Recent technological advances, both experimental and computational, make it possible to address key questions that will bring a quantitative, mechanistic, and molecular understanding of environmental effects on human biology. Human Ecosystems research and services at EMBL aim to arrive at a molecular understanding of how we interact with our physical, biological, and social environments to identify avenues for the mitigation and treatment of disease.
The UniProt Knowledgebase provides users with a comprehensive, high-quality and freely accessible set of protein sequences annotated with functional information. Recent evidence suggests that proteins from the saliva of blood-feeding arthropods, such as mosquitoes, lice, sandflies, bedbugs and…
The GWAS Catalog The GWAS Catalog provides an archival and search service for detailed and richly-annotated data from human genome-wide association studies (GWAS). These data can be searched, browsed, visualised and downloaded on the website (https://www.ebi.ac.uk/gwas/). The Catalog includes…
For the first time, institutions across the Barcelona area gathered for the Barcelona Exposome Symposium, an event on the 25th September 2024 designed to promote collaboration within the growing exposome research community. The exposome is the integrated compilation of all the physical, chemical,…
We are delighted to announce that Cornelius Gross, Interim Head of EMBL Rome, has joined the Earth, Brain and Health Commission. In partnership with Nature Mental Health, the commission aims to bring together an interdisciplinary group of world-class leaders to develop cutting edge and…
Genome-wide association studies (GWAS) focusing on common single nucleotide polymorphism (SNPs) have advanced our understanding of the genetic causes of many traits and diseases. However, for some conditions, this method is reaching its limits. To better understand the genetic basis of diseases,…
EMBL researchers and collaborators have shown gut bacteria can alter how some carcinogens are metabolised and distributed elsewhere, that leads to bladder cancer. The study can help better understand how individuals' gut microbiota affects tumour growth.
This workshop aimed to identify quantitative molecular proxies of environmental exposures through bringing together experts from across epidemiology, toxicology, social science, and computational biology.
A study from the Hackett group at EMBL Rome shows that disrupting the gut microbiome of male mice increases the risk of disease in their future offspring.