Analytical and organic chemistry services
If you require a specific molecule for your research that is not readily available from chemical suppliers, our facility offers synthesis services tailored to your needs. First, we will provide you with a comprehensive cost estimate for custom synthesis. Upon agreement, we initiate working on your request and ensure timely delivery of desired molecules.
Our expertise covers chemical probes designed for applications in imaging and target identification. In cases where you possess a bioactive compound but lack information about its biological target, our team can design chemical probes specifically crafted for target/off-target identification.
We offer comprehensive support for initial structure-activity relationship studies aimed at enhancing the potency of your hit compounds identified during primary screenings. We synthesize small compound libraries using state-of-the-art parallel reaction stations. Additionally, we can assist you in pursuing external funding opportunities to advance your research. In the event of successful collaboration, we can accommodate postdoctoral researchers who mainly work on your medicinal chemistry project under our supervision.
Our laboratory is equipped with a dedicated semi-preparative high-performance liquid chromatography (HPLC) instrument designed for the purification of fluorescently labeled oligonucleotides. We ensure the highest quality and purity of your oligonucleotide samples.
If you have concerns regarding the purity of chemicals you have bought, we offer quality control services for your samples, whether they are in vials or 96-well plates. Our analysis utilizes an ultra-performance liquid chromatography-mass spectrometry-evaporative light scattering detection (UPLC-MS-ELSD) instrument to provide an accurate measurement of purity.
When you require expert advice or a second opinion from a chemist, our team is readily available to assist you. We address your chemistry-related inquiries or guide you towards specialists in related fields.
When your project requires specialized services beyond our scope and capacity, we can help you connect with external companies that have the necessary expertise to fulfill your needs. Depending on your preferences, we can also manage outsourced projects on your behalf.
We offer access to visitor fume hoods and comprehensive training in our chemistry laboratory for researchers engaged in interdisciplinary projects at EMBL. Our team will provide the necessary guidance and supervision to ensure the successful execution of your research. Visitors will have full access to our laboratory infrastructure.
Upon request, we provide you a detailed cost estimate for your project. In addition to specific materials and consumables required for the synthesis, we charge a fixed service fee per synthetic step as a contribution to maintenance costs for the instruments used.