Structure and function of RNA-protein complexes
Our latest collaboration with Sarah Offley and Alessandro Gardini group from the Wistar Institute provides new insights into the structure and function of the previously uncharacterized protein associated with the Integrator complex. We used functional genomics to show that INTS15 is a core…
Jonas Tholen is a graduate student winner of the 2023 Scaringe award from the RNA Society for his work on the U2 snRNP structure. Big congratulations !
Congratulations to our newest PhD, Jonas Tholen!!! Jonas determined structures of several U2 snRNP complexes and defended his thesis at the University of Heidelberg in November this year. Well done Jonas!
Great scientific exchanges and leisure activities during our joint retreat with Eustermann group from EMBL Heidelberg. We spent 3 days together at a beautiful venue of Château de Bournel (France).Looking forward to the next one!
Check out our latest review in Current Opinion in Structural Biology summarizing recent progress in mechanistic studies of the spliceosome.
The summer is here!
Our brief summary of the recent progress in understanding the structure and function of the Integrator complex was just published in Transcription. Moritz M. Pfleiderer & Wojciech P. Galej (2022) Emerging insights into the function and structure of the Integrator complex. Transcription,…
Every year we take a day off and go skiing together. This time we went to Alpe d’Huez. Beautiful mountains and fantastic weather, only 1.5h away from Grenoble!
https://www.science.org/doi/10.1126/science.abm4245
Our snowshoeing trip had to be cancelled due to bad weather conditions, but at least we made it to a fondue restaurant and enjoyed some nice winter food!