The complex life of RNA

Time (Europe/Berlin)	Speaker
12:00 – 14:00	Arrival and registration with light refreshments
12:30 – 13:30	Pre-conference workshop “The unbiased characterisation of novel human protein coding genes using Ribosome Profiling” by Immagina Biotechnology S.r.l. (registration required)
14:00 – 14:15	Opening remarks by scientific organisers
14:15 – 15:00	Keynote lecture: Should it stay or should it go: the RNA exosome at the crossroads of RNA processing and decay Elena Conti – Max Planck Institute of Biochemistry, Germany
15:00 – 18:30	Session 1 – Co-transcriptional events Chairs: Reini Luco – Institut Curie, France Michaela Müller-McNicoll – Goethe University Frankfurt, Germany
15:00 – 15:30	Real time tracking of transcription translation coupling Olivier Duss – EMBL Heidelberg, Germany Not available on demand
15:30 – 15:45	Histone H1 regulates non-coding RNA turnover on chromatin in a m6A-dependent manner María Gómez – CBMSO (CSIC/UAM), Spain
15:45 – 16:00	Understanding the basis of transcription within heterochromatin Maja Gehre – Institute of Molecular Biotechnology (IMBA), Austria Not available on demand
16:00 – 16:45	Coffee break and Meet the speakers with: Elena Conti and Olivier Duss
16:45 – 17:00	Pol II pausing as a milestone on the road to complex animals Alexandra Chivu – Cornell University, USA
17:00 – 17:15	Extending the Hox molecular repertoire: from transcription to mRNA splicing Julie Carnesecchi – Centre National de la Recherche Scientifique (CNRS), France
17:15 – 17:30	A direct interaction between CPF and Pol II links RNA 3ʹ-end processing to transcription Manuel Carminati – MRC Laboratory of Molecular Biology, UK
17:30 – 17:45	U1 snRNP induces a CDK12-dependent checkpoint to protect transcripts from incorrect poly(A) site usage Jens Bohne – Hannover Medical School, Germany Not available on demand
17:45 – 18:00	Structural basis of non-coding roX RNA remodelling during dosage compensation Janosch Hennig – EMBL Heidelberg, Germany Not available on demand
18:00 – 18:30	Flash talk session 1 (2 min, 1 slide) #49 – Maxime Wery #91 – Alla Fedorova #93 – Sebastian Filbeck #123 – Dagmar Klostermeier #127 – Pawel Krawczyk #137 – Szu Shuo Lee #145 – Braulio Martinez #151 – Matthias Bastian Miosga #159 – Tsimafei Navalayeu #163 – Reini Luco Not available on demand
18:30 – 19:30	Poster viewing
19:30 – 21:00	Dinner in EMBL Canteen
21:00 – 22:30	Social event: science pub quiz in EMBL Canteen
21:00 – 22:30	Social event: after dinner drinks in ATC Foyer

Time (Europe/Berlin)	Speaker
09:00 – 12:15	Session 2 – RNA processing and modification Chairs: Aldema Sas-Chen – Tel Aviv University, Israel Sara Zaccara – Columbia University, USA
09:00 – 09:30	Decoding the epitranscriptome at single molecule resolution Eva Maria Novoa Pardo – Centre for Genomic Regulation, Spain
09:30 – 09:45	The novel nuclease complex PUCH processes piRNA 5’ ends in C. elegans Nadezda Podvalnaya – IMB Mainz, Germany
09:45 – 10:15	RNA processing in the human immune system Kristen Lynch – University of Pennsylvania, USA
10:15 – 10:45	Coffee break and Meet the speakers with: Eva Maria Novoa Pardo, Kristen Lynch and Stacy Horner
10:45 – 11:15	RNA modifications at the virus-host interface Stacy Horner – Duke University, USA Not available on demand
11:15 – 11:30	Functional splicing network: systematic approach towards understanding splicing regulation Malgorzata Ewa Rogalska – Centre for Genomic Regulation, Spain
11:30 – 11:45	Molecular bases of m6A regulation by non-canonical readers Andres Ramos – University College London, UK Not available on demand
11:45 – 12:00	The S. cerevisiae m6A-reader Pho92 promotes timely meiotic recombination by controlling key methylated transcripts Bertrand Séraphin – Institute of Genetics and Molecular and Cellular Biology (IGBMC), France Not available on demand
12:00 – 12:15	Flash talk session 2 (2 min, 1 slide) #153 – Miha Modic #171 – Marco Payr #183 – Diana Ribeiro #189 – Julian König #211 – Komal Soni #217 – Xue Strobl #221 – Anan Tarabieh Not available on demand
12:15 – 13:45	Lunch with Meet the editors (12:45 – 13:30)
13:45 – 15:00	Session 2 – RNA processing and modification (continued) Chairs: Aldema Sas-Chen – Tel Aviv University, Israel Sara Zaccara – Columbia University, USA
13:45 – 14:15	Mechanism and biology of RNA decay Stefan Ameres – Institute of Molecular Biotechnology, Austria
14:15 – 14:45	The YTHDF m6A readers are the key mechanism to dynamically regulate m6A mRNA degradation Sara Zaccara – Columbia University, USA Not available on demand
14:45 – 15:00	HIV-1 infection affects NAD capping of host cell RNA Hana Cahova – Institute of Organic Chemistry and Biochemistry of the CAS, Czech Republic
15:00 – 15:45	Coffee break and Meet the speakers with: Stefan Ameres, Clemens Plaschka and Florence Besse
15:45 – 17:30	Session 3 – RNA transport and localisation Chairs: Ina Huppertz – Max Planck Institute for Biology of Ageing, Germany Suzan Ruijtenberg – Utrecht University, The Netherlands
15:45 – 16:15	How to recognise and package nuclear mRNA Clemens Plaschka – Research Institute of Molecular Pathology, Austria
16:15 – 16:30	Material properties of RNP granules are tuned for their in vivo function Mainak Bose – EMBL Heidelberg, Germany
16:30 – 16:45	Hyperphosphorylation of mRNA decapping enzyme DCAP-2 and scaffold protein interactions govern embryonic mRNP condensates Thomas Duchaine – McGill University, Canada
16:45 – 17:15	Transport and remodeling of RNP granules in the nervous system Florence Besse – Institut de Biologie Valrose, France Not available on demand
17:15 – 17:30	Flash talk session 3 (2 min, 1 slide) #139 – Tina Lence #227 – Elise van der Salm #231 – Ellen van Vroonhoven #48 – Valerie Hilgers #52 – Pierre-Emmanuel Gleizes #60 – Fabien Bonneau Not available on demand
17:30 – 19:00	Poster session 1 (odd) List of posters
19:00	Free evening

Time (Europe/Berlin)	Speaker
09:00 – 12:00	Session 4 – RNA surveillance and decay Chairs: Niels H. Gehring – University of Cologne, Germany Sebastian Falk – University of Vienna, Austria
09:00 – 09:30	Condensation of a nuclear mRNA export factor regulates mRNA transport during stress Karsten Weis – ETH Zürich, Switzerland Not available on demand
09:30 – 09:45	Dual agonistic and antagonistic roles of ZC3H18 provides for co-activation of distinct nuclear RNA exosome decay pathways Patrik Polák – Aarhus University, Denmark Not available on demand
09:45 – 10:00	Deadenylation rate does not affect fast RNA degradation in yeast Cosmin Saveanu – Institut Pasteur, France
10:00 – 10:45	Coffee break and Meet the speakers with: Karsten Weis kindly sponsored by Eclipse Bioinnovations
10:45 – 11:00	A novel conditional Smg6 mouse model uncovers the role of NMD in circadian timekeeping David Gatfield – University of Lausanne, Switzerland
11:00 – 11:15	Conserved Erh1 protein orchestrates Mmi1 YTH-guided multi-modal mRNA silencing Auriane Rakitch – Université Grenoble Alpes, France
11:15 – 11:45	Synonymous codon usage regulates translation initiation Olivia Rissland – University of Colorado Anschutz Medical Campus, USA
11:45 – 12:00	Flash talk session 4 (2 min, 1 slide) #82 – Vladimir Despic #96 – Erika Girardi #112 – Francesco Ielasi #120 – Wael Kamel #130 – Sabrina Kueckelmann #138 – Young-suk Lee #146 – Santiago Martinez Lumbreras Not available on demand
12:00 – 13:30	Lunch
13:30 – 16:30	Session 5 – Translation Chairs: David Gatfield – University of Lausanne, Switzerland Olivia Rissland – University of Colorado Anschutz Medical Campus, USA
13:30 – 14:00	Massively parallel identification of zipcodes in primary cortical neurons Marina Chekulaeva – Max Delbrück Center for Molecular Medicine, Germany (Virtual Speaker)
14:00 – 14:15	Dynamics of human tRNA repertoires as a function of cell identity Lexi Gao – Max Planck Institute for Biochemistry, Germany
14:15 – 14:30	Ribosomal quality control in repeat-associated non-AUG translation of GC rich repeats Yi-Ju Tseng – University of Michigan, USA
14:30 – 15:15	Coffee break and Meet the speakers with: Marina Chekulaeva and and Katrin Karbstein kindly sponsored by Eclipse Bioinnovations
15:15 – 15:45	Quality control during ribosome assembly and function Katrin Karbstein – Scripps Research, USA
15:45 – 16:00	Maximizing therapeutic protein yield through human 5′ UTR optimization Cole Lewis – Yale University, USA
16:00 – 16:15	Hypoxic Translation is controlled by 3’UTR and the non-canonical Cap-binding Factor eIF4EHP in D. melanogaster Clara Hody – Université Libre de Bruxelles, Belgium Not available on demand
16:15 – 16:30	Flash talk session 5 (2 min, 1 slide) #158 – Isabel S. Naarmann-de Vries #184 – Nina Ripin #194 – Aldema Sas-Chen #204 – Sahil Sharma #220 – Jan-Niklas Tants #234 – Joseph Waldron #246 – Roko Zaja Not available on demand
16:30 – 18:00	Poster session 2 (even)
18:00 – 20:00	Gala dinner in EMBL Canteen
20:00 – 22:00	Social event: after dinner drinks with live music in ATC Foyer
22:00 – 00:00	Social event: DJ in ATC Foyer

Time (Europe/Berlin)	Speaker
09:30 – 12:00	Session 6 – mRNA regulation Chairs: Ayala Shiber – Technion-Israel Institute of Technology, Israel Jeffrey Chao – Friedrich Miescher Institute for Biomedical Research, Switzerland
09:30 – 10:00	Imaging the life and death of mRNAs in living cells Jeffrey Chao – Friedrich Miescher Institute for Biomedical Research, Switzerland
10:00 – 10:15	Alternative splicing of the stress-sensitive regulator CIRBP tilts the cellular response to infection by a bacterial pathogen Morgane Corre – École normale supérieure – PSL, France
10:15 – 10:45	Deciphering the dynamics of divergent co-translational assembly pathways Ayala Shiber – Technion – Israel Institute of Technology, Israel Not available on demand
10:45 – 11:15	Coffee break and Meet the speakers with: Jeffrey A. Chao, Edouard Bertrand and Bernd Bukau
11:15 – 11:45	Single molecule imaging reveals a new mechanism for RNA transport and local translation Edouard Bertrand – Institute of Human Genetics, France
11:45 – 12:00	Mechanism of ribosome-associated mRNA degradation in the tubulin autoregulation pathway Markus Höpfler – MRC Laboratory of Molecular Biology, UK
12:00 – 12:45	Keynote lecture: Co-translational folding and assembly of newly synthesized proteins revealed by ribosome profiling Bernd Bukau – Center for Molecular Biology of Heidelberg University (ZMBH) and German Cancer Research Center (DKFZ), Germany
12:45 – 13:00	Closing remarks
13:00	Packed lunch and departure
14:00	Optional: Shuttle bus to Frankfurt Airport (Terminal 1) Tickets can be purchased during the conference for 25 EUR with credit card only

On-site registration fees include admission, conference materials, COVID-19 safety measures, meals and coffee breaks. Participants are expected to book and pay their own accommodation and travel expenses.

Virtual registration fees include access to all of the talks (livestreamed and on demand) and facility to submit questions.

On-site Academia	€700
On-site PhD Student	€600
On-site Industry	€900
Virtual Academia	€175
Virtual PhD Student	€125
Virtual Industry	€225

NO visa support letters will be issued until payment of the registration fee is confirmed.

Accredited journalists may be eligible to register for complimentary press registration. Registrants may be required to provide accreditation or equivalent proof of press membership after registration. Please contact Diah Yulianti for more information. Please note that we do not offer complimentary registrations for editors of scientific journals.

Confirmation and payment

Registration will be on a first come, first served basis. Your place can only be confirmed after payment of the registration fee. If you are added to our waiting list, please consider taking advantage of our offerings to participate virtually.

On-site participants: Types of payments accepted are international bank transfers and credit card payments.

Virtual participants: We are only able to accept card payments. In exceptional cases we can accept bank transfers. Please contact events@embl.de for details.

Abstract submission

Only participants registering to attend the on-site event are eligible to submit an abstract. Abstracts will not be accepted from virtual participants.

After registration you can submit your abstract via a separate link that will be provided in the email confirmation. Alternatively, you can access the link on the confirmation page directly after registering. The same login credentials are used for both processes.

Please note:

Abstract body: The limit of 2000 characters refers to manually typed text and excludes spaces. If an error occurs try using a different web browser (preferably Google Chrome or Mozilla Firefox).

If you copy-paste the text into the form, hidden formatting might still be included which may cause the text to exceed the 2,000 character limit resulting in an error message. We recommend you clear all formatting before pasting in the text.

If you have special symbols in your text, make sure you are using Unicode characters, otherwise these will not be recognised.

Title: The title should not exceed 20 words. Only the first word of the title should start with a capital letter and the rest should be lowercase.

Authors and affiliations: Please fill in the author’s details as requested in the online form. The compulsory fields are: First Name, Last Name, Organisation Name (Affiliation or Company), Country and Email.

Kindly mark only one author in the role of First Author and please don’t forget to indicate who will be the Presenter.

Please enter your co-authors correctly via the system by adding accounts together with their organisation/institute. Do not copy-paste them into the body of the abstract text, as they will not be indexed in the abstract book.

Presentation types: When submitting your abstract, you can apply for an oral or poster presentation. A selection process will take place with the results announced 2-3 weeks after the abstract submission deadline.

For detailed instructions on how to submit a conference abstract, follow the instructions provided in this video.

Please check our FAQs pages for further information on how to submit an abstract.

Financial assistance

Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants. Availability is limited to participants attending on-site events in Heidelberg and will be indicated during the abstract or motivation letter submission process.

Your place in the meeting is only confirmed by paying the registration fee, which is mandatory even when receiving a fee waiver.

Registration fee waiver

The fee waiver will cover the registration sum that you have paid to attend the course or conference.

Travel grant

The travel grant will cover the cost of travel (airfare, train, bus, taxi, accommodation, visa, and/or registration fees*) and is provided up to specified caps which are normally as follows:

– up to €400 for participants travelling to an EMBL Course, EMBL Conference or EMBO|EMBL Symposium from within Europe.
– up to €1000 for participants travelling to an EMBL Course, EMBL Conference or EMBO|EMBL Symposium from outside Europe.
– up to €500 for any participant travelling to an EMBO Practical Course or EMBO Workshop.
– up to €1000 for any participant working in Chile, India, Singapore or Taiwan travelling to an EMBO Practical Course or EMBO Workshop.

*Registration fees are only covered for EMBO Practical Courses or EMBO Workshops

The organisers may reduce the grant cap to accommodate more participants. Recipients will be notified of their travel cap amount when they are informed of the outcome of their application. Original receipts must be provided with your signature for all costs incurred within two months of completion of travel. Scanned copies cannot be accepted.

Application

You may apply for financial assistance when submitting your motivation letter for courses, and abstract for conferences. In your application, you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career. Application for financial support will not affect the outcome of your registration application.

Selection

The scientific organisers will select the recipients of all financial assistance during the motivation letter or abstract selection process. Results will be announced approximately 6-8 weeks before the event start date, however for some events this may be delayed. Selection results do not impact your admission to the meeting. Selection is based on your current work or study location, the reasons for needing financial support and the impact this event will have on your career.

Reimbursement

Costs will be reimbursed after the meeting only once a reimbursement form and original receipts (from travel costs) have been received.

Further details

See our list of external funding opportunities and information on attending a conference as an event reporter.

For further information about financial assistance please refer to the FAQ page.

Accommodation is not included in the conference registration fee.

As further changes in our events are possible due to COVID-19, you should book flights, trains and hotels with flexible options and favourable cancellation conditions.

The hotels below have rooms on hold for participants until Sunday, 11 September, in some cases at special rates. Please quote the booking code EES22-10 and confirm the exact price of the room with the hotel directly.

Hotel Anlage	Hotel ibis Heidelberg	Staycity Aparthotel Heidelberg
Hotel Bayrischer Hof	ISG Hotel	Hotel Vier Jahreszeiten Heidelberg
B&B Hotel	Leonardo Hotel Heidelberg City Centre	Hotel Holländer Hof
Exzellenz Hotel & Boarding House	Hotel Monpti	Premier Inn Heidelberg City

Conference shuttle buses

Conference shuttle buses are free of charge for participants, and depart from designated bus stops near the hotels to EMBL and back, mornings and evenings.

The bus stops for this conference are:

• Staycity Aparthotel (Speyerer Str. 7)
• Kurfürsten-Anlage (Opposite Main Train Station)
• Premier Inn (Kurfürsten-Anlage 23)
• Leonardo Hotel Heidelberg City Center (Bergheimer Str. 63)
• Neckarmünzplatz (Heidelberg Tourist Information)
• Peterskirche (Bus stop)
• ISG Hotel (Im Eichwald 19)

View Conference shuttle bus stops and hotels in a larger map. Please note that not every bus stop will be used for every event.

Download the conference bus schedule here.

Further details

Address: EMBL, Meyerhofstraße 1, 69117 Heidelberg, Germany. For further information on getting to EMBL Heidelberg visit Public Transportation to the Venue. For information about accommodation and local transportation please refer to the FAQ page.

Catering

All meals and coffee breaks are included in the registration fee. Our catering staff will prepare a wide variety of vegetarian meals, meat and fish dishes, soups, pasta, fresh fruit and vegetables, as well as a variety of desserts.

Please wear your badge at all times when serving yourself.

No food or drinks are allowed in the auditorium.

Charging lockers

There are lockers available next to the stairs leading down into the Auditorium. You will find some of those equipped with sockets to charge your smartphone/tablet etc.

Electricity and charging station

In most places the electricity is 220 volts AC (50 cycles). An adaptor and a plug that fits the German socket may be needed for your appliances/laptop (i.e. American, Japanese, etc.). A USB charging station for electronic devices is available at the registration desk.

EMBL merchandise

If you are interested in purchasing an EMBL souvenir (products presented in the glass display in the registration area), please ask at the registration desk for more information.

Health and safety notes

Please read EMBL’s COVID-19 safety policy for on-site events.
Do not smoke in any EMBL building.
Eating and drinking is prohibited in the Auditorium and all laboratories.
Do not enter any restricted areas or the laboratories unless instructed to do so.

If first aid is required …

• The first aid room is located next to the ATC Registration Desk (room 10- 205).
• Dial the Emergency number 222 from any EMBL internal phone only.
• Where is the accident? What happened? How many injured?
• Emergency number 06221-387 7821 from mobile phones.
• Please report all accidents to the conference officer at the registration desk.

In case of fire …

• Press the nearest fire alarm button or the Emergency number 222 from any internal phone.
• A loud fire alarm will go off if an evacuation is required. On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points
• Do not use the lifts.

Beyond first aid…

Please remember to bring your own medication, if needed, to the conference. Note that the next pharmacy is a 4-minute drive from the EMBL, but for many medications you will be required to see a doctor to get a prescription.

Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg. In any case, the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary.

Internet

Wi-Fi is available everywhere on the premises (no password required), just log on to ATC-Guest. The eduroam network (secure, world-wide roaming access service developed for the international research and education community) is also available.

Lost and found

‘’Lost and Found’’ are kept at the registration desk until the end of the conference.

Luggage

There are lockers available on-site to store your luggage, which require a 2 EURO coin to operate. There is another luggage room on level E0, which is free to use but remains unlocked during the conference.

Nursing room

There is a nursing room available in the ATC Rooftop Lounge on level A29.

Photography

During the conference an EMBL Photographer may be taking photographs. If you would not like to appear in these, please inform the photographer or a member of the Course and Conference Office.

Printing

We can help printing your boarding passes/train ticket. Please send it to events@embl.de and collect your print-outs at the registration desk.

Room for prayer, yoga and meditation

There is a room for prayer, mediation and yoga located on level E0 behind the Auditorium. Please be respectful of other participants using the room.

Sightseeing

A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing

Travel to and from the venue

During the event we provide conference shuttle busses to and from EMBL. In addition, there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time. Information on the conference shuttle busses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page.

Useful German expressions

Where is the nearest Covid test centre?	Wo ist das nächste Covid-Testzentrum?
Hello	Hallo
Goodbye	Auf Wiedersehen
Good morning	Guten Morgen
Good afternoon	Guten Tag
Good evening	Guten Abend
Good night	Gute Nacht
I’m sorry	Tut mir leid
Excuse me…	Entschuldigen Sie
How are you?	Wie gehts?
I’m fine thanks. And you?	Mir geht es gut , danke, und dir/Ihnen?
What is your name	Wie heisst du? Wie heissen Sie?
My name is	Ich heisse
Do you speak English	Sprechen Sie Englisch?
I don’t understand	Ich verstehe nicht
Please speak more slowly	Können Sie bitte langsamer sprechen
Thank you	Dankeschön
Where is the toilet?	Wo ist die Toilette?
Please call me a taxi	Bitte rufen Sie mir ein Taxi
How do I get to….?	Wie komme ich zum/zur…..?
A beer/two beers please	Ein Bier/zwei Bier bitte
A glass of red/white wine please	Ein Glas Rot/Weisswein bitte
The menu, please	Die Speisekarte, bitte
Is there a local speciality?	Gibt es eine Spezialität aus dieser Gegend?
I’m Vegetarian	Ich bin Vegetarier
It was delicious	Es war hervorragend
The bill, please	Die Rechnung, bitte
I have a headache	Ich habe Kopfschmerzen
I have a sore throat	Ich habe Halsschmerzen
My stomach hurts	Ich habe Magenschmerzen
I’m allergic to	Ich bin allergisch gegen
I need a doctor who speaks English	Gibt es einen Arzt, der Englisch spricht?

What’s included?

• Access to all the livestreamed talks
• Video library of the recorded talks during and after the event
• Facility to submit questions

Please note that only on-site participants are able to submit abstracts and participate in the poster sessions.

Event platform

We are using an event platform for this conference. More information about the platform will be shared ahead of the conference.

Guidelines

• Do not broadcast the conference to unregistered participants.
• You are encouraged to tweet and post about the event. Tweet unless the speaker specifically says otherwise, but be mindful of unpublished data. 
• Please do not capture, transmit or redistribute data presented at the meeting.

Additional information can be found in our Code of Conduct.

Health and well-being

It is important to stay healthy and move around, especially when you are attending an event virtually. We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event.

How to ask questions

Please use the Q&A function in the event platform.

If you have any other questions, you can go to the Help Desk in the event platform. Click on ‘more’ on the top menu and click Help Desk. 

Time zone

The programme is planned based on the Europe/Berlin time zone, unless otherwise stated. Please take your time zone into consideration when planning your attendance.

Please find additional information including FAQs, terms and conditions, COVID-19 safety policy and travelling to EMBL on our Information for Participants page.

COVID-19 information for on-site events at EMBL Heidelberg can be found in our COVID-19 FAQs.