Patricia Bassereau
Institut Curie
France
EMBO | EMBL Symposium
This conference will take place at EMBL Heidelberg, with the option to attend virtually.
After a very engaging virtual first edition in 2021, this hybrid symposium on cell surface mechanics will bring together researchers across kingdoms of life interested in dynamic processes occurring at the cell surface. The focus will be on new technologies that empower studies of cell wall, cytoskeleton, and membrane biology, such as advanced imaging in in vitro and in vivo systems, as well as approaches combining molecular biology with computational and biophysical approaches.
The first edition started building a much-needed bridge between the wall and wall-less fields. This edition will cement that bridge, but turn the focus to the balance between keeping a particular cell morphology necessary for function, while allowing the dynamic processes that must occur at the cell surface. The goal is to inspire and induce collaborations across these communities to reach a comprehensive understanding of the biology at the cell surface, integrating cell wall, actin and membrane biochemistry, and biophysics with cell mechanics.
“Life at the Periphery was a rewarding opportunity to connect with people across the world and see some amazing science. I really appreciated in the different sessions how the organizers worked hard to pair seemingly different topics/fields of research together; it made us see the common threads of interest we have in different domains of biology.” – Michael Henderson, Institut Curie
Please see EMBL’s COVID-19 safety recommendations if attending the on-site event.
Institut Curie
France
MRC Laboratory of Molecular Biology
UK
Max Planck Institute of Molecular Physiology
Germany
University of Geneva
Switzerland
EMBL Heidelberg
Germany
EMBL Heidelberg
Germany
University of Massachusetts, Amherst
USA
McGill University
Canada
Stanford University
USA
National Central University
Taiwan
National Centre for Biological Sciences
India
AMOLF
Netherlands
University of California, San Francisco
USA
EPFL
Switzerland
Stanford University
USA
Virtual
Institute for Bioengineering of Catalonia (IBEC)
Spain
New York University
USA
MRC Laboratory of Molecular Biology
UK
Novo Nordisk Foundation Center for Stem Cell Medicine, reNEW
Denmark
The University of British Columbia
Canada
ETH Zürich
Switzerland
EMBL Heidelberg
Germany
Princeton University
USA
Stanford University
USA
EMBL Heidelberg
Germany
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Time (Europe/Berlin) | Speaker |
---|---|
12:30 – 14:00 | Registration and light refreshments |
14:00 – 14:15 | Opening remarks |
14:15 – 18:30 | Session 1 Chair: Alexandre Persat – EPFL, Switzerland |
14:15 – 14:45 | Cell adhesion and spreading on fluid membranes through microtubules-dependent mechanotransduction Patricia Bassereau – Institut Curie, France |
14:45 – 15:15 | Physical and embodied intelligence at the ciliated surface Kirsty Wan – University of Exeter, UK |
15:15 – 15:30 | Plasma membrane shape homeostasis in response to cell stretch Anabel-Lise Le Roux – Institute for Bioengineering of Catalonia, Spain |
15:30 – 16:00 | Chytrid fungi differentiate from cell types with an animal-like actin cortex to cells with actin patches and a fungal cell wall Lillian Fritz-Laylin – University of Massachusetts Amherst, USA |
16:00 – 16:45 | Coffee Break and Meet the speakers |
16:45 – 17:15 | Getting stressed versus going with the flow: the mechanical and diffusive properties of the bacterial cell envelope KC Huang – Stanford University, USA |
17:15 – 17:30 | Hydrogel-based Molecular Tension Fluorescence Microscopy for Investigating Integrin-mediated Rigidity Sensing Zheng Liu – Wuhan University, China |
17:30 – 17:45 | Waves on the surface of rewired oocytes: membrane patterning and cytoskeletal biomechanics Andrew Goryachev – University of Edinburgh, United Kingdom |
17:45 – 18:00 | Aberrant cortex contractions impact mammalian oocyte quality Elvira Nikalayevich – Center for Interdisciplinary Research in Biology; Collège de France, France |
18:00 – 18:30 | From the cell surface to the nucleus through integrins and intermediate filaments Pere Roca-Cusachs Soulere – Institute for Bioengineering of Catalonia and University of Barcelona, Spain |
18:30 – 20:00 | Dinner in Canteen |
20:00 – 21:30 | Drinks in ATC Roof top lounge |
Time (Europe/Berlin) | Speaker |
---|---|
09:00 – 12:00 | Session 2 Chair: Lillian Fritz-Laylin – University of Massachusetts Amherst, USA |
09:00 – 09:30 | Probing bacterial cell wall growth by tracing wall anchored protein complexes Chien-Jung Lo – National Central University, Taiwan |
09:30 – 09:45 | Mechanical polarity of the cell cortex Anumita Jawahar – PMMH, ESPCI / Institut Curie, France |
09:45 – 10:00 | Membrane to cortex attachment determines different mechanical phenotypes in LGR5+ and LGR5- colorectal cancer cells Sefora Conti – Institute for Bioengineering of Catalonia, Spain |
10:00 – 10:30 | Coffee Break and Meet the speakers |
10:30 – 11:00 | Multi-scale control of structural functionality in plants Anja Geitmann – McGill University, Canada |
11:00 – 11:15 | Contribution of cell mechanics in promoting supracellular migration Selena Gupta – New York University, United States of America |
11:15 – 11:30 | Hepatocyte apical bulkheads provide a mechanical means to oppose bile pressure Matthew Bovyn – Max Planck Institute for Cellular Biology and Genetics, Germany |
11:30 – 12:00 | A molecular view on the control of actin turnover by phosphate release Peter Bieling – Max Planck Institute of Molecular Physiology, Germany |
12:00 – 12:25 | Flash talks (2 minutes / 1 slide per talk) #49 Sebastian Aland, #51 Raul Aparicio Yuste, #53Natalia Baranova, #55 Catherine Villard, #57 Andrea Disanza, #59 Jaime Fernandez Sobaberas #61 Carolin Gierse, #63 Xiangfu Guo, #65 Saurabh Kaushik and #69 Jesus Lopz Gay Orts |
12:25 – 13:25 | Lunch |
13:25 – 14:25 | Panel Discussion – ChatGPT or Family and science discussion |
14:25 – 17:25 | Session 3 Chair: Carolina Tropini – The University of British Columbia, Canada |
14:25 – 14:55 | Sub-surface activities: the role of the cortical microtubule cytoskeleton in regulating plant cell growth and division Bela Mulder – AMOLF, Netherlands |
14:55 – 15:10 | ERK activation waves are key drivers in the mechanical cell competition that leads to collective onslaught of bacterially-infected cells Lara Hundsdorfer – University of Tübingen, Germany |
15:10 – 15:25 | Bacterial adhesion on the apical cell surface modifies the traction force field on the basal side through a new actomyosin structure, called ancreopodia Daria Bonazzi – Institut Pasteur, France |
15:25- 15:55 | Coffee Break and Meet the speakers |
15:55 – 16:25 | Multiciliated cells use filopodia to probe tissue mechanics during epithelial integration in vivo Jakub Sedzinski – Novo Nordisk Foundation Center for Stem Cell Medicine, reNEW, Denmark |
16:25 – 16:40 | Dual roles of β-catenin in signaling and cell-cell junction maintenance in the intestinal epithelium Andrew Clark – University of Stuttgart, Germany |
16:40 – 16:55 | The stability of Arp2/3 nucleated actin filaments LuYan Cao – The Francis Crick Institute, United Kingdom |
16:55 – 17:25 | Cellular Biophysics of Membranes Remodeling and Rupture – Lessons from NETosis Hawa Racine Thiam – Stanford University, USA (Remote speaker) |
17:25 – 17:55 | Flash talks (2 minutes / 1 slide per talk) #71 Xinwen Miao, #73 Alexander Dulebo, #75 Priyanka Roy, #77 Jan Sabo, #79 Gautham Hari Sankara Narayana, #81 Lan Jiang, #83 Oscar Stassen, #85 Joseph Vermeil, #87 Hannes Vogler, #89 Arash Yahyazadeh Shourabi and #91 Andrew Zhao |
17:55 – 19:25 | Poster Session 1 (odd numbers) |
19:25 – 20:25 | Dinner in Canteen |
20:25 – 21:30 | Drinks in ATC Roof top lounge |
Time (Europe/Berlin) | Speaker |
---|---|
09:00 – 12:00 | Session 4 Chair: Jakub Sedzinski – Novo Nordisk Foundation Center for Stem Cell Medicine, reNEW, Denmark |
09:00 – 09:30 | Molecular mechanobiology of the extracellular matrix Viola Vogel – ETH Zürich, Switzerland |
09:30 – 09:45 | Polarity-driven three-dimensional spontaneous rotation of a cell doublet Quentin Vagne – University of Geneva, Switzerland |
09:45 – 10:15 | Mechanobiology of tight junctions Sandra Citi – University of Geneva, Switzerland Not available on demand |
10:15 – 10:45 | Coffee Break and Meet the speakers |
10:45 – 11:00 | Interacting systems for complex cell wall patterns with special functions Eva Deinum – Wageningen University & Research, The Netherlands |
11:00 – 11:15 | Membrane reshaping across the tree of life Felix Frey – Institute of Science and Technology Austria, Austria |
11:15 – 11:30 | Modelling macropinocytic cup formation and closure informed by lattice light sheet microscopy data Judith Lutton – University of Warwick, United Kingdom |
11:30 – 12:00 | Inoviruses in the gut microbiota: release without bacterial lysis Carolina Tropini – The University of British Columbia, Canada |
12:00 – 12:25 | Flash talks (2 minutes / 1 slide per talk) #50 Luca Andronico, #52 Bin Qu, #54 Golnar Kolahgar, #56 Srishti Dar, #58 Jenna Elliott, #60 Sherman Foo, #62 David Gomez, #64 Kyojiro N. Ikeda, #66 Mengya Kong and #68 Jia Hui Li |
12:25 – 13:25 | Lunch |
13:25 – 16:55 | Session 5 Chair: Peter Bieling – Max Planck Institute of Molecular Physiology, Germany |
13:25 – 13:55 | The skin of a living cell: a mechanoresponsive membrane Satyajit Mayor – National Centre for Biological Sciences, India |
13:55 – 14:10 | Cytoskeleton-mediated spatial accommodation shapes lateral root morphogenesis Dorothee Stöckle – University of Zurich, Switzerland |
14:10 – 14:25 | Mechanisms and mechanics at the cell surface driving epithelial tube formation Matteo Rauzi – University Côte d’Azur, CNRS, Inserm, iBV, Nice, France |
14:25 – 14:55 | Bacteria mechanosense surfaces to guide motility and biofilm formation Alexandre Persat – EPFL, Switzerland |
14:55 – 15:25 | Coffee Break and Meet the speakers |
15:25 – 15:55 | The evolutionary mechanics of microbial morphogenesis Enrique Rojas – New York University, USA |
15:55 – 16:10 | Fast remodeling of surface cytoskeleton underlie phenotypic switches in the closest relatives of animals Thibaut Brunet – Institut Pasteur, France Not available on demand |
16:10 – 16:25 | Nanoscale Membrane Topography Engineering: in cells, in vitro and in between. Wenting Zhao – Nanyang Technological University, Singapore |
16:25 – 16:55 | Interplay between cell surface mechanics and contact-dependent signaling Anna Erzberger – EMBL Heidelberg, Germany |
16:55 – 17:20 | Flash talks (2 minutes / 1 slide per talk) #72 Marie Muenkel, #74 Nicolas Roby, #76 Francois Fagotto, #78 Julio Cesar Sanchez Rendon, #80 Annika Saß, #82 Vui Yin Seow, #84 Abdul Basith Tanari, #86 Filipe Vicente, #88 Steve Caplan and #90 Cheng‑han Yu |
17:20 – 18:50 | Poster Session 2 (even numbers) |
18:50 – 20:20 | Conference Dinner |
20:20 – 23:00 | Conference Party |
Time (Europe/Berlin) | Speaker |
---|---|
09:15 – 14:15 | Session 6 Chair: Anna Erzberger – EMBL Heidelberg, Germany and Ewa Paluch – University of Cambridge, UK |
09:15 – 09:45 | More than the sum: How does a composite interface govern function at the cell surface? Alba Diz-Muñoz – EMBL Heidelberg, Germany Not available on demand |
09:45 – 10:00 | PPP2R1A Regulates Migration Persistence through the NHSL1-containing WAVE Shell Complex Yanan Wang – École Polytechnique, France |
10:00 – 10:15 | Chitosan-glycerol blended micro-structured membranes for the enhancement of peripheral nerve regeneration Luca Scaccini – Scuola Normale Superiore, Italy |
10:15 – 10:30 | Organic semiconductors for modulation of mechano-sensitive channels in MDCK cells Vanessa Spagnolo – Istituto Italiano di Tecnologia, Italy |
10:30 – 10:45 | Staying in touch: septate junctions and epithelial sampling in the Drosophila crop Jason Millington – Stanford University, United States of America |
10:45 – 11:15 | Coffee Break and Meet the speakers |
11:15 – 11:45 | The final cut: ESCRT-III in cell division from archaea to eukaryotes Buzz Baum – MRC Laboratory of Molecular Biology, UK |
11:45 – 12:00 | “Cracking” the gut epithelium: junctional rupture at the interface of two different cell types Justine Creff – Molecular, Cellular and Developmental Biology, France |
12:00 – 13:00 | Lunch |
13:00 – 13:30 | Coordinating morphogenetic events: supracellular actomyosin cables as mechanical insulators Katja Röper – MRC Laboratory of Molecular Biology, UK |
13:30 – 13:45 | Hechtian strands. The threads for mechanosensing in plant cells? Denise Arico – Laboratoire de Recherche en Sciences Végétales, Université de Toulouse, CNRS. Laboratoire Reproduction et Développement des Plantes, ENS-Lyon, INRAe, France |
13:45 – 14:15 | The molecular mechanism of force feedback in lamellipodial actin networks Dyche Mullins – University of California, San Francisco, USA |
14:15 – 14:30 | Closing Remarks and Poster Prize |
14:30 – 14:45 | Departures |
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Conference shuttle bus schedule
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Hello | Hallo |
Goodbye | Auf Wiedersehen |
Good morning | Guten Morgen |
Good afternoon | Guten Tag |
Good evening | Guten Abend |
Good night | Gute Nacht |
I’m sorry | Tut mir leid |
Excuse me… | Entschuldigen Sie |
How are you? | Wie gehts? |
I’m fine thanks. And you? | Mir geht es gut , danke, und dir/Ihnen? |
What is your name | Wie heisst du? Wie heissen Sie? |
My name is | Ich heisse |
Do you speak English | Sprechen Sie Englisch? |
I don’t understand | Ich verstehe nicht |
Please speak more slowly | Können Sie bitte langsamer sprechen |
Thank you | Dankeschön |
Where is the toilet? | Wo ist die Toilette? |
Please call me a taxi | Bitte rufen Sie mir ein Taxi |
How do I get to….? | Wie komme ich zum/zur…..? |
A beer/two beers please | Ein Bier/zwei Bier bitte |
A glass of red/white wine please | Ein Glas Rot/Weisswein bitte |
The menu, please | Die Speisekarte, bitte |
Is there a local speciality? | Gibt es eine Spezialität aus dieser Gegend? |
I’m Vegetarian | Ich bin Vegetarier |
It was delicious | Es war hervorragend |
The bill, please | Die Rechnung, bitte |
I have a headache | Ich habe Kopfschmerzen |
I have a sore throat | Ich habe Halsschmerzen |
My stomach hurts | Ich habe Magenschmerzen |
I’m allergic to | Ich bin allergisch gegen |
I need a doctor who speaks English | Gibt es einen Arzt, der Englisch spricht? |
Where is the nearest COVID-19 test centre? | Wo ist das nächste COVID-19 Testzentrum? |
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Bronze sponsor
Event sponsor
Molecular Machines & Industries (MMI)
Media partners
EMBO Journal, an EMBO Press journal
FEBS Letters, a FEBS Press journal
International Union of Biochemistry and Molecular Biology
Journal of Cell Science, a The Company of Biologists journal
Open Biology, a Royal Society journal
Bio Essays, a Wiley Online Library
Advanced Biology, a Wiley Online Library
Sponsorship opportunities
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EMBO | EMBL Symposia promote scientific communication and collaboration in the European research area. They provide scientists with a platform to discuss and exchange ideas on forward-looking topics and new developments in the life sciences.
Topics emphasise upcoming developments and the interdisciplinary nature of related fields. Jointly funded and organised by EMBO and EMBL – and complementary to their respective courses, workshops, and conference programmes – the symposia promote scientific communication and collaboration.
All symposia are held in the EMBL Advanced Training Centre (ATC) in Heidelberg, Germany, or virtually.
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Date: 12 - 15 Jun 2023
Location: EMBL Heidelberg and Virtual
Venue: EMBL Advanced Training Centre
Deadline(s):
Abstract submission: Closed
Registration (On-site): Closed
Registration (Virtual): Closed
Organisers:
Contact: Maria Bacadare