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developmental biology

Year
31 October 2024 Woman with crossed arms stands in front of tree

Welcome: Isabella Graf

People & Perspectives Isabella Graf is EMBL’s newest group leader and the first theoretical biophysicist to join the Developmental Biology Unit.

2024

people-perspectives

14 August 2024

Merging passion, collaboration, and serendipity

People & Perspectives EMBL alumnus Thibaut Brunet, recipient of the 2024 John Kendrew Young Scientist Award, shares his scientific journey – from a childhood passion for nature to the discovery of a new species of choanoflagellate.

2024

people-perspectives

18 June 2024 A progression of three images against a blue/purple background. Each image shows a simulated mouse embryo inner cell mass with two types of cells marked in pink and green respectively. From the first to the third image, the pink cells slowly move from the outer edge to the inside of the mass.

Minecraft-ing our way into studying cell sorting

Science & Technology A theoretical model involving tiny Minecraft-like cubes can help us understand dynamic biological processes, such as cell sorting in embryos.

2024

science-technology

23 April 2024 This image showcases a processor with neon lights and abstract shapes that represent the flow and integration of spatial omics information. The background shows the analyzed and annotated breast cancer sample.

A universal framework for spatial biology

Science & Technology SpatialData is a tool developed by EMBL scientists in cooperation with multiple research institutions to unify and integrate data from different omics technologies in a spatial environment, providing holistic insights into health and disease. Researchers can now freely access and use SpatialData…

2024

science-technology

11 March 2024 Casting new light on gene regulation in development

Casting new light on gene regulation in development

Science & Technology New research from EMBL Heidelberg shows how cells in developing embryos undergo a major shift in the way they regulate gene expression as they mature and differentiate.

2024

sciencescience-technology

12 February 2024 Female scientist stands in front of white shelves filled with vials of fruit flies

Anne Ephrussi: what I’ve learned

Lab MattersPeople & Perspectives After 32 years at EMBL – leading a developmental biology research group and later simultaneously serving as EMBL’s Dean for its PhD programme, Anne Ephrussi has retired, ready to start her life’s next chapter.

2024

lab-matterspeople-perspectives

15 November 2023

Why time is of the essence in development

EMBLetc EMBL developmental biologists – with help from other disciplines – pursue the significance of time, timing, and transitions in organisms during their development

2023

27 October 2023 The image shows a uerine environment made of a jelly-like and transparent material, with a cylindrical 3D structure.

Spotlight: Creating an artificial uterus

Science & Technology EMBL researchers have created an engineered uterus that allows a closer look at a mouse embryo’s development and its interactions with the uterine environment.

2023

picture-of-the-weeksciencescience-technology

13 February 2023 Female scientist stands in front of lab bench

Welcome: Hanh Vu

Lab MattersPeople & Perspectives Group Leader Hanh Vu studies ‘immortal’ flatworms that can grow and de-grow to understand better factors that determine organisms’ sizes.

2023

lab-matterspeople-perspectives

20 January 2023 bright yellow and striped flatworms

Spotlight: A ‘devil’ of a flatworm

Lab MattersScience & Technology Tasmanian flatworms add to an EMBL researcher’s collection as she studies principles that control animal body size.

2023

lab-matterspicture-of-the-weekscience-technology

21 November 2022 male scientist in green shirt and dark pants stands outside in front of tree

Welcome Jordi van Gestel

Lab MattersPeople & Perspectives Looking to understand microbial predator-prey relationships, EMBL’s newest group leader tackles a molecular ‘arms race’ in his lab.

2022

lab-matterspeople-perspectives

21 October 2022 A female scientist in a blue dress stands in front of blurred woodsy background

Welcome: Flora Vincent

Lab MattersPeople & Perspectives After a postdoc at Weizmann Institute of Science in Israel, Flora Vincent has joined EMBL’s Developmental Biology unit to further explore the world of phytoplankton.

2022

lab-matterspeople-perspectives

4 August 2022 An illustration provides representation of fingers hovering over a cell phone

Zooming in to get the full picture

Science & Technology EMBL and UW researchers plus additional collaborators have constructed a complete map of fruit fly embryonic development using machine learning. This research is foundational to better understanding overall embryo development in other species, including humans.

2022

sciencescience-technology

4 March 2022 A gloved hand holds a slide with visible wells containing Matrigel immersed in culture medium. A magnified close-up shows a mouse embryo developing over the course of 48 hours

A 3D culture model to study embryo growth

Science & Technology A recent study by EMBL researchers proposes a new method to grow early embryos in the laboratory. With a 3D culture set-up, scientists can closely monitor the changes embryos undergo around the time of implantation.

2022

sciencescience-technology

25 February 2022 Three colourful overlapping circles arranged in a row, a fruit-fly embryo being visible within each. Small circles within the embryos represent cell lineages.

Converging lenses on embryo development

Science & Technology Researchers from the Furlong group at EMBL have come up with a way to observe the development of fruit-fly embryos simultaneously at the genetic and cellular levels, generating a high-resolution and integrated view of how different cell lineages form.

2022

sciencescience-technology

5 October 2021 Illustration of a globe with colourful shapes and symbols superimposed.

A cellular atlas of an entire worm

Science & Technology EMBL scientists and colleagues have developed an interactive atlas of the entire marine worm Platynereis dumerilii in its larval stage. The PlatyBrowser resource combines high-resolution gene expression data with volume electron microscopy images.

2021

sciencescience-technology

6 September 2021 Cells organised according to their transcript data changing to the seqFISH mouse embryo map.

The Spatial Mouse Atlas: new insights into cell fate

Science & Technology Researchers have combined spatial gene expression information with single-cell genomics data to create a high-resolution atlas of mouse organogenesis.

2021

sciencescience-technology

12 July 2021 Close-up illustration of the Kinesin-1 protein, intertwined with the aTm1 protein in a helix, next to loopy mRNA molecules.

A model of cooperation for transporting mRNA

Science & Technology EMBL scientists generate a high-resolution crystal structure of the Kinesin-1/aTm1 transport complex in the fruit fly.

2021

sciencescience-technology

2 July 2021 Portrait photo of a man in front of trees on a balcony

New head for EMBL’s Developmental Biology Unit

EMBL AnnouncementsLab Matters Dr Alexander Aulehla has been appointed the new Head of EMBL’s Developmental Biology Unit, and will take up the role starting in July 2021.

2021

embl-announcementslab-matters

8 July 2020 Alexander Aulehla on the left and Paul Flicek on the Right

Two EMBL scientists become EMBO Members

EMBL AnnouncementsLab Matters This year, EMBO elected 63 new members, including Alexander Aulehla, Group Leader and Senior Scientist at EMBL Heidelberg, and Paul Flicek, Associate Director of EMBL-EBI Services, Senior Scientist, Group and Team Leader at EMBL-EBI.

2020

embl-announcementslab-matters

19 May 2020 EMBL group leader Georgia Rapti

Welcome: Georgia Rapti

Lab MattersPeople & Perspectives The nervous system has fascinated Georgia Rapti ever since her first introduction to biology. Her research group in the Developmental Biology unit will focus on understanding the early biological events involved in the nervous system’s formation.

2020

lab-matterspeople-perspectives

3 August 2018 Optical section of a ‘gastruloid’ – an embryonic organoid made from mouse embryonic stem cells and stained for E-Cadherin (red), marking cell outlines and nuclei (blue). IMAGE: Vikas Trivedi/EMBL

Welcome: Vikas Trivedi

People & Perspectives An engineer’s approach to understanding morphogenesis

2018

people-perspectivesscience

20 March 2018 A heatmap graph displaying high (red) or low (blue) levels of gene expressions in different cells.

From blood vessels to blood stem cells

Science & Technology EMBL scientists discover how blood vessel cells become blood stem cells during embryonic development

2018

sciencescience-technology

19 December 2012

Sync to grow

Science & Technology Gene expression wave in the lower part of the future vertebrae column of a mammalian embryo. As the wave goes forward, new pre-vertebrae are formed and the future vertebrae column elongates. (Image and video credit: Nature) In a nutshell: The size of pre-vertebrae in a mammalian embryo is…

2012

sciencescience-technology

8 January 2012 Diagram of chromatin enhancers

Tracking genes’ remote controls

Science & Technology As an embryo develops, different genes are turned on in different cells, to form muscles, neurons and other bodily parts. Inside each cell’s nucleus, genetic sequences known as enhancers act like remote controls, switching genes on and off. Scientists at the European Molecular Biology Laboratory…

2012

sciencescience-technology

20 March 2011

The informant: a jumping gene

Science & Technology Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have developed a new method for studying gene regulation, by employing a jumping gene as an informant. Published online today in Nature Genetics, the new method is called GROMIT. It enables researchers to…

2011

sciencescience-technology

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