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4 March 2021 An illustration of single-cell RNA sequencing (scRNA-seq)

Induced pluripotent stem cells reveal causes of disease

Science, Science & Technology Scientists in the Stegle group and colleagues have studied induced pluripotent stem cells from around 1,000 donors to identify correlations between individual genetic variants and altered gene expression. They linked more than 4,000 of the genetic variants responsible for altered expression…

2021

sciencescience-technology

11 March 2020 Leukaemia stem cells are located in a patient’s bone marrow (shown here in blue) in the so-called stem cell niche. The green structure is the bone itself. Credit: Dr. Raphael Lutz, Haas Lab

€2.45 m to investigate leukaemia causes and therapies

EMBL Announcements, Science The Heidelberg-based LeukoSyStem consortium investigates leukaemia stem cells in acute myeloid leukaemia. The German Federal Ministry of Education and Research financially supports this collaboration between Heidelberg University Hospital, HI-STEM gGmbH, the German Cancer Research Center and EMBL.

2020

embl-announcementsscience

6 March 2011 By silencing genes two at a time in cells like these, the scientists can analyse the genes’ combined effects. In this microscopy image of human cells, nuclei are shown in red, cell membranes in green, and the cellular scaffolding in blue.

Suggesting genes’ friends, facebook-style

Science Scientists at the European Molecular Biology Laboratory (EMBL) and the German Cancer Research Centre (DKFZ), both in Heidelberg, Germany, have developed a new method that uncovers the combined effects of genes. Published online today in Nature Methods, it helps understand how different genes can…

2011

science

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