.
–up to €700 for any participant working in Croatia, Czech Republic, Estonia, Greece, Hungary, Italy, Lithuania, Luxembourg, Poland, Slovenia, and Turkey travelling to an EMBO Workshop.
*Registration fees are only covered for EMBO Workshops
The organisers may reduce the grant cap to accommodate more participants. Recipients will be notified of their travel cap amount when they are informed of the outcome of their application. Original receipts must be provided with your signature for all costs incurred within two months of completion of travel. Scanned copies cannot be accepted.
There is the possibility to apply for a childcare grant to offset child care costs incurred by participants, speakers, and organisers when attending a conference.
Eligible costs include (but are not limited to) fees for a baby-sitter or child-care facility, and travel costs for a caregiver. Please note that priority will be given to early stage researchers. In order to apply for this grant, you must be registered by the abstract submission deadline. There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants.
On-site participants
You may apply for financial assistance when submitting your abstract. In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career. Application for financial support will not affect the outcome of your registration application.
Virtual participants
If you are attending virtually, you can apply for financial assistance in the submission portal by the abstract deadline. Read the instructions on how to apply for financial assistance. Only submissions for financial assistance will be accepted. Presentation abstracts cannot be submitted here and will be declined.
In your application you will be asked to summarise your current work, answer questions regarding why your lab cannot fund your attendance, and how your attendance will make a difference to your career. Application for financial support will not affect the outcome of your registration application.
The scientific organisers will select the recipients of all financial assistance during the abstract selection process. Results will be announced approximately 6 – 8 weeks before the event start date, however for some events this may be delayed. Selection results do not impact your admission to the meeting. Selection is based on scientific merit, your current work or study location, the reasons for needing financial support, and the impact this event will have on your career.
Costs will be reimbursed after the meeting only once a reimbursement form and original receipts (from travel costs) have been received.
View our list of external funding opportunities and information on attending a conference as an event reporter.
For further information about financial assistance please refer to the FAQ page.
Accommodation is not included in the conference registration fee.
The hotels below have rooms on hold for participants until 3 January 2024, in some cases at special rates. Please email the hotel directly, quoting the booking code CPP-24-01 to confirm the exact price of the room.
Hotel ibis Heidelberg | Premier Inn Heidelberg City | ISG Hotel |
Staycity Aparthotel Heidelberg | B&B Hotel | Leonardo Hotel Heidelberg City Centre |
Meininger Heidelberg |
For travel information, please see here.
If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn ‘Event Ticket’ (called the ‘Veranstaltungsticket’ in German). This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km. You need to provide proof of your event attendance when purchasing the ticket.
For more information in English see here or in German see here.
You can book your ticket here.
Please see the bus schedule HERE as of 24 January 2024.
Conference shuttle buses are free of charge for participants, and depart from designated bus stops near the hotels to EMBL and back, mornings and evenings.
The bus stops for this conference are:
Additional buses due to railway strike (free of charge):
View Conference shuttle bus stops and hotels in a larger map. Please note that not every bus stop will be used for every event.
Address: EMBL, Meyerhofstraße 1, 69117 Heidelberg, Germany.
For more information about accommodation and travel, please refer to the FAQ page.
All meals and coffee breaks are included in the registration fee. Our catering staff will prepare a wide variety of vegetarian meals, meat and fish dishes, soups, pasta, fresh fruit and vegetables, as well as a variety of desserts.
Please wear your badge at all times when serving yourself.
No food or drinks are allowed in the auditorium.
There are lockers available next to the stairs leading down into the Auditorium. You will find some of those equipped with sockets to charge your smartphone/tablet etc.
In most places the electricity is 220 volts AC (50 cycles). An adaptor and a plug that fits the German socket may be needed for your appliances/laptop (i.e. American, Japanese, etc.). A USB charging station for electronic devices is available at the registration desk.
If you are interested in purchasing EMBL merchandise (products presented in the glass display in the registration area), please email the EMBL shop to place an order or get in contact with your Course Organiser.
Kindly note the EMBL shop is only open upon request and all purchases must be made in cash (Euros only).
Please read EMBL’s COVID-19 safety policy for on-site events.
Do not smoke in any EMBL building.
Eating and drinking is prohibited in the Auditorium and all laboratories.
Do not enter any restricted areas or the laboratories unless instructed to do so.
If first aid is required …
In case of fire …
Beyond first aid…
Please remember to bring your own medication, if needed, to the conference. Note that the next pharmacy is a 4-minute drive from the EMBL, but for many medications you will be required to see a doctor to get a prescription.
Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg. In any case, the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary.
Wi-Fi is available on campus using the EMBL-Events network and the event specific password, which will be provided on site. The eduroam network (secure, worldwide roaming access service developed for the international research and education community) is also available.
‘’Lost and Found’’ items are kept at the registration desk until the end of the conference.
There are lockers available on-site to store your luggage, which require a 2 EURO coin to operate. There is another luggage room on level E0, which is free to use but remains unlocked during the conference.
There is a nursing room available in the ATC Rooftop Lounge on level A29.
During the conference, an EMBL Photographer may be taking photos. If you would not like to appear in these, please inform the photographer or a member of the Course and Conference Office.
We can help to print your boarding pass/train ticket. Please send it to events@embl.de and collect your print-outs at the registration desk.
There is a room for prayer, meditation and yoga located on level E0 behind the Auditorium. Please be respectful of others using the room.
A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing.
During the event we provide conference shuttle buses to and from EMBL. In addition, there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time. Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page.
Hello | Hallo |
Goodbye | Auf Wiedersehen (formal) Tschüss (informal) |
Good morning | Guten Morgen |
Good afternoon | Guten Tag |
Good evening | Guten Abend |
Good night | Gute Nacht |
I’m sorry | Es tut mir leid |
Excuse me… | Entschuldigen Sie |
How are you? | Wie gehts? |
I’m fine thanks. And you? | Mir geht es gut , danke. Und Dir/Ihnen? |
What is your name | Wie heißen Sie? (formal) Wie heißt du? (informal) |
My name is.. | Ich heiße.. |
Do you speak English | Sprechen Sie englisch? |
I don’t understand | Ich verstehe nicht |
Please speak more slowly | Können Sie bitte langsamer sprechen |
Thank you | Dankeschön |
Where is the toilet? | Wo ist die Toilette? |
Please call me a taxi | Bitte rufen Sie mir ein Taxi |
How do I get to….? | Wie komme ich zum/zur…..? |
A beer/two beers please | Ein Bier/zwei Bier bitte |
A glass of red/white wine please | Ein Glas Rot/Weisswein bitte |
The menu, please | Die Speisekarte, bitte |
Is there a local speciality? | Gibt es eine Spezialität aus dieser Gegend? |
I’m vegetarian | Ich bin Vegetarier |
It was delicious | Es war hervorragend |
The bill, please | Die Rechnung, bitte |
I have a headache | Ich habe Kopfschmerzen |
I have a sore throat | Ich habe Halsschmerzen |
My stomach hurts | Ich habe Magenschmerzen |
I’m allergic to | Ich bin allergisch gegen |
I need a doctor who speaks English | Ich brauche einen Arzt, der englisch spricht. |
Please note that only on-site participants are able to submit abstracts and participate in the poster sessions.
We are using an event platform for this conference. More information about the platform will be shared ahead of the conference.
Additional information can be found in our Code of Conduct.
It is important to stay healthy and move around, especially when you are attending an event virtually. We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event.
Please use the Q&A function in the event platform.
If you have any other questions, you can go to the Help Desk in the event platform. Click on ‘more’ on the top menu and click Help Desk.
The programme is planned based on the Europe/Berlin time zone, unless otherwise stated. Please take your time zone into consideration when planning your attendance.
Please find additional information including FAQs, terms and conditions, COVID-19 safety policy and travelling to EMBL on our Information for participants page.
COVID-19 information for on-site events at EMBL Heidelberg can be found in our COVID-19 FAQs.
Event partner
Gold sponsor
Silver sponsor
Bronze sponsor
Event sponsor
CryoSol-World
Event supporter
Media partners
EMBO Reports, an EMBO Press journal
International Union of Biochemistry and Molecular Biology
Imaging and Microscopy, a Wiley magazine
Medinformatics, a Bon View Publishing journal
Open Biology, a Royal Society journal
Sponsorship opportunities
We offer a variety of event sponsoring possibilities, with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget. Discounts are available for companies sponsoring multiple events at EMBL Heidelberg. View other conferences, or contact sponsorship@embl.de for further information on sponsoring possibilities.
If you are interested in becoming a media partner of this event, please visit our media partnerships webpage.
EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials. One current scam campaign of which we are aware is conducted using the name ‘Judy Eastman’ (judy@gopcontact.a2hosted.com) and entails approaches to sponsors offering sponsorship opportunities on EMBL’s behalf. Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences, symposia and courses is handled by EMBL directly and is sent from an official EMBL account. EMBL does not work with any external providers on sponsorship acquisition.
Please also note that:
Suspicious communications purportedly from, for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship@embl.de.
For on-site participants only.
The following industry workshops will be hosted by the sponsors of EMBL Industry Workshop: Cryo-EM in academia and industry during the event.
In order to read the abstract of each workshop, please click on the corresponding links above.
Participation in these workshop is free of charge for registered on-site conference attendees. The number of available places is limited (first come, first served). You may register for and attend to both workshops.
All registered conference attendees will receive an email with a registration link shortly.
Want to let others know you’re attending this event? Take a look at our shareable media and feel free to use them in your social media channels or presentations.
Date: 29 - 31 Jan 2024
Location: EMBL Heidelberg and Virtual
Venue: EMBL Advanced Training Centre
Deadline(s):
Abstract submission: Closed
Registration (On-site): Closed
Registration (Virtual): Closed
Organisers:
Contact: Lea Hohmann