Proteomics in cell biology and disease mechanisms

Time (Europe/Berlin)	Session
11:00 – 12:30	Registration and light refreshments
11:15 – 12:15	Pre-conference workshop “Protein Interaction Coupling (PICO) – A Novel Platform Technology for Ultra-sensitive Detection and Quantification of Proteins, Protein Interactions, and PTMs“ by ACTOME (registration required)
12:30 – 12:45	Opening remarks
12:45 – 13:30	Keynote speaker: Using systems approaches to understand mechanisms in disease Nevan Krogan – University of California, San Francisco, USA Not available on demand
	Session 1: Cellular communication and interactions Chair: Marco Hein – Max Perutz Labs, Medical University of Vienna, Austria
13:30 – 13:55	A proteomic perspective on the removal of dying cells Maria Tanzer – Walter and Eliza Hall Institute, Australia
13:55 – 14:10	Mapping genetic determinants of phosphorylation identifies upstream signalling regulators Elise Needham – University of Cambridge, United Kingdom
14:10 – 14:25	Intercellular communication within a virus microenvironment dictates cellular resistance to secondary infections in a proximity-dependent manner James Kostas – Princeton University, United States of America
14:25 – 14:50	Flash talks Poster numbers: 37  Aljohara Alotaibi 39  Miguel Rosado 41  Christian Blum 43  Lucia Buccioli 45  German Rosano 47  Joel Christie 49  Francesca Conte 51  Miguel Cosenza Contreras 55  Matthias Fahrner 57  Joris Frenz 59  Biplab Ghosh 61  Christian Gnann 65  Nisha Hemandhar Kumar 67  Shelley Jager 71  Sonja Kabatnik 73  Hasmik Keshishian 75  Bianca Kuhn 77  Ming Tong 81  Nadja Gebert
14:50 – 15:20	Coffee Break
15:20 – 15:45	Next generation pan-cancer blood proteome profiling using proximity extension assay and mass spectrometry Mathias Uhlén – SciLifeLab, Sweden (virtual speaker)
15:45 – 16:00	Phosphoprotein dynamics of interacting tumor and T cells by HySic Kelly Stecker – Utrecht University, The Netherlands
16:00 – 16:15	Structural systems biology by crosslinking mass spectrometry and deep learning Andrea Graziadei – Fondazione Human Technopole, Italy
16:15 – 16:40	Mapping the diversity in spatiotemporal regulation of G protein-coupled receptors Ruth Huttenhain – Stanford University School of Medicine, USA
16:40 – 17:05	Flash talks Poster numbers: 83    Giorgia Massacci 85    Andreas Metousis 87    Ivan Mikicic 89    Sophia Müller-Dott 91    Marie Neu 93    Denys Oliinyk 97    Stefan Ebner 99    Benjamin Raymond 101  Hendrik Weisser 103  Valeriia Sapozhnikova 105  Felix Schneidmadel 107  Adrianna Seredynska 111  Sophia Steigerwald 113  Pranay Talla 115  Marvin Thielert 121  Katharina Waury 125  Marius Wrona
17:05 – 18:35	Poster session 1 (odd numbers) with refreshments
18:35 – 20:05	Dinner in Canteen
20:05 – 21:35	Social event

Time (Europe/Berlin)	Session
	Session 2: Proteomics technologies Chair: Ruth Huttenhain – Stanford University School of Medicine, USA
09:00 – 09:25	Narrow-window DIA for ultra-fast quantitative analysis of comprehensive proteomes with high sequencing depth Jesper V. Olsen – University of Copenhagen, Denmark
09:25 – 09:40	A nongenetic, optochemical method for proximity labeling in the live mouse brain Mikiko Takato – Kyoto University, Japan
09:40 – 09:55	Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome Clément Potel – EMBL Heidelberg, Germany
09:55 – 10:25	Coffee Break
10:25 – 10:50	Mapping nanoscale proteome landscape and beyond by highly streamlined microfluidics-based strategy Yu-Ju Chen – Academia Sinica, Taiwan
10:50 – 11:05	Advances in sensitive, high-throughput single-shot HLA-I and HLA-II immunopeptidomics Steven Carr – Broad Institute of MIT and Harvard, United States of America
11:05 – 11:20	Hydrogel-based tissue transformation methods for spatially resolved untargeted proteomics Kiryl Piatkevich – Westlake University, China
11:20 – 11:45	Advances in subcellular and cell surface proteomics using proximity and chemical labeling approaches Namrata Udeshi – Broad Institute, USA
11:45 – 13:15	Meet the speakers and Lunch
	Session 3: Hot now: Single cells and spatial proteomics Chair: Vadim Demichev – Charité, Germany
13:15 – 13:40	Spatially resolved proteogenomic profiling via deterministic barcoding in tissue Rong Fan – Yale, USA
13:40 – 13:55	Single-cell proteomics and transcriptomics of the human hematopoietic stem and progenitor hierarchy enables modelling of protein expression dynamics Benjamin Furtwängler – Copenhagen University, Denmark
13:55 – 14:10	Spatial proteomics reveals regional proteomic heterogeneity in the mouse brain upon circadian disruption Frederike Schäfer – Ludwig-Maximilians-Universität München, Germany
14:10 – 14:55	Coffee Break
14:55 – 15:20	Design of new protein functions using deep learning David Baker – University of Washington, USA (pre-recorded talk)
15:20 – 15:35	Pooled multicolor tagging for visualizing subcellular proteome dynamics Andreas Reicher – CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Austria
15:35 – 16:00	Spatial proteomics with single cell resolution to study functional heterogeneity in tumor tissues Matthias Mann – Max Planck Institute of Biochemistry, Germany
16:00	Free evening

Time (Europe/Berlin)	Session
	Session 4: Proteomics for precision medicine Chair: Namrata Udeshi – Broad Institute, USA
09:00 – 09:25	Immunoglobulins: the not to be ignored proteins in the plasma proteome Albert Heck – Utrecht University, the Netherlands
09:25 – 09:40	New proteomics approach to identify tissue leakage proteins in liquid biopsies Esperanza Fernandez – VIB, University of Ghent, Belgium
09:40 – 09:55	Systemic analysis of the pathological effects of a snake venom and of the impact of antivenom, in a murine model of envenoming Solange Maria de Toledo Serrano – Butantan Institute, Brazil
09:55 – 10:25	Coffee Break
10:25 – 10:50	Proteomic analysis of cancer internal heterogeneity Tami Geiger – Weizmann Institute of Science, Israel
10:50 – 11:05	Revealing the commonalities of monomeric and polymeric IgA1 clonal repertoires from human serum and milk with LC-MS methods Amber Rolland – Utrecht University, The Netherlands
11:05 – 11:20	Plasma immunopeptidomic profiling by ultra-high sensitive mass spectrometry Maria Wahle – Max Planck Institute of Biochemistry, Germany
11:20 – 11:45	Phamacoproteomic profiling identifies secreted markers for aberrant drug action Marcus Bantscheff – Cellzome, Heidelberg, Germany
11:45 – 12:10	Flash talks Poster numbers: 36  Rim Abderrahim 38  Constantin Ammar 40  Franziska Traube 42  Susanne Breitkopf 44  Mira Burtscher 48  Emilio Cirri 50  Miguel Cosenza Contreras 52  Alexandra Davies 54  Katrin Stuber 56  Tobias Feilen 58  Vijayalakshmi Gangadhara 60  Ursula Glocker 62  Nawal Hajj Sleiman 64  Jennifer Heck 66  Ericka Itang 68  Agnete Jensen 70  Anette Johansen 72  Sabita Kawan 74  Hasan Basri Kilic 76  Shibojyoti Lahiri 78  Mujia Li
12:10 – 13:40	Meet the speakers and Lunch
	Session 5: Computational proteomics and data analysis Chair: Maria Tanzer – Walter and Eliza Hall Institute, Australia
13:40 – 14:05	Fast and sensitive DIA proteomics and its applications Vadim Demichev – Charité, Germany
14:05 – 14:20	Tapioca: an ensemble machine learning framework for studying global protein-protein interaction network dynamics identifies NUCKS1 as a pan-herpesvirus proviral factor Tavis Reed – Princeton University, United States of America
14:20 – 14:35	Hierarchical Gaussian process models uncover the dark meltome of thermal proteome profiling experiments Cecile Le Sueur – EMBL Heidelberg, Germany
14:35 – 15:05	Coffee Break
15:05 – 15:30	Democractizing proteomics for chemists Jing Yang – National Center for Protein Sciences, China
15:30 – 15:45	Enhancing network methods for the systematic analysis of signaling from phosphoproteomics data Martin Garrido-Rodriguez – EMBL Heidelberg and Heidelberg University, Germany
15:45 – 16:10	Systematic immuno-capture of native organelles defines a spatial map of the human proteome Marco Hein – Max Perutz Labs, Medical University of Vienna, Austria
16:10 – 16:35	Flash talks Poster numbers: 80    Maximilian Maldacker 82    Barbara Kracher 86    Alina Meyer 90    Johannes Bruno Müller-Reif 92    Kendra Njo 94    Dimitris Papagiannidis 95    Iwan Parfentev 96    Kuan-Chih Peng 98    Sandra Pihlström 100  Alicia Reyes 104  Julia Schessner 106  Luisa Schwarzmüller 108  Tatiana Shamorkina 110  Bachuki Shashikadze 112  Oliver Schilling 114  Neil Taylor 116  Annika Topitsch 122  Caroline Weiss 124  Tilman Werner 126  Maximilian Zwiebel
16:35 – 18:05	Poster session 2 (even numbers) with refreshments
18:05 – 18:50	Keynote speaker: Decoding the protein dance Paola Picotti – ETH, Zurich, Switzerland Not available on demand
18:50 – 19:05	Closing Remarks and Poster Prize
19:05 – 20:35	Conference dinner
20:35 – 22:35	Conference Party

On-site registration fees include admission, conference materials, COVID-19 safety measures, meals and coffee breaks. Participants are expected to book and pay their own accommodation and travel expenses.

Virtual registration fees include access to all of the talks (livestreamed and on demand) and facility to submit questions.

On-site Academia	€710
On-site PhD Student	€610
On-site Industry	€910
Virtual Academia	€200
Virtual PhD Student	€150
Virtual Industry	€250

A letter to support your visa application will be issued, on request, once payment of the registration fee is confirmed. We recommend that you book your visa appointment as soon as possible, to avoid any delay with your visa application.

Accredited journalists may be eligible to register for complimentary press registration. Registrants may be required to provide accreditation or equivalent proof of press membership after registration. Please contact Catherine Casas for more information. Please note that we do not offer complimentary registrations for editors of scientific journals.

Confirmation and payment

Registration will be on a first come, first served basis. Your place can only be confirmed after payment of the registration fee. If you are added to our waiting list, please consider taking advantage of our offerings to participate virtually.

On-site participants: Types of payments accepted are international bank transfers and credit card payments. 

Virtual participants: We are only able to accept card payments. In exceptional cases we can accept bank transfers. Please contact Catherine Casas for details.

Abstract submission

Only participants registering to attend the on-site event are eligible to submit an abstract. Abstracts will not be accepted from virtual participants.

After registration you can submit your abstract via a separate link that will be provided in the email confirmation. Alternatively, you can access the link on the confirmation page directly after registering. The same login credentials are used for both processes.

Please note:

Abstract body: The limit of 2000 characters refers to manually typed text and excludes spaces. If an error occurs try using a different web browser (preferably Google Chrome or Mozilla Firefox).

If you copy-paste the text into the form, hidden formatting might still be included which may cause the text to exceed the 2,000 character limit resulting in an error message. We recommend you clear all formatting before pasting in the text.

If you have special symbols in your text, make sure you are using Unicode characters, otherwise these will not be recognised.

Title: The title should not exceed 20 words. Only the first word of the title should start with a capital letter and the rest should be lowercase.

Authors and affiliations: Please fill in the author’s details as requested in the online form. The compulsory fields are: First Name, Last Name, Organisation Name (Affiliation or Company), Country and Email.

Kindly mark only one author in the role of First Author and please don’t forget to indicate who will be the Presenter.

Please enter your co-authors correctly via the system by adding accounts together with their organisation/institute. Do not copy-paste them into the body of the abstract text, as they will not be indexed in the abstract book.

Presentation types: When submitting your abstract, you can apply for an oral or poster presentation. A selection process will take place with the results announced 2-3 weeks after the abstract submission deadline.

For detailed instructions on how to submit a conference abstract, follow the instructions provided in this video.

Please check our FAQs pages for further information on how to submit an abstract.

Financial assistance

Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme in the form of both registration fee waivers and travel grants. These are available for on-site participants at EMBL Conferences. We are currently working on securing funding for all virtual participants, and ask that you please apply for financial assistance for both on-site and virtual participation. 

Your place in the meeting is only confirmed by paying the registration fee, which is mandatory even when receiving a fee waiver.

Registration fee waiver

The fee waiver will cover the registration sum that you have paid to attend the course or conference.

Travel grant

The travel grant will cover the cost of travel to an on-site event (airfare, train, bus, taxi, accommodation, visa, and/or registration fees*) and is provided up to specified caps which are normally as follows:

–up to €400 for participants travelling to an EMBL Conference or EMBO|EMBL Symposium from within Europe.

–up to €1000 for participants travelling to an EMBL Conference or EMBO|EMBL Symposium from outside Europe.

–up to €500 for any participant travelling to an EMBO Workshop.

–up to €1000 for any participant working in Chile, India, Singapore or Taiwan travelling to an EMBO Workshop.

–up to €700 for any participant working in Croatia, Czech Republic, Estonia, Greece, Hungary, Italy, Lithuania, Luxembourg, Poland, Slovenia, and Turkey travelling to an EMBO Workshop.

*Registration fees are only covered for EMBO Workshops

The organisers may reduce the grant cap to accommodate more participants. Recipients will be notified of their travel cap amount when they are informed of the outcome of their application. Original receipts must be provided with your signature for all costs incurred within two months of completion of travel. Scanned copies cannot be accepted.

Application

On-site participants

You may apply for financial assistance when submitting your abstract. In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career. Application for financial support will not affect the outcome of your registration application.

Virtual participants

If you are attending virtually, you can apply for financial assistance in the submission portal by the abstract deadline. Read the instructions on how to apply for financial assistance. Only submissions for financial assistance will be accepted. Presentation abstracts cannot be submitted here and will be declined. 

In your application you will be asked to summarise your current work,  answer questions regarding why your lab cannot fund your attendance, and how your attendance will make a difference to your career. Application for financial support will not affect the outcome of your registration application.

Selection

The scientific organisers will select the recipients of all financial assistance during the abstract selection process. Results will be announced approximately 6 – 8 weeks before the event start date, however for some events this may be delayed. Selection results do not impact your admission to the meeting. Selection is based on scientific merit, your current work or study location, the reasons for needing financial support, and the impact this event will have on your career.

Reimbursement

Costs will be reimbursed after the meeting only once a reimbursement form and original receipts (from travel costs) have been received.

Further details

View our list of external funding opportunities and information on attending a conference as an event reporter.

For further information about financial assistance please refer to the FAQ page.

Accommodation is not included in the conference registration fee.

As further changes in our events are possible due to COVID-19, you should book flights, trains and hotels with flexible options and favourable cancellation conditions.

The hotels below have rooms on hold for participants until Wednesday, 27 September 2023, in some cases at special rates. Please email the hotel directly, quoting the booking code PRO23-02 to confirm the exact price of the room.

Hotel Anlage	Hotel ibis Heidelberg	Premier Inn Heidelberg City
Hotel Bayrischer Hof	ISG Hotel	Staycity Aparthotel Heidelberg
B&B Hotel	Leonardo Hotel Heidelberg City Centre	Steffi’s Hostel Heidelberg
Exzellenz Hotel	Meininger Heidelberg	Hotel Vier Jahreszeiten Heidelberg
Hotel Holländer Hof	Hotel Monpti

Conference shuttle buses

Conference shuttle buses are free of charge for participants, and depart from designated bus stops near the hotels to EMBL and back, mornings and evenings.

The bus stops for this conference are:

• Staycity Aparthotel (Speyerer Str. 7)
• Kurfürsten-Anlage (Opposite Main Train Station)
• Premier Inn (Kurfürsten-Anlage 23)
• Leonardo Hotel Heidelberg City Center (Bergheimer Str. 63)
• Neckarmünzplatz (Heidelberg Tourist Information)
• Peterskirche (Bus stop)
• ISG Hotel (Im Eichwald 19)

View Conference shuttle bus stops and hotels in a larger map. Please note that not every bus stop will be used for every event.

Further details

Address: EMBL, Meyerhofstraße 1, 69117 Heidelberg, Germany. For further information on getting to EMBL Heidelberg visit Public Transportation to the Venue. For information about accommodation and local transportation please refer to the FAQ page.

Catering

All meals and coffee breaks are included in the registration fee. Our catering staff will prepare a wide variety of vegetarian meals, meat and fish dishes, soups, pasta, fresh fruit and vegetables, as well as a variety of desserts.

Please wear your badge at all times when serving yourself.

No food or drinks are allowed in the auditorium.

Charging lockers

There are lockers available next to the stairs leading down into the Auditorium. You will find some of those equipped with sockets to charge your smartphone/tablet etc.

Electricity and charging station

In most places the electricity is 220 volts AC (50 cycles). An adaptor and a plug that fits the German socket may be needed for your appliances/laptop (i.e. American, Japanese, etc.). A USB charging station for electronic devices is available at the registration desk.

EMBL merchandise

If you are interested in purchasing an EMBL souvenir (products presented in the glass display in the registration area), please ask at the registration desk for more information.

Health and safety notes

Please read EMBL’s COVID-19 safety policy for on-site events.
Do not smoke in any EMBL building.
Eating and drinking is prohibited in the Auditorium and all laboratories.
Do not enter any restricted areas or the laboratories unless instructed to do so.

If first aid is required …

• The first aid room is located next to the ATC Registration Desk (room 10- 205).
• Dial the Emergency number 222 from any EMBL internal phone only.
• Where is the accident? What happened? How many injured?
• Emergency number 06221-387 7821 from mobile phones.
• Please report all accidents to the conference officer at the registration desk.

In case of fire …

• Press the nearest fire alarm button or the Emergency number 222 from any internal phone.
• A loud fire alarm will go off if an evacuation is required. On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points
• Do not use the lifts.

Beyond first aid…

Please remember to bring your own medication, if needed, to the conference. Note that the next pharmacy is a 4-minute drive from the EMBL, but for many medications you will be required to see a doctor to get a prescription.

Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg. In any case, the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary.

Internet

Wi-Fi is available everywhere on the premises using the EMBL-Events network and the event specific password, which will be provided on site. The eduroam network (secure, world-wide roaming access service developed for the international research and education community) is also available.

Lost and found

‘’Lost and Found’’ are kept at the registration desk until the end of the conference.

Luggage

There are lockers available on-site to store your luggage, which require a 2 EURO coin to operate. There is another luggage room on level E0, which is free to use but remains unlocked during the conference.

Nursing room

There is a nursing room available in the ATC Rooftop Lounge on level A29.

Photography

During the conference an EMBL Photographer may be taking photographs. If you would not like to appear in these, please inform the photographer or a member of the Course and Conference Office.

Printing

We can help printing your boarding passes/train ticket. Please send it to events@embl.de and collect your print-outs at the registration desk.

Room for prayer, yoga and meditation

There is a room for prayer, mediation and yoga located on level E0 behind the Auditorium. Please be respectful of other participants using the room.

Sightseeing

A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing.

Travel to and from the venue

During the event we provide conference shuttle buses to and from EMBL. In addition, there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time. Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page.

Useful German expressions

Where is the nearest Covid test centre?	Wo ist das nächste Covid-Testzentrum?
Hello	Hallo
Goodbye	Auf Wiedersehen
Good morning	Guten Morgen
Good afternoon	Guten Tag
Good evening	Guten Abend
Good night	Gute Nacht
I’m sorry	Tut mir leid
Excuse me…	Entschuldigen Sie
How are you?	Wie gehts?
I’m fine thanks. And you?	Mir geht es gut , danke, und dir/Ihnen?
What is your name	Wie heisst du? Wie heissen Sie?
My name is	Ich heisse
Do you speak English	Sprechen Sie Englisch?
I don’t understand	Ich verstehe nicht
Please speak more slowly	Können Sie bitte langsamer sprechen
Thank you	Dankeschön
Where is the toilet?	Wo ist die Toilette?
Please call me a taxi	Bitte rufen Sie mir ein Taxi
How do I get to….?	Wie komme ich zum/zur…..?
A beer/two beers please	Ein Bier/zwei Bier bitte
A glass of red/white wine please	Ein Glas Rot/Weisswein bitte
The menu, please	Die Speisekarte, bitte
Is there a local speciality?	Gibt es eine Spezialität aus dieser Gegend?
I’m Vegetarian	Ich bin Vegetarier
It was delicious	Es war hervorragend
The bill, please	Die Rechnung, bitte
I have a headache	Ich habe Kopfschmerzen
I have a sore throat	Ich habe Halsschmerzen
My stomach hurts	Ich habe Magenschmerzen
I’m allergic to	Ich bin allergisch gegen
I need a doctor who speaks English	Gibt es einen Arzt, der Englisch spricht?
Where is the nearest COVID-19 test centre?	Wo ist das nächste COVID-19 Testzentrum?

What’s included?

• Access to all the livestreamed talks
• Video library of the recorded talks during and after the event
• Facility to submit questions

Please note that only on-site participants are able to submit abstracts and participate in the poster sessions.

Event platform

We are using an event platform for this conference. More information about the platform will be shared ahead of the conference.

Guidelines

• Do not broadcast the conference to unregistered participants.
• You are encouraged to tweet and post about the event. Tweet unless the speaker specifically says otherwise, but be mindful of unpublished data. 
• Please do not capture, transmit or redistribute data presented at the meeting.

Additional information can be found in our Code of Conduct.

Health and well-being

It is important to stay healthy and move around, especially when you are attending an event virtually. We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event.

How to ask questions

Please use the Q&A function in the event platform.

If you have any other questions, you can go to the Help Desk in the event platform. Click on ‘more’ on the top menu and click Help Desk. 

Time zone

The programme is planned based on the Europe/Berlin time zone, unless otherwise stated. Please take your time zone into consideration when planning your attendance.

Please find additional information including FAQs, terms and conditions, COVID-19 safety policy and travelling to EMBL on our Information for participants page.

COVID-19 information for on-site events at EMBL Heidelberg can be found in our COVID-19 FAQs.