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24 March 2025 Illustration showing four stages of cell division placed along a blue 'road’ on a green background. On top of each cell division stage, there is a coloured chromosomal trace showing how its structure grows more compact as cell division proceeds.

Illustration showing four stages of cell division placed along a blue 'road’ on a green background. On top of each cell division stage, there is a coloured chromosomal trace showing how its structure grows more compact as cell division proceeds.

How chromosomes shape up for cell division

EMBL scientists have shown how overlapping loops of DNA stack upon each other in dividing cells to give rise to rod-shaped chromosomes.

SCIENCE & TECHNOLOGY

2025

science-technology

30 March 2023 Science illustration representing two embryos imaged using the Brillouin microscopy technique. The embryo in the front is a mouse embryo at 20h and the one in the back a Phallusia mammillata embryo. A laser beam crosses the samples to analyse tissue stiffness (here represented by acoustic waves).

Science illustration representing two embryos imaged using the Brillouin microscopy technique. The embryo in the front is a mouse embryo at 20h and the one in the back a Phallusia mammillata embryo. A laser beam crosses the samples to analyse tissue stiffness (here represented by acoustic waves).

Shining light on the mechanics of embryo development

A new microscope built by EMBL researchers, based on Brillouin scattering principles, allows scientists to observe the dynamics of mechanical properties inside developing embryos in real time.

LAB MATTERS SCIENCE & TECHNOLOGY

2023

lab-matterssciencescience-technology

4 January 2023 Confocal microscopy of dynamic concentration of nucleoporins (top) and 3D model of postmitotic assembly pathway of the nuclear pore complex over a time scope of 60 minutes during cell division.

Confocal microscopy of dynamic concentration of nucleoporins (top) and 3D model of postmitotic assembly pathway of the nuclear pore complex over a time scope of 60 minutes during cell division.

Step-by-step guide to nuclear pore complex assembly

EMBL Heidelberg researchers and their collaborators reveal how the nuclear pore complex, one of the biggest molecular machines in eukaryotic cells, is assembled one protein at a time.

SCIENCE & TECHNOLOGY

2023

sciencescience-technology

6 July 2021 Photo of a building with blue sky in the background

Photo of a building with blue sky in the background

New life science Imaging Centre preparing for user access

The EMBL Imaging Centre is preparing for external user access, after an on-time and on-budget build and handover to the science team.

CONNECTIONS LAB MATTERS

2021

connectionslab-matters

28 April 2020

Dancing chromosomes

In human cells, the genetic material is packaged into 23 different DNA molecules, the chromosomes. Each chromosome is present in two copies, one inherited from the paternal sperm, and the other from the maternal egg. During most of the cell’s life, chromosomes take the shape of long,…

SCIENCE & TECHNOLOGY

2020

picture-of-the-weekscience-technology

21 January 2020

Judith Reichmann receives Paul Ehrlich prize

Judith Reichmann will receive this year’s Paul Ehrlich and Ludwig Darmstaedter Prize for Young Researchers

EMBL ANNOUNCEMENTS LAB MATTERS

2020

embl-announcementslab-matters

17 December 2019

Building Euro-BioImaging

EMBL’s Jan Ellenberg reflects on the process of forming a European research infrastructure

LAB MATTERS

2019

lab-matters

7 November 2019 IMAGE: EMBL

IMAGE: EMBL

Integrating imaging research across Europe

Euro-BioImaging now established as a European Research Infrastructure Consortium

CONNECTIONS LAB MATTERS

2019

connectionslab-matters

10 September 2019

Tracking the beginning of life

All mammalian life starts with the fusion of egg and sperm, resulting in the creation of a single cell called a zygote. This develops into an embryo through a series of cell divisions, in which the number of cells doubles at each step. Todays’ Picture of the Week was taken by Manuel Eguren of the…

SCIENCE & TECHNOLOGY

2019

picture-of-the-weekscience-technology

10 September 2018 A dynamic protein atlas of a human cell. IMAGE: Aleksandra Krolik/EMBL

A dynamic protein atlas of a human cell. IMAGE: Aleksandra Krolik/EMBL

First interactive model of human cell division

Real-time tracking of proteins during mitosis is now possible using a 4D computer model

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

12 July 2018 Artistic 3D rendering of the dual spindle in the mammalian zygote. IMAGE: Cartasiova, Hossain, Reichmann, Ellenberg/EMBL

Artistic 3D rendering of the dual spindle in the mammalian zygote. IMAGE: Cartasiova, Hossain, Reichmann, Ellenberg/EMBL

Parental chromosomes kept apart during first division

Mammalian life begins differently than we thought

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

7 December 2017 An artist’s representation of the shrinking holes and expanding pores that form in the nuclear membrane of cells during mitosis

An artist’s representation of the shrinking holes and expanding pores that form in the nuclear membrane of cells during mitosis

Cells grow pores from shrinking holes

New research shows how pores form in the membrane that surrounds a cell’s nucleus

SCIENCE & TECHNOLOGY

2017

sciencescience-technology

23 September 2016

Watching nuclear pores in growing nuclei

Puzzle of nuclear pore formation in growing nuclei solved

SCIENCE & TECHNOLOGY

2016

sciencescience-technology

21 April 2016 Both the John Kendrew and Lennart Philipson Awards consist of a gold medal and a cash prize of €5,000, presented in recognition of the very special work of alumni. PHOTO: EMBL Photolab

Both the John Kendrew and Lennart Philipson Awards consist of a gold medal and a cash prize of €5,000, presented in recognition of the very special work of alumni. PHOTO: EMBL Photolab

Alumni awards

EMBL rewards the special work of alumni through the John Kendrew and Lennart Philipson awards.

EMBL ANNOUNCEMENTS

2016

alumniembl-announcements

21 April 2016 Anne Ephrussi wears the medal of the Order of Légion d’Honneur, the highest distinction in France. PHOTO: EMBL Photolab/Marietta Schupp

Anne Ephrussi wears the medal of the Order of Légion d’Honneur, the highest distinction in France. PHOTO: EMBL Photolab/Marietta Schupp

Awards & Honours

EMBL scientists regularly receive prestigious awards – meet the latest honourees.

LAB MATTERS

2016

lab-matters

17 December 2015 Digital zebrafish embryo provided the first complete developmental blueprint of a vertebrate in 2008. IMAGE: EMBL/Keller et al.

Digital zebrafish embryo provided the first complete developmental blueprint of a vertebrate in 2008. IMAGE: EMBL/Keller et al.

SPIM doctors

From initial development to a start-up company: Selective Plane Illumination Microscopy (SPIM) at EMBL.

SCIENCE & TECHNOLOGY

2015

sciencescience-technology

14 December 2015 Scientists can now view and track the first days of a mouse embryo’s life. IMAGE: EMBL/ Julius Hossain

Scientists can now view and track the first days of a mouse embryo’s life. IMAGE: EMBL/ Julius Hossain

Turning point of a lifetime

New microscope can record the first days of a mouse embryo’s life

SCIENCE & TECHNOLOGY

2015

sciencescience-technology

29 September 2015 More than 170 representatives of EMBL and its four Nordic partnerships attending the annual meeting in September.

More than 170 representatives of EMBL and its four Nordic partnerships attending the annual meeting in September.

Northern highlights

Renewals and reunions: EMBL’s Nordic partners look to the future.

CONNECTIONS LAB MATTERS

2015

connectionslab-matters

26 August 2015 Hands-on sessions were a crucial part of the course. PHOTO: EMBL Photolab/Marietta Schupp

Hands-on sessions were a crucial part of the course. PHOTO: EMBL Photolab/Marietta Schupp

Super impressions

"It's like living a review!" Participants of recent super-resolution microscopy course share their highlights

CONNECTIONS

2015

connectionsevents

24 August 2015

Celebrating excellence

EMBL rewards the special work of alumni through the John Kendrew and Lennart Philipson awards.

PEOPLE & PERSPECTIVES

2015

alumnipeople-perspectives

20 August 2015

First, find your membrane

Collaboration between scientists reveals collaboration between lipids.

SCIENCE & TECHNOLOGY

2015

sciencescience-technology

9 April 2015 CORBEL: coordinated by ELIXIR

CORBEL: coordinated by ELIXIR

CORBEL: bridging research infrastructures

Major EU funding for CORBEL, facilitating access to data and biological imaging facilities.

LAB MATTERS

2015

lab-matters

16 March 2015

No humans required

New fully automated technique enables scientists to chart complex protein networks in living cells.

SCIENCE & TECHNOLOGY

2015

sciencescience-technology

20 October 2014

Breaking boundaries

How Nobel-winning work by alumnus Stefan Hell shapes and inspires current EMBL scientists' research.

SCIENCE & TECHNOLOGY

2014

sciencescience-technology

17 October 2014 Close-up of flow cytometer

Close-up of flow cytometer

Go with the flow

Flow cytometry: finding needles in haystacks

SCIENCE & TECHNOLOGY

2014

sciencescience-technology

18 August 2011 Circling chromosomes. Chromosomes (blue) form a ‘belt’ around the centre of the spindle (green), discovered by the EMBL scientists.

Circling chromosomes. Chromosomes (blue) form a ‘belt’ around the centre of the spindle (green), discovered by the EMBL scientists.

Fishing games gone wrong

When an egg cell is being formed, the cellular machinery which separates chromosomes is extremely imprecise at fishing them out of the cell’s interior, scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have discovered. The unexpected degree of trial-and-error…

SCIENCE & TECHNOLOGY

2011

sciencescience-technology

23 January 2011 Micropilot detected cells at particular stages of cell division

Micropilot detected cells at particular stages of cell division

Intelligent microscopy

The sight of a researcher sitting at a microscope for hours, painstakingly searching for the right cells, may soon be a thing of the past, thanks to new software created by scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany. Presented today in Nature Methods, the…

SCIENCE & TECHNOLOGY

2011

sciencescience-technology

2 December 2010 Euro-BioImaging will provide open access to state-of-the-art biological imaging techniques like fluorescence microscopy, which produced this snapshot of chromosomes (blue) being pulled apart in a dividing egg. Image credits: EMBL/ T. Kitajima

Euro-BioImaging will provide open access to state-of-the-art biological imaging techniques like fluorescence microscopy, which produced this snapshot of chromosomes (blue) being pulled apart in a dividing egg. Image credits: EMBL/ T. Kitajima

Better imaging from bench to bedside

From microscopy to computer tomography (CT) scans, imaging plays an important role in biological and biomedical research, but obtaining high-quality images often requires advanced technology and expertise, and can be costly. Euro-BioImaging, a project which launches its preparatory phase today,…

SCIENCE & TECHNOLOGY

2010

sciencescience-technology

1 April 2010

Each of these large images of dividing cells is composed of several microscopy images of human cells in which different individual genes were silenced. The smaller images are placed according to genes’ effects: images for genes that affect chromosomes make up the chromosomes (red/pink), while the mitotic spindle (green) is composed of images for genes that affect it. IMAGE: Thomas Walter & Mayumi Isokane / EMBL

Movies for the human genome

Name a human gene, and you’ll find a movie online showing you what happens to cells when it is switched off. This is the resource that researchers at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and their collaborators in the Mitocheck consortium are making freely…

SCIENCE & TECHNOLOGY

2010

sciencescience-technology

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