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brain

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10 February 2025 A schematic of a mouse showing the gut and the brain linked by a diffuse stream of light. Brain proteins with glycosyl groups shown in a different colour are seen in the periphery, and an inset shows bacteria in the gut.

A schematic of a mouse showing the gut and the brain linked by a diffuse stream of light. Brain proteins with glycosyl groups shown in a different colour are seen in the periphery, and an inset shows bacteria in the gut.

Bacteria, brains, and sugar: scientists uncover new connections

Scientists have discovered that gut bacteria can alter molecular signatures in the brain, using a brand new method to study how carbohydrates modify proteins.

SCIENCE & TECHNOLOGY

2025

science-technology

10 September 2024 A brain section is seen in the background, from which a 'highway'emerges, with lit up neurons spaced like cars on the highway.

A brain section is seen in the background, from which a 'highway'emerges, with lit up neurons spaced like cars on the highway.

Follow the cellular road

An AI-enhanced advanced microscopy approach offers promise in better understanding glioblastomas, one of the deadliest brain cancers.

SCIENCE & TECHNOLOGY

2024

science-technology

27 August 2024 In the foreground is a photoacoustic dye from the red end of the visible spectrum that is ‘turned on’. It produces an ultrasound emission that can be detected and measured. A dye that is ‘turned off’ is shown in the left background.

In the foreground is a photoacoustic dye from the red end of the visible spectrum that is ‘turned on’. It produces an ultrasound emission that can be detected and measured. A dye that is ‘turned off’ is shown in the left background.

Seeing into the depths

EMBL scientists applied molecular engineering to build photoacoustic probes to label and visualise neurons deep within brain tissue.

SCIENCE & TECHNOLOGY

2024

science-technology

16 November 2023

New evidence on retinal function

A new study from the Asari group at EMBL Rome shows a different retinal function in awake mice compared to isolated retinal samples. These new insights could help to develop prosthetic devices that can act as a retina in the future.

SCIENCE & TECHNOLOGY

2023

sciencescience-technology

30 March 2023 Profile picture of Cornelius Gross, interim head of EMBL Rome

ERC Advanced Grant awarded to EMBL Rome researcher

Interim head of EMBL Rome Cornelius Gross has been awarded an Advanced grant from the European Research Council (ERC) for his project TERRITORY, aimed at investigating the neural basis of territorial aggression and fear.

EMBL ANNOUNCEMENTS LAB MATTERS

2023

embl-announcementslab-matters

25 October 2022 Cells found in the brain

Cells found in the brain

Mapping the human brain: a global collaboration

NIH BRAIN Initiative to fund brain atlases, network coordination, and knowledge sharing to explore brain function research.

2022

announcementsscience

8 June 2022 Two female scientists shown against a green background

Two female scientists shown against a green background

2022 EMBL Alumni Awards Winners announced

Two former EMBL staff members have been recognised for their outstanding contributions to research in the fields of brain evolution and cancer.

EMBL ANNOUNCEMENTS

2022

alumniembl-announcements

30 September 2021

New microscopy technique makes deep in vivo brain imaging possible

Scientists in EMBL’s Prevedel Group have developed a pioneering microscopy technique that allows researchers to observe cells hidden within opaque tissues, such as live neurons embedded deep in the brain.

SCIENCE & TECHNOLOGY

2021

sciencescience-technology

2 December 2020 Curly-shaped trypanosomes, grey with bright specks of green fluorescent protein, against a grey background.

Curly-shaped trypanosomes, grey with bright specks of green fluorescent protein, against a grey background.

Tackling tropical diseases

Members of the EMBL community are working to improve our understanding of the parasites that cause malaria and sleeping sickness

SCIENCE & TECHNOLOGY

2020

sciencescience-technology

19 November 2019

Formation of a brain

The brain is the most complex organ in the human body. Yet despite it being the organ that makes us conscious beings – and despite the fact that researchers have been studying it for generations – it’s still a constant source of surprise. To help lift the veil on some of its mystery, Lina…

SCIENCE & TECHNOLOGY

2019

picture-of-the-weekscience-technology

26 March 2018 Multiple synapse heads send out filopodia (green) converging on one microglia (red), as seen by focused ion beam scanning electron microscopy (FIBSEM).

Multiple synapse heads send out filopodia (green) converging on one microglia (red), as seen by focused ion beam scanning electron microscopy (FIBSEM).

Captured: microglia nibbling on brain synapses

For the first time, EMBL Rome researchers have captured microglia nibbling on brain synapses on film.

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

10 November 2013

What are you scared of?

What do bullies and sex have in common? Based on work by scientists at the European Molecular Biology Laboratory (EMBL) in Monterotondo, Italy, it seems that the same part of the brain reacts to both. In a study published today in Nature Neuroscience, the researchers found that – at least in…

SCIENCE & TECHNOLOGY

2013

sciencescience-technology

24 May 2012 Microglial cells

Microglial cells

Locating ground zero

Like emergency workers rushing to a disaster scene, cells called microglia speed to places where the brain has been injured, to contain the damage by ‘eating up’ any cellular debris and dead or dying neurons. Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany,…

SCIENCE & TECHNOLOGY

2012

sciencescience-technology

19 January 2012 Artist's impression of a chromosome exploding

Artist's impression of a chromosome exploding

Rigged to explode?

An inherited mutation in a gene known as the guardian of the genome is likely the link between exploding chromosomes and some particularly aggressive types of cancer, scientists at the European Molecular Biology Laboratory (EMBL), the German Cancer Research Centre (DKFZ) and the University…

SCIENCE & TECHNOLOGY

2012

sciencescience-technology

21 July 2011 Microglia (green) in a mouse brain. The nuclei of all cells in the brain are labelled blue. Credit: EMBL/ R.Paolicelli

Microglia (green) in a mouse brain. The nuclei of all cells in the brain are labelled blue. Credit: EMBL/ R.Paolicelli

Gardening in the brain

Gardeners know that some trees require regular pruning: some of their branches have to be cut so that others can grow stronger. The same is true of the developing brain: cells called microglia prune the connections between neurons, shaping how the brain is wired, scientists at the European…

SCIENCE & TECHNOLOGY

2011

sciencescience-technology

2 September 2010 A virtual Platynereis brain (left), created by averaging microscopy images of the brains of 36 different individuals, onto which scientists mapped gene activity (right). Perspective shows the brain as viewed from inside a Platynereis larvae, at 48 hours' old. Image credits: EMBL/R. Tomer

A virtual Platynereis brain (left), created by averaging microscopy images of the brains of 36 different individuals, onto which scientists mapped gene activity (right). Perspective shows the brain as viewed from inside a Platynereis larvae, at 48 hours' old. Image credits: EMBL/R. Tomer

Brainy worms: Evolution of the cerebral cortex

Our cerebral cortex, or pallium, is a big part of what makes us human: art, literature and science would not exist had this most fascinating part of our brain not emerged in some less intelligent ancestor in prehistoric times. But when did this occur and what were these ancestors? Unexpectedly,…

SCIENCE & TECHNOLOGY

2010

sciencescience-technology

25 August 2010

Freeze or run? Not that simple

Fear can make you run, it can make you fight, and it can glue you to the spot. Scientists at the European Molecular Biology Laboratory (EMBL) in Monterotondo, Italy and GlaxoSmithKline in Verona, Italy, have identified not only the part of the brain but the specific type of neurons that determine…

SCIENCE & TECHNOLOGY

2010

sciencescience-technology

4 July 2010 The Fly Digital Embryo at different developmental stages, with cell nuclei coloured according to how fast they were moving (from blue for the slowest to orange for the fastest). The fruit fly embryo is magnified around 250 times. IMAGE: Philipp Keller

The Fly Digital Embryo at different developmental stages, with cell nuclei coloured according to how fast they were moving (from blue for the slowest to orange for the fastest). The fruit fly embryo is magnified around 250 times. IMAGE: Philipp Keller

Digital Embryo gains wings

The scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, who ‘fathered’ the Digital Embryo have now given it wings, creating the Fly Digital Embryo. In work published today in Nature Methods, they were able to capture fruit fly development on film, and were the…

SCIENCE & TECHNOLOGY

2010

sciencescience-technology

4 July 2008

New research sheds light on the molecular basis of crib death

Sudden Infant Death Syndrome (SIDS) is a condition that unexpectedly and unexplainably takes the lives of seemingly healthy babies aged between a month and a year. Now researchers of the European Molecular Biology Laboratory in Monterotondo, Italy, have developed a mouse model of the so-called crib…

SCIENCE & TECHNOLOGY

2008

sciencescience-technology

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