![](https://www.embl.org/about/info/course-and-conference-office/wp-content/uploads/Suzuki_Tsutomu-300x300.jpg)
Tsutomiu Suzuki
Dept. Chemistry and Biotechnology
Japan
EMBO Workshop
This conference will take place at EMBL Heidelberg, with the option to attend virtually.
Registration is not yet open for this event. If you are interested in receiving more information please register your interest.
The regulation of the transcriptome is key to cellular processes that underpin cell biology, development, and tissue function. All classes of cellular RNA are subject to post-transcriptional modification, be it by direct chemical modification, editing, or non-templated nucleotide additions. Now, in its fourth edition, ‘The epitranscriptome’ meeting first held at EMBL in 2016 (and repeated in 2018, then in 2022 as a virtual conference) was the first RNA modification-dedicated meeting with a focus on mammalian systems. It is now established that biochemical modifications of nucleotides regulate RNA metabolism, modulate cell functions and contribute to severe human diseases including cancer and metabolic disorders. Moreover, the power of single, chemically modified nucleotides to alter the electrostatic charge, base pairing, and stability of RNA molecules is exploited for clinical use of stable artificial RNA transcripts such as mRNA vaccines or synthetic small RNA molecules to increase or decrease the expression of therapeutic proteins. The 2025 meeting will highlight recent developments and focus on future aspects and current challenges in the field:
Together, these basic science discoveries have unravelled the molecular and cellular functions of RNA modifications, have provided new prospects for therapeutic manipulation and have led to a range of innovative clinical approaches. Our program will bring together field-leading experts from across the globe to provide cost-effective access to European researchers to the state-of-the-art.
“The epitranscriptome EMBL conference rapidly became a must in the field.” – Mattia Pelizzola, Istituto Italiano di Tecnologia, Italy
“The conference provided an excellent opportunity to get the latest insights in the field of epitranscriptomics, presented by the world-leading academic groups.” – Gerhard Müller, Gotham Therapeutics, New York, USA
“This conference was really good for me. I have learnt about new RNA regulatory mechanisms, especially m6A and how it’s an important target for RNA processing.” – Opeyemi Olotu, University of Turku, Finland
This event has been granted the following EMBO sustainability badge:
Dept. Chemistry and Biotechnology
Japan
Salamanca Cancer Research Center (CIC)
Spain
University of Chicago
USA
Duke University
USA
Institute of Molecular Biology (IMB) Mainz
Germany
Gurdon Institute
UK
EMBL Grenoble
France
Northwestern University
USA
Centre for Genomic Regulation (CRG)
Spain
The University of Edinburgh
UK
City of Hope
USA
University of Heidelberg
Germany
Peking University
China
University of Rochester
USA
German Cancer Research Center (DKFZ)
Germany
Dept. Chemistry and Biotechnology
Japan
Peking University
China
EMBL Heidelberg
Germany
Sponsorship opportunities
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Date: 28 - 30 Oct 2025
Location: EMBL Heidelberg and Virtual
Venue: EMBL Advanced Training Centre
Organisers:
Contact: EMBL Events