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Protein Synthesis and Translational Control – Course and Conference Office

EMBL Conference

Protein Synthesis and Translational Control

Overview

Registered participants will receive an email with access to the virtual conference platform on Monday 30 August.

EMBL is committed to sharing research advances and sustaining scientific interaction throughout the coronavirus pandemic. We are delighted to announce that this conference is going virtual and invite you to join us online.

Conference Overview

The regulation of mRNA translation is a process required to maintain cell homeostasis, and its malfunction can lead to disease. In recent years, advances in high-throughput and microscopy methods have revealed findings that challenge hitherto established dogmas, such as extensive translation in “untranslated” regions of a transcript, pervasive initiation from non-AUG codons, heterogeneity and specialization of the ribosome or specialized roles for ‘general’ translation factors. The influence of epitranscriptomics and physical transitions in translation, or the molecular mechanisms underlying ribosome quality control are just examples where rapid progress is impacting our view of translation.

It is also now clear that the mRNA is covered with RNA binding proteins (RBPs) that control its fate, some of which have dual functions as enzymes, revealing connections with metabolism that we still need to understand. Thus, translation cannot be seen anymore as an isolated process, but as one highly connected with other steps of gene expression and finely dependent on cellular context. Advance on these aspects will be featured, as well as the role of translation regulation in diseases as diverse as cancer, metabolic or neurological disorders.

Session Topics

  • Translation initiation
  • Ribosome, elongation, termination
  • Metabolism and disease
  • RNP complexes
  • Interconnections and turnover
  • Methods and systems approaches

This conference is partnered with Cold Spring Harbor Laboratory (CSHL).

Date: 7 - 10 Sep 2021

Location: Virtual


Deadline(s):

Abstract submission: Closed

Registration: Closed


Organisers:

  • Fátima Gebauer
    Centre for Genomic Regulation (CRG)

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