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Target Validation Using Genomics and Informatics – Course and Conference Office

EMBL- Wellcome Genome Campus Conference

Target Validation Using Genomics and Informatics

Overview

Bus scheduleposter listingonsite logistics information are now available for download.

Conference Overview

In association with Wellcome Genome Campus, we are pleased to announce the annual conference on Target Validation using Genomics and Informatics.

In the past few years, exceptional progress has been made in making available thousands of DNA variants that are robustly associated with clinically relevant human traits.  This is providing a rich source of molecular points for drug discovery and a deeper understanding of human biology. This meeting will highlight advances in the use of high-throughput methods and functional validation techniques that can influence the selection of new drug targets and the development of precision medicine. We will discuss the advancements and challenges of using gene editing (e.g. CRISPR) in human cells to develop validation approaches. The programme will also present recent advances in visualisation techniques, computational tools and new platforms that provide data integration and can enhance the user experience.

This meeting will bring together researchers based in academia and industry to focus on the opportunities and challenges for genomics in drug discovery. Multi-omics (e.g. genomics, proteomics, transcriptomics), epidemiology, molecular biology and computational approaches will be covered, focusing on the contributions of these methods to target validation.

Session Topics

  • Genetics
  • Case studies
  • Genome editing for target validation
  • Relevant models for target validation
  • Computational methods and analysis

Speakers

Speakers and Trainers

Keynote Speakers

Mark Daly

Institute for Molecular Medicine Finland FIMM

Finland

Edith Hessel

GSK

UK

Speakers

Jeff Barrett

Genomics plc

UK

Hans Bitter

Bluebird bio,

USA

Paolo Casale

insitro

USA

Damian Crowther

AstraZeneca

UK

Calliope Dendrou

Wellcome Trust Centre for Human Genetics

UK

Silvia Domcke

University of Washington

USA

Sandra Engle

Biogen

USA

Janna Hutz

Eisai Center for Genetics Guided Dementia Discovery

USA

Dirk Jäger

National Center for Tumor Diseases

Germany

James Lee

University of Cambridge

UK

Astrid Ruefli-Brasse

23andme

USA

Eric Shifrut

University of California, San Francisco

USA

Gosia Trynka

Wellcome Sanger Institute

UK

Robert Vries

Hubrecht Organoid Technology

The Netherlands

Scientific Organisers

Jeff Barrett

Genomics plc

UK

Sally John

Biogen

USA

Gitte Neubauer

Cellzome

Germany

Oliver Stegle

EMBL Heidelberg

Germany

Conference Organisers

Maria Mercedes Bacadare Goitia

EMBL Heidelberg

Germany

Programme

Date: 8 - 10 Dec 2019

Location: EMBL Heidelberg


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