Kim Remans
Head of Protein Expression and Purification Core Facility
EditUnderstanding life in its natural context
Recombinant protein production for facilitating molecular investigations of non-classical organisms.
Purified proteins are useful biological tools that are used for many purposes, such as obtaining molecular-level insights into functional mechanisms, studying interactions and generating antibodies/nanobodies. In contrast to proteins from model organisms, robust methods for the production of proteins from non-classical organisms are lacking, thereby hindering proper molecular-level investigations.
By testing both established and less standardly used expression systems, we aim to figure out the relationships between the environmental origins of the non-classical organisms, the molecular and functional characteristics of the proteins of interest and the most optimal host expression organisms.
Arendt group, EMBL Heidelberg
Head of Protein Expression and Purification Core Facility
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