Comparative chromatin accessibility upon BDNF stimulation delineates neuronal regulatory elements.

Ibarra IL, Ratnu VS, Gordillo L, Hwang IY, Mariani L, Weinand K, Hammarén HM, Heck J, Bulyk ML, Savitski MM, Zaugg JB, Noh KM

Molecular systems biology, 2022

doi:10.15252/msb.202110473.

Multi-omic profiling of histone variant H3.3 lysine 27 methylation reveals a distinct role from canonical H3 in stem cell differentiation.

Kori Y, Lund PJ, Trovato M, Sidoli S, Yuan ZF, Noh KM, Garcia BA

Molecular omics, 2022

doi:10.1039/d1mo00352f.

High-throughput functional characterization of protein phosphorylation sites in yeast.

Viéitez C, Busby BP, Ochoa D, Mateus A, Memon D, Galardini M, Yildiz U, Trovato M, Jawed A, Geiger AG, Oborská-Oplová M, Potel CM, Vonesch SC, Szu Tu C, Shahraz M, Stein F, Steinmetz LM, Panse VG, Noh KM, Savitski MM, Typas A, Beltrao P

Nature biotechnology, 2021

doi:10.1038/s41587-021-01051-x.

Donor cell memory confers a metastable state of directly converted cells.

Kim KP, Li C, Bunina D, Jeong HW, Ghelman J, Yoon J, Shin B, Park H, Han DW, Zaugg JB, Kim J, Kuhlmann T, Adams RH, Noh KM, Goldman SA, Schöler HR

Cell stem cell, 2021

doi:10.1016/j.stem.2021.02.023.

Histone variant H3.3 mutations in defining the chromatin function in mammals.

Trovato M, Patil V, Gehre M, Noh KM

Cells, 2020

doi:10.3390/cells9122716.

Genomic rewiring of SOX2 chromatin interaction network during differentiation of ESCs to postmitotic neurons.

Bunina D, Abazova N, Diaz N, Noh KM, Krijgsveld J, Zaugg JB

Cell systems, 2020

doi:10.1016/j.cels.2020.05.003.

Lysine 4 of histone H3.3 is required for embryonic stem cell differentiation, histone enrichment at regulatory regions and transcription accuracy.

Gehre M, Bunina D, Sidoli S, Lübke MJ, Diaz N, Trovato M, Garcia BA, Zaugg JB, Noh KM

Nature genetics, 2020

doi:10.1038/s41588-020-0586-5.

The functional landscape of the human phosphoproteome.

Ochoa D, Jarnuczak AF, Viéitez C, Gehre M, Soucheray M, Mateus A, Kleefeldt AA, Hill A, Garcia-Alonso L, Stein F, Krogan NJ, Savitski MM, Swaney DL, Vizcaíno JA, Noh KM, Beltrao P

Nature biotechnology, 2019

doi:10.1038/s41587-019-0344-3.

Haploinsufficiency of the intellectual disability gene SETD5 disturbs developmental gene expression and cognition.

Deliu E, Arecco N, Morandell J, Dotter CP, Contreras X, Girardot C, Käsper EL, Kozlova A, Kishi K, Chiaradia I, Noh KM, Novarino G

Nature neuroscience, 2018

doi:10.1038/s41593-018-0266-2.

Systematic analysis of protein turnover in primary cells.

Mathieson T, Franken H, Kosinski J, Kurzawa N, Zinn N, Sweetman G, Poeckel D, Ratnu VS, Schramm M, Becher I, Steidel M, Noh KM, Bergamini G, Beck M, Bantscheff M, Savitski MM

Nature communications, 2018

doi:10.1038/s41467-018-03106-1.

CTCF-Mediated Chromatin Loops between Promoter and Gene Body Regulate Alternative Splicing across Individuals.

Ruiz-Velasco M, Kumar M, Lai MC, Bhat P, Solis-Pinson AB, Reyes A, Kleinsorg S, Noh KM, Gibson TJ, Zaugg JB

Cell systems, 2017

doi:10.1016/j.cels.2017.10.018.

Intragenic CpG islands play important roles in bivalent chromatin assembly of developmental genes.

Lee SM, Lee J, Noh KM, Choi WY, Jeon S, Oh GT, Kim-Ha J, Jin Y, Cho SW, Kim YJ

Proceedings of the National Academy of Sciences of the United States of America, 2017

doi:10.1073/pnas.1613300114.

Reading between the Lines: "ADD"-ing Histone and DNA Methylation Marks toward a New Epigenetic "Sum".

Noh KM, Allis CD, Li H

ACS chemical biology, 2015

doi:10.1021/acschembio.5b00830.

Critical Role of Histone Turnover in Neuronal Transcription and Plasticity.

Maze I, Wenderski W, Noh KM, Bagot RC, Tzavaras N, Purushothaman I, Elsässer SJ, Guo Y, Ionete C, Hurd YL, Tamminga CA, Halene T, Farrelly L, Soshnev AA, Wen D, Rafii S, Birtwistle MR, Akbarian S, Buchholz BA, Blitzer RD, Nestler EJ, Yuan ZF, Garcia BA, Shen L, Molina H, Allis CD

Neuron, 2015

doi:10.1016/j.neuron.2015.06.014.

Histone H3.3 is required for endogenous retroviral element silencing in embryonic stem cells.

Elsässer SJ, Noh KM, Diaz N, Allis CD, Banaszynski LA

Nature, 2015

doi:10.1038/nature14345.

Engineering of a Histone-Recognition Domain in Dnmt3a Alters the Epigenetic Landscape and Phenotypic Features of Mouse ESCs.

Noh KM, Wang H, Kim HR, Wenderski W, Fang F, Li CH, Dewell S, Hughes SH, Melnick AM, Patel DJ, Li H, Allis CD

Molecular cell, 2015

doi:10.1016/j.molcel.2015.05.017.

ATRX tolerates activity-dependent histone H3 methyl/phos switching to maintain repetitive element silencing in neurons.

Noh KM, Maze I, Zhao D, Xiang B, Wenderski W, Lewis PW, Shen L, Li H, Allis CD

Proceedings of the National Academy of Sciences of the United States of America, 2015

doi:10.1073/pnas.1411258112.

Genome editing a mouse locus encoding a variant histone, H3.3B, to report on its expression in live animals.

Wen D, Noh KM, Goldberg AD, Allis CD, Rosenwaks Z, Rafii S, Banaszynski LA

Genesis (New York, N.Y. : 2000), 2014

doi:10.1002/dvg.22827.

The gene silencing transcription factor REST represses miR-132 expression in hippocampal neurons destined to die.

Hwang JY, Kaneko N, Noh KM, Pontarelli F, Zukin RS

Journal of molecular biology, 2014

doi:10.1016/j.jmb.2014.07.032.

Histone variant H3.3 is an essential maternal factor for oocyte reprogramming.

Wen D, Banaszynski LA, Liu Y, Geng F, Noh KM, Xiang J, Elemento O, Rosenwaks Z, Allis CD, Rafii S

Proceedings of the National Academy of Sciences of the United States of America, 2014

doi:10.1073/pnas.1406389111.

Every amino acid matters: essential contributions of histone variants to mammalian development and disease

Maze I, Noh KM, Soshnev AA, Allis CD

Nature reviews. Genetics, 2014

doi:10.1038/nrg3673.

Histone regulation in the CNS: basic principles of epigenetic plasticity.

Maze I, Noh KM, Allis CD

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2012

doi:10.1038/npp.2012.124.

Repressor element-1 silencing transcription factor (REST)-dependent epigenetic remodeling is critical to ischemia-induced neuronal death

Noh KM, Hwang JY, Follenzi A, Athanasiadou R, Miyawaki T, Greally JM, Bennett MV, Zukin RS

Proceedings of the National Academy of Sciences of the United States of America, 2012

doi:10.1073/pnas.1121568109.

Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres.

Lewis PW, Elsaesser SJ, Noh KM, Stadler SC, Allis CD

Proceedings of the National Academy of Sciences of the United States of America, 2010

doi:10.1073/pnas.1008850107.

Distinct factors control histone variant H3.3 localization at specific genomic regions

Goldberg AD, Banaszynski LA, Noh KM, Lewis PW, Elsaesser SJ, Stadler S, Dewell S, Law M, Guo X, Li X, Wen D, Chapgier A, DeKelver RC, Miller JC, Lee YL, Boydston EA, Holmes MC, Gregory PD, Greally JM, Rafii S, Yang C, Scambler PJ, Garrick D, Gibbons RJ, Higgs DR, Cristea IM, Urnov FD, Zheng D, Allis CD

Cell, 2010

doi:10.1016/j.cell.2010.01.003.

The endogenous inhibitor of Akt, CTMP, is critical to ischemia-induced neuronal death.

Miyawaki T, Ofengeim D, Noh KM, Latuszek-Barrantes A, Hemmings BA, Follenzi A, Zukin RS

Nature neuroscience, 2009

doi:10.1038/nn.2299.

Ischemic preconditioning blocks BAD translocation, Bcl-xL cleavage, and large channel activity in mitochondria of postischemic hippocampal neurons.

Miyawaki T, Mashiko T, Ofengeim D, Flannery RJ, Noh KM, Fujisawa S, Bonanni L, Bennett MV, Zukin RS, Jonas EA

Proceedings of the National Academy of Sciences of the United States of America, 2008

doi:10.1073/pnas.0800628105.

Ischemic insults promote epigenetic reprogramming of mu opioid receptor expression in hippocampal neurons.

Formisano L, Noh KM, Miyawaki T, Mashiko T, Bennett MV, Zukin RS

Proceedings of the National Academy of Sciences of the United States of America, 2007

doi:10.1073/pnas.0611704104.

Activity bidirectionally regulates AMPA receptor mRNA abundance in dendrites of hippocampal neurons

Grooms SY, Noh KM, Regis R, Bassell GJ, Bryan MK, Carroll RC, Zukin RS

The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006

doi:10.1523/jneurosci.0472-06.2006.

Blockade of calcium-permeable AMPA receptors protects hippocampal neurons against global ischemia-induced death

Noh KM, Yokota H, Mashiko T, Castillo PE, Zukin RS, Bennett MV

Proceedings of the National Academy of Sciences of the United States of America, 2005

doi:10.1073/pnas.0505408102.

Late calcium EDTA rescues hippocampal CA1 neurons from global ischemia-induced death.

Calderone A, Jover T, Mashiko T, Noh KM, Tanaka H, Bennett MV, Zukin RS

The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004

doi:10.1523/jneurosci.1713-04.2004.

Ischemic insults derepress the gene silencer REST in neurons destined to die.

Calderone A, Jover T, Noh KM, Tanaka H, Yokota H, Lin Y, Grooms SY, Regis R, Bennett MV, Zukin RS

The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003

doi:.

Iron promotes the survival and neurite extension of serum-starved PC12 cells in the presence of NGF by enhancing cell attachment.

Hong JH, Noh KM, Yoo YE, Choi SY, Park SY, Kim YH, Chung JM

Molecules and cells, 2003

doi:.

Induction and activation by zinc of NADPH oxidase in cultured cortical neurons and astrocytes.

Noh KM, Koh JY

The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000

doi:.

A novel neuroprotective mechanism of riluzole: direct inhibition of protein kinase C.

Noh KM, Hwang JY, Shin HC, Koh JY

Neurobiology of disease, 2000

doi:10.1006/nbdi.2000.0297.

Insulin-induced oxidative neuronal injury in cortical culture: mediation by induced N-methyl-D-aspartate receptors.

Noh KM, Lee JC, Ahn YH, Hong SH, Koh JY

IUBMB life, 1999

doi:10.1080/713803514.

Mediation by membrane protein kinase C of zinc-induced oxidative neuronal injury in mouse cortical cultures.

Noh KM, Kim YH, Koh JY

Journal of neurochemistry, 1999

doi:10.1046/j.1471-4159.1999.721609.x.

Cryo-ET suggests tubulin chaperones form a subset of microtubule lumenal particles with a role in maintaining neuronal microtubules.

Chakraborty S, Martinez-Sanchez A, Beck F, Toro-Nahuelpan M, Hwang IY, Noh KM, Baumeister W, Mahamid J

Proceedings of the National Academy of Sciences of the United States of America, 2025

doi:10.1073/pnas.2404017121.

HIPSD&R-seq enables scalable genomic copy number and transcriptome profiling.

Otoničar J, Lazareva O, Mallm JP, Simovic-Lorenz M, Philippos G, Sant P, Parekh U, Hammann L, Li A, Yildiz U, Marttinen M, Zaugg J, Noh KM, Stegle O, Ernst A

Genome biology, 2024

doi:10.1186/s13059-024-03450-0.

Histone H3.3 lysine 9 and 27 control repressive chromatin at cryptic enhancers and bivalent promoters.

Trovato M, Bunina D, Yildiz U, Fernandez-Novel Marx N, Uckelmann M, Levina V, Perez Y, Janeva A, Garcia BA, Davidovich C, Zaugg JB, Noh KM

Nature communications, 2024

doi:10.1038/s41467-024-51785-w.

Lipotype acquisition during neural development is not recapitulated in stem cell-derived neurons.

Gopalan AB, van Uden L, Sprenger RR, Fernandez-Novel Marx N, Bogetofte H, Neveu PA, Meyer M, Noh KM, Diz-Muñoz A, Ejsing CS

Life science alliance, 2024

doi:10.26508/lsa.202402622.

Scalable ultra-high-throughput single-cell chromatin and RNA sequencing reveals gene regulatory dynamics linking macrophage polarization to autoimmune disease.

Lobato-Moreno S, Yildiz U, Claringbould A, Servaas NH, Vlachou EP, Arnold C, Bauersachs HG, Campos-Fornés V, Prummel KD, Noh KM, Marttinen M, Zaugg JB

bioRxiv, 2024

doi:10.1101/2023.12.26.573253.

Direct observation of motor protein stepping in living cells using MINFLUX.

Deguchi T, Iwanski MK, Schentarra EM, Heidebrecht C, Schmidt L, Heck J, Weihs T, Schnorrenberg S, Hoess P, Liu S, Chevyreva V, Noh KM, Kapitein LC, Ries J

Science (New York, N.Y.), 2023

doi:10.1126/science.ade2676.