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3D

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4 March 2022 A gloved hand holds a slide with visible wells containing Matrigel immersed in culture medium. A magnified close-up shows a mouse embryo developing over the course of 48 hours

A 3D culture model to study embryo growth

A recent study by EMBL researchers proposes a new method to grow early embryos in the laboratory. With a 3D culture set-up, scientists can closely monitor the changes embryos undergo around the time of implantation.

SCIENCE & TECHNOLOGY

2022

sciencescience-technology

4 August 2020 A long string of cells - red in the centre, yellow at the border.

Fish close-up

This group of cells represents an interesting example of organ formation where cells simultaneously move and change their shapes in a highly coordinated manner.

SCIENCE & TECHNOLOGY

2020

picture-of-the-weekscience-technology

4 February 2013

Learning from the linker

Mature cells can be reprogrammed to pluripotency and thus regain the ability to divide and differentiate into specialized cell types. Although these so-called induced pluripotent stem cells (iPS cells) represent a milestone in stem cell research, many of the biochemical processes that underlie…

SCIENCE & TECHNOLOGY

2013

sciencescience-technology

21 July 2011 Model of the inner ring (green) of the nuclear pore, showing its components.

A hot species for cool structures

A fungus that lives at extremely high temperatures could help understand structures within our own cells. Scientists at the European Molecular Biology Laboratory (EMBL) and Heidelberg University, both in Heidelberg, Germany, were the first to sequence and analyse the genome of a heat-loving fungus,…

SCIENCE & TECHNOLOGY

2011

sciencescience-technology

23 June 2009 Lattice maps for immature HIV particles. The 3D computer reconstruction shows the immature Gag lattice of HIV that matures to form the protein shell of the infecious virus. Maps are shown in perspective such that hexamers on the rear surface of the particle appear smaller. The side of the particle toward the viewer lacks ordered Gag. IMAGE: John Briggs/EMBL

New electron microscopy images reveal the assembly of HIV

Scientists at the European Molecular Biology Laboratory (EMBL) and the University Clinic Heidelberg, Germany, have produced a three-dimensional reconstruction of HIV (Human Immunodeficiency Virus), which shows the structure of the immature form of the virus at unprecedented detail. Immature HIV is…

SCIENCE & TECHNOLOGY

2009

sciencescience-technology

22 October 2008

Picture Release

What at the first sight could be pictures of planets or other cosmic structures are actually microscope images of balls (cysts) of human kidney cells. They were taken by Emmanuel Reynaud, in the group of Ernst Stelzer at the European Molecular Biology Laboratory (EMBL), with a widefield microscope.…

SCIENCE & TECHNOLOGY

2008

sciencescience-technology

11 July 2006

Mapping the protein world

In the early days of X-ray crystallography obtaining a three-dimensional model of a protein required wire models, screws, bolts and years of tedious calculations by hand. Today macromolecular models are built by computers – thanks to sophisticated software and in particular a package called…

LAB MATTERSSCIENCE & TECHNOLOGY

2006

lab-mattersscience-technology

31 March 2005

The transparent organism

A novel high-tech microscope will be brought to the marketplace, giving laboratories everywhere fascinating new insights into living organisms. EMBLEM Technology Transfer GmbH (EMBLEM), the commercial entity of the European Molecular Biology Laboratory (EMBL), announced today that it has signed a…

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2005

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