Structural biology of macromolecular protein-RNA complexes
Structural basis of Spliced Leader RNA recognition by the Trypanosoma brucei cap-binding complex. Bernhard H, Petrzilkova H, Popelarova B, Ziemkiewicz K, Bartosik K, Warminski M, Tengo L, Gröger H, Dolce LG, Micura R, Jemielity J, Kowalinski E bioRxiv, 2024 doi:10.1101/2024.05.04.591051.
Structure of the m3C-tRNA methyltransferase METTL6 bound to seryl-tRNA synthetase and substrate RNA Structural basis of tRNA recognition by the m3C-RNA-methyltransferase METTL6 in complex with SerRS seryl-tRNA synthetase. Throll P, Dolce LG, Lastres PR, Arnold K, Tengo L, Basu S, Kaiser S,…
ADAT2/3 structure bound to tRNA out in Nature Commincations. Structural basis for sequence-independent substrate selection by eukaryotic wobble base tRNA deaminase ADAT2/3. Dolce LG, Zimmer AA, Tengo L, Weis F, Rubio MAT, Alfonzo JD, Kowalinski E Nature communications, 2022…
Sequence-independent substrate selection by the eukaryotic wobble base deaminase ADAT2/3 involves multiple protein domains and distortion of the tRNA anticodon loop The essential deamination of adenosine A34 to inosine at the wobble base is the individual tRNA modification with the greatest effects…