David Agard
University of California, San Francisco and Chan Zuckerberg Institute for Advanced Biological Imaging
USA
EMBO Workshop
This conference will take place at EMBL Heidelberg, with the option to attend virtually.
There is an increasing awareness that mechanistic understanding of complex cellular functions and interactions requires structural knowledge of the macromolecules involved. Recent technological advances in several disciplines nurture the development of in situ structural biology approaches, that have separately started to provide structural information on molecules within the context of intact cells in order to fully grasp how they function in their native environment. These include cryo-electron microscopy and tomography (EM/ET), mass spectrometry-based proteomics, fluorescence and super-resolution light microscopy, protein structure prediction, multi-scale computational modelling and others.
This conference aims to bring together experts and early stage researchers from the separate disciplines, as well as researchers from different fields in the Life Sciences:
“The conference was fantastic, with an amazing list of speakers. As an early career researcher, I found these events very inspirational and broadening for research opportunities later.” — Kamila Kamuda, University College London, UK
“I immensely benefited from the workshop organized by EMBL through talks of so many brilliant scientists who had explained the fast-evolving technique to capture the whole cell structure at the near-atomic resolution.” — Samar Ballabha Mohapatra, Indian Institute of Technology, India
This event has been granted the following EMBO sustainability badge:
University of California, San Francisco and Chan Zuckerberg Institute for Advanced Biological Imaging
USA
Janelia Research Campus
USA
Kanazawa University
Japan
Max Planck Institute of Biophysics
Germany
ETH Zurich
Switzerland
University of Geneva
Switzerland
University of California, San Francisco
USA
University of Geneva
Switzerland
Max Planck Institute of Biochemistry and Ludwig Maximilians University of Munich
Germany
EPFL
Switzerland
University of Groningen
Netherlands
ETH Zurich
Switzerland
University of Bristol
UK
Technical University of Munich
Germany
University of California, San Diego
USA
Wuhan University
China
Princeton University
USA
EMBL Heidelberg
Germany
University of Vienna
Austria
University of Fribourg
Switzerland
Course and Conference Team Lead
EMBL Heidelberg
Germany
Are you on social media? Post using #EMBOinsitu and don’t forget to tag @EMBLEvents
Time (Europe/Berlin) | Speaker |
12:00 – 13:30 | Registration and light refreshments |
13:30 – 13:45 | Opening remarks |
13:45 – 14:45 | Keynote lecture Exploring cell biology across scales Jennifer Lippincott-Schwartz – Janelia Research Campus, USA |
14:45 – 18:30 | Session 1: Molecular machines and macromolecular assemblies |
14:45 – 15:15 | Biomolecular interactions and structures probed in their physiological environment using site-directed spin labeling electron paramagnetic resonance Enrica Bordignon – University of Geneva. Switzerland |
15:15 – 15:30 | Selected short talk #1 |
15:30 – 15:45 | Selected short talk #2 |
15:45 – 16:00 | Selected short talk#3 |
16:00 – 16:30 | Coffee Break and Meet the speakers |
16:30 – 17:00 | Integrative modeling of compositional and conformationally heterogeneous protein assemblies Ignacia Echeverria – University of California, San Francisco, USA |
17:00 – 17:15 | Selected short talk #4 |
17:15 – 17:30 | Selected short talk #5 |
17:30 – 18:00 | How do molecular modules act in concert to generate complex cellular functions? Martin Beck – Max Plank Insitutte of Biophysics, Germany |
18:00 – 18:15 | Selected short talk#6 |
18:15 – 18:30 | Selected short talk #7 |
18:30 – 20:00 | Dinner in Canteen |
20:00 – 22:00 | Pub quiz and after dinner drinks |
Time (Europe/Berlin) | Speaker |
09:00 – 12:00 | Session 2: Novel Technologies 1: advanced imaging |
09:00 – 09:30 | Combined DNA nanotechnology with single-molecule fluorescence methods for high-resolution microscopy techniques Ralf Jungmann – Max Plank Insitutte of Biochemistry and LMU, Germany |
09:30 – 09:45 | Selected short talk #8 |
09:45 – 10:00 | Selected short talk#9 |
10:00 – 10:30 | Coffee Break and Meet the speakers |
10:30 – 11:00 | High speed in-liquid atomic force microscopy: direct visualization of proteins in action Toshio Ando – Kanazawa University, Japan |
11:00 – 11:15 | Selected short talk #10 |
11:15 – 11:30 | Selected short talk #11 |
11:30 – 12:00 | Imaging intracellular components in situ using superresolution cryo-correlative light and electron microscopy Thom Sharp – University of Bristol, UK |
12:00 – 13:30 | Vegetarian Lunch and Meet the Editors |
13:30-16:30 | Session 3: Organelles and Compartments |
13:30 – 14:00 | High throughput super-resolution microscopy reveals the biophysical principles underlying the dynamic organization of cellular organelles and protein assemblies Suliana Manley – EPL – Switzerland |
14:00 – 14:15 | Selected short talk #12 |
14:15 – 14:30 | Selected short talk #13 |
14:30 – 15:00 | Coffee Break and Meet the speakers |
15:00 – 15:30 | Deciphering the structural mechanisms governing centriole assembly using cryo-electron tomography, expansion and super-resolution microscopy Virginie Hamel – University of Geneva, Swtizerland |
15:30 – 15:45 | Selected short talk #14 |
15:45 – 16:00 | Selected short talk #15 |
16:00 – 16:30 | Flash talk session 1 |
16:30 – 18:30 | Poster Session 1 (odd numbers) |
18:30 | Free evening |
Time (Europe/Berlin) | Speaker |
09:00 – 11:45 | Session 4: Single cell systems |
09:00 – 09:30 | Visualizing the Conformation and Dynamics of FG-Nucleoporins in Live Cells Miao Yu – Wuhan University, China |
09:30 – 09:45 | Selected short talk #16 |
09:45 – 10:00 | Selected short talk #17 |
10:00 – 10:15 | Selected short talk #18 |
10:15 – 10:45 | Coffee Break and Meet the speakers |
10:45 – 11:15 | Towards cell-scale molecular simulations Siewert-Jan Marrink – University of Groningen, The Netherlands |
11:15 – 11:30 | Selected short talk #19 |
11:30 – 11:45 | Selected short talk #20 |
11:45 – 12:00 | Selected short talk #21 |
12:00 – 13:30 | Lunch (and optional: Career Session for 45 min or Job Fair) |
13:30 – 18:45 | Session 5: Cellular Interactions and multicellular systems |
13:30 – 14:00 | Structural proteomic based on limited proteolysis coupled to mass spectrometry (LiP-MS) with improved, amino acid level-resolution, to probe the mechanism of action of anti- amyloidogenic compounds in situ Tetiana Serdjuk – ETH Zurich, Switzerland |
14:00 – 14:15 | Selected short talk #22 |
14:15 – 14:30 | Selected short talk #23 |
14:30 – 15:00 | Coffee Break and Meet the speakers |
15:00 – 15:15 | Selected short talk #24 |
15:15 – 15:30 | Selected short talk #25 |
15:30 – 15:45 | Selected short talk #26 |
15:45 – 16:15 | Combining cell biology and electron microscopy, image processing and physical modeling to understand macromolecules in complex scenarios Elizabeth Villa – UCSD, USA |
16:15 – 16:45 | Flash talk session 2 |
16:45 – 18:45 | Poster Session 2 (even numbers) |
18:45 – 20:45 | Conference dinner in the canteen |
20:45 – 00:00 | Party |
Time (Europe/Berlin) | Speaker |
09:00 – 13:00 | Session 6: Novel Technologies 2: computational and data integration |
09:00 – 09:30 | Combining sequence and structure-based methods to predict the impact of protein variants with protein interaction network models of human cell biology Pedro Beltrao – ETH Zurich, Switzerland |
09:30 – 09:45 | Selected short talk #27 |
09:45 – 10:15 | Developing genetically encoded labels, integrators and recorders for high resolution imaging focusing on Electron Microscopy (EM) methods including correlative cryo-ET Felix Sigmund – Technical University of Munich, Germany |
10:15 – 10:45 | Coffee Break and Meet the speakers |
10:45 – 11:00 | Selected short talk #28 |
11:00 – 11:15 | Selected short talk #29 |
11:15 – 11:45 | Machine learning methods for computational and structural biology problems with a focus on protein structure determination by cryo-EM/ET Ellen Zhong – Princeton, USA |
11:45 – 12:45 | Keynote lecture Next generation hardware and software solutions for visual proteomics David Agard – UCSF and CZ Institute for Advanced Biological Imaging, USA |
12:45 – 13:00 | Closing Remarks and Poster Prize Announcements |
13:00 | Packed lunch and departure |
On-site registration fees include admission, conference materials, meals and coffee breaks. Participants are expected to book and pay their own accommodation and travel expenses.
Virtual registration fees include access to all of the talks (livestreamed and on demand) and facility to submit questions.
On-site Academia | €450 |
On-site PhD Student | €350 |
On-site Industry | €770 |
On-site Journal Editors* | €300 |
Virtual Academia | €200 |
Virtual PhD Student | €150 |
Virtual Industry | €275 |
* Editors from scientific journals are allowed to attend at a reduced rate, but asked to contribute to the conference in return by taking part in ‘meet the editors’ sessions or other planned activities within the programme.
A letter to support your visa application will be issued, on request, once payment of the registration fee is confirmed. We recommend that you book your visa appointment as soon as possible, to avoid any delay with your visa application.
Accredited journalists may be eligible to register for complimentary press registration. Registrants may be required to provide accreditation or equivalent proof of press membership after registration. Please contact Christopher Stocks for more information. Please note that we do not offer complimentary registrations for editors of scientific journals.
Registration will be on a first come, first served basis. Your place can only be confirmed after payment of the registration fee. If you are added to our waiting list, please consider taking advantage of our offerings to participate virtually.
On-site participants: Types of payments accepted are international bank transfers and credit card payments.
Virtual participants: We are only able to accept card payments. In exceptional cases we can accept bank transfers. Please contact events@embl.de for details.
Only participants registering to attend the on-site event are eligible to submit an abstract. Abstracts will not be accepted from virtual participants.
After registration you can submit your abstract via a separate link that will be provided in the email confirmation. Alternatively, you can access the link on the confirmation page directly after registering. The same login credentials are used for both processes.
Please note:
Abstract body: The limit of 2000 characters refers to manually typed text and excludes spaces. If an error occurs try using a different web browser (preferably Google Chrome or Mozilla Firefox).
If you copy-paste the text into the form, hidden formatting might still be included which may cause the text to exceed the 2,000 character limit resulting in an error message. We recommend you clear all formatting before pasting in the text.
If you have special symbols in your text, make sure you are using Unicode characters, otherwise these will not be recognised.
Title: The title should not exceed 20 words. Only the first word of the title should start with a capital letter and the rest should be lowercase.
Authors and affiliations: Please fill in the author’s details as requested in the online form. The compulsory fields are: First Name, Last Name, Organisation Name (Affiliation or Company), Country and Email.
Kindly mark only one author in the role of First Author and please don’t forget to indicate who will be the Presenter.
Please enter your co-authors correctly via the system by adding accounts together with their organisation/institute. Do not copy-paste them into the body of the abstract text, as they will not be indexed in the abstract book.
Presentation types: When submitting your abstract, you can apply for an oral or poster presentation. A selection process will take place with the results announced 2-3 weeks after the abstract submission deadline.
For detailed instructions on how to submit a conference abstract, follow the instructions provided in this video.
Please check our FAQs pages for further information on how to submit an abstract.
Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers, travel grants, and childcare grants.
Your place in the meeting is only confirmed by paying the registration fee, which is mandatory even when receiving a fee waiver.
The fee waiver will cover the registration sum that you have paid to attend the course or conference.
The travel grant will cover the cost of travel to an on-site event (airfare, train, bus, taxi, accommodation, visa, and/or registration fees*) and is provided up to specified caps which are normally as follows:
–up to €400 for participants travelling to an EMBL Conference or EMBO|EMBL Symposium from within Europe.
–up to €1000 for participants travelling to an EMBL Conference or EMBO|EMBL Symposium from outside Europe.
–up to €500 for any participant travelling to an EMBO Workshop.
–up to €1000 for any participant working in Chile, India, Singapore or Taiwan travelling to an EMBO Workshop.
–up to €700 for any participant working in Croatia, Czech Republic, Estonia, Greece, Hungary, Italy, Lithuania, Luxembourg, Poland, Slovenia, and Turkey travelling to an EMBO Workshop.
*Registration fees are only covered for EMBO Workshops
The organisers may reduce the grant cap to accommodate more participants. Recipients will be notified of their travel cap amount when they are informed of the outcome of their application. Original receipts must be provided with your signature for all costs incurred within two months of completion of travel. Scanned copies cannot be accepted.
There is the possibility to apply for a childcare grant to offset child care costs incurred by participants, speakers, and organisers when attending a conference.
Eligible costs include (but are not limited to) fees for a baby-sitter or child-care facility, and travel costs for a caregiver. Please note that priority will be given to early stage researchers. In order to apply for this grant, you must be registered by the abstract submission deadline. There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants.
On-site participants
You may apply for financial assistance when submitting your abstract. In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career. Application for financial support will not affect the outcome of your registration application.
Virtual participants
If you are attending virtually, you can apply for financial assistance in the submission portal by the abstract deadline. Read the instructions on how to apply for financial assistance. Only submissions for financial assistance will be accepted. Presentation abstracts cannot be submitted here and will be declined.
In your application you will be asked to summarise your current work, answer questions regarding why your lab cannot fund your attendance, and how your attendance will make a difference to your career. Application for financial support will not affect the outcome of your registration application.
The scientific organisers will select the recipients of registration fee waivers and travel grants during the motivation letter or abstract selection process. Results will be announced approximately 6 – 8 weeks before the event start date, however for some events this may be delayed. Selection results do not impact your admission to the meeting. Selection for registration fee waivers and travel grants is based on scientific merit, your current work or study location, the reasons for needing financial support, and the impact this event will have on your career.
Childcare grants will be allocated in the same timeframe (6-8 weeks before the event start date). Please note that priority will be given to early-stage researchers.
Costs will be reimbursed after the meeting only once a reimbursement form and original receipts (from travel costs) have been received.
View our list of external funding opportunities and information on attending a conference as an event reporter.
For further information about financial assistance please refer to the FAQ page.
Accommodation is not included in the conference registration fee.
The hotels below have rooms on hold for participants until 03 January 2025, in some cases at special rates. Please email the hotel directly, quoting the booking code ISS25-01 to confirm the exact price of the room
Hotel Anlage | Hotel Ibis Heidelberg | Premier Inn Heidelberg City |
B&B Hotel | Leonardo Hotel Heidelberg City Centre | Hilton Heidelberg |
Exzellenz Hotel | Meininger Heidelberg |
For travel information, please see here.
If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn ‘Event Ticket’ (called the ‘Veranstaltungsticket’ in German). This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km. You need to provide proof of your event attendance when purchasing the ticket.
For more information in English see here or in German see here.
You can book your ticket here.
Conference shuttle buses are free of charge for participants, and depart from designated bus stops near the hotels to EMBL and back, mornings and evenings.
View Conference shuttle bus stops and hotels in a larger map. Please note that not every bus stop will be used for every event.
Address: EMBL, Meyerhofstraße 1, 69117 Heidelberg, Germany.
For more information about accommodation and travel, please refer to the FAQ page.
All meals and coffee breaks are included in the registration fee. Our catering staff will prepare a wide variety of vegetarian meals, meat and fish dishes, soups, pasta, fresh fruit and vegetables, as well as a variety of desserts.
Please wear your badge at all times when serving yourself.
No food or drinks are allowed in the auditorium.
There are lockers available next to the stairs leading down into the Auditorium. You will find some of those equipped with sockets to charge your smartphone/tablet etc.
In most places the electricity is 220 volts AC (50 cycles). An adaptor and a plug that fits the German socket may be needed for your appliances/laptop (i.e. American, Japanese, etc.). A USB charging station for electronic devices is available at the registration desk.
If you are interested in purchasing EMBL merchandise (products presented in the glass display in the registration area), please email the EMBL shop to place an order or get in contact with your Course Organiser.
Kindly note the EMBL shop is only open upon request and all purchases must be made in cash (Euros only).
Please read EMBL’s COVID-19 safety policy for on-site events.
Do not smoke in any EMBL building.
Eating and drinking is prohibited in the Auditorium and all laboratories.
Do not enter any restricted areas or the laboratories unless instructed to do so.
If first aid is required …
In case of fire …
Beyond first aid…
Please remember to bring your own medication, if needed, to the conference. Note that the next pharmacy is a 4-minute drive from the EMBL, but for many medications you will be required to see a doctor to get a prescription.
Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg. In any case, the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary.
Wi-Fi is available on campus using the EMBL-Events network and the event specific password, which will be provided on site. The eduroam network (secure, worldwide roaming access service developed for the international research and education community) is also available.
‘’Lost and Found’’ items are kept at the registration desk until the end of the conference.
There are lockers available on-site to store your luggage, which require a 2 EURO coin to operate. There is another luggage room on level E0, which is free to use but remains unlocked during the conference.
There is a nursing room available in the ATC Rooftop Lounge on level A29.
During the conference, an EMBL Photographer may be taking photos. If you would not like to appear in these, please inform the photographer or a member of the Course and Conference Office.
We can help to print your boarding pass/train ticket. Please send it to events@embl.de and collect your print-outs at the registration desk.
There is a room for prayer, meditation and yoga located on level E0 behind the Auditorium. Please be respectful of others using the room.
A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing.
During the event, we provide conference shuttle buses to and from EMBL. In addition, there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time. Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page.
Hello | Hallo |
Goodbye | Auf Wiedersehen (formal) Tschüss (informal) |
Good morning | Guten Morgen |
Good afternoon | Guten Tag |
Good evening | Guten Abend |
Good night | Gute Nacht |
I’m sorry | Es tut mir leid |
Excuse me… | Entschuldigen Sie |
How are you? | Wie gehts? |
I’m fine thanks. And you? | Mir geht es gut , danke. Und Dir/Ihnen? |
What is your name | Wie heißen Sie? (formal) Wie heißt Du? (informal) |
My name is | Ich heiße… |
Do you speak English | Sprechen Sie englisch? |
I don’t understand | Ich verstehe nicht |
Please speak more slowly | Können Sie bitte langsamer sprechen |
Thank you | Dankeschön |
Where is the toilet? | Wo ist die Toilette? |
Please call me a taxi | Bitte rufen Sie mir ein Taxi |
How do I get to….? | Wie komme ich zum/zur…..? |
A beer/two beers please | Ein Bier/zwei Bier bitte |
A glass of red/white wine please | Ein Glas Rot/Weisswein bitte |
The menu, please | Die Speisekarte, bitte |
Is there a local speciality? | Gibt es eine Spezialität aus dieser Gegend? |
I’m vegetarian | Ich bin Vegetarier |
It was delicious | Es war hervorragend |
The bill, please | Die Rechnung, bitte |
I have a headache | Ich habe Kopfschmerzen |
I have a sore throat | Ich habe Halsschmerzen |
My stomach hurts | Ich habe Magenschmerzen |
I’m allergic to | Ich bin allergisch gegen |
I need a doctor who speaks English | Ich brauche einen Arzt, der englisch spricht |
Please note that only on-site participants are able to submit abstracts and participate in the poster sessions.
We are using an event platform for this conference. More information about the platform will be shared ahead of the conference.
Additional information can be found in our Code of Conduct.
It is important to stay healthy and move around, especially when you are attending an event virtually. We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event.
Please use the Q&A function in the event platform.
If you have any other questions, you can go to the Help Desk in the event platform. Click on ‘more’ on the top menu and click Help Desk.
The programme is planned based on the Europe/Berlin time zone, unless otherwise stated. Please take your time zone into consideration when planning your attendance.
Please find additional information including FAQs, terms and conditions, COVID-19 safety policy and travelling to EMBL on our Information for participants page.
COVID-19 information for on-site events at EMBL Heidelberg can be found in our COVID-19 FAQs.
Sponsorship opportunities
We offer a variety of event sponsoring possibilities, with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget. Discounts are available for companies sponsoring multiple events at EMBL Heidelberg. View other conferences, or contact sponsorship@embl.de for further information on sponsoring possibilities.
If you are interested in becoming a media partner of this event, please visit our media partnerships webpage.
EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials. One current scam campaign of which we are aware is conducted using the name ‘Judy Eastman’ (judy@gopcontact.a2hosted.com) and entails approaches to sponsors offering sponsorship opportunities on EMBL’s behalf. Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences, symposia and courses is handled by EMBL directly and is sent from an official EMBL account. EMBL does not work with any external providers on sponsorship acquisition.
Please also note that:
Suspicious communications purportedly from, for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship@embl.de.
Want to let others know you’re attending this event? Take a look at our shareable media and feel free to use them in your social media channels or presentations.
Date: 4 - 7 Feb 2025
Location: EMBL Heidelberg and Virtual
Venue: EMBL Advanced Training Centre
Deadline(s):
Abstract submission: 19 Nov 2024
Registration (On-site): 3 Jan 2025
Registration (Virtual): 21 Jan 2025
Organisers:
Contact: Chris Stocks