Connections EMBL and its partners have received funding from the European Commission for two new Twinning Projects, which will build expertise and research capacity in its member states.
2024
connections
Blog post by Eleni Tzampatzopoulou, EMBL-EBI Impact Manager In summer 2024, EMBL-EBI ran a user survey, inviting our community to let us know how they use the open data resources we jointly manage with our collaborators. With over 2,300 responses from 126 countries, we were delighted by the depth…
2024
announcements
Connections The partnership will address global food security challenges through optimised agricultural research and data-driven innovation.
2024
connections
The Complex Portal – an encyclopaedic resource of macromolecular complexes from key model organisms – has expanded its coverage of the Human Complexome. This includes: To find out more, read the new paper entitled Complex Portal 2025: Predicted human complexes and enhanced visualisation tools…
2024
uncategorizedupdates-from-data-resources
Science & Technology The introduction of computational methods in biology opened up an entirely new world of insights and breakthroughs. Over the last several decades, EMBL has been at the forefront of discoveries and innovations that have not only propelled the field forward but also opened up access to bioinformatics…
2024
science-technology
The most comprehensive map of the developing human thymus sheds light on how immune responses are built and maintained during early life
2024
announcements
People & Perspectives Public Engagement Officer Briony Jackson is building lasting relationships with local communities to make science accessible and engaging for all.
2024
people-perspectivesperspectives
The v11.28 DECIPHER release is out now. Find out about the new features and improvements.
2024
updates-from-data-resources
In the era of data-driven biology, integrating information from different resources is essential yet often challenging. The BioChemGraph project addresses this challenge by creating infrastructure that consolidates structural, functional, and biochemical annotations for small molecules and their…
2024
updates-from-data-resources
InterPro version 102.0 and InterProScan 5.70-102.0 are now available.
2024
updates-from-data-resources
Ensembl 113 brings major gene and regulatory feature annotation updates in Homo sapiens (human) and Mus musculus (mouse).
2024
updates-from-data-resources
Researchers uncover that DNA changes that cause cancer drug resistance can be grouped into four categories, and identify possible new therapeutic targets.
2024
announcements
Science & Technology Creators of AI system AlphaFold receive 2024 Nobel Prize for Chemistry.
2024
sciencescience-technology
Science & Technology The prize was awarded to John J. Hopfield, Princeton University, USA, and Geoffrey Hinton, University of Toronto, Canada, for their seminal contributions to the foundational methods that enabled the development of machine learning.
2024
science-technology
EMBL-EBI’s microbiome data resource MGnify produces a valuable trove of protein sequence data through its ongoing analysis of microbiome derived data. Two new MGnify Proteins web resources make this dataset easily accessible and searchable, both for large queries across the entire database…
2024
updates-from-data-resources
EMBL-EBI and colleagues from other 11 institutes commit to pathogen data sharing project.
2024
announcements
Science & Technology Addition of data from more diverse populations to the Polygenic Score (PGS) Catalog and a new software tool for PGS calculation could help produce more equitable disease risk predictions.
2024
science-technologytechnology-and-innovation
New datasets The release has 381 single-cell RNA-Seq experiments, consisting of more than 13.5 million cells from 21 different species to explore in the Single Cell Expression Atlas (SCEA). The resource now includes an entirely new class of data – externally analysed data, marked with an…
2024
updates-from-data-resources
People & Perspectives EMBL-EBI Postdoctoral researcher Iguaracy Pinheiro de Sousa is using bioinformatics to support the development of better organoids.
2024
people-perspectivesperspectives
Science & Technology EMBL-EBI data resources help advance biodiversity and climate change research by enabling scientists to study species interactions, evolutionary processes, ecosystem health, and more.
2024
science-technologytechnology-and-innovation
Traditional sequence search methods are fast and efficient but rely solely on comparing amino acid sequences. This approach can miss crucial insights because proteins with similar functions can have vastly different sequences. Although their sequences have diverged, these proteins often retain 3D…
2024
updates-from-data-resources
People & Perspectives EMBL-EBI alumnus Alvis Brazma reflects on how mathematics and mountaineering have shaped his life and why keeping things simple in bioinformatics is key.
2024
people-perspectivesperspectives
People & Perspectives EMBL-EBI’s new Head of Applications will use his expertise in cloud infrastructure and security to support the institute’s open data resources.
2024
people-perspectivesperspectives
Science & Technology Using machine learning to analyse the genetic factors behind early clinical trial termination, researchers find a link between genetic evidence and trial outcome.
2024
research-highlightsscience-technology
The v11.27 DECIPHER release is out now. Find out about the new features and improvements.
2024
updates-from-data-resources
People & Perspectives ARISE fellow Melanie Schneider shares how she uncovered a new interest in research infrastructures and supporting discovery.
2024
people-perspectivesperspectives
People & Perspectives Kim Gurwitz talks about her role as Scientific Training Lead at EMBL-EBI and how collaborative projects for bioinformatics training support researchers and service providers in making the most of publicly available data.
2024
people-perspectivesperspectives
Science & Technology The dynamic world of proteomics is shaping the future of personalised medicine, but some obstacles stand in the way
2024
perspectivesscience-technology
Lab Matters What makes EMBL unique? Among many things, it’s the infinite curiosity of its community.
2024
lab-matters
People & Perspectives Ewan Birney reflects on his time at EMBL and the development of the organisation through a commitment to open data and nurturing scientific talent.
2024
people-perspectivesperspectives
People & Perspectives The new Team Leader for Human Genomics at EMBL-EBI shares how curiosity and maths shaped her career and what it takes to be a community builder.
2024
people-perspectivesperspectives
EMBL Announcements Researchers explore genetic diversity found in ancient environmental DNA to help modern agricultural practices.
2024
announcementsembl-announcements
IntAct 247 release is now public with over 1.5 million binary interaction evidences
2024
updates-from-data-resources
Science & Technology EMBL-EBI data resource helps scientists upcycle animal by-products.
2024
perspectivesscience-technology
A behind-the-scenes look at EMBL-EBI's in-house archive that supports major open data resources and ingests record amounts of data
2024
technology-and-innovation
The latest DECIPHER release includes AlphaMissense scores, links to the Open Targets Platform and more.
2024
updates-from-data-resources
Science & Technology Large-scale study uses data from Danish health registries to predict individual risks of developing cancer
2024
research-highlightsscience-technology
The integration enables researchers to easily access AI-generated scores estimating how likely genetic variants are to be pathogenic
2024
technology-and-innovation
EMBL-EBI asks users to fill in a services survey to help shape the future of the open data resources managed by the institute
2024
announcements
The latest Expression Atlas 40 release is now live, containing new RNA-seq datasets, including a featured experiment resulting from a collaboration with Genotype Tissue Expression (GTEx) project as well as new proteomics data derived from our collaboration with PRIDE. In total, this release…
2024
updates-from-data-resources
People & Perspectives EMBL-EBI's new Head of Research shares his plans and priorities.
2024
people-perspectivesperspectives
Ensembl 112 and the corresponding release of Ensembl Genomes 59 has released. This includes exciting new fish species, many more drosophila species and new VEP updates.
2024
updates-from-data-resources
People & Perspectives María Cerezo talks about her role as Scientific Curator, how she combines it with her position as co-chair of the Staff Association, and what she believes has been EMBL's biggest achievement in its first 50 years.
2024
people-perspectivesperspectives
EMBL-EBI's Senior Management Team announces new appointment and title changes.
2024
announcements
EMBL Announcements MSD joins as the latest partner in the Open Targets consortium, enhancing the initiative’s collaborative efforts in drug discovery.
2024
announcementsembl-announcements
Science & Technology Experts in quantum computing and genomics to develop new methods and algorithms to process biological data.
2024
announcementsscience-technology
EMBL Announcements Data obtained through cryogenic sample electron tomography (cryo-ET) are openly available in the new Electron Microscopy Public Image Archive (EMPIAR) cryo-ET tomography browser.
2024
announcementsembl-announcements
The latest DECIPHER update, version 11.25, introduces new key features including the integration of functional data from multiplexed assays of variant effect (MAVEs) and much more.
2024
updates-from-data-resources
Science & Technology New study uncovers the potential of immunotherapy in preventing breast cancer and creates the openly available Human Breast Cell Atlas.
2024
research-highlightssciencescience-technology
The SARS-CoV-2 Data Hubs are a set of tools coupled with infrastructure that support four components: the submission, analysis, presentation and visualisation of SARS-CoV-2 raw read data, and its resulting analyses. What makes Data Hubs attractive is a unique set of features: A new publication in…
2024
updates-from-data-resources
People & Perspectives Data standards that have been silently enabling discovery in the life sciences for decades are now making AI advances possible.
2024
people-perspectivesperspectivesscience
AI annotations added to the SureChEMBL database increase the depth of data made available to users.
2024
sciencetechnology-and-innovation
People & Perspectives Team Leader Sameer Velankar on why accessible training is key for AlphaFold and AI tools more generally.
2024
people-perspectivesperspectivesscience
The MGnify data resource for microbiome data has launched the latest MGnify Genomes catalogue comprising 112,951 genomes derived from mouse gut datasets, represented by 2,847 species-level cluster representative genomes. This catalogue was generated as part of our work with the MRC funded…
2024
updates-from-data-resources
Science & Technology Plasmodium falciparum, a malaria parasite, uses gene conversion to produce genetic diversity in two surface protein genes targeted by the human immune system.
2024
announcementssciencescience-technology
Science & Technology An international team of researchers aim to combine social determinants of health with genomics, immune profiling, and exposomics data to tackle cancer inequities at an unprecedented scale.
2024
announcementssciencescience-technology
The Federated European Genome-phenome Archive (FEGA) marks a significant milestone with the release of its first datasets.
2024
announcements
Version 11.24 of DECIPHER introduces a new ACMG/AMP pathogenicity interface for sequence variant predictions, displays ClinGen Variant Curation Expert Panel recommendations on gene pages, and updates ACMG secondary finding information to v3.2.
2024
updates-from-data-resources
Lab MattersPeople & Perspectives Jacqueline shares her experience of EMBL's international PhD programme.
2024
lab-matterspeople-perspectives
New Europe PMC tools support preprint review discovery
2024
updates-from-data-resources
Lab MattersPeople & Perspectives Kyle Morris joins EMBL-EBI as Electron Microscopy Data Bank (EMDB) Team Leader.
2024
lab-matterspeople-perspectives
Streamlining proteomics data access for machine learning applications.
2024
sciencetechnology-and-innovation
The Ensembl 111 features a range of new Ensembl VEP plugins and updated agricultural, fish, plant and metazoa species.
2024
updates-from-data-resources
A $3.8 million grant from the Gordon and Betty Moore Foundation will help researchers lay groundwork for the Biodiversity Cell Atlas.
2024
announcements
Science & Technology Researchers reveal that healthy lung development hinges on immune-epithelial crosstalk, with implications for respiratory diseases.
2023
research-highlightsscience-technology
UK Research and Innovation (UKRI) has confirmed £80.7 million of funding for EMBL’s European Bioinformatics Institute (EMBL-EBI). The funding comes from the UKRI Infrastructure Fund and will be distributed over the course of six years. It is set to help EMBL-EBI transform its technical…
2023
announcements
Science & Technology The new initiative brings together genomic data from various biodiversity projects to aid conservation and biodiversity efforts.
2023
announcementssciencescience-technology
Two new data portals are set to support infectious disease monitoring and research across Europe; the Swedish Pathogens Data Portal and the Netherlands COVID-19 Data Portal.
2023
updates-from-data-resources
Leading charities Children with Cancer UK and Cancer Research UK will co-fund a major £5.5 million research programme to advance precision medicine for relapsed childhood cancers.
2023
announcements
Large language models are changing the way we carry out scientific data curation, annotation, and research, setting the stage for a more efficient understanding of scientific literature
2023
technology-and-innovation
Where to start when thinking about the sustainability of informatics projects
2023
perspectives
InterPro version 97.0 and InterProScan 5.64-97.0 are now available. InterPro now features hundreds of new methods integrated from partner databases, and InterProScan draws on over 40000 entries.
2023
updates-from-data-resources
Users no longer need to download large datasets with the new galleries feature
2023
updates-from-data-resources
As science increasingly relies on big data and AI tools, the carbon footprint of computational work is on the rise
2023
perspectives
In response to user community demands, the AlphaFold Protein Structure database has introduced sequence-based search and cluster members.
2023
updates-from-data-resources
The Lees group develops a tool that can scale up bacterial genome annotation.
2023
research-highlights
EMBL Announcements EMBL receives the German AI prize awarded for outstanding services to the research and development as well as application and commercialisation of artificial intelligence (AI) in life science research.
2023
embl-announcementsscience
InterPro version 96.0 and InterProScan 5.64-96.0 are now available.
2023
updates-from-data-resources
Lab MattersPeople & Perspectives PhD student Valentina Lorenzi is using single-cell sequencing data to create a map of the developing human reproductive system.
2023
lab-matterspeople-perspectivesperspectives
Science & Technology Enzymes constitute a large fraction of genomes – 20% in humans – which makes them a very important part of life. Despite decades of studies and a rich literature dedicated to understanding the reaction mechanisms of enzymes, the rules of enzyme catalysis are still not fully clear. A new…
2023
science-technologytechnology-and-innovation
Lab MattersPeople & Perspectives David Hulcoop discusses how his experience bridging organisational cultures will help address critical challenges in drug discovery and target selection at Open Targets.
2023
announcementslab-matterspeople-perspectives
Science & Technology Ensembl Variant Effect Predictor integrates Google DeepMind’s new AlphaMissense Database for better predictions of genetic variant pathogenicity.
2023
science-technologytechnology-and-innovation
Science & Technology New research improves understanding of the molecular mechanisms behind why some cancers respond to immunotherapy and others don't.
2023
research-highlightssciencescience-technology
Science & Technology Researchers use the AlphaFold database and Foldseek Cluster algorithm to analyse millions of predicted protein structures and offer new insights into protein evolution.
2023
research-highlightssciencescience-technology
EMBL-EBI’s Deputy Head of Research Virginie Uhlmann delves into the institute’s unique research landscape and the essential qualities for effective leadership in this field
2023
perspectives
People & Perspectives Experience in data management and coordination has enabled EMBL alumna Laura Clarke to pursue a career in AI development.
2023
people-perspectivesperspectivesscience
People & Perspectives EMBL-EBI Senior Scientist Rob Finn explains why data coordination and sharing are fundamental for a sustainable blue economy.
2023
people-perspectivesperspectivesscience
Science & Technology SComatic enables researchers to link genotype to phenotype using only single-cell profiling data
2023
research-highlightssciencescience-technology
Lab MattersPeople & Perspectives By upskilling researchers on bioinformatics skills and tools, EMBL alumna Emily Perry is helping to make genomic medicine more accessible.
2023
lab-matterspeople-perspectivesperspectives
Ensembl 110 and Ensembl Genomes 57 have introduced in-house prokaryotic gene annotation across genomes available in Ensembl Bacteria. Since its inception, Ensembl Bacteria has imported user-submitted annotations from the International Nucleotide Sequence Database Collaboration (INSDC) for…
2023
updates-from-data-resources
The latest Expression Atlas release is now live and contains a wider range of RNA-seq and proteomics datasets.
2023
updates-from-data-resources
The GA4GH standard refget quietly helps decipher millions of genomes sequenced worldwide, and it just got better.
2023
technology-and-innovation
Ensembl 100 release brings exciting updates, such as the addition of regulation data to 5 animal genomes studied extensively in agriculture.
2023
updates-from-data-resources
We are excited to announce the latest releases of IntAct and Complex Portal. IntAct 244 highlights Complex Portal 244 highlights
2023
updates-from-data-resources
EMBL AnnouncementsLab Matters Construction begins on EMBL-EBI's new building named after Janet Thornton.
2023
announcementsembl-announcementslab-matters
InterPro version 95.0 and InterProScan 5.63-95.0 are now available! InterPro now features hundreds of new methods integrated from partner databases, and InterProScan draws on over 39000 entries. InterPro version 95.0 – new features include: InterPro 95.0 covers 81.7% of UniProt Knowledgebase…
2023
updates-from-data-resources
EMBL Announcements Closer collaborations with EMBL-EBI data resources set to further develop and grow this unique rare disease platform.
2023
announcementsembl-announcementsscience
Science & Technology Enabling researchers worldwide to share and analyse pathogen data generated across the world
2023
sciencescience-technologytechnology-and-innovation
EMBL Announcements Coming from a pharmaceutical industry background, David Hulcoop is set to take over as Executive Director of the public-private partnership Open Targets.
2023
announcementsembl-announcements
Better search for Europe PMC funder grants with ROR IDs
2023
updates-from-data-resources
New framework to improve the FAIRness of clinical and molecular datasets
2023
perspectives
Science & Technology HoloFood, the first consistent collection of multiomic data about chicken and salmon gut microbiomes, set to enable the development of better animal feeds.
2023
sciencescience-technologytechnology-and-innovation
The AlphaFold Database boasts improved user experience, including better search filters and an improved 3D viewer.
2023
updates-from-data-resources
Science & Technology EMBL-EBI data resources are being used to deliver thousands of genetic diagnostics to patients every month.
2023
perspectivessciencescience-technology
Lab MattersPeople & Perspectives In recognition of Janet Thornton’s retirement, we look back at some of her biggest accomplishments shaping the field of bioinformatics.
2023
announcementslab-matterspeople-perspectives
Science & Technology A new tool for the interpretation of missense variation in humans – ProtVar – will help enable drug discovery.
2023
sciencescience-technologytechnology-and-innovation
ConnectionsLab Matters EMBL researchers and collaborators have begun an impactful innovation-development journey, thanks to a European Commission ‘IMAGINE’ grant.
2023
connectionslab-matters
Connections The PLAST-CELL project aims to understanding cancer progression by quantifying a cancer cell’s ability to respond to environmental stress that threatens its survival
2023
connectionstechnology-and-innovation
Lab MattersPeople & Perspectives Postdoctoral researcher Carolin Sauer is leveraging long-read sequencing to develop new detection methods for various cancers.
2023
lab-matterspeople-perspectivesresearch-highlights
InterPro 94.0 features hundreds of new methods integrated from partner databases, and InterProScan draws on over 38,000 entries.
2023
updates-from-data-resources
BioImage Archive Team Leader Matthew Hartley shares his experience and tips for people interested in managing a bioinformatics core facility.
2023
technology-and-innovation
Science & Technology Understanding chromothripsis offers insights into how cancer develops.
2023
research-highlightsscience-technology
Science & Technology The human pangenome – one of the most complete collections of genome sequences released so far – captures rich human diversity.
2023
announcementssciencescience-technology
Lab MattersScience & Technology EMBL-EBI is making a key contribution to a historic effort to understand the function of every human gene
2023
announcementslab-mattersscience-technology
Lab MattersPeople & Perspectives On the 20th anniversary of the Human Genome Project, we look back at its history, wonder and potential.
2023
lab-matterspeople-perspectivesperspectives
People & Perspectives As a postdoc Alex Almeida used bioinformatics to push the boundaries of what we know about the gut microbiome. Here, Almeida explains how his time at EMBL-EBI generated new research avenues, and how the skills and connections from his postdoc prepared him for leading his own research group at the…
2023
people-perspectivesperspectives
Science & Technology WormBase ParaSite release 18 adds largest number of new genomes and annotations since launch, as well as full integration with AlphaFold.
2023
science-technologyupdates-from-data-resources
Lab MattersPeople & Perspectives Scientists have the technology to edit the human genome. But when should they, and who contributes to these decisions?
2023
lab-matterspeople-perspectivesperspectives
Science & Technology EMBL-EBI researchers have developed a new tool capable of performing state-of-the-art phylogenetic inference on larger datasets than previously thought possible.
2023
research-highlightssciencescience-technology
Connections Darwin Tree of Life project improves bioinformatics tools for biodiversity data analysis
2023
connectionstechnology-and-innovation
The European Nucleotide Archive database introduces mandatory spatiotemporal metadata for data submissions.
2023
updates-from-data-resources
Using long-read sequencing and machine learning approaches, EMBL alumna Lara Urban is making a difference in the field of One Health.
2023
perspectives
EMBL-EBI's metagenomics data resource increases in size and supports groundbreaking AI tools for protein structure prediction.
2023
updates-from-data-resources
EMBL-EBI researchers use UK Biobank data to uncover new information about rare diseases of the eye.
2023
research-highlightsscience
Meet some of our equality, diversity, and inclusion champions and find out how they’re making EMBL-EBI a better place to work
2023
announcements
InterPro now features hundreds of new methods integrated from partner databases, and InterProScan draws on over 38,000 entries. InterPro version 93.0 InterPro 93.0 integrates 300 new methods from the CDD (261), PANTHER (12), PROSITE profiles (17), SMART (9), TIGRFAMs (1) databases, and covers 81.7%…
2023
updates-from-data-resources
As major biodiversity projects ramp up, EMBL-EBI enables genomic data sharing for all species.
2023
perspectivesscience
The Single Cell Expression Atlas (SCEA) now includes more datasets and species.
2023
updates-from-data-resources
Why open data from model organisms is essential for rare disease research.
2023
perspectivesscience
The Open Global Data Citation Corpus will become a central place for research data citations, and include accession numbers supplied by Europe PMC.
2023
announcements
Researchers create a network of interacting proteins – or interactome – to aid drug discovery.
2023
research-highlightsscience
EMBL-EBI’s Software Development and Operations team is delighted to announce the launch of a brand-new Job Dispatcher website, currently in development. The updated website provides a landing page for the Job Dispatcher services, making it easier for users to find and navigate services…
2023
updates-from-data-resources
Lab MattersPeople & Perspectives Jo McEntyre talks about data services, open data and a new era for research assessment.
2023
lab-matterspeople-perspectivesperspectives
Lab MattersScience & Technology EMBL is one of the partners of this project that aims to accelerate drug discovery and development, bringing in expertise from EMBL Grenoble and EMBL-EBI.
2023
lab-mattersscience-technology
EMBL-EBI congratulates Matt Hurles on being appointed as the new Director of the Wellcome Sanger Institute.
2023
announcements
Open data played a pivotal role in the development of the AlphaFold AI. The same open principles now apply to AlphaFold predictions.
2023
perspectivesscience
Latest Ensembl and Ensembl Genomes releases bring updates to donkey and horse assemblies, and lots of new plants and metazoa.
2023
updates-from-data-resources
Funding awarded for developing tools to harness marine microbiome data for biotechnological applications and ecosystem services.
2023
announcementsscience
Genomic sequencing and big data analysis are two novel technologies driving researchers’ understanding of the complexities of cancer.
2023
perspectivesscience
Aggregating clinical, genomic and functional data from patient-derived xenografts, organoids and cell lines
2023
updates-from-data-resources
Science & Technology Open Targets is using artificial intelligence and machine learning to identify and prioritise drug targets.
2023
sciencescience-technologytechnology-and-innovation
Science & Technology We look back through some of the 2022 highlights from the Darwin Tree of Life project.
2023
perspectivessciencescience-technology
Lab MattersPeople & Perspectives Rob Finn, one of the co-chairs of the Microbial Ecosystems theme, discusses his work, the challenges of multidisciplinary research, and how the theme is already helping to promote the exchange of scientific ideas.
2023
lab-matterspeople-perspectives
InterPro version 92.0 and InterProScan 5.60-92.0 are now available. InterPro now features hundreds of new methods integrated from partner databases, and InterProScan draws on over 38000 entries.
2023
updates-from-data-resources
Science & Technology A new method developed by EMBL-EBI researchers helps to streamline nanopore sequencing in real-time.
2023
research-highlightssciencescience-technology
Open data resources that enable global research and development recognised by the Global Biodata Coalition.
2022
announcementsscience
Researchers have genetically profiled nearly 200,000 cells from lungs, mapping their precise locations in tissue to discover an unexpected new immune niche in our airways.
2022
research-highlights
The first cohort study linking data across categories was recently added on the Pathogens Portal Cohort Browser and is also accessible from the BioSamples browser. This pilot study comes from Erasmus Medical Centre through the ReCoDID project, one of the COVID-19 Data Platform supporting…
2022
updates-from-data-resources
Andy Cafferkey takes on strategic role to help the institute respond to increasing demands from the global life science community.
2022
announcements
Unveiling a useful tool for understanding human lung development.
2022
research-highlightsscience
EMBL-EBI supports new European Commission project set to support the use of genomics in research and healthcare.
2022
announcementsscience
An ambitious project to sequence the genomes of all known species of euglenoids will drive research on biofuels and sustainable foods.
2022
announcements
Our experts discuss the importance of open science for food security and preserving global biodiversity.
2022
perspectivesscience
Researchers have created a tool that maps in previously unseen detail how breast cancer develops and spreads.
2022
research-highlightsscience
Researchers use social media to share findings on how useful AlphaFold predictions are for different applications.
2022
research-highlightsscience
Researchers across EMBL are helping to make artificial intelligence (AI) models for bioimaging analysis interoperable and openly available to the scientific community.
2022
announcementsscience
Virginie Uhlmann will support the Interim Head of Research in managing the institute's computational research groups.
2022
announcements
NIH BRAIN Initiative to fund brain atlases, network coordination, and knowledge sharing to explore brain function research.
2022
announcementsscience
You can now superpose AlphaFold models onto PDB structures at the touch of a button using the PDBe-KB aggregated views of proteins.
2022
updates-from-data-resources
We are pleased to announce the release of Ensembl 108, and the corresponding release of Ensembl Genomes 55 featuring changes in the human default tracks, new genomes in Ensembl Plants and Ensembl Metazoa, and the addition of mitochondrial annotation for Tasmanian devil. Genome assemblies and…
2022
updates-from-data-resources
We are pleased to announce the release of InterPro 91.0 and InterProScan 5.59-91.0
2022
updates-from-data-resources
Data continues to be available in BioStudies.
2022
updates-from-data-resources
Over 40 million protein annotations have been added to the UniProt database using a Google Research natural language processing model.
2022
technology-and-innovation
EMBL-EBI’s MGnify data resource helps researchers find enzymes for novel applications.
2022
announcementsscience
European experts gather to launch a project that aims to characterise and conserve life on Earth using DNA data.
2022
announcementsscience
The Royal Microscopical Society recognises Ardan Patwardhan’s contributions to the field of electron microscopy.
2022
announcements
Connections The Federated EGA is set to improve access to sensitive human data in a safe and secure way.
2022
announcementsconnectionsscience
The United Kingdom is a founding member of EMBL, and has hosted EMBL’s European Bioinformatics Institute since 1994. We recognise that the passing of Her Majesty Queen Elizabeth II will have a profound impact on the country, and we extend our deepest sympathies to the Royal Family at this…
2022
announcements
Science & Technology Machine learning has helped researchers uncover new insights into how bacteria infect host cells.
2022
research-highlightssciencescience-technology
Science & Technology AlphaFold database offers a look at 3D protein universe.
2022
sciencescience-technologytechnology-and-innovation
Connections The first meeting of the Latvian Bioinformatics Forum points towards an even brighter future for the country’s role in European life sciences
2022
connectionsevents
Science & Technology Scientists identify previously unexplored gene segments to be added to human genome databases.
2022
research-highlightssciencescience-technology
Using powerful data visualisation and interactive search results across datasets allows users to explore hypotheses across a range of metadata, and discover new insights backed by expertly curated, consistently reanalysed single cell sequencing data. Searching for metadata, allows a powerful…
2022
updates-from-data-resources
Funding set to support data resources for key areas of antimicrobial resistance, sustainable agriculture and biodiversity loss
2022
announcements
On 30 September 2022 the ArrayExpress interface will close. All datasets have now been migrated from ArrayExpress into the BioStudies ArrayExpress collection
2022
updates-from-data-resources
ConnectionsLab Matters The African BioGenome Project and EMBL have signed a Memorandum of Understanding to support each other in building genomics and bioinformatics capacity across Africa
2022
announcementsconnectionslab-matters
Science & Technology Researchers discover how DNA mutations change blood cell production and how this relates to ageing and cancer development.
2022
research-highlightssciencescience-technology
Science & Technology Researchers in the Ensembl team are making the most of machine learning methods to speed up genome annotation pipelines
2022
sciencescience-technologytechnology-and-innovation
New dataset of predicted protein complexes accessible through 3D-Beacons Network.
2022
updates-from-data-resources
Science & Technology Virginie Uhlmann shares her tips for using deep learning for bioimage analysis in the life sciences.
2022
perspectivessciencescience-technology
The GBC is a coalition of life sciences and biomedical research funders that aims to optimise the funding and management of biodata resources worldwide. The organisation has two priority aims: to better coordinate and share approaches for efficient management and growth of the biodata…
2022
announcements
Science & Technology Researchers from the MANE collaboration bring you the most comprehensive human genome annotation dataset to date.
2022
research-highlightssciencescience-technology
The latest Single Cell Expression Atlas (SCEA) release is here and features collaborations with DiscovAIR and the Fly Cell Atlas
2022
updates-from-data-resources
Science & Technology Researchers lay out a set of principles for open genomic data sharing or pathogens
2022
perspectivesscience-technology
Science & Technology The African BioGenome Project aims to safeguard biodiversity and build bioinformatics capacity across Africa
2022
perspectivessciencescience-technology
New Expression Atlas release features differential-proteomics and baseline-proteomics experiments in collaboration with the PRIDE team at EMBL-EBI. This also includes new baseline DIA proteomics experiments as well as new differential proteomics datasets. To improve reproducibility,…
2022
updates-from-data-resources
Science & Technology Scientists urge the adoption of a sensible international policy for digital sequence information.
2022
announcementssciencescience-technology
Science & Technology DeepMind visits EMBL Heidelberg to discuss current and future implications of Artificial Intelligence for life science research.
2022
sciencescience-technology
Latest AlphaFold database update adds 27 new organisms and almost 200,000 new protein structure predictions relevant to neglected tropical diseases and antimicrobial resistance
2022
updates-from-data-resources
Science & Technology An exploration of where in the world genomics methods are applied and where the data are used.
2022
perspectivessciencescience-technology
Science & Technology On track to reach an ambitious goal of 3,000 genomes sequenced by the end of 2022, what’s next for the Earth Biogenome Project?
2022
announcementssciencescience-technology
Lab MattersPeople & Perspectives Melissa Harrison joins EMBL-EBI as the new Team Leader of Literature Services. We found out more about her plans for open access publishing and Europe PMC.
2022
lab-matterspeople-perspectives
Science & Technology A look back at some of the 2021 highlights from the Darwin Tree of Life partner institutes.
2021
sciencescience-technology
Science & Technology The systematic application of AI in life sciences as in the AlphaFold algorithm for predicting protein structures has been named '2021 Breakthrough of the Year' by Science magazine.
2021
sciencescience-technology
Lab MattersPeople & Perspectives Tudor Groza joins EMBL-EBI as our new Phenomics Team Lead. We found out from Tudor exactly what this new role will entail
2021
lab-matterspeople-perspectives
Science & Technology How genomics, open data, and multidisciplinary science can improve food security.
2021
sciencescience-technology
Science & Technology The GA4GH Data Use Ontology (DUO) supports a data authorisation and access framework to streamline consent to use biomedical data
2021
sciencescience-technology
Science & Technology A vast, curated collection of bacterial genomes is now organised, searchable and open to the community.
2021
sciencescience-technology
Lab MattersScience & Technology Independent study reveals that EMBL-EBI open data resources are critical for the life sciences.
2021
lab-mattersscience-technology
Science & Technology The Darwin Tree of Life project is an unprecedented initiative sequencing 70,000 species
2021
sciencescience-technology
Science & Technology International project uses biomolecular data to improve animal feed and make meat production more sustainable
2021
sciencescience-technology
Science & Technology Using metagenomic data to find novel enzymes for plastic degradation and beyond
2021
sciencescience-technology
Science & Technology The BY-COVID project aims to make infectious disease data, including COVID-19, openly available to everyone.
2021
sciencescience-technology
Science & Technology Profiling M. tuberculosis strains from 27 countries to reveal causes of drug resistance.
2021
sciencescience-technology
Lab MattersPeople & Perspectives Ian Dunham walks us through his career so far including working on the human genome project, seeing his work on the cover of Nature and his current role as Director of Open Targets.
2021
lab-matterspeople-perspectives
Science & Technology Researchers develop a new high-throughput approach to assess the functional significance of protein phosphosites.
2021
sciencescience-technology
Science & Technology Largest in-depth analysis of genomic data tracks the spread of SARS-CoV-2 lineages in England.
2021
sciencescience-technology
Lab Matters Hundreds of school children explore the beauty of proteins through art
2021
lab-matters
Connections 3D-Beacons Network acts as a one-stop shop for protein structures by combining and standardising data from several providers.
2021
connectionsscience
Science & Technology Researchers have combined spatial gene expression information with single-cell genomics data to create a high-resolution atlas of mouse organogenesis.
2021
sciencescience-technology
Science & Technology Partners use AlphaFold, the AI system recognised last year as a solution to the protein structure prediction problem, to release more than 350,000 protein structure predictions including the entire human proteome to the scientific community.
2021
sciencescience-technology
Science & Technology DeepMind and EMBL-EBI to make millions of protein structure predictions freely available to the scientific community.
2021
sciencescience-technology
Science & Technology A discussion of the applications that AlphaFold DB may enable and the possible impact of the resource on science and society.
2021
sciencescience-technology
Science & Technology Researchers establish a framework for identifying new drugs capable of exploiting a cell’s own machinery.
2021
sciencescience-technology
Lab MattersPeople & Perspectives EMBL welcomes Sarah Dyer, the new Non-Vertebrate Genomics Team Leader at EMBL-EBI.
2021
lab-matterspeople-perspectives
Science & Technology New software enables scientists to visualise RNA secondary structures using the world’s largest RNA structure dataset.
2021
sciencescience-technology
EMBL AnnouncementsLab Matters John Marioni, Alex Bateman, and Takashi Hiiragi have been elected to EMBO Membership.
2021
embl-announcementslab-matters
Science & Technology The largest in-depth analysis of genomic surveillance data mapping out the dynamics of 62 lineages of the SARS-CoV-2 virus.
2021
sciencescience-technology
Science & Technology Researchers reveal the best technology for assembling reference genomes.
2021
sciencescience-technology
Science & Technology Researchers identify differences in immune response in asymptomatic COVID-19 cases compared to those with severe symptoms
2021
sciencescience-technology
Science & Technology Researchers have used a metagenomics approach to piece together the genomes of yeasts found in wild lichens.
2021
sciencescience-technology
Connections Scientists from the CABANA project explore how open data is benefiting global research efforts.
2021
connectionsscience
Science & Technology Researchers use large-scale human genetic studies to identify drug targets important for managing COVID-19 in its early stages
2021
sciencescience-technology
Science & Technology Researchers have used human medical and genetic data from UK Biobank to investigate the genetics of age-related diseases
2021
sciencescience-technology
Lab MattersPeople & Perspectives The challenges and opportunities when setting up a global archive for bioimages
2021
lab-matterspeople-perspectives
Science & Technology Thousands of new protein structure models, prected using deep learning, now available to explore
2021
sciencescience-technology
Science & Technology Scientists identify more than 140 000 virus species in the human gut; more than half have never been seen before
2021
sciencescience-technology
Lab Matters Professor Dame Janet Thornton discusses work–life balance, the support she has received during her career, and how organisations can help staff during the COVID-19 pandemic
2021
lab-matters
EMBL AnnouncementsLab Matters Open letter galvanises life science community in support of open COVID-19 data
2021
embl-announcementslab-matters
Science & Technology A new lineage of coronavirus was first identified in the UK, but why is it spreading much more rapidly within the population?
2021
sciencescience-technology
Science & Technology Freshwater sports can cause waterborne infections, but real-time DNA sequencing could help.
2021
sciencescience-technology
People & Perspectives Understanding why disagreement is good for COVID science. EMBL Deputy Director General Ewan Birney offers tips for sorting through the discourse.
2021
people-perspectivesscience
Lab Matters Schoolchildren create exquisite protein-inspired artworks
2020
lab-matters
Science & Technology Despite restrictions, 2020 has been a busy year for the Darwin Tree of Life Project. We take a look at some of this year’s achievements and highlights.
2020
sciencescience-technology
Science & Technology How artificial intelligence can help us solve the mysteries of the protein universe
2020
sciencescience-technology
Connections Microbiomes, plastics, and connectivity – AtlantECO aims to understand the fabric of the Atlantic Ocean.
2020
connectionsscience
Lab MattersScience & Technology Why should researchers make artificial intelligence more transparent and how can they do it?
2020
lab-mattersscience-technology
ConnectionsLab Matters EMBL’s Rupert Lück is engaged in developing the European Open Science Cloud (EOSC): the infrastructure that will support the future of data sharing and analysis in Europe.
2020
connectionslab-matters
Science & Technology Scientists from the Beltrao Group at EMBL-EBI and collaborators identified drug targets common to SARS-CoV-2, SARS-CoV-1, and MERS-CoV, three pathogenic coronaviruses. They also found potential drugs that could be repurposed as COVID-19 treatments, and against emerging coronavirus strains in the…
2020
sciencescience-technology
Lab MattersScience & Technology A decadal roadmap points the way to cell-based medicine for Europe
2020
lab-mattersscience-technology
Science & Technology The Gerstung Group at EMBL-EBI and collaborators have developed a statistical model that analyses genomic data to predict whether a patient has a high or low risk of developing oesophageal cancer.
2020
sciencescience-technology
EMBL AnnouncementsLab Matters EMBL-EBI is one of the eight European institutes involved in the Humanoid Cell Atlas initiative, a new open-access platform that combines single-cell profiling and organoid technology
2020
embl-announcementslab-matters
Lab MattersPeople & Perspectives The Web Development team provides a central source of web design and development for EMBL’s European Bioinformatics Institute (EMBL-EBI). In July, Geetika Malhotra joined the team as their new Head.
2020
lab-matterspeople-perspectives
Science & Technology An international team of scientists involving Ewan Birney's group has investigated the function of a complex mesh of muscle fibres that line the inner surface of the heart.
2020
sciencescience-technology
Science & Technology A global team of researchers including the Flicek Team at EMBL-EBI has partnered up with the Māori tribe Ngātiwai to sequence the genome of the tuatara, a rare reptile endemic to New Zealand.
2020
sciencescience-technology
Science & Technology The human genome harbours about 19 000 protein-coding genes, many of which still have no known function. As scientists unveil the secrets of our DNA, they come across novel genes that they need to refer to using a unique name. The Human Genome Organisation’s Gene Nomenclature Committee (HGNC) at…
2020
sciencescience-technology
Science & Technology Researchers have developed an artificial intelligence algorithm that uses computer vision to analyse tissue samples from cancer patients. The algorithm can distinguish between healthy and cancerous tissues, and can also identify patterns DNA and RNA changes in tumours.
2020
sciencescience-technology
Science & Technology An international team of scientists has collated all known bacterial genomes from the human gut microbiome into a single large database. Their work will allow researchers to explore the links between bacterial genes and proteins, and their effects on human health.
2020
sciencescience-technology
Lab Matters European collaboration receives funding to explore risks and impact of future infectious disease outbreaks.
2020
lab-matters
EMBL AnnouncementsLab Matters This year, EMBO elected 63 new members, including Alexander Aulehla, Group Leader and Senior Scientist at EMBL Heidelberg, and Paul Flicek, Associate Director of EMBL-EBI Services, Senior Scientist, Group and Team Leader at EMBL-EBI.
2020
embl-announcementslab-matters
Lab MattersPeople & Perspectives Open Targets welcomes new Informatics Science Director
2020
lab-matterspeople-perspectives
Science & Technology Researchers evaluate how the new coronavirus rewires human proteins for its own replication, and identify several antiviral drugs ready for clinical trials
2020
sciencescience-technology
Science & Technology Today we celebrate the 20th anniversary of the first draft of the entire human genome.
2020
sciencescience-technology
Science & Technology DNA damage caused by chemical mutagens is not repaired immediately and can create more genetic diversity in tumours.
2020
sciencescience-technology
Science & Technology EMBL scientists have performed a large-scale analysis of over 4700 SARS-CoV-2 genome sequences. They found that many of the most interesting changes in the SARS-CoV-2 genome that have been reported so far are likely to be technical artefacts, rather than biological mutations.
2020
sciencescience-technology
Lab Matters The European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI) and the Biotechnology and Biological Sciences Research Council (BBSRC) warmly welcome today’s announcement from the UK Government of a £75 million commitment from the Department for Business, Innovation…
2011
lab-matters
Lab Matters Today marks an important step for ELIXIR, Europe’s emerging research infrastructure for life-science information, as five countries plus the European Molecular Biology Laboratory (EMBL) have signed a Memorandum of Understanding to catalyse the implementation and construction of ELIXIR. The…
2011
lab-matters
Lab Matters The Biotechnology and Biological Sciences Research Council (BBSRC) and the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI) welcome news that funding has been earmarked from the UK’s Large Facilities Capital Fund for ELIXIR – the European Life-science…
2011
lab-matters
Science & Technology Red blood cells, the delivery men that take oxygen to cells all around the body, have short lives. To keep enough of them in circulation, the human body produces around 2 million of these cells every second – even more in response to challenges like severe blood loss. In a study published today…
2010
sciencescience-technology
Science & Technology Just like members of an orchestra are active at different times although playing the same piece of music, every cell in our body contains the same genetic sequence but expresses this differently to give rise to cells and tissues with specialised properties. By integrating gene expression data from…
2010
sciencescience-technology
Science & Technology ChEMBLdb, a vast online database of information on the properties and activities of drugs and drug-like small molecules and their targets, launches today with information on over half a million compounds. The data lie at the heart of translating information from the human genome into successful new…
2010
sciencescience-technology
Science & Technology Genes that contain instructions for making proteins make up less than 2% of the human genome. Yet, for unknown reasons, most of our genome is transcribed into RNA. The same is true for many other organisms that are easier to study than humans. Researchers in the groups of Lars Steinmetz at the…
2009
sciencescience-technology
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