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Tag:

chromatin

Showing 1 - 10 results out of 17

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3 July 2020 stem cells neurons differentiation

From stem cells to neurons

Scientists at EMBL Heidelberg have investigated stem cells and how they differentiate to become neurons. Their approach included an assessment of the complex interplay of molecules during the differentiation process and generated fundamental new insights into the role of a protein called Sox2 in…

SCIENCE & TECHNOLOGY

2020

sciencescience-technology

22 May 2020

EMBL scientists investigate rare lung disease

Researchers in EMBL’s Zaugg group have studied the causes of pulmonary arterial hypertension (PAH), a rare disease that causes high blood pressure in the arteries of the lungs. The study, carried out in collaboration with Stanford University School of Medicine, compared lung cells of patients…

SCIENCE & TECHNOLOGY

2020

sciencescience-technology

28 April 2020

Dancing chromosomes

In human cells, the genetic material is packaged into 23 different DNA molecules, the chromosomes. Each chromosome is present in two copies, one inherited from the paternal sperm, and the other from the maternal egg. During most of the cell’s life, chromosomes take the shape of long,…

SCIENCE & TECHNOLOGY

2020

picture-of-the-weekscience-technology

15 July 2019 The pyramids represent chromatin domains in the wild-type situation. The reflection in the water below represents the rearrangements in the mutant fruit fly chromosomes. At first glance the (regulatory) landscapes look very similar, but there are lots of changes to the topology, and yet these have little impact on the nature of the landscape (gene expression). IMAGE: Beata Edyta Mierzwa in collaboration with EMBL.

Rearranging chromosomes

Does rearranging chromosomes affect their function? EMBL scientists reveal uncoupling of 3D chromatin organisation and gene expression.

SCIENCE & TECHNOLOGY

2019

sciencescience-technology

30 May 2008

X chromosome exposed

Researchers from the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and the EMBL-European Bioinformatics Institute (EMBL-EBI) in Hinxton, UK, have revealed new insights into how sex chromosomes are regulated. A chromatin modifying enzyme helps compensate for the fact that…

SCIENCE & TECHNOLOGY

2008

sciencescience-technology

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