Main Equipment in the AML

Confocal laser scanning microscope – LSM 900, Zeiss

Fluorescence signals from molecules to organisms can be observed in high resolution of ~200 nm in x/y and ~ 500 nm in z.

Large particle sorter – COPAS Vision 500, Union Biometrica

An innovative image-based sorter capable of isolating large organisms up to 400 µm in diameter and several mm in length.

High Pressure Freezer – Leica EM ICE, Leica Microsystems

High pressure freezing enables rapid vitrification (within 20 ms) of small biological samples (up to 200 µm in height and 6mm in diameter) for electron microscopy analyses.

Plunge Freezer – Vitrobot, Thermofisher Scientific

Plunge freezing allows the preservation of single cells for analysis with cryo EM.

Inverted fluorescence microscope – AxioVert, Zeiss

Inverted fluorescence microscope for sample inspection with colour camera.

Stereo microscope – Stemi 508, Zeiss

Binoculars for brightfield sample inspection with colour camera.

Fluorescence stereo zoom microscope – AxioZoom, Zeiss

Stereo Microscope with fluorescence, Apotome and monochromatic camera.

Cryo fluorescence microscope – Axio Imager 2, Zeiss

Cryo Widefield Microscope for inspection of cryo preserved specimen, equipped with Linkam stage.

PELCO BioWave, Ted Pella

Microwave for sample fixation.

Additional Equipment

The following equipment is (semi)permanently installed in the AML to support the sample preparation needed before/after the advanced technologies.