Cute molecules and the scientists who adore them: Veijo Salo
People & Perspectives Veijo Salo, postdoc at EMBL Heidelberg, talks about seipin, the cell’s molecular ‘bubble blower’.
2024
people-perspectives
What we can learn from hungry yeast cells
Science & Technology Scientists at EMBL Heidelberg and University of Virginia revealed a new cellular response to starvation: ribosomes attach to the mitochondrial outer membrane in a very unusual way, via their small subunit. The finding made in yeast might provide insights into how cancer cells survive the harsh…
2024
science-technology
The forces behind chromosome repulsion and attraction during cell division
Science & Technology EMBL Heidelberg researchers discovered how a protein switches between repelling and gluing chromosomes during cell division. This helps the mother cell to divide the genome equally into two daughter cells and cluster chromosomes inside the daughter nuclei, ensuring a successful cell division.
2024
science-technology
Structure and function of new lysosome transporter revealed
Science & Technology The group of Christian Löw at EMBL Hamburg and CSSB, and collaborators from the Christian-Albrechts-University Kiel and CNRS & Université Paris Cité worked together to reveal the structure and function of a previously unknown lysosome transporter, MFSD1.
2024
science-technology
Exploring diversity in cell division
Science & Technology New research by EMBL scientists shows how different modes of cell division used by animals and fungi might have evolved to support diverse life cycles.
2024
science-technology
Understanding how cells avoid obstacles
Science & Technology EMBL researchers have identified a novel mechanism that allows cells to sense obstacles in their path and avoid them while navigating complex environments.
2023
sciencescience-technology
New therapies to improve cardiovascular health
Science & Technology EMBL researchers have made new strides into understanding and reversing genetic defects that underlie familial heart disease.
2023
sciencescience-technology
The power of cell sorting: understanding heart disease, phase separation, plankton, and more
Science & Technology EMBL researchers use a new cell sorting technology to gain new insights into cellular function in health and disease, as well as for other innovative applications.
2023
sciencescience-technology
The hairy single-celled Tetrahymena provides a work reset
Lab MattersScience & Technology Dey Group holds second annual ‘labbatical’ to step outside daily research tasks with the help of single-celled model organisms.
2023
lab-mattersscience-technology
Spotlight: A giant in action
Science & Technology Physarum polycephalum, a single, giant cell containing tens of thousands of nuclei is large enough to be photographed with a phone.
2022
picture-of-the-weekscience-technology
Cell sorting enters a new dimension
Science & Technology EMBL researchers, in collaboration with BD Biosciences, have demonstrated a new technology that allows rapid image-based sorting of cells. The new technology represents a major upgrade to flow cytometry and has applications in diverse life science fields.
2022
sciencescience-technology
A gallery of human RNA polymerases
Science & Technology New structural biology research provides fundamental information critical to understanding enzyme mutations connected to rare diseases and cancers.
2021
sciencescience-technology
Welcome: Niccolò Banterle
Lab MattersPeople & Perspectives Using gene editing and three types of microscopy, one of EMBL’s newest group leaders is deciphering the functions of one of the smallest molecules involved in cell division, motility, and signalling, known as a centriole.
2021
lab-matterspeople-perspectives
Analysis and sorting with flow cytometry
Lab MattersScience & Technology A technology around since the ‘60s, flow cytometry has increasing applications. New leadership at EMBL’s flow cytometry facilities is looking to ease use, expand training, and encourage more collaboration.
2021
lab-mattersscience-technology
When ‘good’ cells go ‘bad’
Science & Technology If researchers can identify specifically when good cells go bad, they can potentially understand disease better.
2021
sciencescience-technology
A cellular atlas of an entire worm
Science & Technology EMBL scientists and colleagues have developed an interactive atlas of the entire marine worm Platynereis dumerilii in its larval stage. The PlatyBrowser resource combines high-resolution gene expression data with volume electron microscopy images.
2021
sciencescience-technology
Cryo-Electron Microscopy Service Platform supports research on protein transport
Lab MattersScience & Technology Giulia Zanetti from the Institute of Structural and Molecular Biology (ISMB) in London explains how the collaboration with the Cryo-Electron Microscopy Service Platform enabled her group to reveal the structure of protein transport complexes.
2021
lab-mattersscience-technology
Welcome: Anna Erzberger
Lab MattersPeople & Perspectives Anna Erzberger, one of EMBL’s newest group leaders, will provide unique perspective as a theoretical biological physicist.
2021
lab-matterspeople-perspectives
Nuclear twins
Science & Technology Captured by EMBL postdoc Arina Rybina, these ‘nuclear twins’ are two daughter nuclei straight after division of a HeLa cell.
2021
picture-of-the-weekscience-technology
SARS-CoV-2 curtails immune response in the gut
Science & Technology EMBL scientists, together with collaborators from Heidelberg University, have provided further evidence of the gut’s role in COVID-19.
2021
sciencescience-technology
Painting liver cells
Science & Technology A page from a biologist’s colouring book? EMBL’s new interior wall design? Not quite – a bunch of liver cells, grown in the lab so that scientists can learn about fatty liver disease, or steatosis.
2021
picture-of-the-weekscience-technology
At the core of the Integrator complex
Science & Technology A new paper from the Galej group at EMBL Grenoble describes the structure of key parts of the Integrator complex, involved in gene expression.
2021
sciencescience-technology
EMBL group leader Miki Ebisuya receives ERC Consolidator Grant
EMBL AnnouncementsLab Matters Funding by the European Research Council (ERC) will support research on the timing of developmental processes in mammals
2020
embl-announcementslab-matters
Scratching the surface on cell differentiation
Science & Technology Scientists in the Diz-Muñoz group at EMBL Heidelberg are working to build understanding of the role that mechanical properties play in affecting cell behaviour – a young and rapidly developing field of study. They have developed and successfully used a highly specialised technique to manipulate…
2020
sciencescience-technology
Party at the nucleus?
Science & Technology The nucleus of this cell fluoresces in bright green thanks to GFP-labelled nucleoporin proteins. EMBL scientists use engineered nucleoporins as 3D reference standards to improve super-resolution microscopy.
2020
picture-of-the-weekscience-technology
Human and mouse cells run at different speeds
Science & Technology The internal clock that governs the development of embryos ticks slower for humans than for mice. Differences in the speed of biochemical reactions underlie the differences between species in the tempo of development.
2020
sciencescience-technology
A tool to improve cancer research
Science & Technology EMBL scientists have created a new, realistic 3D testbed that could help achieve the goal of stopping cancers before they start by studying cancer cells as they first form.
2020
sciencescience-technology
Taking a closer look at infected cells to better understand COVID-19
Science & Technology EMBL electron microscopy specialists collaborate with researchers from Heidelberg University Hospital to understand the changes occurring in cell structures upon SARS-CoV-2 infection.
2020
sciencescience-technology
Machine learning finds critical phosphosites
Science & Technology Resource has implications for disease research
2019
sciencescience-technology
Photo-micropatterning advances structural cell biology
Science & Technology A new technique in cryo-EM
2019
sciencescience-technology
ATP affects proteome-wide solubility
Science & Technology Scientists develop technology to measure how ATP concentration affects protein solubility in cells
2019
sciencescience-technology
Understanding early embryo development in mice
Science & Technology How organs form in a mouse embryo
2019
sciencescience-technology
EMBL in the UK: Wendy Bickmore
People & Perspectives Meet Wendy Bickmore, Director of the MRC Human Genetics Unit, who spoke at the EMBL in the UK event
2018
alumnipeople-perspectives
EMBL in Finland: Marja Makarow
Connections Scientists in Finland met to share ideas and discover research opportunities
2018
alumniconnections
The proteins behind hungry cells
Science & Technology EMBL researchers visualise the proteins needed to capture molecules and bring them into a cell
2018
sciencescience-technology
Welcome: Miki Ebisuya
People & Perspectives New group leader at EMBL Barcelona creates artificial biological systems to study animal development
2018
people-perspectivesscience
EMBL in Italy: Kristina Havas-Cavalletti
People & Perspectives More than 80 attendees gathered at the EMBL in Italy event at the FIRC Institute of Molecular Oncology (IFOM) in Milan
2018
alumnipeople-perspectives
Melina Schuh receives EMBO Gold Medal
People & Perspectives EMBL alumna Melina Schuh recognised for excellence in science
2018
alumnipeople-perspectives
New software makes 3D imaging accessible
Science & Technology Open-source software allows standard microscopes to accurately image 3D structures
2018
sciencescience-technology
Counting condensins on chromosomes
Science & Technology EMBL scientists count and locate chromosomal proteins during cell duplication
2018
sciencescience-technology
From blood vessels to blood stem cells
Science & Technology EMBL scientists discover how blood vessel cells become blood stem cells during embryonic development
2018
sciencescience-technology
DNA replication stress in cancer
Science & Technology Thanos Halazonetis discusses the EMBO/EMBL Symposium: DNA Replication: From Basic Biology to Disease
2018
eventsscience-technology
Welcome: Sara Cuylen-Häring
People & Perspectives New EMBL group leader explores biophysical properties of chromosomes and other cellular assemblies
2018
people-perspectivesscience
Welcome: Aissam Ikmi
People & Perspectives New group leader studies sea anemones to investigate why some animals regenerate better than others
2018
people-perspectivesscience
Chromosomes don’t need key protein for all their folds
Science & Technology New research reveals that two different mechanisms are responsible for chromosome folding
2017
sciencescience-technology
Cells grow pores from shrinking holes
Science & Technology New research shows how pores form in the membrane that surrounds a cell’s nucleus
2017
sciencescience-technology
Science in space
People & Perspectives EMBL alumna Sigrid Reinsch trained as a cell biologist – now she helps run experiments in space
2017
alumnipeople-perspectives
Research highlights
Science & Technology A summary of recent research highlights from EMBL
2017
sciencescience-technology
Looping the loops: how chromosomes form
Science & Technology EMBL researchers and collaborators unravel how chromosomes form
2017
sciencescience-technology
Welcome: Justin Crocker
People & Perspectives Meet Justin Crocker, EMBL’s new group leader in gene regulation during evolution and development
2017
people-perspectivesscience
40 years of electron microscopy training at EMBL
Lab Matters Celebrating 40 years since the first EMBO electron microscopy training course
2017
eventslab-matters
Open imaging data for biology
Science & Technology The Image Data Resource - prototype of the first open repository linking imaging and molecular data
2017
sciencescience-technology
Mapping gene expression, cell by cell
Science & Technology EMBL researchers complete a molecular atlas showing gene expression in all cells in an entire animal
2017
sciencescience-technology
Senses: Silencing noise
Science & Technology Two EMBL researchers are exploring new ways to filter out noise and get to the data they need
2017
sciencescience-technology
Cell changes drive breast cancer relapse
Science & Technology Hallmarks of residual breat cancer cells suggest new approaches for preventing relapse
2017
sciencescience-technology
Futures: Phosphatases
Science & Technology ERC grantee Maja Köhn shares her vision for the next ten years
2017
sciencescience-technology
Illuminating insulin release
Science & Technology EMBL researchers develop an optical method for measuring the release of insulin from single cells
2017
sciencescience-technology
Structure of key system for TB infection
Science & Technology EMBL scientists add crucial knowledge to understanding of the bacterium that causes tuberculosis
2017
sciencescience-technology
Blood stem cell differentiation is continuous
Science & Technology Study by EMBL and DKFZ researchers means origins of myeloid leukaemias may need rethinking
2017
sciencescience-technology
Futures: Brain evolution
Science & Technology ERC grantee Detlev Arendt shares his vision for the next ten years
2017
sciencescience-technology
Futures: Genome regulation
Science & Technology ERC grantee Eileen Furlong shares her vision for the next ten years
2017
sciencescience-technology
Unlocking the secrets of nuclear movements
Science & Technology EMBL researchers develop a computer model to explore the movement of nuclei in a multinuclear cell
2017
sciencescience-technology
Building labs with flies
People & Perspectives Flies can do a lot for science, inside and outside the lab. EMBL alumna Isabel Palacios explains how
2017
alumnipeople-perspectives
Study offers approach to treating pain
Science & Technology Research on the effect of nerve cell stiffness on sensitivity to touch could lead to new painkillers
2016
sciencescience-technology
Cycle of life
Science & Technology Paul Nurse’s failed experiment inspired a career that would uncover key mechanisms of cell division
2016
sciencescience-technology
Design for life
Lab MattersPeople & Perspectives EMBL’s Petra Riedinger retires after 40 years producing posters, graphics, artwork and more
2016
lab-matterspeople-perspectives
Chromatin cartographer
People & Perspectives EMBL alumnus Jop Kind reflects on the questions that led him to this year’s John Kendrew Award
2016
alumnipeople-perspectives
New insights into RNA Polymerase I
Science & Technology Cryo EM reconstruction of RNA Polymerase I reveals details of how molecule binds and transcribes DNA
2016
sciencescience-technology
Welcome to EMBL: Robert Prevedel
People & Perspectives Robert Prevedel develops deep-tissue microscopy for scientists to peer deep inside living organisms
2016
people-perspectivesscience
Watching nuclear pores in growing nuclei
Science & Technology Puzzle of nuclear pore formation in growing nuclei solved
2016
sciencescience-technology
New tool to control information relay in cells
Science & Technology Molecular messengers synthesised to help study how cells respond to outside stimuli
2016
sciencescience-technology
Welcome: Alba Diz-Muñoz
People & Perspectives New group leader combines physics and biology to answer the 'hows' of cell movement
2016
people-perspectivesscience
How cells bag their rubbish
Science & Technology How cells eliminate protein deposits that can lead to neurodegenerative disorders
2016
sciencescience-technology
Making cells move towards the light
Science & Technology New method enables scientists to use light to direct where cancer cells go
2016
sciencescience-technology
The rhythms in life
Science & Technology How EMBL scientists are discovering and understanding the waves and rhythms inside us
2016
sciencescience-technology
Mothers and daughters
Science & Technology 1st real-time video of starfish egg cell eliminating crucial structures, to ensure embryo viability
2016
sciencescience-technology
Forever young
Science & Technology How stem cells resist change
2016
sciencescience-technology
SPIM doctors
Science & Technology From initial development to a start-up company: Selective Plane Illumination Microscopy (SPIM) at EMBL.
2015
sciencescience-technology
Lighting up development
Science & Technology Using lasers to shed light on how tissues get into shape
2015
sciencescience-technology
One hard pull
Science & Technology Fibres that pull membrane to form a vesicle exert a force that’s 2500 times a yeast cell’s own weight
2015
sciencescience-technology
Karsenti wins CNRS gold
EMBL AnnouncementsLab Matters Gold medal celebrates Eric Karsenti’s exceptional career and outstanding contributions to biology.
2015
embl-announcementslab-matters
Cellular synergy
People & Perspectives Alumnus Thomas Vaccari reflects on the first joint symposium with EMBL Monterotondo, in Milan.
2015
eventspeople-perspectives
First, find your membrane
Science & Technology Collaboration between scientists reveals collaboration between lipids.
2015
sciencescience-technology
Cell machinery wears complex coat
Science & Technology 3D imaging unravels COPI coat of cells' transport vesicles.
2015
sciencescience-technology
Decades-old cell biology puzzle solved
Science & Technology Behaviour of clathrin proteins, crucial for endocytosis, is clarified using new imaging techniques.
2015
sciencescience-technology
Dancing with the cells
Science & Technology Cells 'dance' as they draw together during early embryo development.
2015
sciencescience-technology
Sense of space
Science & Technology EMBL scientists demonstrate that spatial constraints are a key factor in determining nucleus size.
2015
sciencescience-technology
Destination collaboration
Science & Technology Stanford University biophysicist KC Huang on his collaboration with the Typas group in Heidelberg.
2015
sciencescience-technology
How cells have got molecules surrounded
Science & Technology Ground-breaking microscopy technique gives unprecedented insight into endocytosis.
2015
sciencescience-technology
No humans required
Science & Technology New fully automated technique enables scientists to chart complex protein networks in living cells.
2015
sciencescience-technology
Best of three worlds
Science & Technology Combining three different kinds of microscopy to determine how molecules move during endocytosis.
2015
sciencescience-technology
Under pressure
Science & Technology How strong does a spindle need to be? Videos put cell’s chromosome-separating machinery to the test
2015
sciencescience-technology
Beyond sequencing
Science & Technology New microscopy-based method goes beyond gene sequencing, pinpointing the cause of disease.
2015
sciencescience-technology
Awards & Honours
Lab Matters EMBL scientists regularly receive prestigious awards – meet the latest honourees.
2015
lab-matters
Bacteria’s barrel-building challenge
Science & Technology How do E.coli and similar bacteria grow safely? By using barrel-plugs as sensors.
2014
sciencescience-technology
How to fix a cellular powerhouse
Science & Technology Compound that can restore the function of poorly working mitochondria, with therapeutic potential.
2014
sciencescience-technology
Polish connections
Lab Matters Alumna Anna Bartosik shares insights and hopes for EMBL's newest prospect member state, Poland.
2014
alumnilab-matters
Chamber of secrets
Science & Technology Like sports teams, cells can huddle to communicate in secret and organise group behaviour
2014
sciencescience-technology
Breaking boundaries
Science & Technology How Nobel-winning work by alumnus Stefan Hell shapes and inspires current EMBL scientists' research.
2014
sciencescience-technology
Go with the flow
Science & Technology Flow cytometry: finding needles in haystacks
2014
sciencescience-technology
Major advance in stem cell technology
Science & Technology Researchers produce pristine stem cells, which can be precisely changed into clinically relevant cell types.
2014
sciencescience-technology
Drawing on nature
PhD Symposium poster reveals how a cell’s inner workings serve as both inspiration and toolkit.
2014
events
Binding bracelet
Science & Technology Vasa protein preserves pieces of 'enemy' DNA to help protect the genes of future generations.
2014
sciencescience-technology
Embracing cellular complexity
Science & Technology Cell biologists "underestimate the complexity" of protein interactions, says Toby Gibson.
2014
sciencescience-technology
Picky eaters: how microglia capture their prey
Science & Technology A kaleidoscope of molecules is needed to clean up dead brain cells, and failure can have disastrous consequences
2014
sciencescience-technology
First, catch your DNA
Science & Technology DNA-coralling protein complex in an unexpected bind
2014
sciencescience-technology
How immune cells use steroids
Science & Technology Genome Campus researchers discover that some immune cells turn themselves off by producing a steroid.
2014
sciencescience-technology
Movies for the human genome
Science & Technology Name a human gene, and you’ll find a movie online showing you what happens to cells when it is switched off. This is the resource that researchers at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and their collaborators in the Mitocheck consortium are making freely…
2010
sciencescience-technology
A clearer view on biology
Science & Technology The European Molecular Biology Laboratory (EMBL) has developed a new computational tool that makes images obtained with cutting-edge microscopes even sharper. The technological advance and its applications are published in this week’s online issue of the journal Nature Methods. Since the…
2007
sciencescience-technology
How nature tinkers with the cellular clock
Science & Technology The life of a cell is all about growing and dividing at the right time. That is why the cell cycle is one of the most tightly regulated cellular processes. A control system with several layers adjusts when key components of the cell cycle machinery are produced, activated and degraded to make sure…
2006
sciencescience-technology
Biology in four dimensions
Science & Technology Most things that happen in the cell are the work of ‘molecular machines’ – complexes of proteins that carry out important cellular functions. Until now, scientists didn’t have a clear idea of when proteins form these machines – are these complexes pre-fabricated or put…
2005
sciencescience-technology
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