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Human Ecosystems

Studying how the environment impacts human health

The Human Ecosystems Transversal Theme forms part of EMBL’s “Molecules to Ecosystems Programme”.

The theme operates across EMBL sites with the aim of leveraging EMBL’s molecular biology expertise to address some of the biggest challenges relating to human health.

Defining the impact of the environment on human disease risk is an emerging area of research which, when combined with advances in genetics, could inform new treatment interventions, precision medicine and environmental protection.

By working with experts across genomics, epidemiology, toxicology and clinical research, we aim to understand how the combined impact of the environment and genotype leads to the likelihood of disease. From human cohorts to model systems research and developing new computational methods, EMBL aims to pave the way for understanding the molecular basis of genotype and environmental interactions underlying human health.

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We want to address major challenges relating to Human Health

Enable combined environmental exposure and genetic research in human cohorts

Identify molecular biomakers of exposure affects using model systems

Leverage fundamental molecular biology research to inform gene x exposure interactions.

Generate computational tools to enable exposure research in model systems through to human cohorts.

Up-skill the next generation of human health scientists to understand genotype x environmental research.

Develop tools and services to support & enable gene x exposure research.

25 November 2024

Searching Gene x Environment in the GWAS Catalog

The GWAS Catalog The GWAS Catalog provides an archival and search service for detailed and richly-annotated data from human genome-wide association studies (GWAS). These data can be searched, browsed, visualised and downloaded on the website (https://www.ebi.ac.uk/gwas/). The Catalog includes…

11 October 2024

Barcelona Exposome Symposium: Building a Collaborative Research Community

For the first time, institutions across the Barcelona area gathered for the Barcelona Exposome Symposium, an event on the 25th September 2024 designed to promote collaboration within the growing exposome research community. The exposome is the integrated compilation of all the physical, chemical,…

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