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EMBL Imaging Centre

Open access to cutting-edge electron and light microscopy

We provide researchers from Europe and beyond with a synergistic portfolio of imaging services including cryo-EM, super-resolution and intravital microscopy to enable new ground-breaking research that crosses the scales of biology.

High-End Data Collection

Titan Krios G4

The Titan Krios G4 from Thermo Fisher Scientific is a 300 kV transmission electron microscope (TEM) with a three-condenser lens system. It features the latest technology for high-end single-particle and tomography data acquisition including a cold field emission gun (C-FEG), SelectrisX energy filter, Falcon 4 electron counting camera and volta phase plate. It’s configured for high-throughput automated single particle and tomography data acquisition.


Features

  • C-FEG electron source with narrow energy spread
  • State-of-the-art energy filter and electron counting camera
  • phase plate
  • Autoloader system for easy sample transfer between TFS TEMs

Specifications

  • 300 kV C-FEG electron source
  • SelectrisX energy filter
  • Falcon 4EC direct electron detector
  • Volta phase plate
  • SerialEM software for tailored, automated data acquisition
Cryo-EM density map after 3D reconstruction with an atomic coordinate model fitted.
Credit: Stuart Ingham/EMBL.
Thermo Fisher Scientific Titan Krios. Credit: Stuart Ingham/EMBL.

Glacios

The Glacios from Thermo Fisher Scientific is a 200 kV transmission electron microscope with a two-condenser lens system. It’s equipped with an autoloader system which allows for quick screening of up to 12 cryo-EM samples. The system also features the latest state-of-the-art SelectrisX energy filter and Falcon 4 electron counting camera which enables high-quality data collection for suitable single particle samples.


Unique features

  • Autoloader system for easy sample transfer between TFS TEMs
  • State-of-the-art energy filter and electron counting camera

Important specifications

  • 200 kV FEG electron source
  • SelectrisX energy filter
  • Falcon 4EC direct electron detector
  • SerialEM software for tailored, automated data acquisition
Cryo-EM micrograph of an exemplary single-particle sample.
Credit: Stuart Ingham/EMBL
Thermo Fisher Scientific Glacios. Credit: Stuart Ingham/EMBL.
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