Vladimir Benes
EMBL Heidelberg
Germany
EMBL Course
Systems biology is a still expanding field of research aiming to understand at the molecular level how cells, tissues and organisms operate in their biological context. Among the key technologies driving this forward are next-generation sequencing and proteomics, as they provide powerful means to determine global expression levels of genes and proteins. Both fields have matured to a degree that they have now become accessible to researchers in many areas of biology.
During this course, participants will gain theoretical insight in the structure of sequencing and proteomic data, and they will receive training in data analysis for the annotation, quantification, and statistical analysis of gene and protein expression using various computational tools. In addition, training will be provided in the use of Cytoscape to derive biological insights from the integration of both data types.
This course is targeted at biologists and biochemists who are (starting to be) involved in both next-generation sequencing and mass spectrometry-based proteomics, but who are not experts in these fields.
The aim of this practical course is to provide insight in techniques that are frequently used for transcriptome and proteome analysis, and to provide hands-on experience turning primary data into information that can be used for further biological interpretation. To achieve these goals, participants will gain insight in the basic principles of gene expression analysis (RNAseq data quantification and differential expression analysis), protein identification and quantification, and they will be trained in the use of software tools to analyse sequencing and proteomic data (SearchGUI, PeptideShaker, MaxQuant). In addition, the course will provide insight in the complementarity of transcriptome and proteome data by their integrative analysis via Cytoscape.
“Besides of the amazing content provided by distinguished speakers, participants with diverse scientific backgrounds broadened our perspectives and created a nourishing scientific environment. We were able to learn key aspects of integrating omics data to our research and benefited from networking opportunities. Overall, it was a really nice experience.” – Damla Gunes, Koç University, Turkey
“The analysis and integration of transcriptome and proteome data course organized by EMBL allowed me to expand my horizons regarding the various bioinformatic tools and statistical analysis available that we can use for our transcriptome and proteomic. Highly Recommended!” – Diogo Estêvão, i3S – Institute for Research and Innovation in Health & CRIG – Cancer Research Institute
Ghent, Belfium
EMBL Heidelberg
Germany
University of Turin
Italy
University of Ghent
Belgium
German Cancer Research Centre (DKFZ)
Germany
VIB University of Ghent
Belgium
University of Ghent
Belgium
EMBL Heidelberg
Germany
University of Turin
Italy
University of Ghent
Belgium
German Cancer Research Centre (DKFZ)
Germany
VIB University of Ghent
Belgium
Course and Conference Team Lead
EMBL Heidelberg
Germany
Training Laboratory Manager
EMBL Heidelberg
Germany
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Time (Europe/Berlin) | Session | Location |
---|---|---|
08:40 – 09:00 | Bus from hotel to EMBL ATC Entrance | ISG Hotel |
09:00 – 09:15 | Arrival, welcome and safety introductions | Courtyard room |
09:15 – 11:00 | Q&A to Vladimir’s talks RNAseq part I and II Vladimir Benes – EMBL Heidelberg, Germany | Courtyard room |
11:00 – 11:30 | Coffee break | ATC Foyer |
11:30 – 12:30 | RNAseq: Reads to genes | Courtyard room |
12:30 – 13:30 | Lunch | EMBL Canteeb |
13:30 – 16:00 | Practical: From Reads to Genes | Computer Training Lab |
16:00 – 16:30 | Coffee break | ATC Foyer |
16:30 – 18:00 | Q&A on RNAseq | Computer Training Lab |
18:00 – 18:20 | Departure to ISG Hotel | ATC entrance |
18:30 – 19:30 | Dinner | ISG Hotel |
Time (Europe/Berlin) | Session | Location |
---|---|---|
08:40 – 09:00 | Bus from ISG Hotel to EMBL ATC entrance | ISG Hotel bus stop |
09:00 – 10:00 | Flash talk presentations | Computer Training Lab |
10:00 – 12:30 | Practical & theory: Differential expression analysis | Computer Training Lab |
12:30 – 13:30 | Lunch | EMBL Canteen |
13:30 – 16:00 | Lecture: Ribosome profiling Gerben Menschaert – University of Ghent, Belgium | Computer Training Lab |
16:00 – 16:30 | Coffee break | Computer Training Lab |
16:30 – 18:30 | Practical Session: Ribosome profiling Gerben Menschaert – University of Ghent, Belgium | Computer Training Lab |
18:30 – 19:30 | Pizza dinner | Rooftop lounge |
19:30 | Departure to ISG Hotel | ATC entrance |
Time (Europe/Berlin) | Session | Location |
---|---|---|
08:40 – 09:00 | Bus from ISG Hotel to EMBL ATC entrance | ISG Hotel bus stop |
09:00 – 11:00 | Introduction to Proteomics Jeroen Krijgsveld – German Cancer Research Centre (DKFZ), Germany | Computer Training Lab |
11:00 – 11:30 | Coffee break | Foyer |
11:30 – 12:30 | Lecture: Quantitative proteomics: SILAC and other MS1-based approaches Jeroen Krijgsveld – German Cancer Research Centre (DKFZ), Germany | Computer Training Lab |
12:30 – 13:30 | Lunch | EMBL Canteen |
13:30 – 15:00 | Lecture: Bioinformatics for proteomics Lennart Martens – University of Ghent, Belgium | Computer Training Lab |
15:00 – 16:00 | Q&A to Bioinformatics for proteomics Lennart Martens – University of Ghent, Belgium | Computer Training Lab |
16:00 – 16:30 | Coffee break | Computer Training Lab |
16:30 – 18:00 | Practical Session: Turning data into information-peptide and protein identification, database searching Lennart Martens – University of Ghent, Belgium with flexible coffee break | Computer Training Lab |
18:00 – 18:30 | Dinner | EMBL Canteen |
18:30 | Departure to ISG Hotel | ATC entrance |
Time (Europe/Berlin) | Session | Location |
---|---|---|
08:40 – 09:00 | Bus from ISG Hotel to EMBL ATC entrance | ISG Hotel bus stop |
09:00 – 10:00 | Lecture: Introduction to DIA proteomics data analysis Daria Fijalkowska – University of Ghent, Belgium | Computer Training Lab |
10:00 – 10:30 | Coffee break | ATC Foyer |
10:30 – 12:00 | Practical Session: DIA proteomics data analysis Daria Fijalkowska – University of Ghent, Belgium | Computer Training Lab |
12:00 – 13:00 | Lunch | EMBL Canteen |
13:00 – 14:30 | Practical Session: Quantitative proteomics data interpretation Daria Fijalkowska – University of Ghent, Belgium | Computer Training Lab |
14:30 – 16:15 | Lecture: P-values and multiple testing correction Hyungwon Choi – National University of Singapore, Singapore | Computer Training Lab |
16:15 | Free afternoon | |
16:15 | Departure to ISG Hotel and downtown | ATC entrance |
Time (Europe/Berlin) | Session | Location |
---|---|---|
08:40 – 09:00 | Bus from ISG Hotel to EMBL ATC entrance | ISG Hotel bus stop |
09:00 – 10:00 | Q&A to Bioinformatic tools for data comparison and integration John “Scooter” Morris – University of California, San Francisco, USA | Computer Training Lab |
10:00 – 10:30 | Coffee break | Computer Training Lab |
10:30 – 12:30 | Practical: Introduction to Cytoscape John “Scooter” Morris – University of California, San Francisco, USA | Computer Training Lab |
12:30 – 13:30 | Lunch | EMBL Canteen |
13:30 – 15:00 | Practical: Introduction to Cytoscape John “Scooter” Morris – University of California, San Francisco, USA | Computer Training Lab |
15:00 – 16:15 | Lecture and Practical: Enrichment analysis John “Scooter” Morris – University of California, San Francisco, USA | Computer Training Lab |
16:15 – 16:45 | Coffee break | Computer Training Lab |
16:45 – 17:45 | Application talk: Network-oriented integrative multi-omics analysis of tissues and fluids – case studies in cancer and cardiovascular diseases Hyungwon Choi – National University of Singapore, Singapore | ATC entrance |
17:45 – 18:15 | Departure to ISG Hotel and downtown | ATC entrance |
18:15 – 22:25 | Downtown dinner |
Time (Europe/Berlin) | Session | Location |
---|---|---|
08:40 – 09:00 | Bus from ISG Hotel to EMBL ATC entrance | ISG Hotel bus stop |
09:00 – 12:00 | Practical Session: Data integration John “Scooter” Morris – University of California, San Francisco, USA with flexible coffee break | Computer Training Lab |
12:00 – 13:00 | Lunch | EMBL Canteen |
13:00 – 15:00 | Practical Session: Data integration John “Scooter” Morris – University of California, San Francisco, USA | Computer Training Lab |
15:00 – 15:30 | Course wrap-up and farewell | Computer Training Lab |
15:30 | Departure to train station | ATC entrance |
The course is limited to 24 participants. For selection purposes, please note that your application will not be considered without a letter of motivation.
Registration fees include admission, course materials, meals and coffee breaks. Participants are expected to book and pay their own accommodation and travel expenses.
Academia | €750 |
PhD Student | €750 |
Industry | €1200 |
A letter to support your visa application will be issued, on request, once payment of the registration fee is confirmed. We recommend that you book your visa appointment as soon as possible, to avoid any delay with your visa application.
The registration fee should be paid only after acceptance to the course. The results will be announced approximately 2-3 weeks after the application deadline.
After you have logged in and successfully registered, you will receive an email asking you to submit your motivation letter. Click on the link provided and enter your motivation letter in the text box provided. Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering.
Instructions
Please note:
For detailed instructions, please watch our video on how to submit a course motivation letter.
For further information about registration and motivation letter submission please refer to the FAQ page.
Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers, travel grants and childcare grants.
Your place in the meeting is only confirmed by paying the registration fee, which is mandatory even when receiving a fee waiver.
The fee waiver will cover the registration sum that you have paid to attend the course.
The travel grant will cover the cost of travel (airfare, train, bus, taxi, accommodation, visa, and/or registration fees*) and is provided up to specified caps which are normally as follows:
– up to €400 for participants travelling to an EMBL Course within Europe.
– up to €1000 for participants travelling to an EMBL Course from outside Europe.
– up to €500 for any participant travelling to an EMBO Practical Course.
– up to €1000 for any participant working in Chile, India, Singapore or Taiwan travelling to an EMBO Practical Course.
– up to €700 for any participant working in Croatia, Czech Republic, Estonia, Greece, Hungary, Italy, Lithuania, Luxembourg, Poland, Slovenia, and Turkey travelling to an EMBO Practical Course.
*Registration fees are only covered for EMBO Practical Courses
The organisers may reduce the grant cap to accommodate more participants. Recipients will be notified of their travel cap amount when they are informed of the outcome of their application. Original receipts must be provided with your signature for all costs incurred within two months of completion of travel. Scanned copies cannot be accepted.
There is the possibility to apply for a childcare grant to offset child care costs incurred by participants, speakers, trainers and organisers when attending a course. Eligible costs include (but are not limited to) fees for a babysitter or child-care facility and travel costs for a caregiver. Please note that priority will be given to early-stage researchers. There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants.
Applies to selected courses only. Availability will be indicated during the abstract or motivation letter submission process.
This grant covers costs related to your attendance to the course (registration, travel and accommodation costs). The grant is restricted to PhD students and postdocs who conduct basic biomedical research.
Whether you are eligible to apply for a travel grant, depends on when you received your university entrance qualification (e.g. Abitur, A-Levels, High School Diploma, Final State Examination):
– for PhD and MD students, as well as graduates, the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course
– for postdocs, the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course
If you are attending virtually, you can apply for financial assistance in the submission portal by the abstract deadline. Read the instructions on how to apply for financial assistance. Only submissions for financial assistance will be accepted. Presentation abstracts cannot be submitted here and will be declined.
In your application you will be asked to summarise your current work, answer questions regarding why your lab cannot fund your attendance, and how your attendance will make a difference to your career. Application for financial support will not affect the outcome of your registration application.
*For some events, applications for Childcare Grants will still be done by email. Information about the grant will be sent out shortly after the abstract/motivation letter deadline. Please contact the event Conference Officer if you have any questions.
The scientific organisers will select the recipients of registration fee waivers during the participant selection process for courses. Results will be announced approximately 6 – 8 weeks before the event start date, however for some events this may be delayed. Selection results do not impact your admission to the meeting. Selection for registration fee waivers and travel grants is based on scientific merit, your current work or study location, the reasons for needing financial support, and the impact this event will have on your career.
Childcare grants will be allocated in the same timeframe (6-8 weeks before the event start date). Please note that priority will be given to early-stage researchers.
Check out this list of external funding opportunities or get more information on attending the conference as an event reporter.
For further information about financial assistance please refer to the FAQ page.
Accommodation is not included in the registration fee. Participants are expected to book and pay for their own accommodation.
A mix of single and twin rooms have been reserved for x nights from…. x … to y at the xxxx hotel. Single rooms are limited and will be available on a first come, first served basis.
After the selection process, selected participants should contact the hotel directly to make a booking with a booking code (code of your course, e.g. PQC24-01) by the deadline of …..
We recommend that all course participants stay at the dedicated hotel for the course.
For travel information, please see here.
If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn ‘Event Ticket’ (called the ‘Veranstaltungsticket’ in German). This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km. You need to provide proof of your event attendance when purchasing the ticket.
For more information in English see here or in German see here.
You can book your ticket here.
Shuttle buses will go from the ISG Hotel to EMBL and back, mornings and evenings. A bus schedule and location of the bus stops will be made available prior to the meeting.
Address: EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany
For more information about accommodation and travel, please refer to the FAQ page.
Accommodation is not included in the registration fee. Participants are expected to book and pay for their own accommodation.
A mix of single and twin rooms have been reserved for 6 nights from Saturday 3 May until Friday 9 May at the Premier Inn hotel. Single rooms are limited and will be available on a first come, first served basis.
After the selection process, selected participants should contact the hotel directly to make a booking with a booking code (PRO25-01) by the deadline of Wednesday 2 April, 2025.
We recommend that all course participants stay at the dedicated hotel for the course.
For travel information, please see here.
If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn ‘Event Ticket’ (called the ‘Veranstaltungsticket’ in German). This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km. You need to provide proof of your event attendance when purchasing the ticket.
For more information in English see here or in German see here.
You can book your ticket here.
Shuttle buses will go from the ISG Hotel to EMBL and back, mornings and evenings. A bus schedule and location of the bus stops will be made available prior to the meeting.
Address: EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany
For more information about accommodation and travel, please refer to the FAQ page.
All meals and coffee breaks are included in the registration fee. Our catering staff will prepare a wide variety of vegetarian meals, meat and fish dishes, soups, pasta, fresh fruit and vegetables, as well as a variety of desserts.
Please wear your badge at all times when serving yourself.
No food or drinks are allowed in the laboratories.
In most places the electricity is 220 volts AC (50 cycles). An adaptor and a plug that fits the German socket may be needed for your appliances/laptop (i.e. American, Japanese, etc.). A USB charging station for electronic devices is available at the registration desk..
If you are interested in purchasing EMBL merchandise (products presented in the glass display in the registration area), please email the EMBL shop to place an order or get in contact with your Course Organiser.
Kindly note the EMBL shop is only open upon request and all purchases must be made in cash (Euros only).
Please read EMBL’s COVID-19 safety policy for on-site events.
Do not smoke in any EMBL building.
Eating and drinking is prohibited in all laboratories.
Do not enter any restricted areas or the laboratories unless instructed to do so.
If first aid is required …
In case of fire …
Beyond first aid…
Please remember to bring your own medication, if needed, to the conference. Note that the next pharmacy is a 4-minute drive from the EMBL, but for many medications you will be required to see a doctor to get a prescription.
Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg. In any case, the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary.
Wi-Fi is available on campus. Log in using the EMBL-Events network and the event specific password, which will be provided on site. The eduroam network (secure, worldwide roaming access service developed for the international research and education community) is also available.
‘’Lost and Found’’ items are kept at the registration desk until the end of the conference.
There are lockers available on-site to store your luggage, which require a 2 EURO coin to operate. There is another luggage room on level E0, which is free to use but remains unlocked during the conference.
There is a nursing room available in the ATC Rooftop Lounge on level A29.
During the conference, an EMBL Photographer may be taking photos. If you would not like to appear in these, please inform the photographer or a member of the Course and Conference Office.
We can help to print your boarding pass/train ticket. Please send it to events@embl.de and collect your print-outs at the registration desk.
There is a room for prayer, meditation, and yoga located on level E0 behind the Auditorium. Please be respectful of others using the room.
A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing.
During the event, we provide conference shuttle buses to and from EMBL. In addition, there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time. Information on the shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page.
The EMBL eCampus learning platform will be used to collaborate, communicate and network with all of the course participants. All participants will receive information on how to join shortly before the course. We recommend using Chrome, Safari or Mozilla Firefox browsers for eCampus.
Zoom will be used for the live talks and Q&A sessions. More information will be provided closer to the start of the course.
While using the software during the course, please make sure you have nothing else using your bandwidth. We recommend using a wired connection.
Sponsorship opportunities
We offer a variety of event sponsoring possibilities, with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget. Discounts are available for companies sponsoring multiple events at EMBL Heidelberg. View other events, or contact sponsorship@embl.de for further information.
If you are interested in becoming a media partner of this event, please visit our media partnerships webpage.
EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials. One current scam campaign of which we are aware is conducted using the name ‘Judy Eastman’ (judy@gopcontact.a2hosted.com) and entails approaches to sponsors offering sponsorship opportunities on EMBL’s behalf. Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences, symposia and courses is handled by EMBL directly and is sent from an official EMBL account. EMBL does not work with any external providers on sponsorship acquisition.
Please also note that:
Suspicious communications purportedly from, for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship@embl.de.
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Date: 4 - 9 May 2025
Location: EMBL Heidelberg
Venue: EMBL Advanced Training Centre
Deadline(s):
Application: 9 Feb 2025
Organisers:
Contact: EMBL Events