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crispr

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21 January 2022 The cross-section of a cell expressing a green fluorescently tagged protein and illuminated by a blue laser is visible in the foreground, surrounded by a vortex of cells

Cell sorting enters a new dimension

Science & Technology EMBL researchers, in collaboration with BD Biosciences, have demonstrated a new technology that allows rapid image-based sorting of cells. The new technology represents a major upgrade to flow cytometry and has applications in diverse life science fields.

2022

sciencescience-technology

9 September 2021 A student in front of a computer watches a scientist working in a laboratory

New horizons for virtual learning

Lab Matters EMBL's science education department makes the latest scientific research more accessible for teachers and students.

2021

eventslab-matters

3 July 2020 stem cells neurons differentiation

From stem cells to neurons

Science & Technology Scientists at EMBL Heidelberg have investigated stem cells and how they differentiate to become neurons. Their approach included an assessment of the complex interplay of molecules during the differentiation process and generated fundamental new insights into the role of a protein called Sox2 in…

2020

sciencescience-technology

2 July 2020 epigenetic reprogramming, epigenetic memory, Hackett group

Unravelling epigenetic reprogramming

Science & Technology A study conducted by the Hackett group at EMBL Rome has identified key factors controlling the complex system of gene regulation during early embryo development, shedding new light on the mechanisms behind these events and on their evolutionary implications. Their findings are published in Nature…

2020

sciencescience-technology

25 June 2020 Scientists in the Hackett group at EMBL Rome doing lab work

Silencing the SARS-CoV-2 receptor with epigenetic modifications

Science & Technology EMBL scientists develop a new molecular tool to prevent SARS-CoV-2 infection in mice. This tool is able to cause targeted epigenetic modifications of specific genes in specific cell populations. They will use it in mice to target airway cells that express the ACE2 protein – the receptor that…

2020

sciencescience-technology

1 June 2020 An illustration of single-cell RNA sequencing (scRNA-seq)

Enabling functional genomics studies in individual cells

Science & Technology Scientists at EMBL Heidelberg have developed a new method, called Targeted Perturb-seq (TAP-seq), which increases the scale and precision of functional genomics CRISPR–Cas9 screens by orders of magnitude. Their method overcomes limitations in previous applications of single-cell RNA sequencing,…

2020

sciencescience-technology

15 May 2020 Cell division

Tracing the origins of cells

Science & Technology Researchers from the Sharpe group at EMBL Barcelona have published a method to track the developmental history of a cell using the gene editing tool CRISPR–Cas9, but without the need to create transgenic organisms.

2020

sciencescience-technology

29 November 2019 Choanocyte chamber of sponge, with neuroid cell

Neural pathways

Science & Technology Exploring the diverse routes by which EMBL scientists are driving forward neurobiology

2019

sciencescience-technology

9 July 2019 A model of CRISPR/Cas9

Wielding the genetic scissors

Science & Technology What CRISPR may bring for the future of biology, and how it is used at EMBL

2019

sciencescience-technology

21 September 2017

Fish on fire

Science & Technology New study by Paola Kuri and Maria Leptin shows how inflammation happens in zebrafish in real time

2017

sciencescience-technology

30 August 2016

Gene editing 3.0

Science & Technology Emmanuelle Charpentier sheds light on how CRISPR–Cas9 went from side project to global revolution

2016

sciencescience-technology

14 October 2015 single-cell transcriptomics reveals biologically relevant heterogeneity in expression

A snapshot of stem cell expression

Science & Technology Study of mouse embryonic stem cells reveals new genes involved in the stem-cell regulatory network.

2015

sciencescience-technology

26 January 2015

Awards & Honours

Lab Matters EMBL scientists regularly receive prestigious awards – meet the latest honourees.

2015

lab-matters

1 July 2014

Nothing but blue skies

Science & Technology Focusing on basic research is crucial for the development of more advanced genetics techniques

2014

sciencescience-technology

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