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bioinformatics

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14 January 2025 EMBL Director General Edith Heard (left) and ELLIS President Bernhard Schölkopf (right) are signing the Memorandum of Understanding.

New strategic partnership for AI in the sciences

Memorandum of Understanding between EMBL and ELLIS will drive AI in European life science research, training, and technology. The strategic partnership will promote interdisciplinary training and develop innovative projects that address pressing challenges in human and planetary health.

CONNECTIONS

2025

connections

9 January 2025

DECIPHER v11.29 released

The v11.29 DECIPHER release is out now. Find out about the new features and improvements.

2025

updates-from-data-resources

17 December 2024

Fuelling discovery together: 2024 user survey learnings

Blog post by Eleni Tzampatzopoulou, EMBL-EBI Impact Manager In summer 2024, EMBL-EBI ran a user survey, inviting our community to let us know how they use the open data resources we jointly manage with our collaborators. With over 2,300 responses from 126 countries, we were delighted by the depth…

2024

announcements

25 November 2024

Sparking a data revolution

The introduction of computational methods in biology opened up an entirely new world of insights and breakthroughs. Over the last several decades, EMBL has been at the forefront of discoveries and innovations that have not only propelled the field forward but also opened up access to bioinformatics…

SCIENCE & TECHNOLOGY

2024

science-technology

7 November 2024

Welcome: Dan Trigg

Tell us a little bit about yourself. I’m a chartered civil engineer and I’ve worked in different capacities in the building and construction space. I worked for a contractor, delivering large infrastructure projects, such as roads, tunnels, bridges all over the UK.  I also worked as a…

2024

perspectives

25 October 2024

DECIPHER v11.28 Released

The v11.28 DECIPHER release is out now. Find out about the new features and improvements.

2024

updates-from-data-resources

23 October 2024

BioChemGraph: Unifying structural and bioactivity data to accelerate drug discovery

In the era of data-driven biology, integrating information from different resources is essential yet often challenging. The BioChemGraph project addresses this challenge by creating infrastructure that consolidates structural, functional, and biochemical annotations for small molecules and their…

2024

updates-from-data-resources

21 October 2024 InterPro logo

InterPro 102.0 released

InterPro version 102.0 and InterProScan 5.70-102.0 are now available. 

2024

updates-from-data-resources

8 October 2024

New MGnify Proteins web resources launched

EMBL-EBI’s microbiome data resource MGnify produces a valuable trove of protein sequence data through its ongoing analysis of microbiome derived data. Two new MGnify Proteins web resources make this dataset easily accessible and searchable, both for large queries across the entire database…

2024

updates-from-data-resources

24 September 2024 Single Cell Expression Atlas logo on green background

Single Cell Expression Atlas 21 released

New datasets The release has 381 single-cell RNA-Seq experiments, consisting of more than 13.5 million cells from 21 different species to explore in the Single Cell Expression Atlas (SCEA). The resource now includes an entirely new class of data – externally analysed data, marked with an…

2024

updates-from-data-resources

23 August 2024

Welcome: David Ocaña

EMBL-EBI’s new Head of Applications will use his expertise in cloud infrastructure and security to support the institute’s open data resources.

PEOPLE & PERSPECTIVES

2024

people-perspectivesperspectives

25 July 2024

DECIPHER v11.27 release

The v11.27 DECIPHER release is out now. Find out about the new features and improvements.

2024

updates-from-data-resources

21 June 2024

Welcome: Mallory Freeberg

The new Team Leader for Human Genomics at EMBL-EBI shares how curiosity and maths shaped her career and what it takes to be a community builder.

PEOPLE & PERSPECTIVES

2024

people-perspectivesperspectives

28 May 2024 DECIPHER logo

DECIPHER v11.26 release

The latest DECIPHER release includes AlphaMissense scores, links to the Open Targets Platform and more.

2024

updates-from-data-resources

17 May 2024 Expression Atlas logo

Expression Atlas 40 released

The latest Expression Atlas 40 release is now live, containing new RNA-seq datasets, including a featured experiment resulting from a collaboration with Genotype Tissue Expression (GTEx) project as well as new proteomics data derived from our collaboration with PRIDE. In total, this release…

2024

updates-from-data-resources

13 May 2024 Ensembl logo in white circle on blue and green background

Ensembl 112 has been released

Ensembl 112 and the corresponding release of Ensembl Genomes 59 has released. This includes exciting new fish species, many more drosophila species and new VEP updates.

2024

updates-from-data-resources

8 April 2024 Artist’s stylised, semi-abstract representation of artificial intelligence

When AI meets biology

A recent EMBO | EMBL conference provided a forum for researchers to share how AI is making a difference in biology and bioinformatics.

SCIENCE & TECHNOLOGY

2024

science-technology

2 April 2024

DECIPHER v11.25 released

The latest DECIPHER update, version 11.25, introduces new key features including the integration of functional data from multiplexed assays of variant effect (MAVEs) and much more.

2024

updates-from-data-resources

27 March 2024

Using Data Hubs to analyse SARS-CoV-2 and other pathogen sequences

The SARS-CoV-2 Data Hubs are a set of tools coupled with infrastructure that support four components: the submission, analysis, presentation and visualisation of SARS-CoV-2 raw read data, and its resulting analyses. What makes Data Hubs attractive is a unique set of features: A new publication in…

2024

updates-from-data-resources

8 March 2024 MGnify logo with text underneath which reads release

MGnify Genomes mouse gut catalogue v1.0 released

The MGnify data resource for microbiome data has launched the latest MGnify Genomes catalogue comprising 112,951 genomes derived from mouse gut datasets, represented by 2,847 species-level cluster representative genomes. This catalogue was generated as part of our work with the MRC funded…

2024

updates-from-data-resources

28 February 2024 DECIPHER logo

DECIPHER v11.24 Released

Version 11.24 of DECIPHER introduces a new ACMG/AMP pathogenicity interface for sequence variant predictions, displays ClinGen Variant Curation Expert Panel recommendations on gene pages, and updates ACMG secondary finding information to v3.2.

2024

updates-from-data-resources

29 January 2024 InterPro logo

InterPro 98.0 released

InterPro version 98.0 and InterProScan 5.66-98.0 are now available. InterPro now features hundreds of new methods integrated from partner databases, and InterProScan draws on over 40000 entries. InterPro version 98.0 New features include: InterPro 98.0 covers 81.7% of UniProt Knowledgebase release…

2024

updates-from-data-resources

12 January 2024 Ensembl logo in white circle on blue and green background

Ensembl 111 has been released

The Ensembl 111 features a range of new Ensembl VEP plugins and updated agricultural, fish, plant and metazoa species.

2024

updates-from-data-resources

14 November 2023 InterPro logo

InterPro 97.0 released

InterPro version 97.0 and InterProScan 5.64-97.0 are now available. InterPro now features hundreds of new methods integrated from partner databases, and InterProScan draws on over 40000 entries.

2023

updates-from-data-resources

26 September 2023 InterPro logo

InterPro 96.0 released

InterPro version 96.0 and InterProScan 5.64-96.0 are now available.

2023

updates-from-data-resources

21 September 2023

Understanding the mechanisms of enzyme catalysis

Enzymes constitute a large fraction of genomes – 20% in humans – which makes them a very important part of life. Despite decades of studies and a rich literature dedicated to understanding the reaction mechanisms of enzymes, the rules of enzyme catalysis are still not fully clear. A new…

SCIENCE & TECHNOLOGY

2023

science-technologytechnology-and-innovation

25 July 2023 Ensembl logo in white circle on blue and green background

Ensembl Bacteria releases new annotation for all its genomes

Ensembl 110 and Ensembl Genomes 57 have introduced in-house prokaryotic gene annotation across genomes available in Ensembl Bacteria.  Since its inception, Ensembl Bacteria has imported user-submitted annotations from the International Nucleotide Sequence Database Collaboration (INSDC) for…

2023

updates-from-data-resources

17 July 2023 Ensembl logo in white circle on blue and green background

Ensembl 110 has been released

Ensembl 100 release brings exciting updates, such as the addition of regulation data to 5 animal genomes studied extensively in agriculture.

2023

updates-from-data-resources

7 July 2023 InterPro logo

InterPro 95.0 released

InterPro version 95.0 and InterProScan 5.63-95.0 are now available! InterPro now features hundreds of new methods integrated from partner databases, and InterProScan draws on over 39000 entries. InterPro version 95.0 – new features include: InterPro 95.0 covers 81.7% of UniProt Knowledgebase…

2023

updates-from-data-resources

3 July 2023 In the foreground: an intrinsically disordered protein, which has a form of a tangled, unstructured string. In the background: a set of parallel curved lines.

Bringing research on disordered proteins to order

A third of all known proteins are either completely or partially unstructured. EMBL scientists contributed to a new set of guidelines – Minimum Information About a Disorder Experiment (MIADE) – that will help researchers share data on unstructured proteins in a more useful way and will enable…

SCIENCE & TECHNOLOGY

2023

sciencescience-technology

16 May 2023

Managing a bioinformatics core facility

BioImage Archive Team Leader Matthew Hartley shares his experience and tips for people interested in managing a bioinformatics core facility.

2023

technology-and-innovation

18 April 2023 Decorative image showing WormBase ParaSite logo

WormBase ParaSite 18 released

WormBase ParaSite release 18 adds largest number of new genomes and annotations since launch, as well as full integration with AlphaFold.

SCIENCE & TECHNOLOGY

2023

science-technologyupdates-from-data-resources

29 March 2023 Photographs of two male scientists in circular insets against a decorative background

EMBL Alumni Awards Announced for 2023

Two former EMBL scientists have been recognised for their outstanding contributions to the fields of science communication and multiple sequence alignment research, respectively.

2023

alumni

7 March 2023 InterPro logo

New releases: InterPro 93.0 and InterProScan 5.61-93.0

InterPro now features hundreds of new methods integrated from partner databases, and InterProScan draws on over 38,000 entries. InterPro version 93.0 InterPro 93.0 integrates 300 new methods from the CDD (261), PANTHER (12), PROSITE profiles (17), SMART (9), TIGRFAMs (1) databases, and covers 81.7%…

2023

updates-from-data-resources

23 February 2023 Decorative image

New Job Dispatcher website launched

EMBL-EBI’s Software Development and Operations team is delighted to announce the launch of a brand-new Job Dispatcher website, currently in development.  The updated website provides a landing page for the Job Dispatcher services, making it easier for users to find and navigate services…

2023

updates-from-data-resources

8 February 2023 Ensembl logo in white circle on blue and green background

Ensembl 109 has been released

Latest Ensembl and Ensembl Genomes releases bring updates to donkey and horse assemblies, and lots of new plants and metazoa.

2023

updates-from-data-resources

4 January 2023 InterPro logo

New releases: InterPro 92.0 and InterProScan 5.60-92.0

InterPro version 92.0 and InterProScan 5.60-92.0 are now available. InterPro now features hundreds of new methods integrated from partner databases, and InterProScan draws on over 38000 entries.

2023

updates-from-data-resources

20 December 2022

First linked dataset on Pathogens Portal

The first  cohort study linking data across categories was recently added on the Pathogens Portal Cohort Browser and is also accessible from the BioSamples browser. This pilot study comes from Erasmus Medical Centre through the ReCoDID project, one of the COVID-19 Data Platform supporting…

2022

updates-from-data-resources

11 November 2022 Photos of four panel discussion speakers

Open science for climate justice

Our experts discuss the importance of open science for food security and preserving global biodiversity.

2022

perspectivesscience

2 November 2022 Fluorescent microscopy image of skeletal muscle with biological data imagery

AI4LIFE: AI models for bioimaging

Researchers across EMBL are helping to make artificial intelligence (AI) models for bioimaging analysis interoperable and openly available to the scientific community.

2022

announcementsscience

21 October 2022 Ensembl logo in white circle on blue and green background

Ensembl 108 has been released

We are pleased to announce the release of Ensembl 108, and the corresponding release of Ensembl Genomes 55 featuring changes in the human default tracks, new genomes in Ensembl Plants and Ensembl Metazoa, and the addition of mitochondrial annotation for Tasmanian devil. Genome assemblies and…

2022

updates-from-data-resources

9 August 2022 InterPro logo

New releases: InterPro 90.0 and InterProScan 5.57-90.0

InterPro version 90.0 and InterProScan 5.57-90.0 are now available. InterPro now features hundreds of new methods integrated from partner databases, and InterProScan draws on over 40000 entries

2022

updates-from-data-resources

18 July 2022 Large, elongated purple molecule has an on/off switch on it pointed to on.

The retron switch

EMBL researchers now understand the function of an elusive small DNA in bacteria and have developed a tool that can be used to better understand what might ‘switch on’ bacterial immune defences.

SCIENCE & TECHNOLOGY

2022

sciencescience-technology

9 June 2022 ArrayExpress logo; a red A and green E in a circle with the word ArrayExpress

ArrayExpress interface to close

On 30 September 2022 the ArrayExpress interface will close. All datasets have now been migrated from ArrayExpress into the BioStudies ArrayExpress collection

2022

updates-from-data-resources

21 April 2022 Portrait of Guy Cochrane, Team Leader at EMBL-EBI's European Nucleotide Archive. Credit: Jeff Dowling/EMBL-EBI.

Guy Cochrane appointed Executive Director of Global Biodata Coalition

The GBC is a coalition of life sciences and biomedical research funders that aims to optimise the funding and management of biodata resources worldwide. The organisation has two priority aims: to better coordinate and share approaches for efficient management and growth of the biodata…

2022

announcements

24 February 2022 Expression Atlas database logo - A magnifying glass highlighting a yellow section on a blue background

New Expression Atlas release in collaboration with PRIDE

New Expression Atlas release features differential-proteomics and baseline-proteomics experiments in collaboration with the PRIDE team at EMBL-EBI. This also includes new baseline DIA proteomics experiments as well as new differential proteomics datasets.  To improve reproducibility,…

2022

updates-from-data-resources

21 May 2021 Image of a mosquito on a clear surface

EMBL scientists support malaria research

EMBL scientists support research on malaria by providing freely available data resources and using innovative experimental approaches. Our Course and Conference Office facilitates the exchange of knowledge in the field by hosting the annual BioMalPar conference.

SCIENCE & TECHNOLOGY

2021

sciencescience-technology

15 October 2020 Four blue circular objects are surrounded with green structures, and the central blue circle with pink structures. The blue circles are human cell nuclei, and pink and green structures are proteins.

Repurposing drugs for a pan-coronavirus treatment

Scientists from the Beltrao Group at EMBL-EBI and collaborators identified drug targets common to SARS-CoV-2, SARS-CoV-1, and MERS-CoV, three pathogenic coronaviruses. They also found potential drugs that could be repurposed as COVID-19 treatments, and against emerging coronavirus strains in the…

SCIENCE & TECHNOLOGY

2020

sciencescience-technology

10 September 2020 Two researchers at EMBL's state-of-the-art Electron Microscopy Core Facility (EMCF). A female scientist is using a binocular microscope, a male scientist is standing next to her.

Level up!

ARISE fellowships to offer first-ever comprehensive training for bioscience infrastructure operations

LAB MATTERS

2020

lab-matters

3 August 2020 A woman with glasses holds a book. The book cover says "Gene naming rules". Thought bubbles float around her head and display gene symbols like BRCA1.

Bagpipe and Pokemon, or how not to name a human gene

The human genome harbours about 19 000 protein-coding genes, many of which still have no known function. As scientists unveil the secrets of our DNA, they come across novel genes that they need to refer to using a unique name. The Human Genome Organisation’s Gene Nomenclature Committee (HGNC) at…

SCIENCE & TECHNOLOGY

2020

sciencescience-technology

20 July 2020 A magnifying glass hovers over the human gut, revealing its biodiversity.

Unparalleled inventory of the human gut ecosystem

An international team of scientists has collated all known bacterial genomes from the human gut microbiome into a single large database. Their work will allow researchers to explore the links between bacterial genes and proteins, and their effects on human health.

SCIENCE & TECHNOLOGY

2020

sciencescience-technology

13 May 2020 Close-up photograph of servers at EMBL Heidelberg's data centre.

Understanding the role of our genes in SARS-CoV-2 infections

EMBL scientists will contribute to the new German COVID-19 OMICS Initiative to study the biological mechanisms contributing to coronavirus infections. EMBL group leaders Jan Korbel and Oliver Stegle, who is also affiliated with the DKFZ Heidelberg, will coordinate the set-up of IT infrastructures…

SCIENCE & TECHNOLOGY

2020

sciencescience-technology

24 April 2020 Collage of images representing wet and dry lab research and healthcare

Why share data during a pandemic?

In March 2020, planes were grounded, streets went quiet, and our lives changed forever. But while the world came to a halt, many scientists were ramping up their efforts to understand the new virus.

SCIENCE & TECHNOLOGY

2020

sciencescience-technology

5 February 2020

Analysis of human genomes in the cloud

Scientists from EMBL present a tool for large-scale analysis of genomic data with cloud computing. Main advantages of the new tool, called Butler, are continuous system monitoring and its ability to self-heal in case of failure, allowing for 43% more efficient data processing than previous…

SCIENCE & TECHNOLOGY

2020

sciencescience-technology

4 August 2016 45 pupils from Saarland, Germany visit EMBL-EBI

Just try!

German students visit EMBL-EBI on a tour to explore a new culture and different career paths

LAB MATTERS

2016

lab-matters

2 October 2015 The 1000 Genomes Project: a timeline

A lasting legacy

1000 Genomes Project pushed technologies and knowledge forward to understand what is 'normal' human genetic variation

SCIENCE & TECHNOLOGY

2015

sciencescience-technology

27 May 2015

ELIXIR accelerates

ELIXIR receives major Horizon 2020 funding to ‘EXCELERATE' activities over the next four years.

LAB MATTERS

2015

lab-matters

20 January 2015 COMPARE project

Beyond COMPARE

New project aims to speed up detection and response to disease outbreaks using genome technology.

LAB MATTERS

2015

lab-matters

21 October 2014 Map of EMBL-EBI users

Job dispatched

How does EMBL-EBI run millions of jobs for its users while moving its two large data centres?

LAB MATTERS

2014

lab-matters

8 October 2014

EU Codefest

Pooling programming and problem-solving expertise in bioinformatics at EMBL-EBI.

2014

events

1 July 2014 Vasily Sysoev

Back to school

School ambassadors show next generation that scientists are more ‘role model’ than ‘mad professor’

LAB MATTERS

2014

lab-matters

4 March 2010

Bacterial balance that keeps us healthy

The thousands of bacteria, fungi and other microbes that live in our gut are essential contributors to our good health. They break down toxins, manufacture some vitamins and essential amino acids, and form a barrier against invaders. A study published today in Nature shows that, at 3.3 million,…

SCIENCE & TECHNOLOGY

2010

sciencescience-technology

19 January 2010 Image credit: Rachel Melwig & Christine Panagiotidis / EMBL

Membrane-coat proteins: bacteria have them too

Although they are present almost everywhere, on land and sea, a group of related bacteria in the superphylum Planctomycetes-Verrucomicrobia-Chlamydiae, or PVC, have remained in relative obscurity ever since they were first described about a decade ago. Scientists at the European Molecular Biology…

SCIENCE & TECHNOLOGY

2010

sciencescience-technology

22 January 2008

International consortium announces the 1000 Genomes Project

Drawing on the expertise of multi-disciplinary research teams, the map developed by the 1000 Genomes Project will provide a view of biomedically relevant DNA variations at a resolution unmatched by current resources. The European Bioinformatics Institute (EBI), working with long-term collaborator…

LAB MATTERS

2008

lab-matters

23 October 2007

The East Wing and a new dawn for the EMBL-EBI

The European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI) officially opens its new East Wing today with a reception for prominent guests. The East Wing will be jointly opened by Ian Pearson, Minister of State for Science and Innovation, UK, and Robert-Jan Smits,…

LAB MATTERS

2007

lab-matters

27 November 2006

CiteXplore

Today the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI) launches CiteXplore, a new freely accessible literature resource service. Biological researchers require two crucial sources of information: scientific literature published in peerreviewed…

LAB MATTERSSCIENCE & TECHNOLOGY

2006

lab-mattersscience-technology

28 February 2005

Double recognition of EBI scientists by the ISCB

The International Society for Computational Biology has named two scientists from the European Bioinformatics Institute as the winners of its awards for 2005. Janet Thornton wins the Senior Scientist Accomplishment Award while the Overton Prize goes to Ewan Birney. Thomas Lengauer, the ISCB’s…

EMBL ANNOUNCEMENTS

2005

embl-announcements

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