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Dorrity Group

Environmental response at the single-cell level

Publications

Total number of publications:

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2024

Bourn, J. J., Dorrity, M. W. (2024). Degrees of freedom: temperature’s influence on developmental rate. Current Opinion in Genetics & Development, 85, 102155

2023

Dorrity, M. W., Saunders, L. M., Duran, M., Srivatsan, S. R., Barkan, E., Jackson, D. L., … & Trapnell, C. (2023). Proteostasis governs differential temperature sensitivity across embryonic cell types. Cell, 186(23), 5015-5027.

Saunders, L. M., Srivatsan, S. R., Duran, M., Dorrity, M. W., Ewing, B., Linbo, T. H., … & Trapnell, C. (2023). Embryo-scale reverse genetics at single-cell resolution. Nature, 1-10.

2022

Kim, E.D.*, Dorrity, M.W.*, Fitzgerald, B.A., Seo, H., Sepuru, K.M., Queitsch, C., Mitsuda, N., Han, S.K. and Torii, K.U., 2022. Dynamic chromatin accessibility deploys heterotypic cis/trans-acting factors driving stomatal cell-fate commitment. Nature Plants, pp.1-14.

Dorrity, M.W., Saunders, L.M., Duran, M., Srivatsan, S.R., Ewing, B., Queitsch, C., Shendure, J., Raible, D., Kimelman, D. and Trapnell, C., 2022. Proteostasis governs differential temperature sensitivity across embryonic cell types. bioRxiv.

Saunders, L.M., Srivatsan, S.R., Duran, M., Dorrity, M.W., Ewing, B., Linbo, T., Shendure, J., Raible, D., Moens, C.B., Kimelman, D. and Trapnell, C., 2022. Deep molecular, cellular and temporal phenotyping of developmental perturbations at whole organism scale. bioRxiv.

2021

Dorrity, M. W., Alexandre, C., Hamm, M., Vigil, A., Fields, S., Queitsch, C., Cuperus, J., 2021. The regulatory landscape of Arabidopsis thaliana roots at single-cell resolution. Nature Communications doi: https://doi.org/10.1038/s41467-021-23675-y

2020

Morton, E. A.*, Dorrity, M. W.*, Zhou, W., Fields, S., Queitsch, C., 2020. Transcriptional re-wiring by mutation of the yeast Hsf1 oligomerization domain. bioRxiv doi: https://doi.org/10.1101/2020.05.23.112250

 Dorrity, M. W.*, Saunders, L. M.*, Queitsch, C., Fields, S., & Trapnell, C., 2020. Dimensionality reduction by UMAP to visualize physical and genetic interactions. Nature Communications 11: 1537

Jores, T., Tonnies, J., Dorrity, M. W., Cuperus, J. T., Fields, S., & Queitsch, C. 2020. Identification of plant enhancers and their constituent elements by STARR-seq in tobacco leaves. The Plant Cell. 32:2120-2131.

 Zhou, W., Dorrity, M.W., Bubb, K.L., Queitsch, C., Fields, S., 2020. Binding and regulation of transcription by yeast Ste12 variants to drive mating and invasion phenotypes. Genetics 214.2: 397-407.

2019

Dorrity, M.W., Queitsch, C. and Fields, S., 2019. High-throughput identification of dominant negative polypeptides in yeast. Nature Methods 16:413.

 Jean-Baptiste, K., McFaline-Figueroa, J.L., Alexandre, C.M., Dorrity, M.W., Saunders, L., Bubb, K.L., Trapnell, C., Fields, S., Queitsch, C., Cuperus, J.T., 2019. Dynamics of Gene Expression in Single Root Cells of Arabidopsis thaliana. The Plant Cell 31: 993-1011.

 

2018

Dorrity, M.W., Cuperus, J.T., Carlisle, J.A., Fields, S. and Queitsch, C., 2018. Preferences in a trait decision determined by transcription factor variants. Proceedings of the National Academy of Sciences115:E7997-E8006.

 Maher, K.A., Bajic, M., Kajala, K., Reynoso, M., Pauluzzi, G., West, D.A., Zumstein, K., Woodhouse, M., Bubb, K., Dorrity, M.W. and Queitsch, C., 2018. Profiling of accessible chromatin regions across multiple plant species and cell types reveals common gene regulatory principles and new control modules. The Plant Cell30:15-36.

 

2017

Alexandre, C.M., Urton, J.R., Jean-Baptiste, K., Huddleston, J., Dorrity, M.W., Cuperus, J.T., Sullivan, A.M., Bemm, F., Jolic, D., Arsovski, A.A. Thompson, A., and Queitsch, C. 2017. Complex relationships between chromatin accessibility, sequence divergence, and gene expression in Arabidopsis thaliana. Molecular Biology and Evolution35:837-854.

2013

Ron, M., Dorrity M.W., de Lucas, M., Toal ,T., Hernandez ,R.I., Little, S.A., Maloof, J.N., Kliebenstein, D.J., and Brady, S.M. 2013. Identification of novel loci regulating interspecific variation in root morphology and cellular development in tomato. Plant Physiology 162:755-768.

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