Early autonomous patterning of the anteroposterior axis in gastruloids.

Anlaş K, Gritti N, Nakaki F, Salamó Palau L, Tlili SL, Oriola D, Arató K, Le Lim J, Sharpe J, Trivedi V

Development (Cambridge, England), 2024

doi:10.1242/dev.202171.

Versatile system cores as a conceptual basis for generality in cell and developmental biology.

Gallo E, De Renzis S, Sharpe J, Mayor R, Hartmann J

Cell systems, 2024

doi:10.1016/j.cels.2024.08.001.

Exocrine gland-resident memory CD8+ T cells use mechanosensing for tissue surveillance.

Ruef N, Martínez Magdaleno J, Ficht X, Purvanov V, Palayret M, Wissmann S, Pfenninger P, Stolp B, Thelen F, Barreto de Albuquerque J, Germann P, Sharpe J, Abe J, Legler DF, Stein JV

Science immunology, 2023

doi:10.1126/sciimmunol.add5724.

Multimodal in vivo imaging of the integrated postnatal development of brain and skull and Its co-modulation with neurodevelopment in a Down Syndrome Mouse model.

Llambrich S, González R, Albaigès J, Wouters J, Marain F, Himmelreich U, Sharpe J, Dierssen M, Gsell W, Martínez-Abadías N, Vande Velde G

Frontiers in medicine, 2022

doi:10.3389/fmed.2022.815739.

Green tea catechins modulate skeletal development with effects dependent on dose, time, and structure in a Down syndrome mouse model.

Llambrich S, González-Colom R, Wouters J, Roldán J, Salassa S, Wouters K, Van Bulck V, Sharpe J, Callaerts-Vegh Z, Vande Velde G, Martínez-Abadías N

Nutrients, 2022

doi:10.3390/nu14194167.

4D reconstruction of murine developmental trajectories using spherical harmonics.

Dalmasso G, Musy M, Niksic M, Robert-Moreno A, Badía-Careaga C, Sanz-Ezquerro JJ, Sharpe J

Developmental cell, 2022

doi:10.1016/j.devcel.2022.08.005.

Arrested coalescence of multicellular aggregates.

Oriola D, Marin-Riera M, Anlaş K, Gritti N, Sanaki-Matsumiya M, Aalderink G, Ebisuya M, Sharpe J, Trivedi V

Soft matter, 2022

doi:10.1039/d2sm00063f.

Dose dependent effects of green tea extracts in the skeletal development of a Down syndrome mouse model.

Martínez Abadías N, Llambrich S, González R, Albaigès JM, Wouters J, Roldán J, Salassa S, Van Bulck V, Wouters K, Callaerts-Vegh Z, Sharpe J, Dierssen M, Vande Velde G

FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2022

doi:10.1096/fasebj.2022.36.s1.r4982.

Periodic formation of epithelial somites from human pluripotent stem cells.

Sanaki-Matsumiya M, Matsuda M, Gritti N, Nakaki F, Sharpe J, Trivedi V, Ebisuya M

Nature communications, 2022

doi:10.1038/s41467-022-29967-1.

Green tea extracts containing epigallocatechin-3-gallate modulate facial development in Down syndrome.

Starbuck JM, Llambrich S, Gonzàlez R, Albaigès J, Sarlé A, Wouters J, González A, Sevillano X, Sharpe J, De La Torre R, Dierssen M, Vande Velde G, Martínez-Abadías N

Scientific reports, 2021

doi:10.1038/s41598-021-83757-1.

Dynamics of anteroposterior axis establishment in a mammalian embryo-like system.

Anlas K, Gritti N, Oriola D, Arató K, Nakaki F, Lim JL, Sharpe J, Trivedi V

2021

doi:10.1101/2021.02.24.432766.

ViceCT and whiceCT for simultaneous high-resolution visualization of craniofacial, brain and ventricular anatomy from micro-computed tomography.

Llambrich S, Wouters J, Himmelreich U, Dierssen M, Sharpe J, Gsell W, Martínez-Abadías N, Vande Velde G

Scientific reports, 2020

doi:10.1038/s41598-020-75720-3.

Topologically selective islet vulnerability and self-sustained downregulation of markers for β-cell maturity in streptozotocin-induced diabetes.

Hahn M, van Krieken PP, Nord C, Alanentalo T, Morini F, Xiong Y, Eriksson M, Mayer J, Kostromina E, Ruas JL, Sharpe J, Pereira T, Berggren PO, Ilegems E, Ahlgren U

Communications biology, 2020

doi:10.1038/s42003-020-01243-2.

Endogenous CRISPR/Cas9 arrays for scalable whole-organism lineage tracing.

Cotterell J, Vila-Cejudo M, Batlle-Morera L, Sharpe J

Development (Cambridge, England), 2020

doi:10.1242/dev.184481.

Salivary gland macrophages and tissue-resident CD8+ T cells cooperate for homeostatic organ surveillance.

Stolp B, Thelen F, Ficht X, Altenburger LM, Ruef N, Inavalli VVGK, Germann P, Page N, Moalli F, Raimondi A, Keyser KA, Jafari SMS, Barone F, Dettmer MS, Merkler D, Sharpe J, Iannacone M, Fackler OT, Schlapbach C, Stein JV, Nägerl UV

Science immunology, 2020

doi:10.1126/sciimmunol.aaz4371.

Wolpert's French Flag: what's the problem?

Sharpe J

Development (Cambridge, England), 2019

doi:10.1242/dev.185967.

Toward controllable morphogenesis in large robot swarms.

Carrillo-Zapata D, Sharpe J, Winfield AFT, Giuggioli L, Hauert S

IEEE Robotics and Automation Letters, 2019

doi:10.1109/LRA.2019.2926961.

ya||a: GPU-powered spheroid models for mesenchyme and epithelium.

Germann P, Marin-Riera M, Sharpe J

Cell systems, 2019

doi:10.1016/j.cels.2019.02.007.

Perspective: The promise of multi-cellular engineered living systems

Kamm RD, Bashir R, Arora N, Dar RD, Gillette MU, Griffith LG, Kemp ML, Kinlaw K, Levin M, Martin AC, McDevitt TC, Nerem RM, Powers MJ, Saif TA, Sharpe J, Takayama S, Takeuchi S, Weiss R, Ye KM, Yevick HG, Zaman MH, Zaman MH

APL BIOENGINEERING, 2018

doi:10.1063/1.5038337.

Attenuation artifacts in light sheet fluorescence microscopy corrected by OPTiSPIM.

Mayer J, Robert-Moreno A, Sharpe J, Swoger J

Light, science & applications, 2018

doi:10.1038/s41377-018-0068-z.

Quantification of gene expression patterns to reveal the origins of abnormal morphogenesis.

Martínez-Abadías N, Mateu Estivill R, Sastre Tomas J, Motch Perrine S, Yoon M, Robert-Moreno A, Swoger J, Russo L, Kawasaki K, Richtsmeier J, Sharpe J

eLife, 2018

doi:10.7554/eLife.36405.

Synthetic circuits reveal how mechanisms of gene regulatory networks constrain evolution.

Schaerli Y, Jiménez A, Duarte JM, Mihajlovic L, Renggli J, Isalan M, Sharpe J, Wagner A

Molecular systems biology, 2018

doi:10.15252/msb.20178102.

The Rho regulator Myosin IXb enables nonlymphoid tissue seeding of protective CD8+ T cells.

Moalli F, Ficht X, Germann P, Vladymyrov M, Stolp B, de Vries I, Lyck R, Balmer J, Fiocchi A, Kreutzfeldt M, Merkler D, Iannacone M, Ariga A, Stoffel MH, Sharpe J, Bähler M, Sixt M, Diz-Muñoz A, Stein JV

The Journal of experimental medicine, 2018

doi:10.1084/jem.20170896.

Key Features of Turing Systems are Determined Purely by Network Topology

Diego X, Marcon L, Muller P, Sharpe J

PHYSICAL REVIEW X, 2018

doi:10.1103/PhysRevX.8.021071.

Non-linear scaling of CD8(+) T cell responses by bystander DCs

Abe J, Germann P, Ripoll J, Sharpe J, Stein JV

CYTOKINE, 2017

doi:.

Computer modeling in developmental biology: growing today, essential tomorrow.

Sharpe J

Development (Cambridge, England), 2017

doi:10.1242/dev.151274.

Migratory appendicular muscles precursor cells in the common ancestor to all vertebrates.

Okamoto E, Kusakabe R, Kuraku S, Hyodo S, Robert-Moreno A, Onimaru K, Sharpe J, Kuratani S, Tanaka M

Nature ecology & evolution, 2017

doi:10.1038/s41559-017-0330-4.

Antigen Availability and DOCK2-Driven Motility Govern CD4(+) T Cell Interactions with Dendritic Cells In Vivo.

Ackerknecht M, Gollmer K, Germann P, Ficht X, Abe J, Fukui Y, Swoger J, Ripoll J, Sharpe J, Stein JV

Journal of immunology (Baltimore, Md. : 1950), 2017

doi:10.4049/jimmunol.1601148.

A spectrum of modularity in multi-functional gene circuits.

Jiménez A, Cotterell J, Munteanu A, Sharpe J

Molecular systems biology, 2017

doi:10.15252/msb.20167347.

pMHC affinity controls duration of CD8+ T cell-DC interactions and imprints timing of effector differentiation versus expansion.

Ozga AJ, Moalli F, Abe J, Swoger J, Sharpe J, Zehn D, Kreutzfeldt M, Merkler D, Ripoll J, Stein JV

The Journal of experimental medicine, 2016

doi:10.1084/jem.20160206.

The fin-to-limb transition as the re-organization of a Turing pattern.

Onimaru K, Marcon L, Musy M, Tanaka M, Sharpe J

Nature communications, 2016

doi:10.1038/ncomms11582.

High-throughput mathematical analysis identifies Turing networks for patterning with equally diffusing signals.

Marcon L, Diego X, Sharpe J, Müller P

eLife, 2016

doi:10.7554/eLife.14022.

Light sheet fluorescence microscopy for in situ cell interaction analysis in mouse lymph nodes.

Abe J, Ozga AJ, Swoger J, Sharpe J, Ripoll J, Stein JV

Journal of immunological methods, 2016

doi:10.1016/j.jim.2016.01.015.

Geometric Morphometrics on Gene Expression Patterns Within Phenotypes: A Case Example on Limb Development.

Martínez-Abadías N, Mateu R, Niksic M, Russo L, Sharpe J

Systematic biology, 2016

doi:10.1093/sysbio/syv067.

A Local, Self-Organizing Reaction-Diffusion Model Can Explain Somite Patterning in Embryos.

Cotterell J, Robert-Moreno A, Sharpe J

Cell systems, 2015

doi:10.1016/j.cels.2015.10.002.

A shift in anterior-posterior positional information underlies the fin-to-limb evolution.

Onimaru K, Kuraku S, Takagi W, Hyodo S, Sharpe J, Tanaka M

eLife, 2015

doi:10.7554/eLife.07048.

Data-driven modelling of a gene regulatory network for cell fate decisions in the growing limb bud.

Uzkudun M, Marcon L, Sharpe J

Molecular systems biology, 2015

doi:10.15252/msb.20145882.

Dynamical feature extraction at the sensory periphery guides chemotaxis.

Schulze A, Gomez-Marin A, Rajendran VG, Lott G, Musy M, Ahammad P, Deogade A, Sharpe J, Riedl J, Jarriault D, Trautman ET, Werner C, Venkadesan M, Druckmann S, Jayaraman V, Louis M

eLife, 2015

doi:10.7554/eLife.06694.

Decrease in Cell Volume Generates Contractile Forces Driving Dorsal Closure.

Saias L, Swoger J, D'Angelo A, Hayes P, Colombelli J, Sharpe J, Salbreux G, Solon J

Developmental cell, 2015

doi:10.1016/j.devcel.2015.03.016.

Positional information and reaction-diffusion: two big ideas in developmental biology combine.

Green JB, Sharpe J

Development (Cambridge, England), 2015

doi:10.1242/dev.114991.

Dynamics of gene circuits shapes evolvability.

Jiménez A, Cotterell J, Munteanu A, Sharpe J

Proceedings of the National Academy of Sciences of the United States of America, 2015

doi:10.1073/pnas.1411065112.

Personalized respiratory medicine: exploring the horizon, addressing the issues. Summary of a BRN-AJRCCM workshop held in Barcelona on June 12, 2014.

Agustí A, Antó JM, Auffray C, Barbé F, Barreiro E, Dorca J, Escarrabill J, Faner R, Furlong LI, Garcia-Aymerich J, Gea J, Lindmark B, Monsó E, Plaza V, Puhan MA, Roca J, Ruiz-Manzano J, Sampietro-Colom L, Sanz F, Serrano L, Sharpe J, Sibila O, Silverman EK, Sterk PJ, Sznajder JI

American journal of respiratory and critical care medicine, 2015

doi:10.1164/rccm.201410-1935PP.

Developmental biology: Cells unite by trapping a signal.

Sharpe J

Nature, 2014

doi:10.1038/nature13933.

ESCRT-II/Vps25 constrains digit number by endosome-mediated selective modulation of FGF-SHH signaling.

Handschuh K, Feenstra J, Koss M, Ferretti E, Risolino M, Zewdu R, Sahai MA, Bénazet JD, Peng XP, Depew MJ, Quintana L, Sharpe J, Wang B, Alcorn H, Rivi R, Butcher S, Manak JR, Vaccari T, Weinstein H, Anderson KV, Lacy E, Selleri L

Cell reports, 2014

doi:10.1016/j.celrep.2014.09.019.

A unified design space of synthetic stripe-forming networks.

Schaerli Y, Munteanu A, Gili M, Cotterell J, Sharpe J, Isalan M

Nature communications, 2014

doi:10.1038/ncomms5905.

On the concept of mechanism in development

Jaeger J, Sharpe J

2014

doi:10.1093/acprof:oso/9780199671427.003.0004.

Modeling digits. Digit patterning is controlled by a Bmp-Sox9-Wnt Turing network modulated by morphogen gradients.

Raspopovic J, Marcon L, Russo L, Sharpe J

Science (New York, N.Y.), 2014

doi:10.1126/science.1252960.

Immobilized chicks as a model system for early-onset developmental dysplasia of the hip.

Nowlan NC, Chandaria V, Sharpe J

Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2014

doi:10.1002/jor.22606.

Design principles of stripe-forming motifs: the role of positive feedback.

Munteanu A, Cotterell J, Solé RV, Sharpe J

Scientific reports, 2014

doi:10.1038/srep05003.

Joint shape morphogenesis precedes cavitation of the developing hip joint.

Nowlan NC, Sharpe J

Journal of anatomy, 2014

doi:10.1111/joa.12143.

OPTiSPIM: integrating optical projection tomography in light sheet microscopy extends specimen characterization to nonfluorescent contrasts.

Mayer J, Robert-Moreno A, Danuser R, Stein JV, Sharpe J, Swoger J

Optics letters, 2014

doi:10.1364/OL.39.001053.

On the mechanical interplay between intra- and inter-synchronization during collective cell migration: a numerical investigation.

Allena R, Aubry D, Sharpe J

Bulletin of mathematical biology, 2013

doi:10.1007/s11538-013-9908-4.

A GDF5 point mutation strikes twice--causing BDA1 and SYNS2.

Degenkolbe E, König J, Zimmer J, Walther M, Reißner C, Nickel J, Plöger F, Raspopovic J, Sharpe J, Dathe K, Hecht JT, Mundlos S, Doelken SC, Seemann P

PLoS genetics, 2013

doi:10.1371/journal.pgen.1003846.

Senescence is a developmental mechanism that contributes to embryonic growth and patterning.

Storer M, Mas A, Robert-Moreno A, Pecoraro M, Ortells MC, Di Giacomo V, Yosef R, Pilpel N, Krizhanovsky V, Sharpe J, Keyes WM

Cell, 2013

doi:10.1016/j.cell.2013.10.041.

Intravital imaging of hair-cell development and regeneration in the zebrafish.

Pinto-Teixeira F, Muzzopappa M, Swoger J, Mineo A, Sharpe J, López-Schier H

Frontiers in neuroanatomy, 2013

doi:10.3389/fnana.2013.00033.

Naive B-cell trafficking is shaped by local chemokine availability and LFA-1-independent stromal interactions.

Coelho FM, Natale D, Soriano SF, Hons M, Swoger J, Mayer J, Danuser R, Scandella E, Pieczyk M, Zerwes HG, Junt T, Sailer AW, Ludewig B, Sharpe J, Figge MT, Stein JV

Blood, 2013

doi:10.1182/blood-2012-10-465336.

Mechanistic explanations for restricted evolutionary paths that emerge from gene regulatory networks.

Cotterell J, Sharpe J

PloS one, 2013

doi:10.1371/journal.pone.0061178.

Transfecting RNA quadruplexes results in few transcriptome perturbations.

Sanders PG, Cotterell J, Sharpe J, Isalan M

RNA biology, 2013

doi:10.4161/rna.22781.

Near Infrared Optical Projection Tomography for Assessments of beta-cell Mass Distribution in Diabetes Research

Eriksson AU, Svensson C, Hornblad A, Cheddad A, Kostromina E, Eriksson M, Norlin N, Pileggi A, Sharpe J, Georgsson F, Alanentalo T, Ahlgren U

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 2013

doi:10.3791/50238.

Near infrared optical projection tomography for assessments of β-cell mass distribution in diabetes research.

Eriksson AU, Svensson C, Hörnblad A, Cheddad A, Kostromina E, Eriksson M, Norlin N, Pileggi A, Sharpe J, Georgsson F, Alanentalo T, Ahlgren U

Journal of visualized experiments : JoVE, 2013

doi:10.3791/50238.

Turing patterns in development: what about the horse part?

Marcon L, Sharpe J

Current opinion in genetics & development, 2012

doi:10.1016/j.gde.2012.11.013.

Hox genes regulate digit patterning by controlling the wavelength of a Turing-type mechanism.

Sheth R, Marcon L, Bastida MF, Junco M, Quintana L, Dahn R, Kmita M, Sharpe J, Ros MA

Science (New York, N.Y.), 2012

doi:10.1126/science.1226804.

Quantitative measurements in 3-dimensional datasets of mouse lymph nodes resolve organ-wide functional dependencies.

Mayer J, Swoger J, Ozga AJ, Stein JV, Sharpe J

Computational and mathematical methods in medicine, 2012

doi:10.1155/2012/128431.

Image formation by linear and nonlinear digital scanned light-sheet fluorescence microscopy with Gaussian and Bessel beam profiles.

Olarte OE, Licea-Rodriguez J, Palero JA, Gualda EJ, Artigas D, Mayer J, Swoger J, Sharpe J, Rocha-Mendoza I, Rangel-Rojo R, Loza-Alvarez P

Biomedical optics express, 2012

doi:10.1364/BOE.3.001492.

Image processing assisted algorithms for optical projection tomography.

Cheddad A, Svensson C, Sharpe J, Georgsson F, Ahlgren U

IEEE transactions on medical imaging, 2012

doi:10.1109/TMI.2011.2161590.

Two ways to use imaging: focusing directly on mechanism, or indirectly via behaviour?

Sharpe J

Current opinion in genetics & development, 2011

doi:10.1016/j.gde.2011.08.012.

Optical projection tomography of vertebrate embryo development.

Quintana L, Sharpe J

Cold Spring Harbor protocols, 2011

doi:10.1101/pdb.top116.

Control of pelvic girdle development by genes of the Pbx family and Emx2.

Capellini TD, Handschuh K, Quintana L, Ferretti E, Di Giacomo G, Fantini S, Vaccari G, Clarke SL, Wenger AM, Bejerano G, Sharpe J, Zappavigna V, Selleri L

Developmental dynamics : an official publication of the American Association of Anatomists, 2011

doi:10.1002/dvdy.22617.

Budding Behaviors: Growth of the Limb as a Model of Morphogenesis

Hopyan S, Sharpe J, Yang YZ

DEVELOPMENTAL DYNAMICS, 2011

doi:10.1002/dvdy.22601.

A landmark-free morphometric staging system for the mouse limb bud.

Boehm B, Rautschka M, Quintana L, Raspopovic J, Jan Z, Sharpe J

DEVELOPMENT, 2011

doi:10.1242/dev.057547.

A computational clonal analysis of the developing mouse limb bud.

Marcon L, Arqués CG, Torres MS, Sharpe J

PLOS COMPUTATIONAL BIOLOGY, 2011

doi:10.1371/journal.pcbi.1001071.

Imaging in Developmental Biology

Sharpe J, Wong R, Yuste R

2011

doi:.

4D retrospective lineage tracing using SPIM for zebrafish organogenesis studies

Swoger J, Muzzopappa M, Lopez-Schier H, Sharpe J

JOURNAL OF BIOPHOTONICS, 2011

doi:10.1002/jbio.201000087.

An atlas of gene regulatory networks reveals multiple three-gene mechanisms for interpreting morphogen gradients

Cotterell J, Sharpe J

MOLECULAR SYSTEMS BIOLOGY, 2010

doi:10.1038/msb.2010.74.

Mechanobiology of embryonic skeletal development: Insights from animal models.

Nowlan NC, Sharpe J, Roddy KA, Prendergast PJ, Murphy P

BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS, 2010

doi:10.1002/bdrc.20184.

Scapula development is governed by genetic interactions of Pbx1 with its family members and with Emx2 via their cooperative control of Alx1

Capellini TD, Vaccari G, Ferretti E, Fantini S, He M, Pellegrini M, Quintana L, Di Giacomo G, Sharpe J, Selleri L, Zappavigna V

DEVELOPMENT, 2010

doi:10.1242/dev.048819.

The role of spatially controlled cell proliferation in limb bud morphogenesis.

Boehm B, Westerberg H, Lesnicar-Pucko G, Raja S, Rautschka M, Cotterell J, Swoger J, Sharpe J

PLOS BIOLOGY, 2010

doi:10.1371/journal.pbio.1000420.

Quantification and Three-Dimensional Imaging of the Insulitis-Induced Destruction of beta-Cells in Murine Type 1 Diabetes

Alanentalo T, Hornblad A, Mayans S, Nilsson AK, Sharpe J, Larefalk A, Ahlgren U, Holmberg D

DIABETES, 2010

doi:10.2337/db09-1400.

Clonal Analysis in Mice Underlines the Importance of Rhombomeric Boundaries in Cell Movement Restriction during Hindbrain Segmentation

Jimenez-Guri E, Udina F, Colas JF, Sharpe J, Padrón-Barthe L, Torres M, Pujades C

PLOS ONE, 2010

doi:10.1371/journal.pone.0010112.

Live optical projection tomography.

Colas JF, Sharpe J

Organogenesis, 2009

doi:10.4161/org.5.4.10426.

Genetic background influences embryonic lethality and the occurrence of neural tube defects in Men1 null mice: relevance to genetic modifiers

Lemos MC, Harding B, Reed AAC, Jeyabalan J, Walls GV, Bowl MR, Sharpe J, Wedden S, Moss JE, Ross A, Davidson D, Thakker RV

JOURNAL OF ENDOCRINOLOGY, 2009

doi:10.1677/JOE-09-0124.

Gene expression analysis of canonical Wnt pathway transcriptional regulators during early morphogenesis of the facial region in the mouse embryo

Vendrell V, Summerhurst K, Sharpe J, Davidson D, Murphy P

GENE EXPRESSION PATTERNS, 2009

doi:10.1016/j.gep.2009.03.001.

Evidence That Fgf10 Contributes to the Skeletal and Visceral Defects of an Apert Syndrome Mouse Model

Hajihosseini MK, Duarte R, Pegrum J, Donjacour A, Lana-Elola E, Rice DP, Sharpe J, Dickson C

DEVELOPMENTAL DYNAMICS, 2009

doi:10.1002/dvdy.21648.

High-resolution three-dimensional imaging of islet-infiltrate interactions based on optical projection tomography assessments of the intact adult mouse pancreas

Alanentalo T, Loren CE, Larefalk A, Sharpe J, Holmberg D, Ahlgren U

JOURNAL OF BIOMEDICAL OPTICS, 2008

doi:10.1117/1.3000430.

Fluorescence lifetime optical projection tomography

McGinty J, Tahir KR, Laine R, Talbot CB, Dunsby C, Neil MAA, Quintana L, Swoger J, Sharpe J, French PMW

JOURNAL OF BIOPHOTONICS, 2008

doi:10.1002/jbio.200810044.

In vitro whole-organ imaging: 4D quantification of growing mouse limb buds

Boot MJ, Westerberg CH, Sanz-Ezquerro J, Cotterell J, Schweitzer R, Torres M, Sharpe J

NATURE METHODS, 2008

doi:10.1038/nmeth.1219.

3D representation of Wnt and Frizzled gene expression patterns in the mouse embryo at embryonic day 11.5 (Ts19)

Summerhurst K, Stark M, Sharpe J, Davidson D, Murphy P

GENE EXPRESSION PATTERNS, 2008

doi:10.1016/j.gep.2008.01.007.

Localization and fate of Fgf10-expressing cells in the adult mouse brain implicate Fgf10 in control of neurogenesis

Hajihosseini MK, De Langhe S, Lana-Elola E, Morrison H, Sparshott N, Kelly R, Sharpe J, Rice D, Bellusci S

MOLECULAR AND CELLULAR NEUROSCIENCE, 2008

doi:10.1016/j.mcn.2008.01.008.

Cell tracing reveals a dorsoventral lineage restriction plane in the mouse limb bud mesenchyme

Arques CG, Doohan R, Sharpe J, Torres M

DEVELOPMENT, 2007

doi:10.1242/dev.02873.

Three-Dimensional Imaging of Drosophila melanogaster

McGurk L, Morrison H, Keegan LP, Sharpe J, O'Connell MA

PLOS ONE, 2007

doi:10.1371/journal.pone.0000834.

FishNet: an online database of zebrafish anatomy

Bryson-Richardson RJ, Berger S, Schilling TF, Hall TE, Cole NJ, Gibson AJ, Sharpe J, Currie PD

BMC BIOLOGY, 2007

doi:10.1186/1741-7007-5-34.

Resolution improvement in emission optical projection tomography

Walls JR, Sled JG, Sharpe J, Henkelman RM

PHYSICS IN MEDICINE AND BIOLOGY, 2007

doi:10.1088/0031-9155/52/10/010.

Tomographic molecular imaging and 3D quantification within adult mouse organs

Alanentalo T, Asayesh A, Morrison H, Loren CE, Holmberg D, Sharpe J, Ahlgren U

NATURE METHODS, 2006

doi:10.1038/NMETH985.

Visualizing plant development and gene expression in three dimensions using optical projection tomography.

Lee K, Avondo J, Morrison H, Blot L, Stark M, Sharpe J, Bangham A, Coen E

PLANT CELL, 2006

doi:10.1105/tpc.106.043042.

Spleen versus pancreas: strict control of organ interrelationship revealed by analyses of Bapx1-/- mice.

Asayesh A, Sharpe J, Watson RP, Hecksher-Sørensen J, Hastie ND, Hill RE, Ahlgren U

Genes & development, 2006

doi:10.1101/gad.381906.

Correction of artefacts in optical projection tomography

Walls JR, Sled JG, Sharpe J, Henkelman RM

PHYSICS IN MEDICINE AND BIOLOGY, 2005

doi:10.1088/0031-9155/50/19/015.

3D modelling, gene expression mapping and post-mapping image analysis in the developing human brain.

Sarma S, Kerwin J, Puelles L, Scott M, Strachan T, Feng G, Sharpe J, Davidson D, Baldock R, Lindsay S

Brain research bulletin, 2005

doi:10.1016/j.brainresbull.2005.05.022.

3 dimensional modelling of early human brain development using optical projection tomography

Kerwin J, Scott M, Sharpe J, Puelles L, Robson SC, Martinez-de-la-Torre M, Ferran JL, Feng GJ, Baldock R, Strachan T, Davidson D, Lindsay S

BMC NEUROSCIENCE, 2004

doi:10.1186/1471-2202-5-27.

Optical projection tomography.

Sharpe J

Annual review of biomedical engineering, 2004

doi:10.1146/annurev.bioeng.6.040803.140210.

Widespread tangential dispersion and extensive cell death during early neurogenesis in the mouse neocortex

Wilkie AL, Jordan SA, Sharpe JA, Price DJ, Jackson IJ

DEVELOPMENTAL BIOLOGY, 2004

doi:10.1016/j.ydbio.2003.11.006.

Optical projection tomography as a new tool for studying embryo anatomy

Sharpe J

JOURNAL OF ANATOMY, 2003

doi:10.1046/j.1469-7580.2003.00155.x.

Optical projection tomography as a tool for 3D microscopy and gene expression studies

Sharpe J, Ahlgren U, Perry P, Hill B, Ross A, Hecksher-Sorensen J, Baldock R, Davidson D

SCIENCE, 2002

doi:10.1126/science.1068206.

3D confocal reconstruction of gene expression in mouse

Hecksher-Sorensen J, Sharpe J

MECHANISMS OF DEVELOPMENT, 2001

doi:10.1016/S0925-4773(00)00508-6.

Identification of Sonic hedgehog as a candidate gene responsible for the polydactylous mouse mutant Sasquatch.

Sharpe J, Lettice L, Hecksher-Sorensen J, Fox M, Hill R, Krumlauf R

CURRENT BIOLOGY, 1999

doi:10.1016/S0960-9822(99)80022-0.

Selectivity, sharing and competitive interactions in the regulation of Hoxb genes

Sharpe J, Nonchev S, Gould A, Whiting J, Krumlauf R

EMBO JOURNAL, 1998

doi:10.1093/emboj/17.6.1788.

Reprogramming Hox expression in the vertebrate hindbrain: Influence of paraxial mesoderm and rhombomere transposition

Itasaki N, Sharpe J, Morrison A, Krumlauf R

NEURON, 1996

doi:10.1016/S0896-6273(00)80069-0.

Structure, evolution and expression of the mitochondrial ADP/ATP translocator gene from Chlamydomonas reinhardtii.

Sharpe JA, Day A

Molecular & general genetics : MGG, 1993

doi:10.1007/BF00282794.