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Plasticity in developing systems: time, space, and environment – Course and Conference Office

EMBO Practical Course

Plasticity in developing systems: time, space, and environment

Overview

Course Overview

Studying organisms in their original context and environment is one of the current grand challenges in the life sciences and a central goal of modern Developmental Biology. The interactions between organisms, and their chemical, physical and biotic environments have important consequences at the level of form, physiology and behaviour. To gain an understanding and uncover mechanistic links between these interconnected and dynamic processes, novel, interdisciplinary approaches and cutting-edge technologies are needed. The aim of this course is to expose and introduce graduate students and postdoctoral fellows to fundamental questions and challenges related to the study of how the dynamic interplay between organisms and their changing environment impacts developmental processes and evolutionary novelty. The participating students will benefit from a well-balanced curriculum with lectures and hands-on practicals. We invite external keynote speakers each day of the course, covering different topics related to how environmental factors control development, physiology, and behaviours, and emphasising developmental plasticity, timing, and metabolism. Each afternoon, EMBL groups will run lab practicals in a wide range of organisms (i.e., bacterial colonies+Dictyostelium, algae, plants, Nematostella, worms, flies, vertebrates). Most experiments will be centered around the common theme of ‘Organisms interacting with their environment’.

Audience

This course is intended for graduate students and post-doctoral fellows with a STEM background. We aim to balance the number of participants with hands-on experience and theoretical background.

Modules

  • Studying collective behaviors of soil-derived Dictyostelium and Bacilli species
  • Metabolic control of developmental timing in mouse and medaka embryos
  • Studying the role of behaviour in development of Nematostella vectensis
  • 4D imaging of development
  • Single-cell sorting of diatom symbiosis from the natural environment
  • Molecular dissection of brain pioneer cell morphogenesis in C. Elegans
  • Phenotypic plasticity of the planarian flatworms
  • Exploring animal development and evolution with synthetic biology in Drosophila Melanogaster
  • Imaging of cellular bases of root formation in the model plant Arabidopsis thaliana using a SPIM microscope
  • Biophysical properties of embryonic tissues in zebrafish

Learning outcomes

The course will provide:

1 ) an introduction to modern developmental biology questions covering a broad spectrum of developing systems

2) hands-on experiments and data analysis in a variety of model and non-model organisms.

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Please see EMBL’s COVID-19 safety policy for testing and other requirements to attend this on-site course.

Date: 24 Jul - 4 Aug 2023

Location: EMBL Heidelberg

Venue: EMBL Advanced Training Centre


Deadline(s):

Application: Closed


Organisers:

  • Alexander Aulehla
    EMBL Heidelberg, Germany

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