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bacteria

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31 July 2024 Silhouette of gastrointestinal track alongside an illustrator's representation of the carcinogens and antibiotics that seem to be affected by the gut microbiome

Gut microbes implicated in bladder cancer

Science & Technology Study shows that gut bacteria can metabolise carcinogens and cause them to accumulate in distant organs, leading to tumour development.

2024

science-technology

17 October 2023 Pill icons representing different antibiotic classes are seen exerting their effects on a bacterium, whose cell wall, membrane, and protein synthesis machinery (two different classes) can be seen as potential targets. Curved lines connect the pills to each other, representing synergies in drug interactions. More bacteria can be seen in the background.

Fighting antimicrobial resistance with new drug combinations

Science & Technology In an extensive investigation, EMBL researchers have tested over 10,000 drug combinations against some of the leading pathogenic bacteria carrying antimicrobial resistance and causing mortality. 

2023

sciencescience-technology

25 July 2023 Ensembl logo in white circle on blue and green background

Ensembl Bacteria releases new annotation for all its genomes

Ensembl 110 and Ensembl Genomes 57 have introduced in-house prokaryotic gene annotation across genomes available in Ensembl Bacteria.  Since its inception, Ensembl Bacteria has imported user-submitted annotations from the International Nucleotide Sequence Database Collaboration (INSDC) for…

2023

updates-from-data-resources

7 June 2022 Female scientist photographed in a garden

Welcome: Pascale Cossart

Lab MattersPeople & Perspectives Pascale Cossart, one of the world’s foremost authorities on the biology of Listeria, brings four decades of expertise in intracellular bacterial parasitism to EMBL as a visiting scientist.

2022

lab-matterspeople-perspectives

10 November 2021 Graphic representations of different types of bacteria.

Making sense of bacterial DNA data

Science & Technology A vast, curated collection of bacterial genomes is now organised, searchable and open to the community.

2021

sciencescience-technology

22 October 2021 Oblong shape with two holes and coloured dots inside, representing phytoplankton cells and nitrogen-fixing bacteria

Analysis and sorting with flow cytometry

Lab MattersScience & Technology A technology around since the ‘60s, flow cytometry has increasing applications. New leadership at EMBL’s flow cytometry facilities is looking to ease use, expand training, and encourage more collaboration.

2021

lab-mattersscience-technology

13 October 2021 Illustration of a community of bacteria. Pills represent an antibiotic that can be used to treat an infection, and a second drug that could protect many gut bacteria from antibiotics.

Tackling the collateral damage from antibiotics

Science & Technology Researchers from EMBL’s Typas group and collaborators have analysed the effects of 144 antibiotics on the wellbeing of gut microbes. The study improves our understanding of antibiotics’ side effects and suggests a new approach to mitigating the adverse effects of antibiotics therapy on gut…

2021

sciencescience-technology

8 September 2021 Illustration of two halves of a pill, which releases chemical molecules that are taken up by gut bacteria in the vicinity.

Common medications accumulate in gut bacteria

Science & Technology A new collaborative study led by EMBL group leaders Kiran Patil, Nassos Typas, and Peer Bork has found that common medications accumulate in human gut bacteria. This process reduces drug effectiveness and affects the metabolism of common gut microbes, thereby altering the gut microbiome.

2021

sciencescience-technology

17 June 2021 Three researchers surround microscopy equipment in a dark room with red lighting.

Illuminating protein complexes in cells

Lab MattersPeople & Perspectives EMBL group leaders Julia Mahamid, Anna Kreshuk & Jonas Ries awarded Chan Zuckerberg Initiative grant to advance what we see inside cells.

2021

lab-matterspeople-perspectives

19 February 2021 New group leader Gautam Dey looks smiling towards the camera,

Welcome to EMBL: Gautam Dey

Lab MattersPeople & Perspectives Gautam Dey is fascinated by the evolutionary origins of the nucleus, and is looking forward to making the most of EMBL's infrastructure.

2021

lab-matterspeople-perspectives

14 January 2021 An electron microscopy photo shows two bacterial cells surrounded by several white fibrils of the amphibian peptide.

Toadlet peptide transforms into a deadly weapon against bacteria

Science & Technology Researchers at the Technion – Israel Institute of Technology and EMBL Hamburg, in collaboration with scientists in Israel and Spain, have discovered remarkable molecular properties of an antimicrobial peptide from the skin of the Australian toadlet. The discovery could inspire the development of…

2021

sciencescience-technology

29 September 2020 A metal rack holding glass test tubes with yellow and red solutions in them.

Colourful test tubes

Science & Technology To study the effect of commonly used drugs on bacterial envelopes, EMBL scientists applied a biochemical assay using a colour reaction. The deeper the red, the stronger the disruptive effect of the drug.

2020

picture-of-the-weekscience-technology

17 June 2019 A photo of the Hamburg harbour at dusk

EMBL and Tara: Hamburg

EMBL Announcements EMBL Hamburg and Tara raise awareness of the risks of microplastic pollution and global infection

2019

embl-announcementsevents

21 February 2019 Tanmay Bharat and Patrick Baeuerle, winners of the EMBL's 2019 alumni awards

2019 alumni awards

People & Perspectives Scientists honoured for contributions in cancer immunotherapy and structural biology

2019

alumnipeople-perspectives

19 March 2018 Commonly used drugs affect our gut bacteria.

Commonly used drugs affect our gut bacteria

Science & Technology One in four drugs with human targets inhibit the growth of bacteria in the human gut, and may promote antibiotic resistance, EMBL researchers report in Nature

2018

sciencescience-technology

5 December 2012

My microbes

Science & Technology In a nutshell : The gut metagenome is the collection of all the genomes of all the microbes  in the human intestinal tract : it is specific to each human, like a second genetic signature At least in healthy humans, this personal metagenome is stable over time The gut metagenome is…

2012

sciencescience-technology

28 February 2012

Making the most of what you have

Science & Technology The bacterium Mycoplasma pneumoniae, which causes atypical pneumonia, is helping scientists uncover how cells make the most of limited resources. By measuring all the proteins this bacterium produces, scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and…

2012

sciencescience-technology

20 April 2011 Artistic impression of the 3 human gut types.

What’s your gut type?

In the future, when you walk into a doctor’s surgery or hospital, you could be asked not just about your allergies and blood group, but also about your gut type. Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and collaborators in the international MetaHIT…

2011

science

4 March 2010

Bacterial balance that keeps us healthy

The thousands of bacteria, fungi and other microbes that live in our gut are essential contributors to our good health. They break down toxins, manufacture some vitamins and essential amino acids, and form a barrier against invaders. A study published today in Nature shows that, at 3.3 million,…

2010

science

31 January 2010

MicroRNA: a glimpse into the past

The last ancestor we shared with worms, which roamed the seas around 600 million years ago, may already have had a sophisticated brain that released hormones into the blood and was connected to various sensory organs. The evidence comes not from a newly found fossil but from the study of microRNAs…

2010

science

19 January 2010 Image credit: Rachel Melwig & Christine Panagiotidis / EMBL

Membrane-coat proteins: bacteria have them too

Although they are present almost everywhere, on land and sea, a group of related bacteria in the superphylum Planctomycetes-Verrucomicrobia-Chlamydiae, or PVC, have remained in relative obscurity ever since they were first described about a decade ago. Scientists at the European Molecular Biology…

2010

science

2 March 2006

A new tree of life allows a closer look at the origin of species

In 1870 the German scientist Ernst Haeckel mapped the evolutionary relationships of plants and animals in the first ‘tree of life’. Since then scientists have continuously redrawn and expanded the tree adding microorganisms and using modern molecular data, yet, many parts of the tree…

2006

science

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