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cusack

Year
24 May 2024

Stephen Cusack: what I’ve learned

People & Perspectives Stephen Cusack, world-renowned structural biologist and former Head of EMBL Grenoble, reflects on his early influences, his achievements, and the lessons he’s learned as he embarks on his next adventure

2024

people-perspectives

26 October 2023

A promising target to fight inflammatory bowel diseases

Science & Technology Researchers from the Cusack group at EMBL Grenoble provide structural insights on the XIAP/RIPK2 complex, a promising drug target to fight inflammatory bowel diseases.

2023

sciencescience-technology

15 September 2023 Group of scientists attending symposium staring upward to the photographer.

Celebrating Stephen Cusack’s contributions to science

People & Perspectives Researchers from across the globe have gathered in Grenoble to celebrate the remarkable lifelong scientific achievements of Stephen Cusack, the former head of EMBL Grenoble.

2023

eventspeople-perspectives

17 June 2020 Crystal selection for X-ray diffraction experiments.

Investigating the structure and mechanisms of coronavirus biomolecules

Science & Technology While global research on coronaviruses has shed light on the function of many SARS-CoV-2 proteins, the role of some crucial components remains unknown. Researchers at EMBL Grenoble will use a range of structural biology methods to try to solve some of the puzzles of the molecular mechanics of…

2020

sciencescience-technology

29 April 2020 The Influenza virus

Understanding the influenza virus

Science & Technology The infectious disease commonly known as flu is caused by the influenza virus. It spreads around the world in seasonal outbreaks, causing millions of infections and hundreds of thousands of deaths each year. Stephen Cusack, Head of EMBL Grenoble, has been studying different aspects of the influenza…

2020

sciencescience-technology

20 December 2017 In this representation of influenza polymerase, a molecule (white) that strongly inhibits the enzyme’s activity is shown bound to the region of the enzyme (red) that usually binds the cap section of mRNA. IMAGE: EMBL/Cusack Group

Futures: Unravelling influenza

Science & Technology ERC grantee Stephen Cusack shares his vision for the next ten years

2017

sciencescience-technology

21 December 2016

How flu steals your RNA

Science & Technology Understanding how the flu virus steals host RNA offers hope of new drugs

2016

sciencescience-technology

14 December 2016

New Crystallography platform inaugurated

EMBL AnnouncementsLab Matters A new crystallography platform in Grenoble opens the door to new technological developments

2016

embl-announcementslab-matters

13 September 2016

New drug candidate unleashed for TB

Science & Technology EMBL researchers help to design a lead compound active against four different pathogens

2016

sciencescience-technology

13 September 2016

Opinion: 2006, a year of champagne

Lab MattersPeople & Perspectives Stephen Cusack looks back on the early days of his collaboration with Anacor developing anti-infectives

2016

lab-matterspeople-perspectives

16 June 2016 Emiko Uchikawa in her lab at EMBL in Grenoble. IMAGE: Isabelle Kling/EMBL

Found in translation

Science & Technology Studying at EMBL in Grenoble helps Japanese postdoc see her native country through different eyes

2016

sciencescience-technology

24 August 2015

Molecular momentum

People & Perspectives Andrew Miller, first head of EMBL Grenoble, reflects on four decades at the Outstation.

2015

alumnipeople-perspectives

24 August 2015

Awards & Honours

EMBL AnnouncementsLab Matters EMBL scientists regularly receive prestigious awards – meet the latest honourees.

2015

embl-announcementslab-matters

18 June 2015

From mountains to molecules

Staff, alumni, partners and more meet at EMBL Grenoble to celebrate Outstation's 40th anniversary.

2015

events

21 May 2015

It runs in the family

Detailed structural study shows distantly related viruses share a common machinery for replication.

2015

science

19 November 2014

20 years in the making

Science & Technology First complete picture of flu virus polymerase. A story of two decades of blood, sweat and sneezes.

2014

sciencescience-technology

20 August 2014

Binding bracelet

Science & Technology Vasa protein preserves pieces of 'enemy' DNA to help protect the genes of future generations.

2014

sciencescience-technology

1 July 2014

The future’s bright

Science & Technology Surprising protein from a flu-like virus is 10 000th ESRF structure

2014

sciencescience-technology

13 October 2011 In the absence of viral RNA (top), the part of RIG-I that senses viral RNA is exposed (orange), whilst the domains responsible for signalling (blue and pink) are out of reach of the signalling machinery. When RIG-I detects viral RNA, it changes shape (bottom), and the signalling domains become accessible to sound the alarm.

Intruder detected: raise the alarm!

Science & Technology When a thief breaks into a bank vault, sensors are activated and the alarm is raised. Cells have their own early-warning system for intruders, and scientists at the European Molecular Biology Laboratory (EMBL) in Grenoble, France, have discovered how a particular protein sounds that alarm when it…

2011

sciencescience-technology

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