Guillaume Salbreux
University of Geneva
Switzerland
EMBO | EMBL Symposium
This conference will take place at EMBL Heidelberg, with the option to attend virtually.
The building blocks of life – macromolecules, cells, tissues, and organs – act on each other via physical forces. This interplay of physical forces between the units of life gives rise to complex behaviour — enables motility, transport, growth, division, response to environmental cues, and allows the exertion of forces on the environment, bridging biological scales. The alteration of forces and mechanical properties is associated with inflammation, cancer, and ageing.
This comprehensive symposium will study the interplay of the physical forces — the mechanics — between the fundamental building blocks of life, from molecules to organs. It will cover how these physical forces enable development and how they are altered in disease. We will cover the physical mechanisms of the major components of the animal cell and its environment, including cell membranes, cytoskeleton, the nucleus, and the extracellular matrix. It will focus on the role of mechanical forces in both development and disease, engaging clinicians, cell and developmental biologists, and physical and material scientists, from in silico to in vitro and to in vivo studies. We will include state-of-the-art technological applications that rely on the knowledge and use of mechanical forces for biotechnological and healthcare purposes.
“Very well organized conference. High-level talks. When you see an interesting topic for your research field and if it’s organized by EMBL: Don’t hesitate, go and enjoy!” – Xiuyu Wang, Université de Paris, France
“This conference served as great platform for me to showcase my work and gain useful
comments and suggestions from the experts in my field. I benefitted especially from the
conference being mechanobiology-focused but not too narrow in its scope in that it also traversed multiple scales as well development and diseased conditions. This helped in networking with my peers and gaining crucial insight via expert talks. I am already looking forward to the next edition of this meeting.” – Abhishek Mukherjee, National Institutes of Health, USA
“As an early-stage PhD student, I have had a fantastic experience at this conference. It was an incredible opportunity to develop connections and hear about the innovative and creative research being conducted across the mechanobiology community.” – Rachel Mckeown, University of Cambridge, UK
University of Geneva
Switzerland
University of California, San Francisco
USA
University of Copenhagen
Denmark
Michigan State University
USA
Dresden University of Technology
Germany
Dresden University of Technology
Germany
The Francis Crick Institute
UK
The University of Chicago
USA
Heidelberg Institute for Theoretical Studies
Germany
Institut Pasteur
France
National University of Singapore
Singapore
Institut Curie
France
Kanazawa University
Japan
The University of New South Wales
Australia
The Francis Crick Institute
UK
Columbia University
USA
Ruđer Bošković Institute
Croatia
Friedrich Miescher Institute for Biomedical Research
Switzerland
EMBL Heidelberg
Germany
The Rockefeller University
USA
Institute of Science and Technology
Austria
Institute of Bioengineering of Catalonia
Spain
EMBL Heidelberg
Germany
Are you on social media? Post using #EESMechanobiology and don’t forget to tag @EMBLEvents
Time (Europe/Berlin) | Speaker |
---|---|
12:00 – 13:30 | Registration and light refreshments |
13:30 – 13:45 | Opening remarks |
13:45 – 14:45 | Keynote speaker: Interplay between inflammation, anti-tumor immunity and tissue tension Valerie Weaver – University of California, San Francisco, USA Not available on demand |
14:45 – 17:30 | Session 1 Chairs: Nicoletta Petridou – EMBL Heidelberg, Germany Alberto Elosegui Artola – The Francis Crick Institute, UK |
14:45 – 15:15 | Epithelial folding irreversibility is controlled by elastoplastic transition via mechanosensitive actin bracket formation Satoru Okuda – Kanazawa University, Japan Not available on demand |
15:15 – 15:30 | Single-cell physical phenotyping of mechanically dissociated tissue biopsies for fast diagnostic assessment Marketa Kubankova – Max Planck Institute for the Science of Light / Max-Planck-Zentrum für Physik und Medizin, Germany |
15:30 – 15:45 | A mechanochemical model for symmetry breaking in regenerating Hydra spheroids Sera Weevers – Friedrich Miescher Institute for Biomedical Research, Switzerland |
15:45 – 16:30 | Coffee break and meet the speakers |
16:30 – 17:00 | Mechanobiology of chromosomal instability in cancer Iva Tolić – Ruđer Bošković Institute, Croatia |
17:00 – 17:15 | Zebrafish trunk neural crest: an in vivo model to understand collective migration under physiological mechanical compression Elena Scarpa – University of Cambridge, United Kingdom |
17:15 – 17:30 | Stress fluctuation as a regulator of mechanical competition in epithelial cell Lucas Anger – Institut Jacques Monod, France |
17:30 – 18:30 | Poster sneak peek |
18:30 – 20:00 | Dinner in EMBL Canteen |
20:00 – 21:15 | After dinner drinks in ATC Rooftop lounge |
Time (Europe/Berlin) | Speaker |
---|---|
09:30 – 12:30 | Session 2 Chairs: Prisca Liberali – Friedrich Miescher Institute for Biomedical Research, Switzerland Satoru Okuda – Kanazawa University, Japan |
09:30 – 10:00 | Multiscale mechanics of organ morphogenesis Rashmi Priya – The Francis Crick Institute, UK Not available on demand |
10:00 – 10:15 | You are not encoded: a biological theory of form Alan Rodrigues – Rockefeller University, United States of America Not available on demand |
10:15 – 10:30 | Tissue-scale mechanics control stem cell fate and positioning during epithelial development Clementine Villeneuve – Max Planck Institute for Molecular Biomedicine, Germany |
10:30 – 11:00 | Coffee break and meet the speakers |
11:00 – 11:30 | Cell Shape Sensing in Immune Cells Ana-Maria Lennon-Duménil – Institut Curie, France |
11:30 – 11:45 | Extracellular matrix flow guides emergent in-vitro epithelial organization Abdel Rahman Abdel Fattah – CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Austria |
11:45 – 12:00 | Spatial mechano-transcriptomics of mouse embryogenesis Adrien Hallou – University of Oxford, United Kingdom |
12:00 – 12:30 | Form and function: uterine 3D structure-function relationships in early pregnancy Ripla Arora – Michigan State University, USA |
12:30 – 14:00 | Lunch and meet the editors |
13:00 – 13:45 | Optional: The World of Molecular Biology Exhibition at the Imaging Center (Max 20 participants) |
14:00 – 16:30 | Session 3 Chairs: Amy Shyer – The Rockefeller University, USA Prisca Liberali – Friedrich Miescher Institute for Biomedical Research, Switzerland |
14:00 – 14:30 | The many roles of mechanics in shaping organisms Otger Campàs – TU Dresden , Germany |
14:30 – 14:45 | Dividing cells: a minimal model for membrane constriction during cytokinesis Ivan Palaia – Institute of Science and Technology Austria, Austria |
14:45 – 15:00 | Mechanical induction of bicephalous morphogenesis in Hydra Yamini Ravichandran – University of Geneva, Switzerland |
15:00 – 15:30 | Coffee break and meet the speakers |
15:30 – 16:00 | ERK-mediated mechanical feedback for self-organized tissue patterning Tsuyoshi Hirashima – National University of Singapore, Singapore |
16:00 – 16:15 | Local decrease in cell wall mechanical stress as a possible trigger for cell splitting in Staphylococcus aureus Sheila Hoshyaripour – Friedrich Schiller University Jena, Germany |
16:15 – 16:30 | Mechanisms of mechanical compartmentalisation in intestinal organoids Clément Hallopeau – Institute for Bioengineering of Catalonia (IBEC), Spain |
16:30 – 17:00 | Flash talks (2 min each) #43 Roberto Amadio, #49 Matthew Bovyn, #55 John Robert Davis, #57 Bipasha Dey, #65 Clara Gordillo Pi, #77 Chrystian Junqueira Alves, #99 Markus Mukenhirn, #101 Irène Nagle, #115 Magdalena Schindler, #125 Yingyu Sun, #127 Stefania Tavano |
17:00 – 18:30 | Poster Session 1 (odd numbers) |
18:30 – 20:00 | Dinner in EMBL Canteen |
20:00 – 21:30 | After dinner drinks in ATC Rooftop lounge |
Time (Europe/Berlin) | Speaker |
---|---|
09:30 – 12:30 | Session 4 Chairs: Xavier Trepat – Institute of Bioengineering of Catalonia, Spain Rashmi Priya – The Francis Crick Institute, UK |
09:30 – 10:00 | Force sensing via ion channels in melanoma cells Kate Poole – The University of New South Wales, Australia |
10:00 – 10:15 | Lipid droplet segregation rigidifies embryo interior to dampen stress-induced flows and ensure stable tissue deformation during gastrulation Sameer Thukral – RIKEN Biosystems Dynamics Research, Japan |
10:15 – 10:30 | Mechanochemical coupling during intestinal crypt morphogenesis Laura Capolupo – Friedrich Miescher Institute for Biomedical Research, Switzerland |
10:30 – 11:00 | Coffee break and meet the speakers |
11:00 – 11:30 | Physical forces emerging from and for tissue morphogenesis Elias Barriga – TU Dresden, Germany |
11:30 – 11:45 | Increased intraluminal pressure in liver disease changes hepatocyte polarity and function Carlotta Mayer – Max Planck Institute of Molecular Cell Biology and Genetics, Germany |
11:45 – 12:00 | Mechanosensitive cell shape transition underlying epithelial tissue spreading Naoya Hino – Institute of Science and Technology Austria, Austria |
12:00 – 12:30 | Mechanical feedback during embryonic self-organization Jerome Gros – Institut Pasteur, France |
12:30 – 14:00 | Lunch and meet the editors |
13:00 – 13:45 | Optional: The World of Molecular Biology Exhibition at the Imaging Center (Max 20 participants) |
14:00 – 17:00 | Session 5 Chairs: Elias Barriga – Instituto Gulbenkian De Ciência, Portugal Ana-Maria Lennon-Duménil – Institut Curie, France |
14:00 – 14:30 | The role of the ECM viscoelasticity in development and disease Alberto Elosegui Artola – The Francis Crick Institute, UK Not available on demand |
14:30 – 14:45 | Histone serotonylation mediates collective migration via mechanics in vivo Joana Saraiva – Instituto Gulbenkian Ciência, Portugal |
14:45 – 15:00 | The role of Piezo1-mediated mechanosensing in natural killer cells and T cells Bin Qu – Saarland University,Germany |
15:00 – 15:30 | Coffee break and meet the speakers |
15:30 – 16:00 | How tissues convert physical forces into chemical cues – directly: protein mechanoradicals Frauke Gräter – Heidelberg Institute for Theoretical Science, Germany |
16:00 – 16:15 | Pattern analysis and emergence in axolotl limb growth Ester Comellas – Universitat Politècnica de Catalunya, Spain |
16:15 – 16:30 | Tissue architecture as a regulator of the length-scales and time-scales of morphogen signalling Camilla Autorino – EMBL Heidelberg, Germany |
16:30 – 17:00 | A slingshot through time: reconstituting the first steps of mammalian embryo development with stem cells Mijo Simunovic – Columbia University, USA |
17:00 – 17:30 | Flash talks (2 min each) #48 Arthur Boutillon, #52 Denis Krndija, #54 Jean-François Darrigrand, #66 Valeriia Grudtsyna, #72 Alejandro Clemente, #96 Carl Modes, #112 Sirio Dupont, #138 Tom Schultheiss |
17:30 – 19:00 | Poster Session 2 (even numbers) |
19:00 – 20:30 | Conference Dinner in EMBL Canteen |
20:30 – 23:00 | Conference Party |
Time (Europe/Berlin) | Speaker |
---|---|
09:30 – 13:10 | Session 6: Chairs: Anđela Šarić – Institute of Science and Technology, Austria Nicoletta Petridou – EMBL Heidelberg, Germany |
09:30 – 10:00 | Control of cell shape and proliferation in epithelial tissue Margaret Gardel – The University of Chicago, USA |
10:00 – 10:15 | Morphogen transport in tissues as active porous media Diana Khoromskaia – The Francis Crick Institute, United Kingdom |
10:15 – 10:30 | A Brillouin twist for gastrulation: The dynamics of cell mechanical properties in embryonic cell populations Juan Manuel Gomez – EMBL Heidelberg, Germany |
10:30 – 11:00 | Coffee break and meet the speakers |
11:00 – 11:30 | Exploring the cellular and molecular mechanisms controlling stretch-mediated tissue expansion in vivo Mariaceleste Aragona, University of Copenhagen, Denmark Not available on demand |
11:30 – 11:45 | Mechanical profiling of intracellular compartments in embryonic cell lineages Santiago Ortiz – Institute of Photonic Sciences, Spain |
11:45 – 12:00 | Topographies of lipid membranes are biophysical regulators for the spatial organization of liquid protein condensates Katja Zieske – Max Planck Institute for the Science of Light, Germany Not available on demand |
12:00 – 13:00 | Keynote speaker: active surfaces and biological morphogenesis Guillaume Salbreux – University of Geneva, Switzerland |
13:00 – 13:10 | Closing remarks and poster prize announcements |
13:10 | Packed lunch and departure |
On-site registration fees include admission, conference materials, meals and coffee breaks. Participants are expected to book and pay their own accommodation and travel expenses.
Virtual registration fees include access to all of the talks (livestreamed and on demand) and facility to submit questions.
On-site Academia | €725 |
On-site PhD Student | €675 |
On-site Industry | €925 |
On-site Journal Editor | €300 |
Virtual Academia | €225 |
Virtual PhD Student | €175 |
Virtual Industry | €275 |
* Editors from scientific journals are allowed to attend at a reduced rate, but asked to contribute to the conference in return by taking part in ‘meet the editors’ sessions or other planned activities within the programme.
A letter to support your visa application will be issued, on request, once payment of the registration fee is confirmed. We recommend that you book your visa appointment as soon as possible, to avoid any delay with your visa application.
Accredited journalists may be eligible to register for complimentary press registration. Registrants may be required to provide accreditation or equivalent proof of press membership after registration. Please contact Maria Bacadare for more information. Please note that we do not offer complimentary registrations for editors of scientific journals.
Registration will be on a first come, first served basis. Your place can only be confirmed after payment of the registration fee. If you are added to our waiting list, please consider taking advantage of our offerings to participate virtually.
On-site participants: Types of payments accepted are international bank transfers and credit card payments.
Virtual participants: We are only able to accept card payments. In exceptional cases we can accept bank transfers. Please contact events@embl.de for details.
Only participants registering to attend the on-site event are eligible to submit an abstract. Abstracts will not be accepted from virtual participants.
After registration you can submit your abstract via a separate link that will be provided in the email confirmation. Alternatively, you can access the link on the confirmation page directly after registering. The same login credentials are used for both processes.
Please note:
Abstract body: The limit of 2000 characters refers to manually typed text and excludes spaces. If an error occurs try using a different web browser (preferably Google Chrome or Mozilla Firefox).
If you copy-paste the text into the form, hidden formatting might still be included which may cause the text to exceed the 2,000 character limit resulting in an error message. We recommend you clear all formatting before pasting in the text.
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Title: The title should not exceed 20 words. Only the first word of the title should start with a capital letter and the rest should be lowercase.
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Kindly mark only one author in the role of First Author and please don’t forget to indicate who will be the Presenter.
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Presentation types: When submitting your abstract, you can apply for an oral or poster presentation. A selection process will take place with the results announced 2-3 weeks after the abstract submission deadline.
For detailed instructions on how to submit a conference abstract, follow the instructions provided in this video.
Please check our FAQs pages for further information on how to submit an abstract.
Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers, travel grants and childcare grants.
Your place in the meeting is only confirmed by paying the registration fee, which is mandatory even when receiving a fee waiver.
The fee waiver will cover the registration sum that you have paid to attend the course or conference.
The travel grant will cover the cost of travel to an on-site event (airfare, train, bus, taxi, accommodation, visa, and/or registration fees*) and is provided up to specified caps which are normally as follows:
–up to €400 for participants travelling to an EMBL Conference or EMBO|EMBL Symposium from within Europe.
–up to €1000 for participants travelling to an EMBL Conference or EMBO|EMBL Symposium from outside Europe.
–up to €500 for any participant travelling to an EMBO Workshop.
–up to €1000 for any participant working in Chile, India, Singapore or Taiwan travelling to an EMBO Workshop.
–up to €700 for any participant working in Croatia, Czech Republic, Estonia, Greece, Hungary, Italy, Lithuania, Luxembourg, Poland, Slovenia, and Turkey travelling to an EMBO Workshop.
*Registration fees are only covered for EMBO Workshops
The organisers may reduce the grant cap to accommodate more participants. Recipients will be notified of their travel cap amount when they are informed of the outcome of their application. Original receipts must be provided with your signature for all costs incurred within two months of completion of travel. Scanned copies cannot be accepted.
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On-site participants
You may apply for financial assistance when submitting your abstract. In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career. Application for financial support will not affect the outcome of your registration application.
Virtual participants
If you are attending virtually, you can apply for financial assistance in the submission portal by the abstract deadline. Read the instructions on how to apply for financial assistance. Only submissions for financial assistance will be accepted. Presentation abstracts cannot be submitted here and will be declined.
In your application you will be asked to summarise your current work, answer questions regarding why your lab cannot fund your attendance, and how your attendance will make a difference to your career. Application for financial support will not affect the outcome of your registration application.
The scientific organisers will select the recipients of all financial assistance during the abstract selection process. Results will be announced approximately 6 – 8 weeks before the event start date, however for some events this may be delayed. Selection results do not impact your admission to the meeting. Selection for registration fee waivers and travel grants is based on scientific merit, your current work or study location, the reasons for needing financial support, and the impact this event will have on your career.
Childcare grants will be allocated in the same timeframe (6-8 weeks before the event start date). Please note that priority will be given to early-stage researchers.
Costs will be reimbursed after the meeting only once a reimbursement form and original receipts (from travel costs) have been received.
View our list of external funding opportunities and information on attending a conference as an event reporter.
For further information about financial assistance please refer to the FAQ page.
Accommodation is not included in the conference registration fee.
As further changes in our events are possible, you should book flights, trains and hotels with flexible options and favourable cancellation conditions.
The hotels below have rooms on hold for participants until 18 March 2024, in some cases at special rates. Please email the hotel directly, quoting the booking code EES24-03 to confirm the exact price of the room.
For travel information, please see here.
If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn ‘Event Ticket’ (called the ‘Veranstaltungsticket’ in German). This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km. You need to provide proof of your event attendance when purchasing the ticket.
For more information in English see here or in German see here.
You can book your ticket here.
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The bus stops for this conference are:
Conference shuttle bus schedule
View Conference shuttle bus stops and hotels in a larger map. Please note that not every bus stop will be used for every event.
Address: EMBL, Meyerhofstraße 1, 69117 Heidelberg, Germany.
For more information about accommodation and travel, please refer to the FAQ page.
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A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing.
During the event, we provide conference shuttle buses to and from EMBL. In addition, there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time. Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page.
Hello | Hallo |
Goodbye | Auf Wiedersehen (formal) Tschüss (informal) |
Good morning | Guten Morgen |
Good afternoon | Guten Tag |
Good evening | Guten Abend |
Good night | Gute Nacht |
I’m sorry | Es tut mir leid |
Excuse me… | Entschuldigen Sie |
How are you? | Wie gehts? |
I’m fine thanks. And you? | Mir geht es gut , danke. Und Dir/Ihnen? |
What is your name | Wie heißen Sie? (formal) Wie heißt du? (informal) |
My name is.. | Ich heiße.. |
Do you speak English | Sprechen Sie englisch? |
I don’t understand | Ich verstehe nicht |
Please speak more slowly | Können Sie bitte langsamer sprechen |
Thank you | Dankeschön |
Where is the toilet? | Wo ist die Toilette? |
Please call me a taxi | Bitte rufen Sie mir ein Taxi |
How do I get to….? | Wie komme ich zum/zur…..? |
A beer/two beers please | Ein Bier/zwei Bier bitte |
A glass of red/white wine please | Ein Glas Rot/Weißwein bitte |
The menu, please | Die Speisekarte, bitte |
Is there a local speciality? | Gibt es eine Spezialität aus dieser Gegend? |
I’m vegetarian | Ich bin Vegetarier |
It was delicious | Es war hervorragend |
The bill, please | Die Rechnung, bitte |
I have a headache | Ich habe Kopfschmerzen |
I have a sore throat | Ich habe Halsschmerzen |
My stomach hurts | Ich habe Magenschmerzen |
I’m allergic to | Ich bin allergisch gegen |
I need a doctor who speaks English. | Ich brauche einen Arzt, der englisch spricht. |
Please note that only on-site participants are able to submit abstracts and participate in the poster sessions.
We are using an event platform for this conference. More information about the platform will be shared ahead of the conference.
Additional information can be found in our Code of Conduct.
It is important to stay healthy and move around, especially when you are attending an event virtually. We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event.
Please use the Q&A function in the event platform.
If you have any other questions, you can go to the Help Desk in the event platform. Click on ‘more’ on the top menu and click Help Desk.
The programme is planned based on the Europe/Berlin time zone, unless otherwise stated. Please take your time zone into consideration when planning your attendance.
COVID-19 information for onsite events at EMBL Heidelberg can be found in our COVID-19 FAQs.
Event sponsor
Event supporter
Media partners
EMBO Journal, an EMBO Press Journal
Development, The Company of Biologists Journal
Disease Models & Mechanisms, The Company of Biologists Journal
International Union of Biochemistry and Molecular Biology
Journal of Cell Science, The Company of Biologists Journal
Medinformatics, a Bon View Publishing journal
Open Biology, a Royal Society journal
Sponsorship opportunities
We offer a variety of event sponsoring possibilities, with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget. Discounts are available for companies sponsoring multiple events at EMBL Heidelberg. View other conferences, or contact sponsorship@embl.de for further information.
If you are interested in becoming a media partner of this event, please visit our media partnerships webpage.
EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials. One current scam campaign of which we are aware is conducted using the name ‘Judy Eastman’ (judy@gopcontact.a2hosted.com) and entails approaches to sponsors offering sponsorship opportunities on EMBL’s behalf. Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences, symposia and courses is handled by EMBL directly and is sent from an official EMBL account. EMBL does not work with any external providers on sponsorship acquisition.
Please also note that:
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EMBO | EMBL Symposia promote scientific communication and collaboration in the European research area. They provide scientists with a platform to discuss and exchange ideas on forward-looking topics and new developments in the life sciences.
Topics emphasise upcoming developments and the interdisciplinary nature of related fields. Jointly funded and organised by EMBO and EMBL – and complementary to their respective courses, workshops, and conference programmes – the symposia promote scientific communication and collaboration.
All symposia are held in the EMBL Advanced Training Centre (ATC) in Heidelberg, Germany, or virtually.
Want to let others know you’re attending this event? Take a look at our shareable media and feel free to use them in your social media channels or presentations.
Date: 15 - 18 Apr 2024
Location: EMBL Heidelberg and Virtual
Venue: EMBL Advanced Training Centre
Deadline(s):
Abstract submission: Closed
Registration (On-site): Closed
Registration (Virtual): Closed
Organisers:
Contact: Maria Bacadare