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Shreya Ghosh

13 November 2024 Illustration showing a human gut floating over a scale resting on a microchip labelled ‘AI’. The two sides of the scale show a varying number of bacteria, shown against a backdrop of 0s and 1s.

Microbial load can influence disease associations

Science & Technology Scientists have developed a new machine-learning model to predict microbial load — the density of microbes in our guts — and used it to demonstrate how microbial load plays an important role in disease-microbiome associations.

2024

science-technology

5 September 2024 Male scientist standing in front of a set of stairs.

Promoting impact-driven science

People & Perspectives PROMETHEUS is an EMBL-born grassroots initiative to promote and optimise impact-driven science.

2024

people-perspectives

31 July 2024 Silhouette of gastrointestinal track alongside an illustrator's representation of the carcinogens and antibiotics that seem to be affected by the gut microbiome

Gut microbes implicated in bladder cancer

Science & Technology Study shows that gut bacteria can metabolise carcinogens and cause them to accumulate in distant organs, leading to tumour development.

2024

science-technology

18 June 2024 A progression of three images against a blue/purple background. Each image shows a simulated mouse embryo inner cell mass with two types of cells marked in pink and green respectively. From the first to the third image, the pink cells slowly move from the outer edge to the inside of the mass.

Minecraft-ing our way into studying cell sorting

Science & Technology A theoretical model involving tiny Minecraft-like cubes can help us understand dynamic biological processes, such as cell sorting in embryos.

2024

science-technology

22 May 2024 A sphere with two separated halves; the left half is blue and depicts chromosomes separating along spindles inside multiple nuclei, while the right half is orange, depicting a single set of chromosomes and a spindle with no nuclear envelope visible.

Exploring diversity in cell division

Science & Technology New research by EMBL scientists shows how different modes of cell division used by animals and fungi might have evolved to support diverse life cycles.

2024

science-technology

11 March 2024 Casting new light on gene regulation in development

Casting new light on gene regulation in development

Science & Technology New research from EMBL Heidelberg shows how cells in developing embryos undergo a major shift in the way they regulate gene expression as they mature and differentiate.

2024

sciencescience-technology

8 March 2024 Collage of six images showing scientists and science professionals during the TREC expedition, with a banner saying “International Women’s Day 2024” and the TREC expedition logo.

Insights and wisdom from the women of TREC

Lab MattersPeople & Perspectives On International Women’s Day 2024, we hear from some of the women who have been working tirelessly in the field and behind the scenes as part of the Traversing European Coastlines (TREC) expedition.

2024

lab-matterspeople-perspectives

19 February 2024 Collage of nine pictures with seven photographs showing expedition members sampling and engaging in public outreach activities, and two photos showing EMBL’s new mobile labs.

TREC in 2024: bringing it home

Science & Technology The Traversing European Coastlines (TREC) expedition prepares to begin its next phase of sampling, with stops in Spain, Greece, Italy, and beyond.

2024

sciencescience-technology

23 November 2023 Photographs of two scientists on a decorative background

ERC Consolidator Grants awarded to two EMBL researchers

EMBL AnnouncementsLab Matters Alba Diz-Muñoz and Arnaud Krebs from EMBL Heidelberg have received grants to work on projects that aim, respectively, to understand the cellular mechanics that control cell division and investigate the regulatory networks that govern transcription factor function.

2023

embl-announcementslab-matters

16 November 2023

EMBLetc. issue 101 published

EMBL AnnouncementsLab Matters The newest issue of our online magazine dives deep into a critical research direction in developmental biology, structures of promiscuous proteins, EMBL’s newest service offerings in field research, and much, much more.

2023

embl-announcementslab-matters

15 November 2023 A truck bearing the TREC mobile services logo and illustration on its side.

Taking science on the road

EMBLetc With the new advanced mobile laboratory, EMBL is taking its service offerings to new heights, bringing cutting-edge life science technologies to the field in a way never seen before.

2023

26 October 2023 Photographs of three scientists on a decorative blue background

EMBL scientists receive prestigious ERC Synergy Grants

EMBL Announcements Jan Kosinski, Julia Mahamid, and Georg Zeller have received grants to enable ambitious projects aimed at mapping the cellular protein synthesis machinery in context and understanding complex host-microbiome interactions, respectively.

2023

embl-announcementsscience

17 October 2023 Pill icons representing different antibiotic classes are seen exerting their effects on a bacterium, whose cell wall, membrane, and protein synthesis machinery (two different classes) can be seen as potential targets. Curved lines connect the pills to each other, representing synergies in drug interactions. More bacteria can be seen in the background.

Fighting antimicrobial resistance with new drug combinations

Science & Technology In an extensive investigation, EMBL researchers have tested over 10,000 drug combinations against some of the leading pathogenic bacteria carrying antimicrobial resistance and causing mortality. 

2023

sciencescience-technology

13 October 2023 Scientific illustration showing various model organisms used to study developmental plasticity and a series of concentric circles representing adaptability of interactions.

Understanding developmental plasticity in time and space

Lab MattersScience & Technology A two-week practical course introduced participants to the intricacies of studying the dynamic interplay between organisms and their changing environment and how it impacts development and evolution.

2023

lab-mattersscience-technology

13 September 2023 Magenta and green sombrero-shaped object with grey lines beyond it sits against a black background

Understanding how cells avoid obstacles

Science & Technology EMBL researchers have identified a novel mechanism that allows cells to sense obstacles in their path and avoid them while navigating complex environments.

2023

sciencescience-technology

22 August 2023 Polaroid style shot of Sergiy Avilov, mentioning the years he was at EMBL

After EMBL: Sergiy Avilov

People & Perspectives Ukrainian scientist Sergiy Avilov uses the microscopy skills and scientific network he built at EMBL in his current role heading the Imaging Facility at the Max Planck Institute of Immunobiology and Epigenetics.

2023

alumnipeople-perspectives

3 August 2023 A male scientist working inside a trailer fitted with scientific instruments (left). On the right, the mobile lab trailer can be seen outside a large building in Sweden.

Bringing advanced life science technologies to the field

Lab MattersScience & Technology EMBL’s newly deployed Advanced Mobile Laboratory (AML) is bringing cutting-edge technologies to the European coast to help researchers study ‘life in context’.

2023

lab-mattersscience-technology

15 May 2023 Science illustration representing research on organoids, organs-on-chip and human health. The image shows an abstract composition of several elements referring to the tools and some areas of research covered at EMBL Barcelona, featured on the cover of the 100th issue of EMBL etc.

100th issue of EMBLetc. published

EMBL AnnouncementsLab Matters First published in 1999 as a black-and-white printed newsletter for EMBL staff and alumni, EMBLetc. has undergone many transformations in its 24 years of existence.

2023

embl-announcementslab-matters

15 May 2023 Science illustration representing research on organoids, organs-on-chip and human health. The image shows an abstract composition of several elements referring to the tools and some areas of research covered at EMBL Barcelona, featured on the cover of the 100th issue of EMBL etc.

Celebrating 100 issues of EMBLetc.

EMBLetc First published in 1999 as a black-and-white printed newsletter for EMBL staff and alumni, EMBLetc. has undergone many transformations in its 24 years of existence.

2023

15 May 2023 A computer showing the EMBLetc. homepage open, with a few EMBLetc. magazines and postcards nearby.

A trip down memory lane

EMBLetc EMBLetc., the online magazine of Europe’s life sciences laboratory, celebrates its 24th birthday with its 100th issue. We took a walk through the past issues of this dynamic publication, and here are 10 recurring themes that emerged.

2023

15 May 2023 A section of electron microscopy volume of a Platynereis larvae. Different colours mark different cell groups.

Visualising biology: new tools of the trade

EMBLetc EMBL researchers are pushing the frontiers of big data analysis in biological imaging, allowing scientists to gain a many-layered and multidimensional view of organisms, tissues, and cells in action.

2023

15 May 2023 Researcher holding two sample bags..

In pictures: the story of TREC

EMBLetc EMBL’s newest expedition attempts to answer some of the biggest questions in planetary biology, and will help scientists find solutions to pressing global concerns.

2023

30 March 2023 Science illustration representing two embryos imaged using the Brillouin microscopy technique. The embryo in the front is a mouse embryo at 20h and the one in the back a Phallusia mammillata embryo. A laser beam crosses the samples to analyse tissue stiffness (here represented by acoustic waves).

Shining light on the mechanics of embryo development

Lab MattersScience & Technology A new microscope built by EMBL researchers, based on Brillouin scattering principles, allows scientists to observe the dynamics of mechanical properties inside developing embryos in real time.

2023

lab-matterssciencescience-technology

21 March 2023 Male scientist in blue shirt standing in front of a building with glass doors.

Welcome: Thomas Quail

Lab MattersPeople & Perspectives New group leader Thomas Quail studies the fundamental processes that determine how proteins organise the genome inside a cell.

2023

lab-matterspeople-perspectives

19 January 2023 Cross sections of mouse colon, with mucus stained in blue and nuclei stained in red. The right section has been treated with a mucolytic agent.

Spotlight: Colours of the colon

Lab MattersScience & Technology Mucus present in the mouse colon can be visualised using Alcian blue staining, as imaged here by EMBL predoctoral fellow Linda Decker.

2023

lab-matterspicture-of-the-weekscience-technology

18 November 2022 A molecular illustration in the background showing ribosomes inside a Mycoplasma cell. A banner on top reads 'EMBLetc. Issue 99'

EMBLetc. receives digital-first makeover

EMBL AnnouncementsLab Matters The biannual magazine that highlights EMBL’s research, people, and projects now has a new online home.

2022

embl-announcementslab-matters

16 November 2022 A woman can be seen collecting samples from the shallow ocean, with mountains in the background

From coast to coast and beyond

EMBLetc EMBL researchers conducted a pilot project in Iceland as the final preparatory step before commencing their journey traversing European coastlines.

2022

10 October 2022 Retinal cells can be seen in a cross section. A blue stain (DAPI) marks the cell nuclei, barcoded background cells are visible in green, while a single dopaminergic cell is visible in the centre, marked in orange (Th) and pink (a second barcode).

Light-Seq: from images to sequences in context

Researchers have combined advanced light microscopy with next-generation sequencing to create a method to study cells directly in the context of their native tissues

2022

science

15 September 2022 The foreground shows two yellow pipes representing the human gastrointestinal tract coming together, representing the confluence of donor and recipient gut ecosystems. Bacteria can be seen as green shapes inside the pipes and various kinds of interactions between them are shown symbolically as a mixing of colours.

When microbiomes collide

Science & Technology EMBL researchers used data from over 300 human faecal microbiota transplants to gain an ecological understanding of what happens when two gut microbiomes clash.

2022

sciencescience-technology

7 June 2022 Female scientist photographed in a garden

Welcome: Pascale Cossart

Lab MattersPeople & Perspectives Pascale Cossart, one of the world’s foremost authorities on the biology of Listeria, brings four decades of expertise in intracellular bacterial parasitism to EMBL as a visiting scientist.

2022

lab-matterspeople-perspectives

3 June 2022 he internal structure of a mitotic chromosome is shown with colourful threads representing DNA, one of which is shown being packaged into loops by the condensin protein complex. The background shows mitotic chromosomes in the cellular space

Shaping up the genome for cell division

Science & Technology Researchers have discovered the mechanism by which a family of DNA motor proteins packages loosely arranged strands of DNA into compact individual chromosomes during cell division.

2022

sciencescience-technology

4 March 2022 A gloved hand holds a slide with visible wells containing Matrigel immersed in culture medium. A magnified close-up shows a mouse embryo developing over the course of 48 hours

A 3D culture model to study embryo growth

Science & Technology A recent study by EMBL researchers proposes a new method to grow early embryos in the laboratory. With a 3D culture set-up, scientists can closely monitor the changes embryos undergo around the time of implantation.

2022

sciencescience-technology

25 February 2022 Three colourful overlapping circles arranged in a row, a fruit-fly embryo being visible within each. Small circles within the embryos represent cell lineages.

Converging lenses on embryo development

Science & Technology Researchers from the Furlong group at EMBL have come up with a way to observe the development of fruit-fly embryos simultaneously at the genetic and cellular levels, generating a high-resolution and integrated view of how different cell lineages form.

2022

sciencescience-technology

24 January 2022 Three women are seen in front of a computer, with the electron micrograph of a woodlouse visible on the screens

EMBL Imaging Centre kickstarts training with workshop for undergraduates

Lab Matters The new EMBL Imaging Centre held its first on-site training workshop, introducing undergraduate students to the basics of volume electron microscopy. This marks the first of many opportunities to aid capacity-building in imaging techniques in Europe.

2022

lab-matters

21 January 2022 The cross-section of a cell expressing a green fluorescently tagged protein and illuminated by a blue laser is visible in the foreground, surrounded by a vortex of cells

Cell sorting enters a new dimension

Science & Technology EMBL researchers, in collaboration with BD Biosciences, have demonstrated a new technology that allows rapid image-based sorting of cells. The new technology represents a major upgrade to flow cytometry and has applications in diverse life science fields.

2022

sciencescience-technology

8 December 2021 An illustration of the human gut, with coloured shapes representing bacteria. Three different drugs and drug combinations are shown affecting the bacteria, represented by changes in colour

The impact of drugs on gut microbes is greater than we thought

Science & Technology Researchers studying a massive cohort of European patients have found that commonly prescribed drugs for cardiometabolic disorders can have long-term effects on the gut microbiome. Such effects can complicate the understanding of how disease affects the microbiome and must be taken into…

2021

sciencescience-technology

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