Casting new light on gene regulation in development
New research from EMBL Heidelberg shows how cells in developing embryos undergo a major shift in the way they regulate gene expression as they mature and differentiate.
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Zooming in to get the full picture
EMBL and UW researchers plus additional collaborators have constructed a complete map of fruit fly embryonic development using machine learning. This research is foundational to better understanding o…
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Royal Society honour for Eileen Furlong
EMBL’s Head of Genome Biology announced as Fellow of the Royal Society for her exceptional contributions to science.
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Converging lenses on embryo development
Researchers from the Furlong group at EMBL have come up with a way to observe the development of fruit-fly embryos simultaneously at the genetic and cellular levels, generating a high-resolution and i…
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Predicting how gene expression varies
Discoveries at EMBL will help researchers to interpret one of the most common types of experiments in genomics and medical studies.
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Rearranging chromosomes
Does rearranging chromosomes affect their function? EMBL scientists reveal uncoupling of 3D chromatin organisation and gene expression.
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Chromatin usage reveals developmental trajectories
EMBL scientists show how chromatin usage in individual cells reveals developmental trajectories
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Multipurpose enhancers and promoters in embryonic development
EMBL scientists show that some promoters can act as enhancers and vice versa
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Futures: Genome regulation
ERC grantee Eileen Furlong shares her vision for the next ten years
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Genetic switches can change shape
EMBL scientists discovered that common mutations can change the shape of gene promoters
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Buffering mechanism protects embryonic development
New mechanism revealed
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Surprisingly stable long-distance relationships
Surprising finding: enhancers find their targets long before activation in Drosophila embryos
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Collective action
If you wanted to draw your family tree, you could start by searching for people who share your surname. Cells, of course, don’t have surnames, but scientists at the European Molecular Biology Laborato…
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Tracking genes’ remote controls
As an embryo develops, different genes are turned on in different cells, to form muscles, neurons and other bodily parts. Inside each cell’s nucleus, genetic sequences known as enhancers act like remo…
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Deciphering the regulatory code
Embryonic development is like a well-organised building project, with the embryo’s DNA serving as the blueprint from which all construction details are derived. Cells carry out different functions acc…
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