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Cryo-Electron Microscopy and 3D Image Processing – Virtual – Course and Conference Office

EMBO Practical Course

Cryo-Electron Microscopy and 3D Image Processing – Virtual

Overview

EMBL is committed to sharing research advances and sustaining scientific interaction throughout the coronavirus pandemic. We are delighted to announce that the course is going virtual and invite you to join us online.

Course Overview

Cryo-electron microscopy (cryo-EM) combined with image processing is currently undergoing what has been referred to as a “resolution revolution”, making it one of the most powerful techniques to address 3D molecular structure determination. It also has unique capabilities to obtain structural information in situ within complex environments, and to deal with heterogeneous samples. The methods are complex and under constant development, so in depth, advanced training of users is essential to ensure future users can adapt new technologies to expand into new areas and solve new biological problems. This course provides the theoretical and practical training covering the full cryo-EM breadth of techniques in order develop novel structure determination approaches.

Audience

The course is aimed at PhD students and PostDocs who already have some experience in cryo-EM and image processing, and who wish to learn the theory of cryo-EM image processing and more advanced practice with the aim of developing these techniques.

Modules/Resources

  • Single particle reconstruction (cisTEM, Relion, SPHIRE)
  • Subtomogram averaging (Dynamo)

Learning Outcomes

After this course, students should have learned advanced topics of cryo-EM data collection and image processing and be able to apply and adapt these techniques for challenging research projects.

Speakers, Trainers and Organisers

Speakers

Bettina Böttcher

University of Würzburg,

Germany

John Briggs

MRC Laboratory of Molecular Biology,

UK

Radostin Danev

The University of Tokyo,

Japan

Nikolaus Grigorieff

University of Massachusetts Medical School,

USA

Wim Hagen

EMBL Heidelberg

Germany

Richard Henderson

MRC Laboratory of Molecular Biology,

UK

Arjen Jakobi

Kavli Institute for Nanoscience Delft,

The Netherlands

Slavica Jonic

UniCNRS and Sorbonne Université,

France

Jan Kosinski

EMBL Hamburg,

Germany

Julia Mahamid

EMBL Heidelberg

Germany

Lori Passmore

MRC Laboratory of Molecular Biology

UK

Ardan Patwardhan

EMBL-EBI Hinxton,

UK

Pawel A. Penczek

The University of Texas, USA

Jürgen Plitzko

Max Planck Institute for Biochemistry,

Germany

Ali Punjani

University of Toronto,

Canada

Carsten Sachse

Forschungszentrum Jülich,

Germany

Sara Sandin

Nanyang Technological University,

Singapore

Michael Schatz

Image Science, Germany

Sjors Scheres

MRC Laboratory of Molecular Biology,

United Kingdom

Henning Stahlberg

University of Basel,

Switzerland

Maya Topf

Institute of Structural and Molecular Biology,

UK

Giulia Zanetti

Institute of Structural and Molecular Biology,

UK

Trainers

Alister Burt

IBS Grenoble France

Daniel Castaño-Díez

University of Basel,

Switzerland

Christos Gatsogiannis

Max Planck Institute of Molecular Physiology,

Germany

Timothy Grant

University of Wisconsin,

USA

Nikolaus Grigorieff

University of Massachusetts Medical School,

USA

Dari Kimanius

MRC Laboratory of Molecular Biology

UK

Thorsten Wagner

Max Planck Institute of Molecular Physiology,

Germany

Scientific Organisers

John Briggs

MRC Laboratory of Molecular Biology,

UK

Julia Mahamid

EMBL Heidelberg,

Germany

Lori Passmore

MRC Laboratory of Molecular Biology,

UK

Carsten Sachse

Forschungszentrum Jülich,

Germany

Henning Stahlberg

University of Basel,

Switzerland

Course Organiser

Maria Bacadare

Maria Mercedes Bacadare Goitia

EMBL Heidelberg

Germany

Programme

Date: 23 - 28 Aug 2020

Location: Virtual


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