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electron microscopy

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29 January 2024 Man leaning against a wall

Welcome: Kyle Morris

Lab MattersPeople & Perspectives Kyle Morris joins EMBL-EBI as Electron Microscopy Data Bank (EMDB) Team Leader.

2024

lab-matterspeople-perspectives

14 November 2023 Blue thumbprint-sized ovals cluster together on a black background with white and pink dots sporadically situated on the blue ovals.

Five takeaways from ‘Seeing is believing’ in 2023

Science & Technology A recent EMBO | EMBL symposium brought together leading developers of imaging methods with cutting-edge applications that illustrate how imaging can answer biological questions.

2023

eventsscience-technology

5 October 2023 A composite image of four 3D micrographs showing the cellular organelles of a phytoplankton marked in different colours.

Spotlight: Seeing into the seas

Science & Technology A new method developed by EMBL scientists can help us identify and investigate plankton species in field samples with greater speed, accuracy, and resolution than ever possible before.

2023

sciencescience-technology

15 May 2023 A section of electron microscopy volume of a Platynereis larvae. Different colours mark different cell groups.

Visualising biology: new tools of the trade

EMBLetc EMBL researchers are pushing the frontiers of big data analysis in biological imaging, allowing scientists to gain a many-layered and multidimensional view of organisms, tissues, and cells in action.

2023

3 April 2023 Two male scientists with safety glasses at EMBL Imaging Centre

Dispensing microscopy expertise

Lab MattersScience & Technology Home to some of Europe’s most cutting-edge tools in molecular biology, EMBL has long shared its expertise and access to these tools through an extensive repertoire of courses, conferences, seminars, and other training. And now included in this mix is a job shadowing programme at EMBL Imaging…

2023

lab-mattersscience-technology

24 January 2022 Three women are seen in front of a computer, with the electron micrograph of a woodlouse visible on the screens

EMBL Imaging Centre kickstarts training with workshop for undergraduates

Lab Matters The new EMBL Imaging Centre held its first on-site training workshop, introducing undergraduate students to the basics of volume electron microscopy. This marks the first of many opportunities to aid capacity-building in imaging techniques in Europe.

2022

lab-matters

20 December 2021 A detailed structure map shows two proteins interacting in the foreground, each shown in a different colour. The background shows small green dots marking bacteria

Solving molecular puzzles to find the perfect fit

Science & Technology Using cryo-EM and structural biology techniques, EMBL researchers have shown how two proteins of Legionella pneumophila interact. This finding sheds light on a mechanism critical to the infection process and could lead to the development of new drugs to treat pneumonia.

2021

sciencescience-technology

9 December 2021 Colourful interwoven coils are displayed against a grid of small black and white photographic images.

A gallery of human RNA polymerases

Science & Technology New structural biology research provides fundamental information critical to understanding enzyme mutations connected to rare diseases and cancers.

2021

sciencescience-technology

5 November 2021 Three-dimensional rendering of sponge neuroid cells (coloured orange) and sponge digestive cells (coloured green).

More than a gut reaction

Science & Technology What can sponges tell us about the evolution of the brain? Sponges have the genes involved in neuronal function in higher animals. But if sponges don’t have brains, what is the role of these? EMBL scientists imaged the sponge digestive chamber to find out.

2021

sciencescience-technology

5 October 2021 Illustration of a globe with colourful shapes and symbols superimposed.

A cellular atlas of an entire worm

Science & Technology EMBL scientists and colleagues have developed an interactive atlas of the entire marine worm Platynereis dumerilii in its larval stage. The PlatyBrowser resource combines high-resolution gene expression data with volume electron microscopy images.

2021

sciencescience-technology

7 April 2021 Man standing next to painting

Welcome: Matthew Hartley

Lab MattersPeople & Perspectives The challenges and opportunities when setting up a global archive for bioimages

2021

lab-matterspeople-perspectives

19 January 2021 3D rendering of a human cell, attacked by a virus.

Cell under attack

Science & Technology It’s almost a year since the coronavirus outbreak was declared a pandemic, affecting all our lives. While the virus continues its grip on the world, scientists are understanding it better and better, increasing our knowledge about it and opening up new ways to fight it.

2021

picture-of-the-weekscience-technology

18 January 2021 man wearing sweater and glasses stands in front of snow and glassy building

Welcome: Timo Zimmermann

Lab MattersPeople & Perspectives The EMBL Imaging Centre is scheduled to open in 2021 with Timo Zimmermann as Team Leader for advanced light microscopy technology development and service provision.

2021

lab-matterspeople-perspectives

23 November 2020 Tube-like structures of a cell at sub-cellular level in red and grey.

Replication cycle of SARS-CoV-2 in 3D

Science & Technology Researchers have studied SARS-CoV-2 replication in cells and obtained detailed insights into the alterations induced in infected cells. This information is essential to guide the development of urgently needed therapeutic strategies for suppressing viral replication and induced pathology.

2020

sciencescience-technology

22 September 2020 Black and white electron microscope image of Anopheles mosquito gametes, looking much like feathery fern leaf stencils

A bloom of crystals

Science & Technology How does your crystal garden grow? EMBL's Electron Microscopy Core Facility was able to capture this garden of blooming crystals as they studied mosquito reproductive cells.

2020

picture-of-the-weekscience-technology

24 August 2020 Simone Mattei, the new team leader in electron microscopy service and technology development

Welcome: Simone Mattei

Lab MattersPeople & Perspectives The new team leader offering services in electron microscopy discusses his hopes and plans for the forthcoming EMBL Imaging Centre

2020

lab-matterspeople-perspectives

22 October 2018 An 88% complete model of human hemoglobin (PDB id 5ni1) built de novo by ARP/wARP into a 3.2 Å cryo-EM map. IMAGE: Victor Lamzin/EMBL

ARP/wARP 8.0 released

Lab MattersScience & Technology Researchers at EMBL Hamburg have released the next generation of their ARP/wARP software

2018

lab-mattersscience-technology

4 January 2018 Schematic reconstruction of the Robo1 structure. IMAGE: Andrew McCarthy / Structure

One way crossing across the midline

Science & Technology EMBL researchers solve a decades-long debate on a key process for brain and embryo-development

2018

sciencescience-technology

20 December 2017 In this representation of influenza polymerase, a molecule (white) that strongly inhibits the enzyme’s activity is shown bound to the region of the enzyme (red) that usually binds the cap section of mRNA. IMAGE: EMBL/Cusack Group

Futures: Unravelling influenza

Science & Technology ERC grantee Stephen Cusack shares his vision for the next ten years

2017

sciencescience-technology

16 November 2017 Photo of Jacques Dubochet giving a talk

A curious case of serendipity

People & Perspectives Jacques Dubochet, Nobel laureate and former EMBL group leader, reflects on a key aha moment

2017

alumnipeople-perspectives

25 January 2017 Wojciech Galej, new group leader at EMBL

Welcome: Wojciech Galej

People & Perspectives New group leader Wojciech Galej investigates RNA-protein complexes involved in gene expression

2017

people-perspectivesscience

17 November 2016

New insights into RNA Polymerase I

Science & Technology Cryo EM reconstruction of RNA Polymerase I reveals details of how molecule binds and transcribes DNA

2016

sciencescience-technology

21 March 2016 EMPIAR

Supporting the bioimaging revolution

Science & Technology Commentary in Nature Methods introduces the EMPIAR resource and gives glimpse of future developments

2016

sciencescience-technology

4 November 2014 EMPIAR logo

Building an EMPIAR

Science & Technology EMPIAR lets researchers take a closer look at the images used to build 3D molecular structures.

2014

sciencescience-technology

19 January 2010 Image credit: Rachel Melwig & Christine Panagiotidis / EMBL

Membrane-coat proteins: bacteria have them too

Science & Technology Although they are present almost everywhere, on land and sea, a group of related bacteria in the superphylum Planctomycetes-Verrucomicrobia-Chlamydiae, or PVC, have remained in relative obscurity ever since they were first described about a decade ago. Scientists at the European Molecular Biology…

2010

sciencescience-technology

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