Edit

Tag:

bork

Showing results out of

Year

10 December 2024 Portrait pictures of two men inserted on a green background.

Portrait pictures of two men inserted on a green background.

EMBL announces interim leadership

EMBL announces that Peer Bork and Ewan Birney will lead the organisation after the departure of Director General Edith Heard in summer 2025.

EMBL ANNOUNCEMENTS

2024

embl-announcements

13 November 2024 Illustration showing a human gut floating over a scale resting on a microchip labelled ‘AI’. The two sides of the scale show a varying number of bacteria, shown against a backdrop of 0s and 1s.

Illustration showing a human gut floating over a scale resting on a microchip labelled ‘AI’. The two sides of the scale show a varying number of bacteria, shown against a backdrop of 0s and 1s.

Microbial load can influence disease associations

Scientists have developed a new machine-learning model to predict microbial load — the density of microbes in our guts — and used it to demonstrate how microbial load plays an important role in disease-microbiome associations.

SCIENCE & TECHNOLOGY

2024

science-technology

24 September 2024 Illustration showing several drugs being broken down when reaching a community of gut bacteria. This community has different types of bacteria.

Illustration showing several drugs being broken down when reaching a community of gut bacteria. This community has different types of bacteria.

Better together: gut microbiome communities’ resilience to drugs

EMBL Heidelberg researchers compared the effect of drugs on isolated bacteria versus those growing in communities. This is the first study showing that bacteria are more resilient when in community due to cross-protection strategies. This could help researchers design more efficient therapies.

SCIENCE & TECHNOLOGY

2024

science-technology

4 April 2023 A mobile lab on a road, with the TREC logo on the side.

TREC is underway!

EMBL’s planetary biology flagship TREC expedition has officially started. The new project applies EMBL's expertise and technologies in molecular and cellular biology to current environmental challenges, and connects with a wide range of research disciplines.

EMBL ANNOUNCEMENTS

2023

embl-announcementseventsscience

8 March 2023

TREC: A two-year mission to study human impact on Europe’s seas and coastal regions

EMBL is leading the TREC project: the first pan-European and cross-disciplinary effort to examine life in its natural context.

EMBL ANNOUNCEMENTS LAB MATTERS

2023

embl-announcementslab-matters

28 September 2022 3D structures of ribosomes are shown floating in a cellular space. A zoomed in portion shows an antibiotic molecule nested in a binding site on a ribosome.

3D structures of ribosomes are shown floating in a cellular space. A zoomed in portion shows an antibiotic molecule nested in a binding site on a ribosome.

Seeing antibiotics in action inside a pathogenic bacterium

New research by EMBL scientists shows at atomic detail how antibiotics affect the process of protein production inside bacteria.

SCIENCE & TECHNOLOGY

2022

sciencescience-technology

15 September 2022 The foreground shows two yellow pipes representing the human gastrointestinal tract coming together, representing the confluence of donor and recipient gut ecosystems. Bacteria can be seen as green shapes inside the pipes and various kinds of interactions between them are shown symbolically as a mixing of colours.

The foreground shows two yellow pipes representing the human gastrointestinal tract coming together, representing the confluence of donor and recipient gut ecosystems. Bacteria can be seen as green shapes inside the pipes and various kinds of interactions between them are shown symbolically as a mixing of colours.

When microbiomes collide

EMBL researchers used data from over 300 human faecal microbiota transplants to gain an ecological understanding of what happens when two gut microbiomes clash.

SCIENCE & TECHNOLOGY

2022

sciencescience-technology

15 December 2021 An outline of Earth, covered with depictions of bacteria. The image of Earth is within a the frame of a computer window. There is an “Upload file” button on the bottom left, and a mouse cursor on the right.

An outline of Earth, covered with depictions of bacteria. The image of Earth is within a the frame of a computer window. There is an “Upload file” button on the bottom left, and a mouse cursor on the right.

Connecting the dots between bacterial genes around the world

Bork Group at EMBL Heidelberg analysed a new global gene database to study how genes emerge and spread across various habitats on our planet. In the future, the group will expand the database and use it for studying microbial gene evolution and dispersal at a finer-grained scale.

SCIENCE & TECHNOLOGY

2021

sciencescience-technology

8 December 2021 An illustration of the human gut, with coloured shapes representing bacteria. Three different drugs and drug combinations are shown affecting the bacteria, represented by changes in colour

An illustration of the human gut, with coloured shapes representing bacteria. Three different drugs and drug combinations are shown affecting the bacteria, represented by changes in colour

The impact of drugs on gut microbes is greater than we thought

Researchers studying a massive cohort of European patients have found that commonly prescribed drugs for cardiometabolic disorders can have long-term effects on the gut microbiome. Such effects can complicate the understanding of how disease affects the microbiome and must be taken into…

SCIENCE & TECHNOLOGY

2021

sciencescience-technology

8 September 2021 Illustration of two halves of a pill, which releases chemical molecules that are taken up by gut bacteria in the vicinity.

Illustration of two halves of a pill, which releases chemical molecules that are taken up by gut bacteria in the vicinity.

Common medications accumulate in gut bacteria

A new collaborative study led by EMBL group leaders Kiran Patil, Nassos Typas, and Peer Bork has found that common medications accumulate in human gut bacteria. This process reduces drug effectiveness and affects the metabolism of common gut microbes, thereby altering the gut microbiome.

SCIENCE & TECHNOLOGY

2021

sciencescience-technology

30 July 2021 Photo of Peer Bork, Director of EMBL Heidelberg (Scientific Activities), winner of Novozymes Prize 2021

Photo of Peer Bork, Director of EMBL Heidelberg (Scientific Activities), winner of Novozymes Prize 2021

Peer Bork honoured with Novozymes Prize and ISCB Senior Scientist Award

Distinctions recognise Peer’s development and sharing of bioinformatics tools as well as his significant contributions to bioinformatics research, education, and services.

LAB MATTERS PEOPLE & PERSPECTIVES

2021

lab-matterspeople-perspectives

16 June 2021 Microscopy images of bacteria against a backdrop of a crowd of humans.

Microscopy images of bacteria against a backdrop of a crowd of humans.

How our gut microbiome changes over time

Researchers investigate how external factors can influence the persistence of microbe species in the human gut

SCIENCE & TECHNOLOGY

2021

sciencescience-technology

3 June 2021 Illustration of a rocky coastline with sailing boat, mountains, underwater organisms, bridge and factory in the background.

Illustration of a rocky coastline with sailing boat, mountains, underwater organisms, bridge and factory in the background.

Living laboratories

Under the innovative Planetary Biology research theme, EMBL scientists aim to understand life in the context of its environment.

SCIENCE & TECHNOLOGY

2021

sciencescience-technology

25 April 2019 The proteotype of an individual is substantially affected by both its sex and its diet.

The proteotype of an individual is substantially affected by both its sex and its diet.

Sex and diet affect proteotype

EMBL scientists have discovered that the proteome is substantially affected by both sex and diet

SCIENCE & TECHNOLOGY

2019

sciencescience-technology

26 February 2019 Mouth and gut are highlighted as locations for genetic material compared by scientists

Mouth and gut are highlighted as locations for genetic material compared by scientists

Many gut microbes may originate in the mouth

Many microbes traverse the oral-gut barrier

SCIENCE & TECHNOLOGY

2019

sciencescience-technology

1 August 2018 Global warfare between bacteria and fungi in soil. IMAGE: Hildebrand/Krolik in collaboration with Campbell Medical Illustration/EMBL

Global warfare between bacteria and fungi in soil. IMAGE: Hildebrand/Krolik in collaboration with Campbell Medical Illustration/EMBL

Understanding soil through its microbiome

First global survey of soil genomics reveals a war between fungi and bacteria

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

11 July 2018 IMAGE: Aleksandra Krolik, EMBL

IMAGE: Aleksandra Krolik, EMBL

Maternal bacteria persistent in newborns

Scientists show how bacteria and other microorganisms are passed on from mother to child

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

19 April 2018

Dog microbiome closer to humans' than expected

Dog microbiome closer to humans’ than expected

Dog and human gut microbiomes have more similar genes and responses to diet than previously thought

PEOPLE & PERSPECTIVES

2018

people-perspectivesscience

19 March 2018

Commonly used drugs affect our gut bacteria.

Commonly used drugs affect our gut bacteria

One in four drugs with human targets inhibit the growth of bacteria in the human gut, and may promote antibiotic resistance, EMBL researchers report in Nature

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

19 March 2018

Molecular cuisine for gut bacteria. IMAGE: Aleksandra Krolik / EMBL

Molecular cuisine for gut bacteria

EMBL scientists show how to grow a wide range of gut bacteria in the lab

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

20 October 2016

Diving into Autumn

Participants learn about EMBL’s ocean biodiversity research at the Fall Gala

CONNECTIONS

2016

connectionsevents

29 August 2016

Awards & Honours

EMBL scientists regularly receive prestigious awards – meet the latest honourees.

EMBL ANNOUNCEMENTS LAB MATTERS

2016

embl-announcementslab-matters

24 June 2016

Bork lab peers gather

27 former Bork lab members joined Peer for a full-day get-together this summer

LAB MATTERS

2016

alumnilab-matters

28 April 2016 Illustration linking the guts of donor and recipient. IMAGE: Andrea Levy/The Plain Dealer

Illustration linking the guts of donor and recipient. IMAGE: Andrea Levy/The Plain Dealer

Poo transplants better understood

Stool transplants: finding the right match important, EMBL study shows

SCIENCE & TECHNOLOGY

2016

sciencescience-technology

20 August 2015

First, find your membrane

Collaboration between scientists reveals collaboration between lipids.

SCIENCE & TECHNOLOGY

2015

sciencescience-technology

21 July 2011 Model of the inner ring (green) of the nuclear pore, showing its components.

Model of the inner ring (green) of the nuclear pore, showing its components.

A hot species for cool structures

A fungus that lives at extremely high temperatures could help understand structures within our own cells. Scientists at the European Molecular Biology Laboratory (EMBL) and Heidelberg University, both in Heidelberg, Germany, were the first to sequence and analyse the genome of a heat-loving fungus,…

SCIENCE & TECHNOLOGY

2011

sciencescience-technology

20 April 2011 Artistic impression of the 3 human gut types.

Artistic impression of the 3 human gut types.

What’s your gut type?

In the future, when you walk into a doctor’s surgery or hospital, you could be asked not just about your allergies and blood group, but also about your gut type. Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and collaborators in the international MetaHIT…

SCIENCE & TECHNOLOGY

2011

sciencescience-technology

4 March 2010

Bacterial balance that keeps us healthy

The thousands of bacteria, fungi and other microbes that live in our gut are essential contributors to our good health. They break down toxins, manufacture some vitamins and essential amino acids, and form a barrier against invaders. A study published today in Nature shows that, at 3.3 million,…

SCIENCE & TECHNOLOGY

2010

sciencescience-technology

31 January 2010

MicroRNA: a glimpse into the past

The last ancestor we shared with worms, which roamed the seas around 600 million years ago, may already have had a sophisticated brain that released hormones into the blood and was connected to various sensory organs. The evidence comes not from a newly found fossil but from the study of microRNAs…

SCIENCE & TECHNOLOGY

2010

sciencescience-technology

26 November 2009

This image represents the integration of genomic, metabolic, proteomic, structural and cellular information about Mycoplasma pneumoniae in this project: one layer of an Electron Tomography scan of a bottle-shaped M. pneumoniae cell (grey) is overlaid with a schematic representation of this bacterium’s metabolism, where blue indicates interactions between proteins encoded in genes from the same functional unit. Apart from these expected interactions, the scientists found that, surprisingly, many proteins are multifunctional. For instance, there were various unexpected physical interactions (yellow lines) between proteins and the subunits that form the ribosome, which is depicted as an Electron microscopy image (yellow). Image credit: Takuji Yamada / EMBL

First-ever blueprint of a minimal cell is more complex than expected

What are the bare essentials of life, the indispensable ingredients required to produce a cell that can survive on its own? Can we describe the molecular anatomy of a cell, and understand how an entire organism functions as a system? These are just some of the questions that scientists in a…

SCIENCE & TECHNOLOGY

2009

sciencescience-technology

3 February 2005

Biology in four dimensions

Most things that happen in the cell are the work of ‘molecular machines’ – complexes of proteins that carry out important cellular functions. Until now, scientists didn’t have a clear idea of when proteins form these machines – are these complexes pre-fabricated or put…

SCIENCE & TECHNOLOGY

2005

sciencescience-technology

No results found

Edit